Christopher A Haynes

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi HPLC-ESI-MS/MS analysis of hemoglobin peptides in tryptic digests of dried-blood spot extracts detects HbS, HbC, HbD, HbE, HbO-Arab, and HbG-Philadelphia mutations
    Christopher A Haynes
    Biochemical Mass Spectrometry Laboratory, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, Mail Stop F 19, Atlanta, GA, 30341, United States Electronic address
    Clin Chim Acta 424:191-200. 2013
  2. doi Improved analysis of C26:0-lysophosphatidylcholine in dried-blood spots via negative ion mode HPLC-ESI-MS/MS for X-linked adrenoleukodystrophy newborn screening
    Christopher A Haynes
    Newborn Screening and Molecular Biology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Clin Chim Acta 413:1217-21. 2012
  3. doi Analysis of mammalian fatty acyl-coenzyme A species by mass spectrometry and tandem mass spectrometry
    Christopher A Haynes
    Newborn Screening Quality Assurance Program, NSQAP, USA
    Biochim Biophys Acta 1811:663-8. 2011

Detail Information

Publications3

  1. doi HPLC-ESI-MS/MS analysis of hemoglobin peptides in tryptic digests of dried-blood spot extracts detects HbS, HbC, HbD, HbE, HbO-Arab, and HbG-Philadelphia mutations
    Christopher A Haynes
    Biochemical Mass Spectrometry Laboratory, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, Mail Stop F 19, Atlanta, GA, 30341, United States Electronic address
    Clin Chim Acta 424:191-200. 2013
    ..E121Q), and (c.364G>A, p.E121K), resulting in HbS (sickle-cell hemoglobin), HbC, HbE, HbD-Los Angeles, and HbO-Arab, respectively. One α-globin mutation is (c.[207C>G or 207C>A], p.N68K), resulting in HbG-Philadelphia...
  2. doi Improved analysis of C26:0-lysophosphatidylcholine in dried-blood spots via negative ion mode HPLC-ESI-MS/MS for X-linked adrenoleukodystrophy newborn screening
    Christopher A Haynes
    Newborn Screening and Molecular Biology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Clin Chim Acta 413:1217-21. 2012
    ..The biochemical defect associated with X-ALD is an accumulation of very long-chain fatty acids (VLCFA, e.g. C24:0 and C26:0), which has been shown to result in the accumulation of C26:0-lysophosphatidylcholine (C26:0-LPC)...
  3. doi Analysis of mammalian fatty acyl-coenzyme A species by mass spectrometry and tandem mass spectrometry
    Christopher A Haynes
    Newborn Screening Quality Assurance Program, NSQAP, USA
    Biochim Biophys Acta 1811:663-8. 2011
    ..e. palmitoyl-CoA), particularly reports of streamlined methodology, improved recovery, or expansion of the number of acyl chain-lengths amenable to quantitation...