M L Levin

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Crossbreeding between different geographical populations of the brown dog tick, Rhipicephalus sanguineus (Acari: Ixodidae)
    M L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mail Stop G 13, Atlanta, GA 30333, USA
    Exp Appl Acarol 58:51-68. 2012
  2. doi request reprint Domestic dogs (Canis familiaris) as reservoir hosts for Rickettsia conorii
    Michael L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 12:28-33. 2012
  3. ncbi request reprint Acquisition of different isolates of Anaplasma phagocytophilum by Ixodes scapularis from a model animal
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Vector Borne Zoonotic Dis 4:53-9. 2004
  4. ncbi request reprint Effects of Rickettsia conorii infection on the survival of Rhipicephalus sanguineus ticks
    M L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Microbiol Infect 15:277-8. 2009
  5. doi request reprint Incongruent effects of two isolates of Rickettsia conorii on the survival of Rhipicephalus sanguineus ticks
    M L Levin
    Rickettsial Zoonoses Branch, Mail Stop G 13, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Exp Appl Acarol 49:347-59. 2009
  6. pmc Reinfection with Anaplasma phagocytophilum in BALB/c mice and cross-protection between two sympatric isolates
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    Infect Immun 72:4723-30. 2004
  7. ncbi request reprint Comparison of the reservoir competence of medium-sized mammals and Peromyscus leucopus for Anaplasma phagocytophilum in Connecticut
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 2:125-36. 2002
  8. ncbi request reprint Interference between the agents of Lyme disease and human granulocytic ehrlichiosis in a natural reservoir host
    M L Levin
    Yale School of Medicine, Department of Epidemiology and Public Health, New Haven, CT, USA
    Vector Borne Zoonotic Dis 1:139-48. 2001
  9. doi request reprint Co-feeding as a route for transmission of Rickettsia conorii israelensis between Rhipicephalus sanguineus ticks
    G Zemtsova
    Rickettsial Zoonoses Branch, Mail Stop G 13, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Exp Appl Acarol 52:383-92. 2010
  10. ncbi request reprint Comparative vector competence of Dermacentor variabilis and Ixodes scapularis (Acari: Ixodidae) for the agent of human granulocytic ehrlichiosis
    F des Vignes
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    J Med Entomol 36:182-5. 1999

