Marta Gwinn

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi Public knowledge regarding the role of genetic susceptibility to environmentally induced health conditions
    Jill Morris
    Office of Genetics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS K 28, Atlanta, GA 30341 3724, USA
    Community Genet 6:22-8. 2003
  2. ncbi Genomics and public health at CDC
    Marta Gwinn
    National Office of Public Health Genomics, CDC, 4770 Buford Hwy, MS K 89, Atlanta, GA 30342, USA
    MMWR Morb Mortal Wkly Rep 55:20-1. 2006
  3. ncbi Invited commentary: genes, environment, and hybrid vigor
    Marta Gwinn
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Epidemiol 170:703-7. 2009
  4. ncbi Genomics and public health in the United States: signposts on the translation highway
    Marta Gwinn
    Office of Genomics and Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Community Genet 9:21-6. 2006
  5. ncbi Horizon scanning for new genomic tests
    Marta Gwinn
    McKing Consulting Corporation, Atlanta, Georgia, USA
    Genet Med 13:161-5. 2011
  6. ncbi GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 9:205. 2008
  7. ncbi GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studies
    Wei Yu
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 19:1095-9. 2011
  8. ncbi An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiology
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 8:436. 2007
  9. ncbi Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment
    Ajay Yesupriya
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
    BMC Med Res Methodol 8:31. 2008
  10. ncbi HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 16:1155-8. 2008

Detail Information

Publications57

  1. ncbi Public knowledge regarding the role of genetic susceptibility to environmentally induced health conditions
    Jill Morris
    Office of Genetics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS K 28, Atlanta, GA 30341 3724, USA
    Community Genet 6:22-8. 2003
    ..Diseases thought to be caused by exposure to environmental factors are also influenced by genetic susceptibility. It is not clear to what extent the public recognizes the role of genetics in causing these diseases...
  2. ncbi Genomics and public health at CDC
    Marta Gwinn
    National Office of Public Health Genomics, CDC, 4770 Buford Hwy, MS K 89, Atlanta, GA 30342, USA
    MMWR Morb Mortal Wkly Rep 55:20-1. 2006
    ....
  3. ncbi Invited commentary: genes, environment, and hybrid vigor
    Marta Gwinn
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Epidemiol 170:703-7. 2009
    ....
  4. ncbi Genomics and public health in the United States: signposts on the translation highway
    Marta Gwinn
    Office of Genomics and Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Community Genet 9:21-6. 2006
    ....
  5. ncbi Horizon scanning for new genomic tests
    Marta Gwinn
    McKing Consulting Corporation, Atlanta, Georgia, USA
    Genet Med 13:161-5. 2011
    ..Consequently, it is not easy to determine which tests are in development, currently available, or discontinued. We developed and assessed the usefulness of a systematic approach to identifying new genomic tests on the Internet...
  6. ncbi GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 9:205. 2008
    ..The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies...
  7. ncbi GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studies
    Wei Yu
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 19:1095-9. 2011
    ..hugenavigator.net/HuGENavigator/gWAHitStartPage.do). The GWAS Integrator may help enhance inference on potential genetic associations identified from GWAS studies...
  8. ncbi An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiology
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 8:436. 2007
    ..The design of this infrastructure makes the system potentially extensible to other data sources...
  9. ncbi Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment
    Ajay Yesupriya
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
    BMC Med Res Methodol 8:31. 2008
    ..Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies...
  10. ncbi HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 16:1155-8. 2008
    ..The application allows users to display temporal trends and spatial distributions as line charts and google maps, providing a quick overview of progress in the field. http://www.hugenavigator.net/HuGENavigator/startPageWatch.do..
  11. ncbi Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 9:528. 2008
    ..The application, called Gene Prospector, also provides a comprehensive set of links to additional data sources...
