Research Topics
| Roger I GlassSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Publications
Rotavirus vaccines: past, present, and futureR I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Mailstop GO4 CDC, 1600 Clifton Road, Atlanta, GA 30333, USA
Arch Pediatr 12:844-7. 2005
The value of cholera vaccines reassessedRoger I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Lancet 366:7-9. 2005
Epidemiological profile and burden of rotavirus diarrhea in Vietnam: 5 years of sentinel hospital surveillance, 1998-2003Nguyen Van Man
Poliomyelitis Vaccine Research and Production Center, Hanoi, Vietnam
J Infect Dis 192:S127-32. 2005..Study outcomes will provide information for future testing and potential use of a rotavirus vaccine...
Rotavirus vaccines: targeting the developing worldRoger I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:S160-6. 2005....
Development of candidate rotavirus vaccines derived from neonatal strains in IndiaRoger I Glass
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:S30-5. 2005..This unique project, which is developing a new rotavirus vaccine in India with the use of Indian strains, an Indian manufacturer, and an Indian clinical development program, aims to expedite introduction of rotavirus vaccines in India...
The future of rotavirus vaccines: a major setback leads to new opportunitiesRoger I Glass
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Lancet 363:1547-50. 2004
Estimates of the burden of rotavirus disease in MalaysiaVincent P Hsu
Respiratory and Enteric Virus Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:S80-6. 2005..We sought to estimate rotavirus disease-associated morbidity and mortality in Malaysia, using available sources of information...
Rotavirus vaccines: current prospects and future challengesRoger I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Lancet 368:323-32. 2006....
Detection and characterization of group C rotavirus in Buenos Aires, Argentina, 1997-2003Alejandro A Castello
Division of Viral Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia, USA
J Med Virol 81:1109-16. 2009..These findings indicate that RVC is a significant cause of diarrhea and it is necessary to develop simple and sensitive serological methods for its detection...
Isolation and characterization of a new simian rotavirus, YK-1Larry E Westerman
Viral Gastroenteritis Team, Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Virol J 3:40. 2006..A requirement for an effective animal model is the availability of appropriate rotavirus stocks for challenge...
Burden of rotavirus disease among children visiting pediatric emergency departments in Cincinnati, Ohio, and Oakland, California, in 1999-2000Eileen L Yee
Division of Viral Diseases, Epidemic Intelligence Service Program, Office of Workforce and Career Development, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 122:971-7. 2008..We assessed the incidence of rotavirus disease requiring an emergency department visit among children <5 years of age...
Cost-effectiveness and potential impact of rotavirus vaccination in the United StatesMarc Alain Widdowson
Respiratory and Enteric Virus Branch, Mailstop A34, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
Pediatrics 119:684-97. 2007..We assessed the health and economic impacts of a national rotavirus immunization program in the United States...
Rotavirus antigenemia in patients with acute gastroenteritisThea K Fischer
Viral Gastroenteritis Team, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA or
J Infect Dis 192:913-9. 2005..In situations in which stool samples are not readily available (i.e., patients with severe dehydration or those recently recovered or deceased), serum testing by enzyme immunoassay offers a new and practical diagnostic tool...
Molecular and epidemiologic trends of caliciviruses associated with outbreaks of acute gastroenteritis in the United States, 2000-2004Lenee H Blanton
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 193:413-21. 2006..The public health impact of caliciviruses will not be fully appreciated, nor will interventions be completely evaluated, until methods to detect these viruses are more routinely used...
Use of TaqMan real-time reverse transcription-PCR for rapid detection, quantification, and typing of norovirusA Angelica Trujillo
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 44:1405-12. 2006..These assays have proven useful in assisting scientists in public health and diagnostic laboratories report findings quickly to outbreak management teams...
Molecular epidemiology of genogroup II-genotype 4 noroviruses in the United States between 1994 and 2006Du Ping Zheng
Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 48:168-77. 2010..We propose that GII.4 subclusters be defined as having >5% sequence variation between strains. Our data confirm other studies on the rapid emergence and displacement of highly virulent GII.4 strains...
