Research Topics
Genomes and Genes | Min DingSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Occupational toxicology of nickel and nickel compoundsJinshun Zhao
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
J Environ Pathol Toxicol Oncol 28:177-208. 2009....
Luciferase reporter system for studying the effect of nanoparticles on gene expressionMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
Methods Mol Biol 906:403-14. 2012..Here we describe the Genetic Luciferase Reporter System as the method for detecting alteration of gene expression in response to external stimuli (e.g., nanoparticles)...- Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrinMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Int J Oncol 36:59-67. 2010..Moreover, to our knowledge, these findings provide the first molecular basis for the anti-carcinogenic action of quercitrin... - Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activityMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Biol Chem 281:17359-68. 2006..These finding demonstrate for the first time that a purified compound of anthocyanin inhibits tumor promoter-induced carcinogenesis and tumor metastasis in vivo... - Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathwayMin Ding
Pathology and Physiology Research Branch, NIOSH, 1095 Willowdale Rd, Morgantown, WV 26505, USA
Am J Physiol Lung Cell Mol Physiol 290:L291-7. 2006..These results demonstrate that PKCalpha and PKCepsilon are essential in silica-induced AP-1 activation through the MAP kinase (ERKs and p38 kinases) pathway... - Inhibition of AP-1 and neoplastic transformation by fresh apple peel extractMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Biol Chem 279:10670-6. 2004.... 
Cyanidin-3-glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2Mei Xu
Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY 40536, USA
Mol Cancer 9:285. 2010..Ethanol exposure causes the accumulation of intracellular reactive oxygen species (ROS). This study evaluated the effect of C3G on ethanol-induced breast cancer cell migration/invasion...- Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathwayJinshun Zhao
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26505, USA
J Nanobiotechnology 7:2. 2009..abstract:.. - Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acidRentian Feng
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Biol Chem 280:27888-95. 2005.... - Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathwayRentian Feng
Pathology and Physiology Research Branch, Helath Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Nutr Cancer 50:80-9. 2004.... - Differential role of hydrogen peroxide in UV-induced signal transductionMin Ding
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
Mol Cell Biochem 234:81-90. 2002..radical scavenger) did not inhibit any of these pathways. These results demonstrate that H2O2 generation is required for UV-induced phosphorylation of Akt and p70(S6k), and involved in activation of JNKs and p38 kinase, but not Erks... - Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen speciesLiying Wang
Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Cell Physiol 195:99-107. 2003..These results indicate that multiple oxidative species are involved in V (V)-induced lung inflammation and apoptosis, and that H(2)O(2) plays a major role in this process... - Titanium dioxide (TiO2) nanoparticles induce JB6 cell apoptosis through activation of the caspase-8/Bid and mitochondrial pathwaysJinshun Zhao
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
J Toxicol Environ Health A 72:1141-9. 2009..Unraveling the complex mechanisms associated with these events may provide further insights into TiO(2) nanoparticle-induced pathogenicity and potential to induce carcinogenicity... - Essential role of p53 in silica-induced apoptosisLiying Wang
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Am J Physiol Lung Cell Mol Physiol 288:L488-96. 2005..This finding may provide an important link in understanding the molecular mechanisms of silica-induced carcinogenesis and pathogenesis in the lung... - Antioxidant properties of fruit and vegetable juices: more to the story than ascorbic acidStephen S Leonard
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
Ann Clin Lab Sci 32:193-200. 2002..It appears that consumption of whole fruits and vegetables would be superior to an ascorbic acid supplement for antioxidant effectiveness... - The role of glycogen synthase kinase 3beta in the transformation of epidermal cellsCuiling Ma
Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Robert C Byrd Health Sciences Center, Morgantown, WV, USA
Cancer Res 67:7756-64. 2007..Together, these results indicate that GSK3beta plays an important role in skin tumorigenesis... - PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesisJing Fang
Mary Babb Randolph Cancer Center, Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 9300, USA
Cell Signal 19:2487-97. 2007.... - Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen speciesNing Gao
Mary Babb Randolph Cancer Center, Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, West Virginia 26506-9300, USA
J Biol Chem 277:31963-71. 2002..These results suggest that the expression of HIF-1 and VEGF induced by vanadate through PI3K/Akt may be an important signaling pathway in the vanadate-induced carcinogenesis, and ROS may play an important role... - Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathwayFei Chen
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
Proc Natl Acad Sci U S A 99:1990-5. 2002.... - Molecular mechanisms of Cr(VI)-induced carcinogenesisMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Mol Cell Biochem 234:293-300. 2002.... - Single cell gel electrophoresis assay (comet assay) for evaluating nanoparticles-induced DNA damage in cellsLinda Bowman
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
Methods Mol Biol 906:415-22. 2012..Here, we describe the method of alkaline comet assay to detect nanoparticle-induced DNA damage... - Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in miceLiying Wang
National Institute for Occupational Safety and Health, Pathology and Physiology Research Branch, Morgantown, WV 26505, USA
J Environ Pathol Toxicol Oncol 21:343-50. 2002..We conclude that apoptosis of neutrophils and clearance by alveolar macrophages are important mechanisms in the resolution of vanadium-induced lung inflammation... - Protective roles of NF-kappa B for chromium(VI)-induced cytotoxicity is revealed by expression of Ikappa B kinase-beta mutantFei Chen
Health Effects Laboratory Division, NIOSH, Morgantown, West Virginia 26505, USA
J Biol Chem 277:3342-9. 2002..Such inhibition may involve up-regulation of the expression of anti-death proteins including cIAP1 that prevents spontaneous caspase activation and subsequent cleavage of Bcl-xL protein... - Diseases caused by silica: mechanisms of injury and disease developmentMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Int Immunopharmacol 2:173-82. 2002..Silica-induced AP-1 activation, protooncogene expression, and the role of ROS in these processes are also briefly discussed...