F DeStefano

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Childhood vaccinations and risk of asthma
    Frank Destefano
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 21:498-504. 2002
  2. ncbi request reprint MMR vaccine and autism: an update of the scientific evidence
    Frank Destefano
    National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E61, Atlanta, Georgia 30333, USA
    Expert Rev Vaccines 3:19-22. 2004
  3. doi request reprint Factors associated with social contacts in four communities during the 2007-2008 influenza season
    F DeStefano
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Epidemiol Infect 139:1181-90. 2011
  4. ncbi request reprint Hepatitis B vaccine and risk of multiple sclerosis
    Frank Destefano
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Expert Rev Vaccines 1:461-6. 2002
  5. ncbi request reprint Vaccinations and risk of central nervous system demyelinating diseases in adults
    Frank Destefano
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Neurol 60:504-9. 2003
  6. ncbi request reprint Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitus
    F DeStefano
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Pediatrics 108:E112. 2001
  7. ncbi request reprint Autism and measles-mumps-rubella vaccination: controversy laid to rest?
    F DeStefano
    National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia 30341 3724, USA
    CNS Drugs 15:831-7. 2001
  8. ncbi request reprint Influenza vaccination in children with asthma in health maintenance organizations. Vaccine Safety Datalink Team
    P Kramarz
    Centers for Disease Control and Prevention, 1600 Clifton Road, MS E61, Atlanta, GA 30333, USA
    Vaccine 18:2288-94. 2000
  9. ncbi request reprint Does influenza vaccination exacerbate asthma? Analysis of a large cohort of children with asthma. Vaccine Safety Datalink Team
    P Kramarz
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Fam Med 9:617-23. 2000
  10. ncbi request reprint Challenges and controversies in immunization safety
    R T Chen
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Infect Dis Clin North Am 15:21-39, viii. 2001

Detail Information

Publications42

  1. ncbi request reprint Childhood vaccinations and risk of asthma
    Frank Destefano
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 21:498-504. 2002
    ..A few previous studies have suggested that childhood vaccines, particularly whole cell pertussis vaccine, may increase the risk of asthma. We evaluated the suggested association between childhood vaccinations and risk of asthma...
  2. ncbi request reprint MMR vaccine and autism: an update of the scientific evidence
    Frank Destefano
    National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E61, Atlanta, Georgia 30333, USA
    Expert Rev Vaccines 3:19-22. 2004
    ..The evidence now is convincing that the measles-mumps-rubella vaccine does not cause autism or any particular subtypes of autistic spectrum disorder...
  3. doi request reprint Factors associated with social contacts in four communities during the 2007-2008 influenza season
    F DeStefano
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Epidemiol Infect 139:1181-90. 2011
    ..These results should be useful for modelling influenza epidemics and pandemics and in planning mitigation and response strategies...
  4. ncbi request reprint Hepatitis B vaccine and risk of multiple sclerosis
    Frank Destefano
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Expert Rev Vaccines 1:461-6. 2002
    ..The US Institute of Medicine and other review panels have concluded that the evidence favors rejection of a causal association between hepatitis B vaccine and multiple sclerosis...
  5. ncbi request reprint Vaccinations and risk of central nervous system demyelinating diseases in adults
    Frank Destefano
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Neurol 60:504-9. 2003
    ..Several case reports of the onset or exacerbation of multiple sclerosis or other demyelinating conditions shortly after vaccination have suggested that vaccines may increase the risk of demyelinating diseases...
  6. ncbi request reprint Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitus
    F DeStefano
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Pediatrics 108:E112. 2001
    ..To evaluate suggested associations between childhood vaccinations, particularly against hepatitis B and Haemophilus influenzae type b, and risk of developing type 1 diabetes; and to determine whether timing of vaccination influences risk...
  7. ncbi request reprint Autism and measles-mumps-rubella vaccination: controversy laid to rest?