Update on rotavirus vaccinesJoseph S Bresee
Respiratory and Enteric Virus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 24:947-52. 2005..This update reviews the epidemiology of rotavirus infections, assesses past and current vaccines and presents ideas for implementation of vaccination programs in developed and developing countries...
United States rotavirus strain surveillance from 2005 to 2008: genotype prevalence before and after vaccine introductionJennifer J Hull
Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 30:S42-7. 2011..To monitor the distribution of rotavirus genotypes before and after vaccine introduction, the Centers for Disease Control and Prevention conducted strain surveillance with the National Rotavirus Strain Surveillance System...
Norovirus transmission on cruise shipElmira T Isakbaeva
Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Emerg Infect Dis 11:154-8. 2005..We documented transmission by food and person-to-person contact; persistence of virus despite sanitization onboard, including introductions of new strains; and seeding of an outbreak on land...
Global impact of rotavirus vaccinesJacqueline E Tate
National Center for Immunization and Respiratory Diseases, US CDC, 1600 Clifton Rd NE, MS A47, Atlanta, GA 30333, USA
Expert Rev Vaccines 9:395-407. 2010..e., herd protection). Early clinical trial data from Africa and Asia are promising, and further efforts are needed to optimize the benefits of vaccination in developing countries where vaccines are likely to have their greatest impact...
The epidemiology and burden of rotavirus in China: a review of the literature from 1983 to 2005Evan W Orenstein
Viral Gastroenteritis Section, CDC, Atlanta, GA, USA
Vaccine 25:406-13. 2007....
Characterization of VP6 genes from rotavirus strains collected in the United States from 1996-2002Tara K Kerin
National Center for Immunization and Respiratory Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, N E MS G 04, Atlanta, GA 30333, USA
Virus Genes 35:489-95. 2007....
Norovirus and child care: challenges in outbreak controlElmira T Isakbaeva
Epidemic Intelligence Service, Epidemiology Program Office, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 24:561-3. 2005..No breach of hygiene or contact with fecal matter was identified. Excluding the child with gastroenteritis from the playgroup could have prevented this outbreak...
Reevaluation of epidemiological criteria for identifying outbreaks of acute gastroenteritis due to norovirus: United States, 1998-2000Reina M Turcios
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 42:964-9. 2006....
Intussusception after administration of the rhesus tetravalent rotavirus vaccine (Rotashield): the search for a pathogenic mechanismMaureen Lynch
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 117:e827-32. 2006..The Peyer's patches were not hyperplastic, and we could not establish the pathogenic mechanism for this association...
Hospitalizations associated with rotavirus gastroenteritis in the United States, 1993-2002Myrna D Charles
Respiratory and Enteric Virus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 25:489-93. 2006..CONCLUSIONS: Rotavirus gastroenteritis remains an important cause of hospitalizations in the United States, and the rate has not declined from 1993 through 2002...
Detection of viral agents in fecal specimens of monkeys with diarrheaYuhuan Wang
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Emory University, Atlanta, GA, USA
J Med Primatol 36:101-7. 2007....
Importance and challenges of accurately counting rotavirus deaths in China, 2002Eileen L Yee
Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Epidemiology Branch, Atlanta, GA 30333, USA
Vaccine 27:F46-9. 2009..Thus, a national rotavirus immunization program targeting rural areas with high mortality from diarrhoea could dramatically reduce these deaths and urban areas could reduce childhood hospitalizations attributed to rotavirus by 43%...
Public health. Progress toward rotavirus vaccinesUmesh D Parashar
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Science 312:851-2. 2006
Norovirus and foodborne disease, United States, 1991-2000Marc-Alain Widdowson
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 11:95-102. 2005..More widespread use of molecular assays will permit better estimates of the role of NoV illness and help direct efforts to control foodborne illness...
