Research Topics
| Olen KewSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
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Detail Information
Publications
Reaching the last one per cent: progress and challenges in global polio eradicationOlen Kew
Division of Viral Diseases, G 10, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Curr Opin Virol 2:188-98. 2012....
Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirusOlen Kew
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention CDC, 1600 Clifton Road, Atlanta, GA 30333, USA
Science 296:356-9. 2002..The vaccine-derived poliovirus associated with the outbreak had biological properties indistinguishable from those of wild poliovirus...
Genetic inactivation of poliovirus infectivity by increasing the frequencies of CpG and UpA dinucleotides within and across synonymous capsid region codonsCara C Burns
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 83:9957-69. 2009....
Intratypic recombination among lineages of type 1 vaccine-derived poliovirus emerging during chronic infection of an immunodeficient patientChen-Fu Yang
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 79:12623-34. 2005..The appearance of a chronic VDPV excretor in a tropical, developing country has important implications for the strategy to stop OPV immunization after eradication of wild polioviruses...
Limited duration of vaccine poliovirus and other enterovirus excretion among human immunodeficiency virus infected children in KenyaNino Khetsuriani
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
BMC Infect Dis 9:136. 2009....
Calibration of multiple poliovirus molecular clocks covering an extended evolutionary rangeJaume Jorba
Polio and Picornavirus Laboratory Branch, G 10, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Virol 82:4429-40. 2008....
Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid regionCara Carthel Burns
Respiratory and Enteric Viruses Branch, G 10, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, N E, Atlanta, GA 30333, USA
J Virol 80:3259-72. 2006..Potential applications for the systematic modulation of poliovirus replicative fitness by deoptimization of codon usage are discussed...
Outbreak of type 2 vaccine-derived poliovirus in Nigeria: emergence and widespread circulation in an underimmunized populationSteven Wassilak
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 203:898-909. 2011..Strengthened routine immunization programs in countries with suboptimal coverage and balanced use of OPV formulations in SIAs are necessary to minimize risks of VDPV emergence and circulation...
Poliovirus serotype-specific VP1 sequencing primersDavid R Kilpatrick
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Virol Methods 174:128-30. 2011....
Circulation of endemic type 2 vaccine-derived poliovirus in Egypt from 1983 to 1993Chen Fu Yang
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 77:8366-77. 2003..The potential for cVDPVs to circulate in populations with low immunity to poliovirus has important implications for current and future strategies to eradicate polio worldwide...
Persistence of vaccine-derived polioviruses among immunodeficient persons with vaccine-associated paralytic poliomyelitisNino Khetsuriani
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, and National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 188:1845-52. 2003..These results are important for developing "endgame" strategies for the Global Poliomyelitis Eradication Program...
Polio today: are we on the verge of global eradication?Stephen L Cochi
Centers for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Rd NE, Mailstop E 05, Atlanta, GA 30333, USA
JAMA 300:839-41. 2008
Isolation of a type 3 vaccine-derived poliovirus (VDPV) from an Iranian child with X-linked agammaglobulinemiaShohreh Shahmahmoodi
National Polio Laboratory, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
Virus Res 137:168-72. 2008..No secondary AFP cases were found, and none of the seven tested contacts of the patient were found to be infected with poliovirus...
Co-circulation and evolution of polioviruses and species C enteroviruses in a district of MadagascarMala Rakoto Andrianarivelo
Unite de Virologie Medicale, Institut Pasteur de Madagascar, Antananarivo, Madagascar
PLoS Pathog 3:e191. 2007..This probably contributed to the emergence of recombinant VDPVs. These findings give further insight into viral ecosystems and the evolutionary processes that shape viral biodiversity...
Isolation of recombinant type 2 vaccine-derived poliovirus (VDPV) from a Nigerian childFestus Adu
National Poliovirus Laboratory, Department of Virology, College of Medicine, University of Ibadan, UCH, Ibadan, Oyo State, Nigeria
Virus Res 127:17-25. 2007..Although no related type 2 VDPVs were detected in Nigeria or elsewhere, the VDPV was found in an area where conditions favor VDPV emergence and spread...
Vaccine-derived polioviruses: is it time to stop using the word "rare"?Walter Dowdle
J Infect Dis 194:539-41. 2006
What role for inactivated poliovirus vaccine in the eradication endgame?Olen Kew
J Infect Dis 193:1341-3. 2006
Circulation of type 1 vaccine-derived poliovirus in the Philippines in 2001Hiroyuki Shimizu
Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan
J Virol 78:13512-21. 2004..Type 1 cVDPV was last detected in the Philippines in September 2001, and population immunity to polio was raised by extensive OPV campaigns in late 2001 and early 2002...
Isolation and characterization of circulating type 1 vaccine-derived poliovirus from sewage and stream waters in HispaniolaJan Vinje
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
J Infect Dis 189:1168-75. 2004..Our findings demonstrate a useful role for environmental surveillance of neurovirulent polioviruses in the overall polio eradication program...
Containment of polioviruses after eradication and OPV cessation: characterizing risks to improve managementWalter Dowdle
Polio Eradication Program, The Task Force for Child Survival and Development, 750 Commerce Dr, Suite 400, Decatur, GA 30030, USA
Risk Anal 26:1449-69. 2006..Minimizing the risk of poliovirus transmission from a poliovirus facility to increasingly susceptible communities is a crucial and ongoing effort requiring understanding and actively managing the potential exposure pathways...
No evidence for prolonged excretion of polioviruses in persons with residual paralytic poliomyelitis in Ethiopia, Pakistan and GuatemalaAamir J Khan
Department of International Health, Institute for Vaccine Safety, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Room W5041, Baltimore, MD 21205, USA
Biologicals 34:113-6. 2006..Nevertheless, persistent poliovirus excretion among persons 2 years of age and older with residual paralytic poliomyelitis is uncommon in developing countries...
