Research Topics
| S K FridkinSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Publications
Epidemiological and microbiological characterization of infections caused by Staphylococcus aureus with reduced susceptibility to vancomycin, United States, 1997-2001Scott K Fridkin
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 36:429-39. 2003..Independent risk factors for being a case patient included antecedent vancomycin use and prior oxacillin-resistant S. aureus infection 2 or 3 months before the current infection...- Methicillin-resistant Staphylococcus aureus disease in three communitiesScott K Fridkin
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 352:1436-44. 2005..Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. The national burden and clinical effect of this novel presentation of MRSA disease are unclear... - Routine cycling of antimicrobial agents as an infection-control measureScott K Fridkin
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
Clin Infect Dis 36:1438-44. 2003..However, optimizing antimicrobial use through traditional and novel methods (e.g., computer decision support) should not be abandoned... - The changing face of fungal infections in health care settingsScott K Fridkin
Mycotic Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 41:1455-60. 2005..In this context, the changing pathogen profiles, unique antifungal susceptibilities, and approaches to treatment are outlined... - Monitoring antimicrobial use and resistance: comparison with a national benchmark on reducing vancomycin use and vancomycin-resistant enterococciScott K Fridkin
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 8:702-7. 2002..5% compared with mean increase of 5.7%, p<0.001). In this study, practice changes focused towards specific ICUs were associated with decreases in ICU vancomycin use and VRE prevalence... - Temporal changes in prevalence of antimicrobial resistance in 23 US hospitalsScott K Fridkin
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 8:697-701. 2002..The increases seen are of concern; differences in factors present outside ICUs, such as excessive quinolone use or inadequate infection-control practices, may explain the observed trends... - The effect of vancomycin and third-generation cephalosporins on prevalence of vancomycin-resistant enterococci in 126 U.S. adult intensive care unitsS K Fridkin
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, MS A 35, 1600 Clifton Road, Atlanta, GA 30333, USA
Ann Intern Med 135:175-83. 2001..Identifying modifiable institutional factors can advance quality-improvement efforts to minimize hospital-acquired infections with VRE... - Antimicrobial resistance prevalence rates in hospital antibiograms reflect prevalence rates among pathogens associated with hospital-acquired infectionsS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 33:324-30. 2001..Hospital antibiograms may underestimate the relative frequency of methicillin resistance among Staphylococcus species when associated with hospital-acquired infections... - Surveillance of antimicrobial use and antimicrobial resistance in United States hospitals: project ICARE phase 2. Project Intensive Care Antimicrobial Resistance Epidemiology (ICARE) hospitalsS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 29:245-52. 1999..These comparative data on use and resistance among similar areas (i.e., ICU or other inpatient areas) can be used as a benchmark by participating hospitals to focus their efforts at addressing antimicrobial resistance... - Antimicrobial resistance in intensive care unitsS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Chest Med 20:303-16, viii. 1999..e., patient isolation, hand washing, glove use, and appropriate gown use), and implementation of a systematic review of antimicrobial use... - Vancomycin-intermediate and -resistant Staphylococcus aureus: what the infectious disease specialist needs to knowS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Clin Infect Dis 32:108-15. 2001..aureus are likely to be encountered... - Determinants of vancomycin use in adult intensive care units in 41 United States hospitalsS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 28:1119-25. 1999..Efforts to reduce these rates through infection control activities should be included in hospitals' efforts to reduce vancomycin use... - Ability of laboratories to detect emerging antimicrobial resistance in nosocomial pathogens: a survey of project ICARE laboratoriesC D Steward
Hospital Infections Program, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE G08 Atlanta, GA 30333, USA
Diagn Microbiol Infect Dis 38:59-67. 2000..This highlights the need for monitoring how well susceptibility test systems in clinical laboratories detect emerging resistance... - Outbreak of bloodstream infection with the mold Phialemonium among patients receiving dialysis at a hemodialysis unitThomas Clark
Epidemic Intelligence Service, Office of Workforce and Career Development, Atlanta, GA, USA
Infect Control Hosp Epidemiol 27:1164-70. 2006..Recovery of this mold from blood culture should be considered indicative of infection until proven otherwise. Furthermore, an investigation into possible healthcare-related environmental reservoirs should be considered... - Determining risk factors for candidemia among newborn infants from population-based surveillance: Baltimore, Maryland, 1998-2000Sharmila S Shetty