Inactivated rotavirus vaccine induces protective immunity in gnotobiotic pigletsYuhuan Wang
Division of Viral Diseases, Centers for Diseases Control and Prevention, Atlanta, GA, USA
Vaccine 28:5432-6. 2010..Our findings demonstrate the proof of concept for an IRV in a large animal model and provide evidence and justification for further clinical development as an alternative candidate vaccine...
Use of active surveillance to validate international classification of diseases code estimates of rotavirus hospitalizations in childrenVincent P Hsu
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 115:78-82. 2005..Our study evaluated the sensitivity of the rotavirus ICD code among children hospitalized for AGE by using active surveillance for rotavirus at a tertiary children's hospital...
Novel human rotavirus genotype G5P[7] from child with diarrhea, CameroonMathew D Esona
Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 15:83-6. 2009..This G5P[7] strain exemplifies the importance of heterologous animal rotaviruses in generating HRV genetic diversity through reassortment...
Oral rotavirus vaccines: how well will they work where they are needed most?Manish Patel
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 200:S39-48. 2009....
Serum IgG mediates mucosal immunity against rotavirus infectionLarry E Westerman
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Proc Natl Acad Sci U S A 102:7268-73. 2005..The observation that passively transferred antibodies can suppress or delay viral infection in rotavirus-challenged pigtailed macaques has important implications for the design and testing of parenteral candidate rotavirus vaccines...
Molecular epidemiology of group A rotavirus diarrhea among children in Buenos Aires, Argentina, from 1999 to 2003 and emergence of the infrequent genotype G12A A Castello
Viral Gastroenteritis Team, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
J Clin Microbiol 44:2046-50. 2006..The finding of G12 strains in several other regions of the world raises the possibility that G12 may be emerging globally and suggests that surveillance for this strain should be conducted routinely...
Human caliciviruses as a cause of severe gastroenteritis in Peruvian childrenUmesh D Parashar
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
J Infect Dis 190:1088-92. 2004..49% [88/181]; P<.001). HuCVs appear to be an important cause of gastroenteritis in Peruvian children...
Rotavirus disease and its preventionMarc Alain Widdowson
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Curr Opin Gastroenterol 21:26-31. 2005....
Deaths from rotavirus disease in Bangladeshi children: estimates from hospital-based surveillanceGo Tanaka
Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
Pediatr Infect Dis J 26:1014-8. 2007..To assess the potential health benefits of introducing new rotavirus (RV) vaccines, we estimated mortality from RV gastroenteritis in Bangladeshi children <5 years of age...
Enhanced surveillance of norovirus outbreaks of gastroenteritis in GeorgiaMarc Alain Widdowson
National Center for Immunizations and Respiratory Disease, Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Public Health Rep 126:251-8. 2011..We conducted a prospective study in one state in which enhanced testing for noroviruses was performed to better understand the relative contribution of all gastroenteric pathogens...
Immunogenicity of a thermally inactivated rotavirus vaccine in miceBaoming Jiang
Gastroenteritis and Respiratory Virus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Hum Vaccin 4:143-7. 2008....
Rotavirus vaccination and intussusception: can we decrease temporally associated background cases of intussusception by restricting the vaccination schedule?Jennifer H Tai
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatrics 118:e258-64. 2006..Public health policy and education messages for physicians and parents should be developed to anticipate intussusception events that will occur by chance alone but are temporally related to rotavirus vaccination...
Health care costs of diarrheal disease and estimates of the cost-effectiveness of rotavirus vaccination in VietnamThea K Fischer
Division of Viral and Rickettsial Diseases and Epidemiology Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:1720-6. 2005..CONCLUSIONS: Vaccination can effectively reduce the disease burden and health care costs of rotavirus-specific diarrhea in Vietnam...
Inhibitory effect of breast milk on infectivity of live oral rotavirus vaccinesSung Sil Moon
National Centers for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 29:919-23. 2010..We assessed whether the neutralizing activity of breast milk could lower the titer of vaccine virus and explain this difference in vitro...
Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programsJon R Gentsch
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:S146-59. 2005..The enormous diversity and capacity of human rotaviruses for change suggest that rotavirus vaccines must provide good heterotypic protection to be optimally effective...
How much could rotavirus vaccines reduce diarrhea-associated mortality in northern Ghana? A model to assess impactMelissa L Arvay
Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia, USA
J Infect Dis 200:S85-91. 2009..We modeled vaccine impact on rotavirus-associated mortality in rural Ghana...
Characterization of nontypeable rotavirus strains from the United States: identification of a new rotavirus reassortant (P2A[6],G12) and rare P3[9] strains related to bovine rotavirusesD D Griffin
Viral Gastroenteritis Section, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, USA
Virology 294:256-69. 2002....
Are noroviruses emerging?Marc-Alain Widdowson
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 11:735-7. 2005
The epidemiology of rotavirus diarrhea in Latin America. Anticipating rotavirus vaccinesErin M Kane
Viral Gastroenteritis Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Rev Panam Salud Publica 16:371-7. 2004..Data from surveillance studies will be critical to monitor the impact of the future introduction of vaccines...
Global illness and deaths caused by rotavirus disease in childrenUmesh D Parashar
Viral Gastroenteritis Section, Division of Viral and Ricksettial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop G04, Atlanta, GA 30333, USA
Emerg Infect Dis 9:565-72. 2003..The tremendous incidence of rotavirus disease underscores the urgent need for interventions, such as vaccines, particularly to prevent childhood deaths in developing nations...
Broadening the age restriction for initiating rotavirus vaccination in regions with high rotavirus mortality: benefits of mortality reduction versus risk of fatal intussusceptionManish M Patel
National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Vaccine 27:2916-22. 2009..This policy could exclude a substantial number of children from vaccination, especially in developing countries where delays in vaccination are common...
The burden of rotavirus diarrhea in Khanh Hoa Province, Vietnam: baseline assessment for a rotavirus vaccine trialDang Duc Anh
National Institute for Hygiene and Epidemiology, Hanoi, Vietnam
Pediatr Infect Dis J 25:37-40. 2006..We found the epidemiologic features of rotavirus in rural Vietnam to be more similar to those of rotavirus in a developed country than to those of rotavirus in India or Bangladesh...
Experimental infection of pigtailed macaques with a simian rotavirus, YK-1Larry E Westerman
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Emory University, Atlanta, GA 30333, USA
J Med Virol 75:616-25. 2005....
Routine laboratory testing data for surveillance of rotavirus hospitalizations to evaluate the impact of vaccinationManish M Patel
Centers for Disease Control and Prevention, National Center for Immunizations and Respiratory Diseases, Atlanta, GA 30329, USA
Pediatr Infect Dis J 26:914-9. 2007..We examined laboratory and hospital discharge data for 2 tertiary care pediatric hospitals to assess the utility of routine laboratory testing data for surveillance of rotavirus gastroenteritis and to estimate rotavirus disease burden...
Foodborne viral gastroenteritis: challenges and opportunitiesJoseph S Bresee
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
Clin Infect Dis 35:748-53. 2002..Implementation of simple prevention measures, including correct food-handling practices, will continue to be a priority...
Norovirus classification and proposed strain nomenclatureDu Ping Zheng
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 346:312-23. 2006..Of these, five clusters in G2 and one in G1 are newly described. This analysis can serve as the basis for a standardized nomenclature to genetically describe NoV strains...
Systematic literature review of role of noroviruses in sporadic gastroenteritisManish M Patel
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 14:1224-31. 2008....
Projected Impact of the new rotavirus vaccination program on hospitalizations for gastroenteritis and rotavirus disease among US children <5 years of age during 2006-2015Aaron T Curns
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
J Infect Dis 200:S49-56. 2009..We forecasted the potential reduction in the number of hospitalizations for rotavirus disease and AGE in US children during 2006-2015 as a result of the new rotavirus vaccine introduced in 2006...