  12. ncbi Trends in population-based studies of human genetics in infectious diseases
    Jessica L Rowell
    Office of Public Health Genomics, Office of Epidemiology, Surveillance, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 7:e25431. 2012
    ..This approach offers new opportunities for understanding infectious disease susceptibility, severity, treatment, control, and prevention...
  13. ncbi An automatic method to generate domain-specific investigator networks using PubMed abstracts
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Inform Decis Mak 7:17. 2007
    ..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...
  14. ncbi Knowledge integration at the center of genomic medicine
    Muin J Khoury
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Genet Med 14:643-7. 2012
    ..The ultrarapid production of information requires adequate public and private resources for knowledge integration to support the evidence-based development of genomic medicine...
  15. ncbi Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey
    Quanhe Yang
    Division for Heart Diseases and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mail Stop K 47, Atlanta, GA 30341, USA
    Arch Intern Med 171:1183-91. 2011
    ..Few studies have examined joint effects of dietary sodium and potassium intake on risk of mortality...
  16. ncbi Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database
    Bruce K Lin
    Office of Genomics and Disease Prevention, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Epidemiol 164:1-4. 2006
    ..Here, the authors provide an overview of the database and its characteristics and uses...
  17. ncbi The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?
    Muin J Khoury
    National Office of Public Health Genomics Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Genet Med 9:665-74. 2007
    ..With continued advances in genomic applications, however, the full continuum of translation research needs adequate support to realize the promise of genomics for human health...
  18. ncbi Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases
    Muin J Khoury
    Office of Public Health Genomics, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Epidemiol 170:269-79. 2009
    ..As a next step in the evolution of Human Genome Epidemiology reviews, the authors invite investigators to submit field synopses for possible publication in the American Journal of Epidemiology...
  19. ncbi Genetic epidemiology with a capital E, ten years after
    Muin J Khoury
    Office of Public Health Genomics, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta GA 30333, USA
    Genet Epidemiol 35:845-52. 2011
    ..We extend Duncan Thomas' capital E to include "Evaluation" as the tools of epidemiology are increasingly used to assess how genome-based information can be applied in medicine and public health...
  20. ncbi Application of support vector machine modeling for prediction of common diseases: the case of diabetes and pre-diabetes
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Inform Decis Mak 10:16. 2010
    ..We illustrate the method to detect persons with diabetes and pre-diabetes in a cross-sectional representative sample of the U.S. population...
  21. ncbi On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies
    Muin J Khoury
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Int J Epidemiol 36:439-45. 2007
    ..Efforts by the Human Genome Epidemiology Network (HuGENet) are currently ongoing to streamline and operationalize these criteria for data on genetic associations with common diseases...
  22. ncbi Beyond base pairs to bedside: a population perspective on how genomics can improve health
    Muin J Khoury
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Public Health 102:34-7. 2012
    ....
  23. ncbi The need for genetic variant naming standards in published abstracts of human genetic association studies
    Wei Yu
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    BMC Res Notes 2:56. 2009
    ..The consistent use of rs numbers in abstracts that report genetic associations would enhance knowledge synthesis and translation in this field...
  24. ncbi The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop
    Muin J Khoury
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Genet Med 11:559-67. 2009
    ..To fulfill the promise of personal genomics, a rigorous multidisciplinary research agenda is needed...
  25. ncbi Will genomics widen or help heal the schism between medicine and public health?
    Muin J Khoury
    National Office of Public Health Genomics, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341, USA
    Am J Prev Med 33:310-7. 2007
    ..A strong medicine-public health partnership in the genomics era is needed for the translation of all scientific discoveries for the benefit of population health...
  26. ncbi The emergence of translational epidemiology: from scientific discovery to population health impact
    Muin J Khoury
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Epidemiol 172:517-24. 2010
    ..02). Epidemiology is increasingly recognized as an important component of TR. By quantifying and integrating knowledge across disciplines, epidemiology provides crucial methods and tools for TR...