    F DeStefano
    National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia 30341 3724, USA
    CNS Drugs 15:831-7. 2001
    ..Currently, the weight of the available epidemiological and related evidence does not support a causal association between MMR vaccine, or any other vaccine or vaccine constituent, and autism...
  8. ncbi request reprint Influenza vaccination in children with asthma in health maintenance organizations. Vaccine Safety Datalink Team
    P Kramarz
    Centers for Disease Control and Prevention, 1600 Clifton Road, MS E61, Atlanta, GA 30333, USA
    Vaccine 18:2288-94. 2000
    ..Vaccination coverage could be increased by taking advantage of all opportunities to vaccinate children with asthma whenever they make clinic visits in the fall and early winter...
  9. ncbi request reprint Does influenza vaccination exacerbate asthma? Analysis of a large cohort of children with asthma. Vaccine Safety Datalink Team
    P Kramarz
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Fam Med 9:617-23. 2000
    ..One reason for low influenza vaccine coverage among children with asthma may be concern that influenza vaccination may induce an exacerbation of asthma...
  10. ncbi request reprint Challenges and controversies in immunization safety
    R T Chen
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Infect Dis Clin North Am 15:21-39, viii. 2001
    ..It also provides information on how various safety research is conducted, some of the concurrent challenges, and finally, some guidance on communicating with patients on vaccine risks...
  11. pmc The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA
    R T Chen
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Bull World Health Organ 78:186-94. 2000
    ....
  12. ncbi request reprint The incidence of Kawasaki syndrome in West Coast health maintenance organizations
    E D Belay
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 19:828-32. 2000
    ..Kawasaki syndrome (KS) causes an acute vasculitis of unknown etiology. It is a leading cause of acquired heart disease of children in Japan and the United States...
  13. ncbi request reprint The Vaccine Safety Datalink project
    F DeStefano
    National Immunization Program MS F34, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Pharmacoepidemiol Drug Saf 10:403-6. 2001
    ..A cohort study was conducted that allowed estimation of incidence rates of intussusception and attributable risks associated with rotavirus vaccine...
  14. ncbi request reprint Does influenza vaccination prevent asthma exacerbations in children?
    P Kramarz
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Pediatr 138:306-10. 2001
    ..The effectiveness of influenza vaccine in preventing influenza-related asthma exacerbations, however, is not known. We evaluated influenza vaccine effectiveness in protecting children against influenza-related asthma exacerbations...
  15. ncbi request reprint Population-based study of rotavirus vaccination and intussusception
    P Kramarz
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 20:410-6. 2001
    ..0. The attributable risk was one case of intussusception per 11 073 children vaccinated. CONCLUSIONS: RRV-TV is associated with an increased risk of intussusception. The risk is greatest 3 to 7 days after the first vaccination dose...
  16. ncbi request reprint Immunity to tetanus is protective against the development of multiple sclerosis
    T Verstraeten
    Epidemic Intelligence Service EIS Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Altanta, GA, USA
    Med Hypotheses 65:966-9. 2005
    ..Laboratory evidence could be sought by testing the effect of tetanus toxoid on experimental allergic encephalomyelitis, the experimental animal model of MS...
  17. ncbi request reprint MMR vaccine and autism: a review of the evidence for a causal association
    F DeStefano
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F34, Atlanta, GA 30341 3724, USA
    Mol Psychiatry 7:S51-2. 2002
  18. ncbi request reprint Vaccines and autism: evidence does not support a causal association
    F DeStefano
    Statistics and Epidemiology Unit, RTI International, Atlanta, Georgia, USA
    Clin Pharmacol Ther 82:756-9. 2007
    ....
  19. ncbi request reprint Epidemiology of autoimmune reactions induced by vaccination
    R T Chen
    Vaccine Safety and Development Activity, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Autoimmun 16:309-18. 2001
    ..Examples include the possible association of immunization and multiple sclerosis (and other demyelinating diseases), type 1 diabetes mellitus, Guillain-Barre Syndrome, idiopathic thrombocytopenic purpura, and rheumatoid arthritis...