Prevalence of rotavirus and norovirus antibodies in non-human primatesBaoming Jiang
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
J Med Primatol 33:30-3. 2004..Given the high rate of infection with both viruses, the role of these agents in causing acute gastroenteritis in non-human primates and the value of these animals as models of infection and disease need to be assessed...
Diarrhea- and rotavirus-associated hospitalizations among children less than 5 years of age: United States, 1997 and 2000Mark A Malek
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatrics 117:1887-92. 2006..Estimates of the burden of severe rotavirus disease, particularly hospitalizations, will help evaluate the potential benefits of a national rotavirus immunization program...
Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus--United States, 2002Marc Alain Widdowson
Atlanta Research and Education Foundation and National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 190:27-36. 2004..Control measures for outbreaks should address all routes of transmission. Better outbreak surveillance and collection of data on sequences will help to monitor norovirus strains and to identify common sources...
Epidemiologic and molecular trends of "Norwalk-like viruses" associated with outbreaks of gastroenteritis in the United StatesRebecca L Fankhauser
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 186:1-7. 2002..Strain diversity was great: one potential new sequence cluster was implicated in multiple outbreaks, and strains belonging to a tentative new genogroup were identified...
Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunizationN A Cunliffe
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA, USA
Bull World Health Organ 76:525-37. 1998..Wherever large numbers of cases of rotavirus diarrhoea occur early in infancy, immunization at birth may protect the children before their first symptomatic infection...
Molecular characterization of serotype G9 rotavirus strains from a global collectionM Ramachandran
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Virology 278:436-44. 2000..S. G9 progenitors. Overall, our findings suggest that much greater diversity among the newly identified G9 strains has been generated by reassortment between gene segments than through the accumulation of mutations in a single gene...
Rotavirus and severe childhood diarrheaUmesh D Parashar
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 12:304-6. 2006..Application of this proportion to the recent World Health Organization estimates of diarrhea-related childhood deaths gave an estimated 611,000 (range 454,000-705,000) rotavirus-related deaths...
Rotavirus in Asia: the value of surveillance for informing decisions about the introduction of new vaccinesJoseph S Bresee
Viral Gastroenteritis Section, Respiratory and Enteric Virus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 192:S1-5. 2005
New hope for defeating rotavirusRoger I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, USA
Sci Am 294:46-51, 54-5. 2006
Comparing serologic response against enteric pathogens with reported diarrhea to assess the impact of improved household drinking water qualityJohn A Crump
Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 77:136-41. 2007..Larger intervention studies that yield a more marked effect on diarrheal disease, use additional and improved serologic assays, and that collect serum samples at more frequent intervals are needed...
A waterborne outbreak of Norwalk-like virus among snowmobilers-Wyoming, 2001Alicia D Anderson
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 187:303-6. 2003..This multistrain NLV outbreak investigation illustrates the importance of NLV as a cause of waterborne illness and should encourage monitoring for NLVs in drinking water...
The epidemiology and disease burden of rotavirus in Vietnam: sentinel surveillance at 6 hospitalsV M Nguyen
Poliomyelitis Vaccine Research and Production Center, Hanoi, Vietnam
J Infect Dis 183:1707-12. 2001..Thus, the disease burden of rotavirus in Vietnam is substantial, and programs to encourage the use of oral rehydration should be encouraged while efforts to develop vaccines continue...
Characterization of serotype G9 rotavirus strains isolated in the United States and India from 1993 to 2001A R Laird
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:3100-11. 2003....
Outbreaks of adult gastroenteritis traced to a single genotype of rotavirusDixie D Griffin
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 185:1502-5. 2002..For the rotavirus vaccines under development, special attention may need to be paid to protection against G2 strains...
Six-year retrospective surveillance of gastroenteritis viruses identified at ten electron microscopy centers in the United States and CanadaJ F Lew
Viral Gastroenteritis Unit, Centers for Disease Control, United States Department of Health and Human Services, Atlanta, GA 30333
Pediatr Infect Dis J 9:709-14. 1990..Because of the relative insensitivity of direct electron microscopy as a screening method for SRVs, astroviruses and caliciviruses, these data probably underestimate the true prevalence of disease caused by these agents...