Collaborators

Detail Information

Publications33

  1. doi request reprint Crossbreeding between different geographical populations of the brown dog tick, Rhipicephalus sanguineus (Acari: Ixodidae)
    M L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mail Stop G 13, Atlanta, GA 30333, USA
    Exp Appl Acarol 58:51-68. 2012
    ..Our results demonstrate that Rh. sanguineus ticks from North America and Israel represent the same species, whereas the African population used in this study is significantly distant and probably represents a different taxon...
  2. doi request reprint Domestic dogs (Canis familiaris) as reservoir hosts for Rickettsia conorii
    Michael L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 12:28-33. 2012
    ..conorii. In addition, dogs with different genetic backgrounds appear to differ in their susceptibility to R. conorii infection...
  3. ncbi request reprint Acquisition of different isolates of Anaplasma phagocytophilum by Ixodes scapularis from a model animal
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Vector Borne Zoonotic Dis 4:53-9. 2004
    ..However, it appears unlikely that described differences in agent acquisition by ticks alone are sufficient to account for the irregular distribution of A. phagocytophilum in vector populations...
  4. ncbi request reprint Effects of Rickettsia conorii infection on the survival of Rhipicephalus sanguineus ticks
    M L Levin
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Microbiol Infect 15:277-8. 2009
  5. doi request reprint Incongruent effects of two isolates of Rickettsia conorii on the survival of Rhipicephalus sanguineus ticks
    M L Levin
    Rickettsial Zoonoses Branch, Mail Stop G 13, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Exp Appl Acarol 49:347-59. 2009
    ..The vertebrate host may be a more important reservoir than previously thought, or co-feeding transmission between different generations of ticks may obviate or lessen the requirement for transovarial maintenance of R. conorii...
  6. pmc Reinfection with Anaplasma phagocytophilum in BALB/c mice and cross-protection between two sympatric isolates
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    Infect Immun 72:4723-30. 2004
    ..phagocytophilum did not protect mice from a challenge with either homologous or heterologous isolates, however the ensuing reinfection was significantly milder and of a shorter duration than the first infection with either isolate...
  7. ncbi request reprint Comparison of the reservoir competence of medium-sized mammals and Peromyscus leucopus for Anaplasma phagocytophilum in Connecticut
    Michael L Levin
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 2:125-36. 2002
    ..Thus, raccoons and gray squirrels are reservoir-competent for the agent of HGE-they become naturally infected, and are capable of transmitting the infection to feeding ticks...
  8. ncbi request reprint Interference between the agents of Lyme disease and human granulocytic ehrlichiosis in a natural reservoir host
    M L Levin
    Yale School of Medicine, Department of Epidemiology and Public Health, New Haven, CT, USA
    Vector Borne Zoonotic Dis 1:139-48. 2001
    ..phagocytophila than mice infected with E. phagocytophila only. Thus, a primary infection with either B. burgdorferi or E. phagocytophila in mice inhibited transmission of a second agent, suggesting interference between these two agents...
  9. doi request reprint Co-feeding as a route for transmission of Rickettsia conorii israelensis between Rhipicephalus sanguineus ticks
    G Zemtsova
    Rickettsial Zoonoses Branch, Mail Stop G 13, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Exp Appl Acarol 52:383-92. 2010
    ..conorii israelensis between co-feeding ticks upon both naïve and seropositive dogs. This route of transmission can ensure continuous circulation of R. conorii israelensis in tick vectors even in the absence of naïve reservoir hosts...
  10. ncbi request reprint Comparative vector competence of Dermacentor variabilis and Ixodes scapularis (Acari: Ixodidae) for the agent of human granulocytic ehrlichiosis
    F des Vignes
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    J Med Entomol 36:182-5. 1999
    ..Evidence of transmission was not observed in any of 9 mice exposed to D. variabilis nymphs. These results demonstrate that although I. scapularis is a competent vector of the agent of the HGF, D. variabilis is not...
  11. pmc Patterns of condom use among adolescents: the impact of mother-adolescent communication
    K S Miller
    Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Public Health 88:1542-4. 1998
    ..The association between the timing of discussions about condoms between mother and adolescent and adolescents' condom use during their first and subsequent sexual encounters was examined...
  12. ncbi request reprint Detection of Rickettsia, Borrelia, and Bartonella in Carios kelleyi (Acari: Argasidae)
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Entomol 42:473-80. 2005
    ..turicatae, was detected in one of 31 live ticks. The 16S-23S intergenic spacer region of Bartonella henselae also was detected in one of 31 live ticks. Coxiella or A. phagocytophilum DNA were not detected in these ticks...
  13. doi request reprint A sustained-release formulation of doxycycline hyclate (Atridox) prevents simultaneous infection of Anaplasma phagocytophilum and Borrelia burgdorferi transmitted by tick bite
    Nordin S Zeidner
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    J Med Microbiol 57:463-8. 2008
    ..These studies indicate that a single injection of a sustained-release formulation antibiotic may offer a viable prophylactic treatment option for multiple infectious agents in patients presenting with tick bites...
  14. doi request reprint Two USA Ehrlichia spp. cause febrile illness in goats
    Amanda D Loftis
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Vet Microbiol 130:398-402. 2008
    ..In the eastern USA, undifferentiated febrile illness in goats might be caused by previously unrecognized ehrlichial infections, and pastures housing-infected goats could become infested with a large number of infected ticks...
  15. ncbi request reprint Route of transmission alters the infectivity of Anaplasma phagocytophila in mice
    Robert F Massung
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Ann N Y Acad Sci 990:494-5. 2003
  16. pmc Isolation and propagation of the Ap-Variant 1 strain of Anaplasma phagocytophilum in a tick cell line
    Robert F Massung
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    J Clin Microbiol 45:2138-43. 2007
    ..phagocytophilum with pleomorphic bacteria in membrane-bound vacuoles and both electron-dense and electron-lucent forms...