Mycotic Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 24:601-4. 2005..This study helps define a subgroup of preterm infants at high risk of developing bloodstream infections with Candida species... - Vancomycin-intermediate Staphylococcus aureus in a home health-care patientJ C Hageman
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 7:1023-5. 2001..The patient was treated successfully with antimicrobial therapy, biliary drainage, and reconstruction. Standard precautions in the home health setting appear successful in preventing transmission... - NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007Alicia I Hidron
Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA
Infect Control Hosp Epidemiol 29:996-1011. 2008.... - Nosocomial acquisition of Pseudomonas aeruginosa resistant to both ciprofloxacin and imipenem: a risk factor and laboratory analysisM R Mueller
Rollins School of Public Health, Emory University, Atlanta, GA, USA
Eur J Clin Microbiol Infect Dis 27:565-70. 2008..Fluoroquinolone use was not a risk factor for acquisitions of dually resistant P. aeruginosa. The absence of OprN in these isolates suggests that dual resistance is not due to mexT mutations... - Increasing prevalence of antimicrobial resistance in intensive care unitsS K Fridkin
Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Crit Care Med 29:N64-8. 2001..Crit Care Med 2001; 29[Suppl.]: N64-N68).. - Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999W E Trick
Health Outcomes Branch, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
Clin Infect Dis 35:627-30. 2002..During the study period, there was a significant decrease in the incidence of C. albicans BSI (P<.001) and a significant increase in the incidence of Candida glabrata BSI (P=.05)... - Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United StatesJ A Jernigan
NCID, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 7:933-44. 2001..With multidrug antibiotic regimens and supportive care, survival of patients (60%) was markedly higher (<15%) than previously reported... - Multistate outbreak of Fusarium keratitis associated with use of a contact lens solutionDouglas C Chang
Mycotic Diseases Branch, Career Development Division, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA, USA
JAMA 296:953-63. 2006..Beginning in March 2006, the Centers for Disease Control and Prevention received multiple reports of Fusarium keratitis among contact lens wearers... - Evaluation of amphotericin B interpretive breakpoints for Candida bloodstream isolates by correlation with therapeutic outcomeBenjamin J Park
Mycotic Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, N E, Mailstop C 09, Atlanta, GA 30333, USA
Antimicrob Agents Chemother 50:1287-92. 2006..06 to 2 microg/ml, respectively). Etest produced the widest distribution of MICs (0.094 to 2 microg/ml). However, none of the test formats studied generated results that significantly correlated with therapeutic success or failure... - Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002Matthew J Kuehnert
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 193:172-9. 2006..Although methicillin-resistant S. aureus (MRSA) infection has become increasingly reported, population-based S. aureus and MRSA colonization estimates are lacking... - Implications of detecting the mold Syncephalastrum in clinical specimens of New Orleans residents after Hurricanes Katrina and RitaCarol Y Rao
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Occup Environ Med 49:411-6. 2007..Only one patient reported significant exposure to mold (working on mold remediation without wearing a respirator) on the day of his incident culture... - Invasive methicillin-resistant Staphylococcus aureus infections in the United StatesR Monina Klevens
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
JAMA 298:1763-71. 2007..As the epidemiology of infections with methicillin-resistant Staphylococcus aureus (MRSA) changes, accurate information on the scope and magnitude of MRSA infections in the US population is needed... - Recommendations for metrics for multidrug-resistant organisms in healthcare settings: SHEA/HICPAC Position paper Adam L Cohen
Divisions of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Infect Control Hosp Epidemiol 29:901-13. 2008 - Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factorsR Monina Klevens
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 12:1991-3. 2006..Of patients with HRFs, 18%-28% had a "community-associated" strain, primarily USA300; of patients without HRFs, 26% had a "healthcare-associated" strain, typically USA100... - Methicillin-resistant Staphylococcus aureus central line-associated bloodstream infections in US intensive care units, 1997-2007Deron C Burton
Surveillance Branch, Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 301:727-36. 2009..Concerns about rates of methicillin-resistant Staphylococcus aureus (MRSA) health care-associated infections have prompted calls for mandatory screening or reporting in efforts to reduce MRSA infections... - Characterization of methicillin-resistant Staphylococcus aureus isolates collected in 2005 and 2006 from patients with invasive disease: a population-based analysisBrandi Limbago