Unexpected detection of animal VP7 genes among common rotavirus strains isolated from children in MexicoA R Laird
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:4400-3. 2003....
Characterization of capsid genes, expressed in the baculovirus system, of three new genetically distinct strains of "Norwalk-like viruses"G Belliot
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 39:4288-95. 2001....
Epidemiology of rotavirus in IndiaV Jain
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Indian J Pediatr 68:855-62. 2001....
Prevention of rotavirus gastroenteritis among infants and children. Recommendations of the Advisory Committee on Immunization Practices (ACIP)Umesh D Parashar
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC, 1600 Clifton Rd, NE MS A 34, Atlanta, GA 30333, USA
MMWR Recomm Rep 55:1-13. 2006..Rotavirus vaccine can be co-administered with other childhood vaccines. Rotavirus vaccine is contraindicated for infants with a serious allergic reaction to any vaccine component or to a previous dose of vaccine...
Diarrhea-associated hospitalizations and outpatient visits among American Indian and Alaska Native children younger than five years of age, 2000-2004Rosalyn J Singleton
Alaska Native Tribal Health Consortium, Anchorage, AK, USA
Pediatr Infect Dis J 26:1006-13. 2007..S. population of children, although diarrhea-associated hospitalization rates have declined among AI/AN children...
Temporal and geographic trends of rotavirus activity in the United States, 1997-2004Reina M Turcios
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatr Infect Dis J 25:451-4. 2006..NRVESS permits a gross assessment of RV geographic and temporal trends in the United States, but underscores the need for additional assessment mechanisms...
Rotavirus vaccines and the prevention of hospital-acquired diarrhea in childrenThea K Fischer
Epidemic Intelligence Service, Epidemiology Program Office, USA
Vaccine 22:S49-54. 2004..Development of safe and effective rotavirus vaccines will protect children worldwide against the severe consequences of rotavirus infections including prolonged hospitalizations for nosocomially acquired infections...
Rotavirus vaccination in Europe: the time has finally arrivedUmesh D Parashar
Epidemiology Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Pediatr Gastroenterol Nutr 46:S21-3. 2008
The epidemiology of rotavirus diarrhea in countries in the Eastern Mediterranean RegionMark A Malek
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 202:S12-22. 2010..Safe, effective rotavirus vaccines will be available soon, and accurate disease burden data will be needed to assess the burden of rotavirus and the value of new vaccines and monitor vaccine program impact...
The role of serum antibodies in the protection against rotavirus disease: an overviewBaoming Jiang
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 34:1351-61. 2002....
Global mortality associated with rotavirus disease among children in 2004Umesh D Parashar
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 200:S9-S15. 2009....
Rotavirus strain surveillance in Latin America: a review of the last nine yearsAlejandro A Castello
Viral Gastroenteritis Team, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
Pediatr Infect Dis J 23:S168-72. 2004....
Use of state hospital discharge data to assess the morbidity from rotavirus diarrhea and to monitor the impact of a rotavirus immunization program: A pilot study in ConnecticutU D Parashar
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 104:489-94. 1999..In a pilot study, we have assessed the usefulness of state hospital discharge data on diarrhea in children to provide this information by examining data from Connecticut...
Sequence analysis of the NSP4 gene from human rotavirus strains isolated in the United StatesC D Kirkwood
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
Virus Genes 19:113-22. 1999..Northern hybridization analysis with NSP4A and NSP4B total gene probes failed to detect any unusual combinations of the VP6 and NSP4 genes in 31 additional isolates from the 1996-1997 rotavirus season...
Genomic characterization of human rotavirus G8 strains from the African rotavirus network: relationship to animal rotavirusesM D Esona
Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, NCIRD, CDC, Atlanta, Georgia 30333, USA
J Med Virol 81:937-51. 2009..Although these findings help elucidate rotavirus evolution, sequence studies of cognate animal rotavirus genes are needed to conclusively determine the specific origin of those genes relative to both human and animal rotavirus strains...