  20. ncbi request reprint Hepatitis B vaccine and risk of multiple sclerosis
    Frank Destefano
    Pharmacoepidemiol Drug Saf 16:705-7, author reply 707-8. 2007
  21. ncbi request reprint Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years
    William W Thompson
    National Center for Immunizations and Respiratory Diseases, Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 357:1281-92. 2007
    ..It has been hypothesized that early exposure to thimerosal, a mercury-containing preservative used in vaccines and immune globulin preparations, is associated with neuropsychological deficits in children...
  22. ncbi request reprint Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study
    Frank Destefano
    Neurology 64:1317; author reply 1317. 2005
  23. ncbi request reprint Guillain-Barré syndrome following influenza vaccination
    Penina Haber
    Immunization Safety Branch, Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 292:2478-81. 2004
    ..Guillain-Barre syndrome remains the most frequent neurological condition reported after influenza vaccination to the Vaccine Adverse Events Reporting System (VAERS) since its inception in 1990...
  24. ncbi request reprint Letter to the editor. The safety of thimerosal in newborn and infant vaccines
    William W Thompson
    Vaccine 23:281-2. 2004
  25. ncbi request reprint Understanding vaccine safety information from the Vaccine Adverse Event Reporting System
    Frederick Varricchio
    Division of Epidemiology, Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration NIH DHHS, Rockville MD, USA
    Pediatr Infect Dis J 23:287-94. 2004
    ..Confirmation in a controlled study is usually required. An understanding of the system's defined objectives and inherent drawbacks is vital to the effective use of VAERS data in vaccine safety investigations...
  26. ncbi request reprint Age at first measles-mumps-rubella vaccination in children with autism and school-matched control subjects: a population-based study in metropolitan atlanta
    Frank Destefano
    National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 113:259-66. 2004
    ..To compare ages at first measles-mumps-rubella (MMR) vaccination between children with autism and children who did not have autism in the total population and in selected subgroups, including children with regression in development...
  27. ncbi request reprint Hepatitis B vaccination among adolescents in 3 large health maintenance organizations
    Idalia M Gonzalez
    Epidemiology Program Office, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 110:929-34. 2002
    ..Little is known about the implementation of these recommendations in a managed care setting. The objective of this study was to determine the impact of ACIP recommendations on HB vaccination among adolescents in 3 managed care settings...
  28. ncbi request reprint Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases
    Thomas Verstraeten
    Epidemic Intelligence Service Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 112:1039-48. 2003
    ..To assess the possible toxicity of thimerosal-containing vaccines (TCVs) among infants...
  29. ncbi request reprint Vaccine safety surveillance using large linked databases: opportunities, hazards and proposed guidelines
    Thomas Verstraeten
    GlaxoSmithKline Biologicals, Rixensart, Belgium
    Expert Rev Vaccines 2:21-9. 2003
    ..We also offer our opinion on the future use of large linked databases for vaccine safety surveillance purposes...
  30. ncbi request reprint Wheezing lower respiratory disease and vaccination of full-term infants
    John P Mullooly
    Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227, USA
    Pharmacoepidemiol Drug Saf 11:21-30. 2002
    ..There have been speculations that increases in vaccinations have caused recent increases in wheezing lower respiratory disease during infancy. We assess possible associations between vaccines and incidence of wheezing in full-term infants...
  31. ncbi request reprint Risk of anaphylaxis after vaccination of children and adolescents
    Kari Bohlke
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101 1448, USA
    Pediatrics 112:815-20. 2003
    ..To quantify the risk of anaphylaxis after vaccination of children and adolescents...