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Clin Microbiol 47:1344-51. 2009..6%), in addition to beta-lactam agents. This collection provides a reference collection of MRSA isolates associated with invasive disease, collected in 2005 and 2006 in the United States, for future comparison and ongoing studies... - Contaminated product water as the source of Phialemonium curvatum bloodstream infection among patients undergoing hemodialysisCarol Y Rao
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Infect Control Hosp Epidemiol 30:840-7. 2009..We investigated a cluster of cases of bloodstream infection (BSI) due to the mold Phialemonium at a hemodialysis center in Illinois and conducted a cohort study to identify risk factors... - Health care-associated invasive MRSA infections, 2005-2008Alexander J Kallen
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
JAMA 304:641-8. 2010..Whether there have been changes in MRSA infection incidence as these programs become established is unknown; however, recent data have shown that rates of MRSA bloodstream infections (BSIs) in intensive care units are decreasing... - Trends in incidence of late-onset methicillin-resistant Staphylococcus aureus infection in neonatal intensive care units: data from the National Nosocomial Infections Surveillance System, 1995-2004Fernanda C Lessa
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 28:577-81. 2009..We assessed the scope and magnitude of MRSA infections with disease onset after 3 days of age (late-onset MRSA infections) in NICUs... - Epidemiologic and molecular characterization of an outbreak of Candida parapsilosis bloodstream infections in a community hospitalThomas A Clark
Epidemic Intelligence Service, Epidemiology Program Office, Division of Applied Public Health Training, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 42:4468-72. 2004..parapsilosis bloodstream infections in adults resulted from an interplay of host, environment, and pathogen factors. Recommendations for control measures focused on improving hand hygiene compliance... - Drug-resistant Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus surveillanceLeigh Ann Hawley
Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop C23, Atlanta, GA 30333, USA
Emerg Infect Dis 9:1358-9. 2003 - Evaluation of the NCCLS extended-spectrum beta-lactamase confirmation methods for Escherichia coli with isolates collected during Project ICAREFred C Tenover
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:3142-6. 2003..NCCLS has incorporated this change in the cefpodoxime screening breakpoint in its recent documents... - Changing incidence of Candida bloodstream infections among NICU patients in the United States: 1995-2004Scott K Fridkin
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
Pediatrics 117:1680-7. 2006..We evaluated the annual incidence of neonatal candidemia and the frequency of disease caused by different species of Candida among neonates in the United States... - No evidence of a mild form of inhalational Bacillus anthracis infection during a bioterrorism-related inhalational anthrax outbreak in Washington, D.C., in 2001Henry C Baggett
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, USA
Clin Infect Dis 41:991-7. 2005..anthracis infection. We hypothesized that early antibiotic use could have decreased the sensitivity of diagnostic tests or that bioterrorism-related inhalational anthrax may include mild disease... - Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance geneSoju Chang
Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta 30333, USA
N Engl J Med 348:1342-7. 2003 - Outbreak of cutaneous Rhizopus arrhizus infection associated with karaya ostomy bagsMysheika LeMaile-Williams
Epidemic Intelligence Service, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333 USA
Clin Infect Dis 43:e83-8. 2006..We investigated an outbreak involving 2 patients hospitalized at hospital A with cutaneous Rhizopus arrhizus (oryzae) infections of surgically created stomas... - Evaluating the potential public health impact of a Staphylococcus aureus vaccine through use of population-based surveillance for invasive methicillin-resistant S. aureus disease in the United StatesCynthia A Lucero
Centers for Disease Control and Prevention, NE, Atlanta, GA 30333, United States
Vaccine 27:5061-8. 2009..aureus vaccine could result in substantial reductions in invasive MRSA disease incidence. As candidate vaccines are evaluated, these data will be important in determining the optimal vaccination strategy... - Incidence of invasive aspergillosis following hematopoietic stem cell and solid organ transplantation: interim results of a prospective multicenter surveillance programJ Morgan
Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Med Mycol 43:S49-58. 2005..Our CI figures are lower compared to those of previous reports. The reasons for this are unclear, but may be related to changes in transplantation practices, diagnostic methods, and supportive care... - Status of tuberculosis infection control programs at United States hospitals, 1989 to 1992. APIC. Association for Professionals in Infection Control and EpidemiologyR L Sinkowitz
