Research Topics
Species | Michael K LoSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Distinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral responseMichael K Lo
Centers for Disease Control and Prevention, Viral Special Pathogens Branch, Atlanta, Georgia, United States of America
PLoS ONE 7:e47790. 2012..The results of this study also provide an opportunity to verify the results of earlier artificial plasmid expression studies in the context of authentic viral infection...
Characterization of Nipah virus from outbreaks in Bangladesh, 2008-2010Michael K Lo
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 18:248-55. 2012..Sequence comparisons between the open reading frames of all available NiV genes led us to propose a standardized protocol for genotyping NiV; this protcol provides a simple and accurate way to classify current and future NiV sequences...
Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neuronsMichael K Lo
Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 404:78-88. 2010....
Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitroMohamad Aljofan
Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Australia
Virol J 6:187. 2009..Lead compounds were then further characterised to determine the median efficacy (IC50), cytotoxicity (CC50) and the in vitro therapeutic index in live virus and pseudotype assay formats...
Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cellsMichael K Lo
Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, Atlanta, GA 30333, USA
J Gen Virol 90:398-404. 2009..All proteins were detected in both infected cells and purified virions. In infected cells, the W protein was detected in the nucleus while P, V and C were found in the cytoplasm...
Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISACheng Feng Chiang
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Virol J 7:115. 2010..Outbreaks of Hendra (HeV) and Nipah (NiV) viruses have been reported starting in 1994 and 1998, respectively. Both viruses are capable of causing fatal disease in humans and effecting great economical loss in the livestock industry...
Molecular virology of the henipavirusesPaul A Rota
MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Curr Top Microbiol Immunol 359:41-58. 2012..This chapter provides an overview of the molecular virology of NiV and HeV including comparisons to other, well-characterized paramyxoviruses. This chapter also describes the sequence diversity present among the henipaviruses...
The C, V and W proteins of Nipah virus inhibit minigenome replicationKatrina Sleeman
Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Gen Virol 89:1300-8. 2008..Although there is very limited amino acid sequence similarity between the C, V and W proteins within the paramyxoviruses, the heterotypic inhibition of replication suggests that these proteins may share functional properties...
Development of a neutralization assay for Nipah virus using pseudotype particlesAzaibi Tamin
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Virol Methods 160:1-6. 2009..Therefore, this new method has the potential to be a rapid and cost-effective diagnostic method, especially in locations that lack high containment facilities, and will provide a valuable tool for basic research and vaccine development...
The emergence of Nipah virus, a highly pathogenic paramyxovirusMichael K Lo
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Virol 43:396-400. 2008..Recent developments in diagnostics may expedite disease diagnosis and outbreak containment, while progress in understanding the molecular biology of Nipah virus could lead to novel therapeutics and vaccines for this deadly pathogen...
Activation and cell death in human dendritic cells infected with Nipah virusManisha Gupta
Viral Special Pathogens Branch, NCEZID, DHCPP, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA Electronic address
Virology 441:49-56. 2013..Interestingly, DCs treated with inactivated NiV also show signs of apoptosis. These findings indicate that NiV infected DCs could play an important role in NiV pathogenesis...
