Research Topics
Species | Aaron ErdelySummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
|
Detail Information
Publications
Lung tumor production and tissue metal distribution after exposure to manual metal ARC-stainless steel welding fume in A/J and C57BL/6J micePatti C Zeidler-Erdely
Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Road M S L2015, Morgantown, WV 26505, USA
J Toxicol Environ Health A 74:728-36. 2011..In addition, long-term extrapulmonary tissue alterations in metals in the susceptible A/J mouse suggest that the adverse effects of this fume might be cumulative...- Short-term inhalation of stainless steel welding fume causes sustained lung toxicity but no tumorigenesis in lung tumor susceptible A/J micePatti C Zeidler-Erdely
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, WV 26505, USA
Inhal Toxicol 23:112-20. 2011..Under our exposure conditions, GMA-SS exposure resulted in no significant tumor development in A/J mice... - Inhalation exposure of gas-metal arc stainless steel welding fume increased atherosclerotic lesions in apolipoprotein E knockout miceAaron Erdely
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 2888, United States
Toxicol Lett 204:12-6. 2011..These results complement epidemiological and functional human studies that suggest welding may result in adverse cardiovascular effects... - Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matterAaron Erdely
Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505 2888, United States
Toxicology 287:153-9. 2011..In conclusion, varying types of welding fumes elicit quantitatively different systemic inflammatory and/or stress responses... - Identification of systemic markers from a pulmonary carbon nanotube exposureAaron Erdely
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
J Occup Environ Med 53:S80-6. 2011..Interest exists for early monitoring of worker exposure to engineered nanomaterials. Here, we highlight quantitative systemic markers of early effects after carbon nanotube (CNT) exposure... 
Type I interferon and pattern recognition receptor signaling following particulate matter inhalationAaron Erdely
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
Part Fibre Toxicol 9:25. 2012..Whole blood cells, aorta and lung were harvested for global gene expression analysis with subsequent Ingenuity Pathway Analysis and confirmatory qRT-PCR. Serum was collected for protein profiling...- Systemic immune cell response in rats after pulmonary exposure to manganese-containing particles collected from welding aerosolsJames M Antonini
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
J Immunotoxicol 9:184-92. 2012.... - Engineered nanoparticle respiratory exposure and potential risks for cardiovascular toxicity: predictive tests and biomarkersPetia P Simeonova
Tissue Injury Team, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
Inhal Toxicol 21:68-73. 2009..Future studies to evaluate the systemic effects of carbon nanotube exposure under workplace or environmental exposure paradigms should be conducted... - Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fumePatti C Zeidler-Erdely
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, USA
Part Fibre Toxicol 5:12. 2008..abstract:.. - Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol dietsAaron Erdely
Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America
PLoS ONE 5:e15253. 2010..These results raise the possibility that systemic changes in arginase activity and global arginine bioavailability may be contributing factors in the initiation and/or progression of cardiovascular disease... - Immunotoxicology of arc welding fume: Worker and experimental animal studiesPatti C Zeidler-Erdely
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
J Immunotoxicol 9:411-25. 2012..The objective of this report was to review both human and animal studies that have examined the effect of welding fume pulmonary exposure on local and systemic immune responses... - Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkersAaron Erdely
Toxicology and Molecular Biology Branch and Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
Nano Lett 9:36-43. 2009..The approach described here will foster the development of biomarkers for application in human screening of nanoparticle exposure... 
Renal neuronal nitric oxide synthase protein expression as a marker of renal injuryAttila J Szabo
Department of Physiology, West Virginia University, Morgantown, West Virginia 26506, USA
Kidney Int 64:1765-71. 2003..CONCLUSION: Renal nNOS abundance was reduced in the 5/6 A/I model of renal disease when plasma creatinine> approximately 1 mg/dL and when> approximately 20% of remaining glomeruli were sclerosed...