Research Topics
| Yu LiSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
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Detail Information
Publications
GC content-based pan-pox universal PCR assays for poxvirus detectionYu Li
Centers for Disease Control and Prevention, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Division of Viral and Rickettsial Diseases, Poxvirus and Rabies Branch, Atlanta, Georgia 30329, USA
J Clin Microbiol 48:268-76. 2010..The pan-pox assays represent an important advance for the screening and diagnosis of human and animal poxvirus infections, and the technology used is accessible to many laboratories worldwide...- The phylogenetics and ecology of the orthopoxviruses endemic to North AmericaGinny L Emerson
Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention CCID CDC, Atlanta, Georgia, USA
PLoS ONE 4:e7666. 2009..Additionally, the substantial genetic distances that separate the currently described NA OPXV species indicate that it is likely that many more undescribed OPXV/NA OPXV species may be circulating among wild animals in North America... - Detection of North American orthopoxviruses by real time-PCRNadia F Gallardo-Romero
Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, GA 30333, USA
Virol J 8:313. 2011..Thus, our assay is a promising tool for highly sensitive and specific detection of North American orthopoxviruses in the United States and abroad... 
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNAYu Li
Poxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology Proposed, National Center for Emerging and Zoonotic Infectious Diseases proposed, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States
J Virol Methods 169:223-7. 2010....- On the origin of smallpox: correlating variola phylogenics with historical smallpox recordsYu Li
Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Coordinating Centers for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Proc Natl Acad Sci U S A 104:15787-92. 2007..All of these analyses indicate that the divergence of alastrim and variola major occurred earlier than previously believed... - Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001Edith R Lederman
National Center for Zoonotic Vector Borne and Enteric Disease, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Infect Dis 206:1372-85. 2012..This case demonstrates the need for continued development of novel anti-orthopoxvirus pharmaceuticals and the importance of both intensive and timely clinical and laboratory support in management of PV... - Novel deer-associated parapoxvirus infection in deer huntersAmira A Roess
Epidemic Intelligence Service, Epidemiology Program Office, and the Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
N Engl J Med 363:2621-7. 2010..Deer populations continue to increase, leading to the possibility that there will be more deer-associated parapoxvirus infections... 
Monkeypox zoonotic associations: insights from laboratory evaluation of animals associated with the multi-state US outbreakChristina L Hutson
Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 76:757-68. 2007..These data extend the potential host range for monkeypox virus infection and supports concern regarding the potential for establishment in novel reservoir species and ecosystems...- Transmission of atypical varicella-zoster virus infections involving palm and sole manifestations in an area with monkeypox endemicityAdam MacNeil
National Center for Zoonotic, Vector Borne, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 48:e6-8. 2009..Genotyping results confirmed the VZV strain European E2, a genotype not previously reported in Africa. VZV with palm and sole involvement should be considered when differentiating a monkeypox diagnosis... - Orthopoxvirus pan-genomic DNA assayYu Li
Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
J Virol Methods 141:154-65. 2007.... - Genome sequence diversity and clues to the evolution of variola (smallpox) virusJoseph J Esposito
Biotechnology Core Facility Branch, Division of Scientific Resources, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Science 313:807-12. 2006..Knowing the sequences will help understand the viral proteome and improve diagnostic test precision, therapeutics, and systems for their assessment... - Chasing Jenner's vaccine: revisiting cowpox virus classificationDarin S Carroll
Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 6:e23086. 2011.... - Real-time PCR assay to identify variants of Vaccinia virus: implications for the diagnosis of bovine vaccinia in BrazilGiliane de Souza Trindade
Division of Viral and Rickettsial Diseases National Center for Zoonotic, Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States
J Virol Methods 152:63-71. 2008..In addition, these methods were able to detect orthopoxvirus viral DNA in lesion biopsy material without the need for DNA extraction... - Detection of monkeypox virus with real-time PCR assaysYu Li
Poxvirus Program, Division of Viral and Rickettsial Diseases, National Centers of Infectious Diseases, Centers for Disease Control and Prevention, Mail Stop G-43, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
J Clin Virol 36:194-203. 2006..Using two discrete viral gene targets, these assays together provide a reliable and sensitive method for quickly confirming monkeypox infections... - Vaccinia virus infections in martial arts gym, Maryland, USA, 2008Christine M Hughes
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 17:730-3. 2011..We report on a cluster of 4 cases of vaccinia virus infection in Maryland, USA, likely acquired at a martial arts gym... - A tale of two clades: monkeypox virusesAnna M Likos
National Center for Infectious Disease, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop G43, Atlanta, GA 30333, USA
J Gen Virol 86:2661-72. 2005..Understanding the molecular pathogenesis and clinical and epidemiological properties of MPXV can improve monkeypox prevention and control... - ORF virus infection in children: clinical characteristics, transmission, diagnostic methods, and future therapeuticsEdith R Lederman
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 26:740-4. 2007..Clinician recognition is important in distinguishing orf infection from life-threatening cutaneous zoonoses. Recently developed molecular techniques provide diagnostic precision and newer topical therapeutics may hasten healing... - Investigation of the first laboratory-acquired human cowpox virus infection in the United StatesAndrea M McCollum
Poxvirus Team, Poxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 206:63-8. 2012..This report describes the occurrence of the first known human case of laboratory-acquired cowpox virus infection in the United States and the ensuing investigation... - Serologic evidence for circulating orthopoxviruses in peridomestic rodents from rural UgandaJohanna S Salzer
Program in Population Biology, Ecology, and Evolution, Emory University, Atlanta, Georgia 30322, USA
J Wildl Dis 49:125-31. 2013..We conclude that an OPXV or a similar poxvirus is circulating among wild rodents in Uganda. With the known geographic range of OPXV in rodents now increased, factors that dictate OPXV prevalence and disease will be identified... - Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimodEdith R Lederman
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 44:e100-3. 2007..The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy...