Research Topics
| Saleem KamiliSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
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Detail Information
Publications
Laboratory diagnostics for hepatitis C virus infectionSaleem Kamili
Division of Viral Hepatitis, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Clin Infect Dis 55:S43-8. 2012..The diagnosis of acute HCV infection without the demonstration of seroconversion remains elusive...
DNA vaccination against hepatitis E virus infection in cynomolgus macaquesSaleem Kamili
Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Gastroenterol Hepatol 17:S365-9. 2002....
Toward the development of a hepatitis E vaccineSaleem Kamili
Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, GA 30333, USA
Virus Res 161:93-100. 2011..However, at this time no approved vaccine against hepatitis E is commercially available...
Infectivity of hepatitis C virus in plasma after drying and storing at room temperatureSaleem Kamili
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
Infect Control Hosp Epidemiol 28:519-24. 2007..To determine effect of environmental exposure on the survival and infectivity of hepatitis C virus (HCV)...
Infectivity and vaccination efficacy studies in animal models of HBV S and pol gene mutantsSaleem Kamili
Division of Viral Hepatitis, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
Antivir Ther 15:477-85. 2010..Additional hepatitis B vaccine efficacy studies conducted in chimpanzees showed lack of sterilizing immunity against the pol mutant. Whether such mutants can transmit to and infect vaccinated humans requires further investigation...
Hepatitis E epidemic, UgandaEyasu H Teshale
Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G37, Atlanta, GA 30333, USA
Emerg Infect Dis 16:126-9. 2010..This outbreak has progressed to become one of the largest hepatitis E outbreaks in the world. By June 2009, the epidemic had caused illness in >10,196 persons and 160 deaths...
Novel risk factors associated with hepatitis E virus infection in a large outbreak in northern Uganda: results from a case-control study and environmental analysisChristopher M Howard
Division of Global Disease Detection and Emergency Response, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Trop Med Hyg 83:1170-3. 2010..The epidemiologic and environmental water-testing results suggest that household-level factors played an important role in the transmission of HEV-modalities that have been previously underappreciated...
Protective efficacy of hepatitis E virus DNA vaccine administered by gene gun in the cynomolgus macaque model of infectionSaleem Kamili
Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30084, USA
J Infect Dis 189:258-64. 2004..These results indicate that DNA vaccine with HEV ORF2 administered by gene gun is protective against a heterologous viral challenge...
Suppression of interferon-α signaling by hepatitis E virusChen Dong
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA
Hepatology 55:1324-32. 2012..CONCLUSION: HEV inhibits IFN-α signaling through the regulation of STAT1 phosphorylation in A549 cells. These findings have implications for the development of new strategies against hepatitis E...
Laboratory-based surveillance for hepatitis E virus infection, United States, 2005-2012Jan Drobeniuc
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Emerg Infect Dis 19:218-22; quiz 353. 2013..0). HEV genotype 3 was characterized from 8 nontravelers and genotypes 1 or 4 from 4 travelers. Clinicians should consider HEV infection in the differential diagnosis of hepatitis, regardless of patient travel history...
Efficacy of hepatitis B vaccine against antiviral drug-resistant hepatitis B virus mutants in the chimpanzee modelSaleem Kamili
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Hepatology 49:1483-91. 2009..In the absence of a protective humoral immunity, adaptive cellular immune responses elicited by infection may limit HBV replication and persistence...
Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performancesJan Drobeniuc
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA
Clin Infect Dis 51:e24-7. 2010..Diagnostic sensitivities and specificities as well as interassay agreement varied widely. Analytical sensitivity limits also were determined and were found to be particularly disparate...
Serological diagnostics of hepatitis E virus infectionYury Khudyakov
Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, GA 30333, USA
Virus Res 161:84-92. 2011....
Evaluation of three rapid screening assays for detection of antibodies to hepatitis C virusBryce D Smith
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 204:825-31. 2011..Although therapies are available that can suppress or eliminate infection, identifying persons infected with HCV is challenging. Rapid tests could help identify many of these persons more expeditiously...
Rapid diagnostic HCV antibody assaysBryce D Smith
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA
Antivir Ther 17:1409-13. 2012..9-99.3%) and specificity (80-100%) varied. Future investigations could include evaluation of rapid anti-HCV tests in persons who are coinfected with HCV and HIV, and development of rapid HCV-antigen tests and nucleic acid tests...
Distinguishing acute from chronic hepatitis C virus (HCV) infection based on antibody reactivities to specific HCV structural and nonstructural proteinsAufra C Araujo
Division of Viral Hepatitis, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS A 33, Atlanta, GA 30333, USA
J Clin Microbiol 49:54-7. 2011..8% for the acute group and 97.2% for the chronic group. The immunoassay described has the potential to distinguish acute from chronic HCV infection...
Persistence of hepatitis A vaccine induced seropositivity in infants and young children by maternal antibody status: 10-year follow-upUmid M Sharapov
Division of Viral Hepatitis, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
Hepatology 56:516-22. 2012..CONCLUSION: The seropositivity induced by hepatitis A vaccine given to children <2 years of age persists for at least 10 years regardless of presence of maternal anti-HAV...
Evidence of person-to-person transmission of hepatitis E virus during a large outbreak in Northern UgandaEyasu H Teshale
Division of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Atlanta, Georgia 301333, USA
Clin Infect Dis 50:1006-10. 2010..Outbreaks of infection with hepatitis E virus (HEV) are frequently attributed to contaminated drinking water, even if direct evidence for this is lacking...
Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United StatesChen Dong
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Clin Microbiol 49:4164-72. 2011..HEV infected farmed swine primarily, and the role of other animals as reservoirs of its zoonotic spread appears to be limited...
Acute hepatitis associated with autochthonous hepatitis E virus infection--San Antonio, Texas, 2009Rania A Tohme
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 53:793-6. 2011..Hepatitis E virus genotype 3a related to US-2 and swine hepatitis E virus strains was isolated from one of the patients, indicating potential food-borne or zoonotic transmission...
Persistence of long-term immunity to hepatitis B among adolescents immunized at birthSandra S Chaves
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Vaccine 30:1644-9. 2012..Future vaccine recommendations should be based on studies ascertaining protection against clinically significant disease...
Hepatitis E virus infection may be transmitted through blood transfusions in an endemic areaMohammad Sultan Khuroo
Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
J Gastroenterol Hepatol 19:778-84. 2004..CONCLUSION: Frequent transmission of HEV by blood transfusion places recipients at risk and warrants redefining of the donor screening policy by blood banks, especially in endemic areas...
Immunity to hepatitis E virus: new insights and future challengesSaleem Kamili
Indian J Gastroenterol 21:136-8. 2002