Hospital Infections Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Infect Control 24:226-34. 1996.... - Antimicrobial proficiency testing of National Nosocomial Infections Surveillance System hospital laboratoriesJeffrey C Hageman
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Infect Control Hosp Epidemiol 24:356-61. 2003..Disk diffusion continues to be unreliable for vancomycin testing of staphylococci and must be used cautiously for enterococci. Further education on the processing of ESbetaL-producing organisms is warranted... - Outcomes among inmates treated for coccidioidomycosis at a correctional institution during a community outbreak, Kern County, California, 2004Lauren A Burwell
Epidemic Intelligence Service, Office of Workforce and Career Development, and Mycotic Diseases Branch, Division of Foodborne, Bacterial, and Mycotic Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 49:e113-9. 2009..In response to an increase of coccidioidomycosis at a correctional institution in an endemic area, physicians initiated an enhanced diagnosis and treatment program... - Antifungal prophylaxis to prevent neonatal candidiasis: a survey of perinatal physician practicesLauren A Burwell
Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 118:e1019-26. 2006..The extent of antifungal prophylaxis use to prevent neonatal candidemia is unknown... - Emergence of community-associated methicillin-resistant Staphylococcus aureus at a Memphis, Tennessee Children's HospitalSteven C Buckingham
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
Pediatr Infect Dis J 23:619-24. 2004..CONCLUSIONS: Community-associated MRSA has emerged as a potentially invasive pathogen among children in the greater Memphis area, and this phenomenon is not explained by spread of nosocomial strains into the community... - The epidemiology of vancomycin-resistant Enterococcus colonization in a medical intensive care unitDavid K Warren
Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Infect Control Hosp Epidemiol 24:257-63. 2003..This was likely due in large part to prior VRE exposures in the rest of the hospital where these control measures were not being used... - More challenges in the prevention and management of community-associated, methicillin-resistant Staphylococcus aureus skin diseaseRachel Gorwitz
Ann Intern Med 148:310-2. 2008 - Cycling empirical antimicrobial agents to prevent emergence of antimicrobial-resistant Gram-negative bacteria among intensive care unit patientsDavid K Warren
Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
Crit Care Med 32:2450-6. 2004..To determine the impact of the rotation of antimicrobial agents on the rates of infection, intestinal colonization, and acquisition with antimicrobial-resistant Gram-negative bacteria... - Excess costs of hospital care associated with neonatal candidemiaP Brian Smith
Department of Pediatrics, 3179 Duke University Medical Center, Durham NC, 27710, USA
Pediatr Infect Dis J 26:197-200. 2007..Candida is an increasingly important nosocomial pathogen within intensive care nurseries. The purpose of this study was to determine the attributable cost of candidemia in neonates... - Management of inpatients colonized or infected with antimicrobial-resistant bacteria in hospitals in the United StatesRebecca H Sunenshine
Division of Infectious Diseases, Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA
Infect Control Hosp Epidemiol 26:138-43. 2005..In contrast, infectious diseases consultants are divided about the role of routine surveillance cultures in multidrug-resistant organism management, and few work in hospitals that use them... - Epidemiology and predictors of mortality in cases of Candida bloodstream infection: results from population-based surveillance, barcelona, Spain, from 2002 to 2003Benito Almirante
Infectious Diseases Division, Hospital Universitari Vall d Hebron, Avda Vall d Hebron, 119 129, 08035 Barcelona, Spain
J Clin Microbiol 43:1829-35. 2005..Antifungal medication and catheter removal are critical in preventing mortality... - The impact of an antibiotic cycling program on empirical therapy for gram-negative infectionsLiana R Merz
Division of Infectious Diseases, Washington University School of Medicine, Box 8051, 660 S Euclid Ave, Saint Louis, MO 63110, USA
Chest 130:1672-8. 2006..Therapy cycling empiric antibiotics between various classes may influence bacterial resistance patterns. Understanding the impact of cycling on the appropriate treatment of suspected Gram-negative infections is important... - Epidemiology of community-onset candidemia in Connecticut and MarylandAndre N Sofair
Yale University School of Medicine, New Haven, Connecticut, USA
Clin Infect Dis 43:32-9. 2006..CONCLUSION: We report that community-onset candidemia is common and occurs in patients with extensive contact with the health care system. Disease caused by C. parapsilosis tends to involve unique strains... - Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposureCynthia J Whitener
The Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
Clin Infect Dis 38:1049-55. 2004..For clinical and public health reasons, it is essential that microbiology laboratories adequately test for vancomycin-resistance in S. aureus... - Candidemia is costly--plain and simpleScott K Fridkin
Clin Infect Dis 41:1240-1. 2005