- Sensitive and specific peak detection for SELDI-TOF mass spectrometry using a wavelet/neural-network based approachVincent A Emanuele
Chronic and Viral Diseases Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e48103. 2012..The new method was applied to data collected from a study of cervical mucus for the early detection of cervical cancer in HPV infected women. The method shows promise in addressing the ongoing SELDI reproducibility issues...
- Benchmarking currently available SELDI-TOF MS preprocessing techniquesVincent A Emanuele
Chronic Viral Diseases Branch, Nation Center for Zoonotic, Vector born and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Proteomics 9:1754-62. 2009..There is considerable opportunity for future contributions improving the signal processing of SELDI spectra...
- Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry dataVincent A Emanuele
School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA
BMC Bioinformatics 11:512. 2010..Bottom-up approaches to preprocessing that emphasize modeling SELDI data acquisition are promising avenues of research to find the needed improvements in reproducibility...