  27. ncbi The emergence of epidemiology in the genomics age
    Muin J Khoury
    Office of Genomics and Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Int J Epidemiol 33:936-44. 2004
  28. ncbi An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions
    Muin J Khoury
    Office of Genomics and Disease Prevention, Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Genet Med 6:38-47. 2004
    ..CONCLUSION: To assess the value of genomic profiling, well-designed epidemiologic studies are needed to quantify disease risks, in addition to costs, benefits, and risks for testing and interventions...
  29. ncbi Unrecognized HIV infection among patients attending sexually transmitted disease clinics
    Hillard Weinstock
    Division of HIV AIDS Prevention, Surveillance and Epidemiology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Public Health 92:280-3. 2002
    ..This study examined voluntary HIV testing rates in sexually transmitted disease (STD) clinics...
  30. ncbi Age-specific seroprevalence of HIV, hepatitis B virus, and hepatitis C virus infection among injection drug users admitted to drug treatment in 6 US cities
    Christopher S Murrill
    Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, 1600 Clifton Road, Mail Stop E 46, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Public Health 92:385-7. 2002
    ..This study measured age-specific seroprevalence of HIV, hepatitis B virus, and hepatitis C virus (HCV) infection among injection drug users (IDUs) admitted to drug treatment programs in 6 US cities...
  31. ncbi HIV seroincidence among patients at clinics for sexually transmitted diseases in nine cities in the United States
    Hillard Weinstock
    Division of HIV AIDS Prevention Surveillance and Epidemiology, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E02, Atlanta, GA 30333, USA
    J Acquir Immune Defic Syndr 29:478-83. 2002
    ..Decreasing rates of new AIDS diagnoses in the 1990s do not reflect stable rates of new HIV infections among MSM and heterosexual patients attending these clinics...
  32. ncbi Steroid 5-{alpha}-reductase Type 2 (SRD5a2) gene polymorphisms and risk of prostate cancer: a HuGE review
    Jun Li
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K55, Atlanta, GA 30341, USA
    Am J Epidemiol 171:1-13. 2010
    ..Analysis of well-designed population-based studies with pathway-based arrays containing common genetic variants could be useful for identifying genetic factors in prostate cancer...
  33. ncbi Do we need genomic research for the prevention of common diseases with environmental causes?
    Muin J Khoury
    Office of Genomics and Disease Prevention, Coordinating Center on Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Epidemiol 161:799-805. 2005
    ..This research is likely to lead to population-wide health promotion and disease prevention efforts, not only to interventions targeted according to genetic susceptibility...
  34. ncbi Genome-wide association studies in pharmacogenomics: untapped potential for translation
    Idris Guessous
    Emory University, Rollins School of Public Health Department of Epidemiology, Grace Crum Rollins Building, 1518 Clifton Road, Atlanta, Georgia 30322, USA
    Genome Med 1:46. 2009
    ....
  35. ncbi Human genomics and preparedness for infectious threats
    Nicole F Dowling
    Office of Public Health Genomics, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Genome Med 1:119. 2009
    ..With rapid advances in laboratory technologies, banking and analysis of human genomic specimens can be conducted as part of public health investigations, enabling valuable research well into the future...
  36. ncbi Can family history be used as a tool for public health and preventive medicine?
    Paula W Yoon
    Office of Genomics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Genet Med 4:304-10. 2002
  37. ncbi Systems-based candidate genes for human response to influenza infection
    Lyna Zhang
    Office of Public Health Genomics, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Infect Genet Evol 9:1148-57. 2009
    ....
  38. ncbi Genomics, epidemiology, and common complex diseases: let's not throw out the baby with the bathwater!
    Muin J Khoury
    Int J Epidemiol 35:1363-4; author reply 1364-5. 2006
  39. ncbi Research priorities for public health sciences in the postgenomic era
    Marta Gwinn
    Genet Med 4:410-1. 2002
  40. ncbi The human genome project is complete. How do we develop a handle for the pump?