  17. ncbi request reprint Transmission efficiency of the AP-variant 1 strain of Anaplasma phagocytophila
    Robert F Massung
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Ann N Y Acad Sci 990:75-9. 2003
    ....
  18. ncbi request reprint Isolation of Anaplasma phagocytophilum strain Ap-variant 1 in a tick-derived cell line
    Robert F Massung
    Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    Ann N Y Acad Sci 1078:541-4. 2006
    ..These are the first tissue culture isolates of the Ap-Variant 1 strain and will allow for further characterization of the biological and antigenic properties of this strain...
  19. ncbi request reprint Reservoir competency of goats for Anaplasma phagocytophilum
    Robert F Massung
    Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    Ann N Y Acad Sci 1078:476-8. 2006
    ..phagocytophilum. Transmission from an infected goat to a naïve goat by I. scapularis tick feeding was used to demonstrate that goats are reservoir-competent for the Ap-Variant 1 strain...
  20. ncbi request reprint Prophylactic use of sustained-release doxycycline blocks tick-transmitted infection by Anaplasma phagocytophilum in a murine model
    Robert F Massung
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Ann N Y Acad Sci 1063:436-8. 2005
    ..The sustained-release doxycycline formulation was shown to be efficacious for preventing tick-transmitted A. phagocytophilum infection in a mouse model...
  21. pmc Reservoir competency of goats for the Ap-variant 1 strain of Anaplasma phagocytophilum
    Robert F Massung
    Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G 13, Atlanta, GA 30333, USA
    Infect Immun 74:1373-5. 2006
    ..Goats were shown to be competent as a reservoir for Ap-Variant 1, and challenge and immunosuppression studies were used to further examine infection in the goat model...
  22. ncbi request reprint Rocky Mountain spotted fever from an unexpected tick vector in Arizona
    Linda J Demma
    National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, The Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 353:587-94. 2005
    ..This disease is rarely reported in Arizona, and the principal vectors, Dermacentor species ticks, are uncommon in the state. From 2002 through 2004, a focus of Rocky Mountain spotted fever was investigated in rural eastern Arizona...
  23. ncbi request reprint Inability of a variant strain of Anaplasma phagocytophilum to infect mice
    Robert F Massung
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 188:1757-63. 2003
    ..These data suggest that AP-variant 1 cannot establish an infection in mice, and we propose that AP-variant 1 has an alternative natural reservoir, possibly white-tailed deer...
  24. ncbi request reprint Lack of susceptibility of guinea pigs and gerbils to experimental infection with Ehrlichia chaffeensis
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 4:319-22. 2004
    ..Exposure to the pathogen was confirmed using serology. Neither guinea pigs nor gerbils were susceptible to infection with E. chaffeensis, and ticks fed upon these animals did not become infected with the pathogen...
  25. ncbi request reprint Transmission route efficacy and kinetics of Anaplasma phagocytophilum infection in white-footed mouse, Peromyscus leucopus
    Robert F Massung
    Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseaes, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 4:310-8. 2004
    ....
  26. ncbi request reprint Evaluation of immunocompetent and immunocompromised mice (Mus musculus) for infection with Ehrlichia chaffeensis and transmission to Amblyomma americanum ticks
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Vector Borne Zoonotic Dis 4:323-33. 2004
    ..E. chaffeensis DNA was detected in up to 55% of replete nymphs that fed on Rag1 mice. However, E. chaffeensis was not detected in molted adult ticks from the same cohorts...
  27. pmc Quantitative real-time PCR assay for detection of Ehrlichia chaffeensis
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 41:3870-2. 2003
    ..The assay is not inhibited by the presence of tick, human, or mouse DNA and is compatible with high sample throughput. The assay was compared with previously described assays for E. chaffeensis...
  28. pmc Disparity in the natural cycles of Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis
    M L Levin
    Yale School of Medicine, New Haven, Connecticut 06520 8034, USA
    Emerg Infect Dis 5:204-8. 1999
    ..The different prevalence in nature of these pathogens in ticks suggests that their maintenance cycles are also different...
  29. ncbi request reprint Infection of a goat with a tick-transmitted Ehrlichia from Georgia, U.S.A., that is closely related to Ehrlichia ruminantium
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Mail Stop G 13, Atlanta, GA 30333, USA
    J Vector Ecol 31:213-23. 2006
    ..Our data suggest that A. americanum is a natural vector and reservoir of this Ehrlichia and that domestic goats can be reservoirs. The geographic range of the agent and its pathogenicity to humans and livestock needs to be evaluated...
  30. ncbi request reprint Susceptibility of mice (Mus musculus) to repeated infestation with Amblyomma americanum (Acari: Ixodidae) ticks
    Amanda D Loftis
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Entomol 41:1171-4. 2004
    ..americanum. In contrast, tick viability was significantly reduced in the second infestation of a New Zealand White rabbit, a laboratory animal known to develop resistance to A. americanum...
  31. ncbi request reprint Spotted fever rickettsiae, Ehrlichia and Anaplasma, in ticks from peridomestic environments in Panama
    M E Eremeeva
    Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Microbiol Infect 15:12-4. 2009
  32. ncbi request reprint Effects of Anaplasma phagocytophilum infection on the molting success of Ixodes scapularis (Acari: Ixodidae) larvae
    Danielle E Ross
    Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Entomol 41:476-83. 2004
    ..Noted differences between isolates may be due to the origin of a particular isolate and/or the degree of coadaptation between the pathogen and its vector on the population level...
  33. ncbi request reprint Life cycles of seven ixodid tick species (Acari: Ixodidae) under standardized laboratory conditions
    Danielle R Troughton
    Rickettsial Zoonoses Branch, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Entomol 44:732-40. 2007
    ..scapularis, 204-219 d; I. pacificus, 214-229 d; R. sanguineus, 162-177 d; H. leporispalustris, 209-224 d; D. variabilis, 176-191 d; D. occidentalis, 180-195 d; and A. americanum, 192-211 d...