Michael K Lo

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Evaluation of luciferase and GFP-expressing Nipah viruses for rapid quantitative antiviral screening
    Michael K Lo
    Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    Antiviral Res 106:53-60. 2014
  2. pmc Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters
    Michael K Lo
    Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    Antiviral Res 101:26-9. 2014
  3. pmc Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response
    Michael K Lo
    Centers for Disease Control and Prevention, Viral Special Pathogens Branch, Atlanta, Georgia, United States of America
    PLoS ONE 7:e47790. 2012
  4. pmc Characterization of Nipah virus from outbreaks in Bangladesh, 2008-2010
    Michael K Lo
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 18:248-55. 2012
  5. ncbi request reprint Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neurons
    Michael K Lo
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 404:78-88. 2010
  6. pmc Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro
    Mohamad Aljofan
    Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Australia
    Virol J 6:187. 2009
  7. doi request reprint Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells
    Michael K Lo
    Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, Atlanta, GA 30333, USA
    J Gen Virol 90:398-404. 2009
  8. pmc Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA
    Cheng Feng Chiang
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Virol J 7:115. 2010
  9. ncbi request reprint Molecular virology of the henipaviruses
    Paul A Rota
    MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Curr Top Microbiol Immunol 359:41-58. 2012
  10. doi request reprint The C, V and W proteins of Nipah virus inhibit minigenome replication
    Katrina Sleeman
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Gen Virol 89:1300-8. 2008

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Evaluation of luciferase and GFP-expressing Nipah viruses for rapid quantitative antiviral screening
    Michael K Lo
    Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    Antiviral Res 106:53-60. 2014
    ..These reporter NiVs will not only facilitate antiviral screening, but also the study of host cell components that influence the virus life cycle. ..
  2. pmc Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters
    Michael K Lo
    Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    Antiviral Res 101:26-9. 2014
    ..This highly effective single-dose protection coupled with an enhanced safety profile makes these candidates ideal for potential use in livestock and humans. ..
  3. pmc Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response
    Michael K Lo
    Centers for Disease Control and Prevention, Viral Special Pathogens Branch, Atlanta, Georgia, United States of America
    PLoS ONE 7:e47790. 2012
    ..The results of this study also provide an opportunity to verify the results of earlier artificial plasmid expression studies in the context of authentic viral infection...
  4. pmc Characterization of Nipah virus from outbreaks in Bangladesh, 2008-2010
    Michael K Lo
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 18:248-55. 2012
    ..Sequence comparisons between the open reading frames of all available NiV genes led us to propose a standardized protocol for genotyping NiV; this protcol provides a simple and accurate way to classify current and future NiV sequences...
  5. ncbi request reprint Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neurons
    Michael K Lo
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 404:78-88. 2010
    ....
  6. pmc Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro
    Mohamad Aljofan
    Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Australia
    Virol J 6:187. 2009
    ..Lead compounds were then further characterised to determine the median efficacy (IC50), cytotoxicity (CC50) and the in vitro therapeutic index in live virus and pseudotype assay formats...
  7. doi request reprint Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells
    Michael K Lo
    Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, Atlanta, GA 30333, USA
    J Gen Virol 90:398-404. 2009
    ..All proteins were detected in both infected cells and purified virions. In infected cells, the W protein was detected in the nucleus while P, V and C were found in the cytoplasm...
  8. pmc Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA
    Cheng Feng Chiang
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Virol J 7:115. 2010
    ..Outbreaks of Hendra (HeV) and Nipah (NiV) viruses have been reported starting in 1994 and 1998, respectively. Both viruses are capable of causing fatal disease in humans and effecting great economical loss in the livestock industry...
  9. ncbi request reprint Molecular virology of the henipaviruses
    Paul A Rota
    MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Curr Top Microbiol Immunol 359:41-58. 2012
    ..This chapter provides an overview of the molecular virology of NiV and HeV including comparisons to other, well-characterized paramyxoviruses. This chapter also describes the sequence diversity present among the henipaviruses...
  10. doi request reprint The C, V and W proteins of Nipah virus inhibit minigenome replication
    Katrina Sleeman
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Gen Virol 89:1300-8. 2008
    ..Although there is very limited amino acid sequence similarity between the C, V and W proteins within the paramyxoviruses, the heterotypic inhibition of replication suggests that these proteins may share functional properties...
  11. pmc Development of a neutralization assay for Nipah virus using pseudotype particles
    Azaibi Tamin
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Virol Methods 160:1-6. 2009
    ..Therefore, this new method has the potential to be a rapid and cost-effective diagnostic method, especially in locations that lack high containment facilities, and will provide a valuable tool for basic research and vaccine development...
  12. doi request reprint The emergence of Nipah virus, a highly pathogenic paramyxovirus
    Michael K Lo
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 43:396-400. 2008
    ..Recent developments in diagnostics may expedite disease diagnosis and outbreak containment, while progress in understanding the molecular biology of Nipah virus could lead to novel therapeutics and vaccines for this deadly pathogen...
  13. doi request reprint Activation and cell death in human dendritic cells infected with Nipah virus
    Manisha Gupta
    Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 441:49-56. 2013
    ..Interestingly, DCs treated with inactivated NiV also show signs of apoptosis. These findings indicate that NiV infected DCs could play an important role in NiV pathogenesis...
  14. ncbi request reprint Small interfering RNA inhibition of andes virus replication
    Cheng Feng Chiang
    Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 9:e99764. 2014
    ..Taken together, our findings indicate that siRNAs targeting the ANDV genome efficiently inhibit ANDV replication, and show promise as a strategy for developing therapeutics against ANDV infection. ..