    Julian Little
    Am J Epidemiol 157:667-73. 2003
  41. ncbi A road map for efficient and reliable human genome epidemiology
    John P A Ioannidis
    Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology Hellas, Ioannina 45110, Greece
    Nat Genet 38:3-5. 2006
    ..Systematic reviews will be expanded to include more meta-analyses of individual-level data and prospective meta-analyses. Field synopses will offer regularly updated overviews...
  42. ncbi Does genetic testing really improve the prediction of future type 2 diabetes?
    A Cecile J W Janssens
    PLoS Med 3:e114; author reply e127. 2006
  43. ncbi Make it HuGE: human genome epidemiology reviews, population health, and the IJE
    George Davey Smith
    Int J Epidemiol 35:507-10. 2006
  44. ncbi Genomics and public health research
    Muin J Khoury
    JAMA 297:2347; author reply 2347-8. 2007
  45. ncbi Reporting of systematic reviews: the challenge of genetic association studies
    Muin J Khoury
    PLoS Med 4:e211. 2007
  46. ncbi Turning the pump handle: evolving methods for integrating the evidence on gene-disease association
    Julian P T Higgins
    Am J Epidemiol 166:863-6. 2007
  47. ncbi Use of the sensitive/less-sensitive (detuned) EIA strategy for targeting genetic analysis of HIV-1 to recently infected blood donors
    Daisy M Machado
    Blood Centers of the Pacific, San Francisco, California 94118, USA
    AIDS 16:113-9. 2002
    ....
  48. ncbi A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions
    A Cecile J W Janssens
    Department of Public Health, Erasmus MC University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Am J Hum Genet 82:593-9. 2008
    ..There is insufficient scientific evidence to conclude that genomic profiles are useful in measuring genetic risk for common diseases or in developing personalized diet and lifestyle recommendations for disease prevention...
  49. ncbi A navigator for human genome epidemiology
    Wei Yu
    Nat Genet 40:124-5. 2008
  50. ncbi Dermatology and the human genome: an epidemiologic approach
    Marta Gwinn
    Arch Dermatol 143:1194-6. 2007
  51. ncbi Family history assessment: strategies for prevention of cardiovascular disease
    Steven C Hunt
    Cardiovascular Genetics Research Program, Department of Internal Medicine, University of Utah School of Medicine, 410 Chipeta Way, Room 167, Salt Lake City, UT 84108, USA
    Am J Prev Med 24:136-42. 2003
    ..A positive family history also identifies the relatively small subset of families in the population at highest risk for CVD who may benefit most from targeted screening and intensive intervention...
  52. ncbi Predictive genetic testing for type 2 diabetes
    A Cecile J W Janssens
    BMJ 333:509-10. 2006
  53. ncbi Family history of heart disease and cardiovascular disease risk-reducing behaviors
    Margaret E McCusker
    , Bureau of Chronic Disease and Tobacco Prevention, 1100 West 49th Street, T-402, Austin, TX 78756, USA
    Genet Med 6:153-8. 2004
    ..Family history merits further investigation as a public health tool to identify persons with increased HD risk who might benefit from enhanced prevention strategies...
  54. ncbi Intention to analyze in pharmacogenomics studies
    Marta Gwinn
    Cancer Epidemiol Biomarkers Prev 17:740; author reply 740-1. 2008
  55. ncbi Five genetic variants associated with prostate cancer
    Ralph J Coates
    N Engl J Med 358:2738; author reply 2741. 2008
  56. ncbi Genetic test evaluation: information needs of clinicians, policy makers, and the public
    Wylie Burke
    University of Washington, Seattle, WA, USA
    Am J Epidemiol 156:311-8. 2002
    ....
  57. ncbi Expanded publishing model for genetic association studies
    Marta Gwinn
    Cancer Epidemiol Biomarkers Prev 15:185. 2006