Eileen D Kuempel

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Pulmonary inflammation and crystalline silica in respirable coal mine dust: dose-response
    E D Kuempel
    National Institute for Occupational Safety and Health NIOSH, Education and Information Division, Risk Evaluation Branch, Cincinnati, OH 45226 1998, USA
    J Biosci 28:61-9. 2003
  2. ncbi request reprint Methodological issues of using observational human data in lung dosimetry models for particulates
    E D Kuempel
    National Institute for Occupational Safety and Health, Cincinnati, OH, USA
    Sci Total Environ 274:67-77. 2001
  3. doi request reprint Carbon nanotube risk assessment: implications for exposure and medical monitoring
    Eileen D Kuempel
    Education and Information Division, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    J Occup Environ Med 53:S91-7. 2011
  4. doi request reprint Risk assessment and risk management of nanomaterials in the workplace: translating research to practice
    Eileen D Kuempel
    National Institute for Occupational Safety and Health NIOSH, Education and Information Division, Nanotechnology Research Center, Cincinnati, OH 45226, USA
    Ann Occup Hyg 56:491-505. 2012
  5. doi request reprint Contributions of dust exposure and cigarette smoking to emphysema severity in coal miners in the United States
    Eileen D Kuempel
    National Institute for Occupational Safety and Health, Education and Information Division, Risk Evaluation Branch, Cincinnati, Ohio 45226 1998, USA
    Am J Respir Crit Care Med 180:257-64. 2009
  6. ncbi request reprint Lung dosimetry and risk assessment of nanoparticles: evaluating and extending current models in rats and humans
    E D Kuempel
    National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    Inhal Toxicol 18:717-24. 2006
  7. ncbi request reprint Biological and statistical approaches to predicting human lung cancer risk from silica
    E D Kuempel
    National Institute for Occupational Safety and Health, Education and Information Division, Risk Evaluation Branch, Cincinnati, OH 45226 1998, USA
    J Environ Pathol Toxicol Oncol 20:15-32. 2001
  8. doi request reprint Focused actions to protect carbon nanotube workers
    Paul A Schulte
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA
    Am J Ind Med 55:395-411. 2012
  9. ncbi request reprint Development of a fibre size-specific job-exposure matrix for airborne asbestos fibres
    J M Dement
    Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University Medical Center, 2200 W Main Street, Suite 400, Durham, NC 27705, USA
    Occup Environ Med 65:605-12. 2008
  10. doi request reprint Mortality among U.S. underground coal miners: a 23-year follow-up
    M D Attfield
    Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health NIOSH, Morgantown, West Virginia 26505, USA
    Am J Ind Med 51:231-45. 2008

Detail Information

Publications13

  1. ncbi request reprint Pulmonary inflammation and crystalline silica in respirable coal mine dust: dose-response
    E D Kuempel
    National Institute for Occupational Safety and Health NIOSH, Education and Information Division, Risk Evaluation Branch, Cincinnati, OH 45226 1998, USA
    J Biosci 28:61-9. 2003
    ..4). This study demonstrates dose-response relationships between respirable crystalline silica in coal mine dust and pulmonary inflammation, antioxidant production, and radiographic small opacities...
  2. ncbi request reprint Methodological issues of using observational human data in lung dosimetry models for particulates
    E D Kuempel
    National Institute for Occupational Safety and Health, Cincinnati, OH, USA
    Sci Total Environ 274:67-77. 2001
    ..A challenge in using these data is their often sparse, heterogeneous nature, which may require special methods. Approaches for evaluating sources of variability and uncertainty in a human lung dosimetry model are described in this study...
  3. doi request reprint Carbon nanotube risk assessment: implications for exposure and medical monitoring
    Eileen D Kuempel
    Education and Information Division, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    J Occup Environ Med 53:S91-7. 2011
    ..Quantitative risk estimates using toxicology data provide information for risk management to protect workers with potential exposure to carbon nanotubes (CNTs)...
  4. doi request reprint Risk assessment and risk management of nanomaterials in the workplace: translating research to practice
    Eileen D Kuempel
    National Institute for Occupational Safety and Health NIOSH, Education and Information Division, Nanotechnology Research Center, Cincinnati, OH 45226, USA
    Ann Occup Hyg 56:491-505. 2012
    ..This article provides a state-of-the-art overview on translating current hazard research data and risk assessment methods for nanomaterials to the development and implementation of effective risk management guidance...
  5. doi request reprint Contributions of dust exposure and cigarette smoking to emphysema severity in coal miners in the United States
    Eileen D Kuempel
    National Institute for Occupational Safety and Health, Education and Information Division, Risk Evaluation Branch, Cincinnati, Ohio 45226 1998, USA
    Am J Respir Crit Care Med 180:257-64. 2009
    ..Previous studies have shown associations between dust exposure or lung burden and emphysema in coal miners, although the separate contributions of various predictors have not been clearly demonstrated...
  6. ncbi request reprint Lung dosimetry and risk assessment of nanoparticles: evaluating and extending current models in rats and humans
    E D Kuempel
    National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    Inhal Toxicol 18:717-24. 2006
    ..Such analyses would provide improved prediction of nanoparticle dose for risk assessment...
  7. ncbi request reprint Biological and statistical approaches to predicting human lung cancer risk from silica
    E D Kuempel
    National Institute for Occupational Safety and Health, Education and Information Division, Risk Evaluation Branch, Cincinnati, OH 45226 1998, USA
    J Environ Pathol Toxicol Oncol 20:15-32. 2001
    ..This study illustrates that assumptions about the relevant biological mechanism, animal model, and statistical approach can all influence the magnitude of lung cancer risk estimates in humans exposed to crystalline silica...
  8. doi request reprint Focused actions to protect carbon nanotube workers
    Paul A Schulte
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA
    Am J Ind Med 55:395-411. 2012
    ....
  9. ncbi request reprint Development of a fibre size-specific job-exposure matrix for airborne asbestos fibres
    J M Dement
    Division of Occupational and Environmental Medicine, Department of Community and Family Medicine, Duke University Medical Center, 2200 W Main Street, Suite 400, Durham, NC 27705, USA
    Occup Environ Med 65:605-12. 2008
    ..To develop a method for estimating fibre size-specific exposures to airborne asbestos dust for use in epidemiological investigations of exposure-response relations...
  10. doi request reprint Mortality among U.S. underground coal miners: a 23-year follow-up
    M D Attfield
    Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health NIOSH, Morgantown, West Virginia 26505, USA
    Am J Ind Med 51:231-45. 2008
    ..The mortality experience over 22-24 years of 8,899 working coal miners initially medically examined in 1969-1971 at 31 U.S. coal mines was evaluated...
  11. ncbi request reprint A biomathematical model of particle clearance and retention in the lungs of coal miners. II. Evaluation of variability and uncertainty
    E D Kuempel
    Risk Evaluation Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226-1998, USA
    Regul Toxicol Pharmacol 34:88-101. 2001
    ..It is useful for risk assessment by providing estimated lung dust burdens associated with occupational exposure to respirable particles...
  12. ncbi request reprint A biomathematical model of particle clearance and retention in the lungs of coal miners
    E D Kuempel
    Department of Environmental Health, College of Medicine, University of Cincinnati, OH, USA
    Regul Toxicol Pharmacol 34:69-87. 2001
    ..This model is useful for risk assessment of particle-induced lung diseases, by estimating equivalent internal doses in rodents and humans and predicting lung burdens in humans with occupational dust exposures...
  13. ncbi request reprint Pneumoconiosis, coalmine dust and the PFR
    M D Attfield
    Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Ann Occup Hyg 47:525-9. 2003