  32. ncbi request reprint Safety of trivalent inactivated influenza vaccine in children 6 to 23 months old
    Simon J Hambidge
    Clinical Research Unit, Kaiser Permanente Colorado, Denver, CO 80237 8066, USA
    JAMA 296:1990-7. 2006
    ..Beginning with the winter season of 2004-2005, influenza vaccination has been recommended for all children 6 to 23 months old in the United States. However, its safety in young children has not been adequately studied in large populations...
  33. ncbi request reprint Influenza vaccination and Guillain Barré syndrome
    Penina Haber
    Clin Immunol 109:359; author reply 360-1. 2003
  34. ncbi request reprint A potential signal of Bell's palsy after parenteral inactivated influenza vaccines: reports to the Vaccine Adverse Event Reporting System (VAERS)--United States, 1991-2001
    Weigong Zhou
    Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pharmacoepidemiol Drug Saf 13:505-10. 2004
    ..We reviewed reports in the Vaccine Adverse Event Reporting System (VAERS) to assess if parenteral inactivated influenza vaccines (influenza vaccines) may also increase the risk for Bell's palsy...
  35. ncbi request reprint Infant vaccinations and childhood asthma among full-term infants
    Julie E Maher
    Center for Health Research, Kaiser Permanente Northwest, 3800 N Interstate, Portland, OR 97227 1110, USA
    Pharmacoepidemiol Drug Saf 13:1-9. 2004
    ..To determine if infant vaccinations are associated with childhood asthma among full-term infants. The secondary objective was to describe relationships between characteristics of infant wheezing and childhood asthma...
  36. ncbi request reprint Epidemiology of anaphylaxis among children and adolescents enrolled in a health maintenance organization
    Kari Bohlke
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101 1448, USA
    J Allergy Clin Immunol 113:536-42. 2004
    ..There is little information about the incidence of anaphylaxis from all causes...
  37. ncbi request reprint Compliance with the recommendations for 2 doses of trivalent inactivated influenza vaccine in children less than 9 years of age receiving influenza vaccine for the first time: a Vaccine Safety Datalink study
    Lisa A Jackson
    Group Health Center for Health Studies, Seattle, Washington, USA
    Pediatrics 118:2032-7. 2006
    ..We conducted a population-based retrospective cohort study to evaluate compliance with the 2-dose trivalent inactivated influenza vaccine recommendations...
  38. ncbi request reprint A retrospective cohort study of the association of varicella vaccine failure with asthma, steroid use, age at vaccination, and measles-mumps-rubella vaccination
    Thomas Verstraeten
    Epidemic Intelligence Service Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 112:e98-103. 2003
    ..We assessed the association of varicella breakthrough with asthma, steroids, age at varicella vaccination, and timing of measles-mumps-rubella (MMR) vaccination...
  39. ncbi request reprint Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old children
    Kathleen M Neuzil
    Program for Appropriate Technology in Health, School of Medicine, University of Washington, Seattle, Seattle, WA 98107, USA
    J Infect Dis 194:1032-9. 2006
    ..This study assessed the need for a second dose of TIV in this age group...
  40. ncbi request reprint Lack of association between hepatitis B birth immunization and neonatal death: a population-based study from the vaccine safety datalink project
    Eileen M Eriksen
    UCLA Center for Vaccine Research, Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Pediatr Infect Dis J 23:656-62. 2004
    ..There have been no population-based studies of the potential association between neonatal death and newborn immunization with hepatitis B vaccine (HBV)...
  41. ncbi request reprint Trends in diagnosis rates for autism and ADHD at hospital discharge in the context of other psychiatric diagnoses
    David S Mandell
    Center for Mental Health Policy and Services Research, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, USA
    Psychiatr Serv 56:56-62. 2005
    ....
  42. ncbi request reprint MMR vaccination and autism: is there a link?
    Frank Destefano
    Expert Opin Drug Saf 1:115-20. 2002
    ..Currently, the weight of the available epidemiological and related evidence does not support a causal link between MMR vaccine and autism...