Global seasonality of rotavirus infectionsS M Cook
Viral Gastroenteritis Unit, Centers for Disease Control, Atlanta, GA 30333
Bull World Health Organ 68:171-7. 1990....
The epidemiology of enteric caliciviruses from humans: a reassessment using new diagnosticsR I Glass
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 181:S254-61. 2000....
Correlation of patient immune responses with genetically characterized small round-structured viruses involved in outbreaks of nonbacterial acute gastroenteritis in the United States, 1990 to 1995J S Noel
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Med Virol 53:372-83. 1997....
Identification of a distinct common strain of "Norwalk-like viruses" having a global distributionJ S Noel
Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 179:1334-44. 1999....
Genetic and antigenic characterization of a serotype P[6]G9 human rotavirus strain isolated in the United StatesC D Kirkwood
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Atlanta, Georgia 30333, USA
Virology 256:45-53. 1999..Examination of historic collections and prospective surveillance of strains will be needed to determine whether this strain has been present for some time or if it is emerging to compete with the other common serotypes of rotavirus...
A one-tube method of reverse transcription-PCR to efficiently amplify a 3-kilobase region from the RNA polymerase gene to the poly(A) tail of small round-structured viruses (Norwalk-like viruses)T Ando
Viral Gastroenteritis Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 35:570-7. 1997..Because SRSVs have not yet been cultivated in vitro, this novel method should facilitate molecular characterization of SRSVs to provide a firm scientific foundation for improvements and refinements of SRSV diagnostics...
Hospitalizations associated with rotavirus diarrhea in the United States, 1993 through 1995: surveillance based on the new ICD-9-CM rotavirus-specific diagnostic codeU D Parashar
Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 177:13-7. 1998....
Lack of maternal antibodies to P serotypes may predispose neonates to infections with unusual rotavirus strainsM Ramachandran
Department of Pediatric Gastroenterology, All India Institute of Medical Sciences, New Delhi
Clin Diagn Lab Immunol 5:527-30. 1998....
Phylogenetic analysis of novel G12 rotaviruses in the United States: A molecular search for the origin of a new strainM M Freeman
Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Med Virol 81:736-46. 2009..Classifying rotavirus strains based only on VP7 (G) and VP4 (P) genotype potentially underestimates diversity and sequence analysis of the other segments is required to assess the complete genetic relationships between strains...
Epidemiology of diarrheal disease among children enrolled in four West Coast health maintenance organizations. Vaccine Safety Datalink TeamU D Parashar
Epidemic Intelligence Service, Viral Gastroenteritis Section, CDC, Atlanta, GA 30333, USA
Pediatr Infect Dis J 17:605-11. 1998..We used information from the Vaccine Safety Datalink (VSD) about approximately 1 million children enrolled in four health maintenance organizations to assess the morbidity from diarrhea and estimate the disease burden of rotavirus...
RotavirusU D Parashar
Viral Gastroenteritis Section, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Emerg Infect Dis 4:561-70. 1998..S. Food and Drug Administration on August 31, 1998, and should be cost-effective in reducing diarrheal diseases in industrialized countries. The vaccine's efficacy and cost-effectiveness in developing countries should be evaluated...
Surveillance of rotavirus strains in the United States: identification of unusual strains. The National Rotavirus Strain Surveillance System collaborating laboratoriesD D Griffin
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 38:2784-7. 2000..Other uncommon strains exist in the United States but may have been overlooked before because of their low prevalence and the use of inadequate diagnostic tools...
Trends in intussusception-associated hospitalizations and deaths among US infantsU D Parashar
Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia, USA
Pediatrics 106:1413-21. 2000..The newly licensed tetravalent rhesus-human reassortant rotavirus vaccine has been withdrawn following reports of intussusception among vaccinated infants...
