Dennis Ellenberger

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique
    Ilesh V Jani
    Instituto Nacional de Saude, Maputo, Mozambique
    J Clin Microbiol 50:1458-60. 2012
  2. ncbi request reprint Generation of a consensus sequence from prevalent and incident HIV-1 infections in West Africa to guide AIDS vaccine development
    Dennis L Ellenberger
    HIV and Retrovirology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Virology 302:155-63. 2002
  3. ncbi request reprint HIV-1 DNA/MVA vaccination reduces the per exposure probability of infection during repeated mucosal SHIV challenges
    Dennis Ellenberger
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G 19, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virology 352:216-25. 2006
  4. ncbi request reprint Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs
    Dennis Ellenberger
    Laboratory Branch, Centers for Disease Control and Prevention, Mail Stop G 19, Atlanta, GA 30333, USA
    Virology 340:21-32. 2005
  5. ncbi request reprint Absence of SHIV infection in gut and lymph node tissues in rhesus monkeys after repeated rectal challenges following HIV-1 DNA/MVA immunizations
    Michael Aidoo
    Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop A 25, Atlanta, GA 30333, USA
    Vaccine 25:6474-81. 2007
  6. pmc Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques
    Katherine Butler
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    AIDS Res Hum Retroviruses 29:1091-4. 2013
  7. doi request reprint Generation of a dual RT Env SHIV that is infectious in rhesus macaques
    James M Smith
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Med Primatol 39:213-23. 2010
  8. doi request reprint Repeated rectal SHIVSF162P3 exposures do not consistently induce sustained T cell responses prior to systemic infection in the repeat-low dose preclinical macaque model
    Ellen N Kersh
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 25:905-17. 2009
  9. ncbi request reprint Optimization of a multi-gene HIV-1 recombinant subtype CRF02_AG DNA vaccine for expression of multiple immunogenic forms
    Dennis Ellenberger
    HIV and Retrovirology Branch, Division of AIDS, STD, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    Virology 319:118-30. 2004
  10. ncbi request reprint Measurement of HIV-1 CRF02_AG-specific T cell responses indicates the dominance of a p24gag epitope in blood donors in Abidjan, Cote d'Ivoire
    Ann Chahroudi
    Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 192:1417-21. 2005

Collaborators

Detail Information

Publications14

  1. pmc Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique
    Ilesh V Jani
    Instituto Nacional de Saude, Maputo, Mozambique
    J Clin Microbiol 50:1458-60. 2012
    ..The increased throughput of testing with minimal operator interference in performing the CAPTAQ assay clearly demonstrated that this method is an improvement over the Roche Amplicor HIV-1 DNA test, version 1.5...
  2. ncbi request reprint Generation of a consensus sequence from prevalent and incident HIV-1 infections in West Africa to guide AIDS vaccine development
    Dennis L Ellenberger
    HIV and Retrovirology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Virology 302:155-63. 2002
    ..These data suggest that the consensus sequence generated from incident and prevalent infections may provide an appropriate sequence for a DNA vaccine and is largely representative of the major circulating viral strain...
  3. ncbi request reprint HIV-1 DNA/MVA vaccination reduces the per exposure probability of infection during repeated mucosal SHIV challenges
    Dennis Ellenberger
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G 19, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virology 352:216-25. 2006
    ..Therefore, improved non-human primate models for vaccine efficacy can provide novel insight and perhaps renew expectations for positive outcomes of human HIV clinical trials...
  4. ncbi request reprint Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs
    Dennis Ellenberger
    Laboratory Branch, Centers for Disease Control and Prevention, Mail Stop G 19, Atlanta, GA 30333, USA
    Virology 340:21-32. 2005
    ..They also suggest that expression of different forms of VLP has a significant effect on elicited cellular and humoral immunity...
  5. ncbi request reprint Absence of SHIV infection in gut and lymph node tissues in rhesus monkeys after repeated rectal challenges following HIV-1 DNA/MVA immunizations
    Michael Aidoo
    Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop A 25, Atlanta, GA 30333, USA
    Vaccine 25:6474-81. 2007
    ..These findings demonstrate that some vaccinated macaques appeared to be free from the challenge virus. Therefore, such T cell-based vaccines may provide some protection when challenge virus doses approach physiological equivalencies...
  6. pmc Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques
    Katherine Butler
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    AIDS Res Hum Retroviruses 29:1091-4. 2013
    ..The finding that TRIM5 alleles do not restrict mucosal infection or ensuing replication rates suggests that SHIVSF162P3 is indeed suitable for RLD experimentation...
  7. doi request reprint Generation of a dual RT Env SHIV that is infectious in rhesus macaques
    James M Smith
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Med Primatol 39:213-23. 2010
    ..We describe construction of a dual SHIV containing both HIV RT and a CCR5-specific HIV envelope gene in a simian immunodeficiency virus backbone...
  8. doi request reprint Repeated rectal SHIVSF162P3 exposures do not consistently induce sustained T cell responses prior to systemic infection in the repeat-low dose preclinical macaque model
    Ellen N Kersh
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 25:905-17. 2009
    ..Our results provide further insights into the repeat exposure macaque model. We find that this model can be used for testing biomedical prevention strategies without concern of eliciting a systemic vaccination effect...
  9. ncbi request reprint Optimization of a multi-gene HIV-1 recombinant subtype CRF02_AG DNA vaccine for expression of multiple immunogenic forms
    Dennis Ellenberger
    HIV and Retrovirology Branch, Division of AIDS, STD, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    Virology 319:118-30. 2004
    ..The production of multiple antigenic forms, including fusion-competent VLPs, by candidate DNA vaccine constructs may provide immunologic advantages for induction of protective cellular and humoral responses against HIV-1 proteins...
  10. ncbi request reprint Measurement of HIV-1 CRF02_AG-specific T cell responses indicates the dominance of a p24gag epitope in blood donors in Abidjan, Cote d'Ivoire
    Ann Chahroudi
    Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 192:1417-21. 2005
    ..One frequently recognized peptide in p24(gag) was mapped to the optimal epitope (TPQDLNMML). Further studies of this epitope may be important for the development of HIV-1 vaccines for West Africa and West-Central Africa...
  11. pmc Impact of proficiency testing program for laboratories conducting early diagnosis of HIV-1 infection in infants in low- to middle-income countries
    Albert Garcia
    International Laboratory Branch, Division of Global HIV AIDS, Center for Global Health, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia, USA
    J Clin Microbiol 52:773-80. 2014
    ....
  12. ncbi request reprint Multiprotein HIV type 1 clade B DNA/MVA vaccine: construction, safety, and immunogenicity in Macaques
    James M Smith
    Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia 30329, USA
    AIDS Res Hum Retroviruses 20:654-65. 2004
    ....
  13. ncbi request reprint DNA/MVA vaccine for HIV type 1: effects of codon-optimization and the expression of aggregates or virus-like particles on the immunogenicity of the DNA prime
    James M Smith
    Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia 30329, USA
    AIDS Res Hum Retroviruses 20:1335-47. 2004
    ..Based on the breadth of the T cell response and a trend toward higher titers of anti-Env Ab, we are moving forward with human trials of the noncodon-optimized VLP-expressing DNA...
  14. ncbi request reprint Studies in macaques on cross-clade T cell responses elicited by a DNA/MVA AIDS vaccine, better conservation of CD8 than CD4 T cell responses
    James M Smith
    Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia 30329, USA
    AIDS Res Hum Retroviruses 21:140-4. 2005
    ..Thus, the ability of an HIV vaccine for one clade to protect against other clades may be more limited by the ability to provide CD4 T cell help than the ability to elicit CD8 effector functions...