Research Topics
| Christina L HutsonSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Transmissibility of the monkeypox virus clades via respiratory transmission: investigation using the prairie dog-monkeypox virus challenge systemChristina L Hutson
Division of High Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Diseases, Atlanta, Georgia, USA
PLoS ONE 8:e55488. 2013..7% and 0% respectively). Based on these findings, respiratory transmission appears to be less efficient than those of previous studies assessing contact as a mechanism of transmission within the prairie dog MPXV animal model...
Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus diseaseChristina L Hutson
Centers for Disease Control and Prevention MS G06 1600 Clifton Rd NE, Atlanta, GA 30333, USA
Virology 402:72-82. 2010..9x10(3) and 1.29x10(5) respectively); reinforcing previous findings that Congo Basin MPXV is more virulent...
Monkeypox disease transmission in an experimental setting: prairie dog animal modelChristina L Hutson
Poxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 6:e28295. 2011..Future use of the model will allow us to evaluate infection control measures, vaccines and antiviral strategies to decrease disease transmission...
Comparison of West African and Congo Basin monkeypox viruses in BALB/c and C57BL/6 miceChristina L Hutson
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 5:e8912. 2010..In addition, such a model can be utilized to test antivirals and the next generation of orthopoxvirus vaccines for their ability to alter the course of disease...
A prairie dog animal model of systemic orthopoxvirus disease using West African and Congo Basin strains of monkeypox virusChristina L Hutson
Centers for Disease Control and Prevention, MS G 43, Atlanta, GA 30333, USA
J Gen Virol 90:323-33. 2009..Additionally, the model closely mimics human systemic orthopoxvirus disease and may serve as a valuable non-human surrogate for investigations of antivirals and next generation orthopoxvirus vaccines...
Monkeypox zoonotic associations: insights from laboratory evaluation of animals associated with the multi-state US outbreakChristina L Hutson
Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 76:757-68. 2007..These data extend the potential host range for monkeypox virus infection and supports concern regarding the potential for establishment in novel reservoir species and ecosystems...
The pox in the North American backyard: Volepox virus pathogenesis in California mice (Peromyscus californicus)Nadia F Gallardo-Romero
Poxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e43881. 2012..Viral loads measured as high as 2 × 10(9) PFU/mL in some organs. Our results suggest that VPXV can cause extreme morbidity and mortality within rodent populations sympatric with the known VPXV reservoirs...
Monkeypox virus infections in small animal models for evaluation of anti-poxvirus agentsChristina L Hutson
Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd MS G06 Atlanta, GA 30029, USA E mail
Viruses 2:2763-76. 2010..We will review those MPXV small animal models that have been developed thus far for the study of therapeutic agents...
