Research Topics
| B K DeSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
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Detail Information
Publications
Purification and characterization of Streptococcus pneumoniae palmitoylated pneumococcal surface adhesin A expressed in Escherichia coliB K De
Division of Bacterial and Mycotic Diseases, and Biotechnology Core Facility Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Vaccine 18:1811-21. 2000..coli-expressed rPsaA is palmitoylated and closely resembles the native protein in structure and immunogenicity. It was also observed to elicit measurable protection against nasopharyngeal carriage with S. pneumoniae...- Baculovirus expression, purification and evaluation of recombinant pneumococcal surface adhesin A of Streptococcus pneumoniaeB K De
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pathobiology 67:115-22. 1999..90% survival rates) when challenged with S. pneumoniae serotype 6B. These results indicate that rPsaA is immunogenic and elicits protective antibody in mice similar to native protein... 
A two-component direct fluorescent-antibody assay for rapid identification of Bacillus anthracisBarun K De
Centers for Desease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 8:1060-5. 2002..The two-component DFA assay is a sensitive, specific, and rapid confirmatory test for B. anthracis in cultures and may be useful directly on clinical specimens...- Identification of an unusual Brucella strain (BO2) from a lung biopsy in a 52 year-old patient with chronic destructive pneumoniaRebekah V Tiller
Division of Foodborne, Bacterial, and Mycotic Diseases and Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
BMC Microbiol 10:23. 2010..In this study we report on the identification of an unusual Brucella-like strain (BO2) isolated from a lung biopsy in a 52-year-old patient in Australia with a clinical history of chronic destructive pneumonia... - Novel Brucella strain (BO1) associated with a prosthetic breast implant infectionBarun K De
Centers for Disease Control and Prevention, Mail Stop G34, 1600 Clifton Rd, Atlanta, GA 30333, USA
J Clin Microbiol 46:43-9. 2008..confirms that the isolate is much more closely related to Brucella than to Ochrobactrum spp., and thus the isolate likely represents an atypical and novel strain within the genus Brucella... - Characterization of novel Brucella strains originating from wild native rodent species in North Queensland, AustraliaRebekah V Tiller
Centers for Disease Control and Prevention, Mail Stop G34, 1600 Clifton Road, Atlanta, GA 30333, USA
Appl Environ Microbiol 76:5837-45. 2010..Our findings strongly suggest that this group of Brucella strains isolated from wild Australian rodents defines a new species in the Brucella genus... - Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthraxAlex R Hoffmaster
Epidemiologic Investigations Laboratory, Meningitis and Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G34, Atlanta, GA 30333, USA
Proc Natl Acad Sci U S A 101:8449-54. 2004..In this study, we combined a public health approach with genome analysis to provide insight into the correlation of phenotypic characteristics and their genetic basis... - Effect of carbon dioxide on broth microdilution susceptibility testing of Brucella sppDavid R Lonsway
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 48:952-6. 2010..Six antimicrobial agents were tested against 39 Brucella isolates. Aminoglycoside MICs tended to be 1 log2 dilution higher in CO2 than in AA; tetracycline-class MICs to be 1 log2 dilution lower in CO2... - Comparison of two multiple-locus variable-number tandem-repeat analysis methods for molecular strain typing of human Brucella melitensis isolates from the Middle EastRebekah V Tiller
US Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 47:2226-31. 2009..melitensis strains... - Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genesAlex R Hoffmaster
Epidemiologic Investigations Laboratory, Meningitis and Special Pathogens Branch, MS G34, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia 30333, USA
J Clin Microbiol 44:3352-60. 2006..cereus strains can cause severe and even fatal infections in patients who appear to be otherwise healthy... - Use of 16S rRNA gene sequencing for rapid confirmatory identification of Brucella isolatesJay E Gee
Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, MS D11, 1600 Clifton Rd, N E, Atlanta, GA 30333, USA
J Clin Microbiol 42:3649-54. 2004..and their differentiation from closely related organisms... - Standardization and denoising algorithms for mass spectra to classify whole-organism bacterial specimensGlen A Satten
Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Bioinformatics 20:3128-36. 2004..The method resulted in zero prediction errors in the training samples and in two test datasets having 240 and 300 spectra, respectively... - Use of 16S rRNA gene sequencing for rapid identification and differentiation of Burkholderia pseudomallei and B. malleiJay E Gee
Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:4647-54. 2003..This report provides a basis for rapidly identifying and differentiating B. pseudomallei and B. mallei by molecular methods... - Analysis of recombinant acylated pneumococcal surface adhesin A of Streptococcus pneumoniae by mass spectrometryBarun K De
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Arch Biochem Biophys 419:147-57. 2003..The availability of well-characterized rPsaA will facilitate the continued research and development of protein-based vaccines for the prevention of pneumococcal disease... - Isolation of human T-cell lymphotropic virus type 2 from Guaymi Indians in PanamaM D Lairmore
Retrovirus Disease Branch, Centers for Disease Control, Atlanta, GA 30333
Proc Natl Acad Sci U S A 87:8840-4. 1990.... - Real-time PCR assays of single-nucleotide polymorphisms defining the major Brucella cladesJeffrey T Foster
Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ 86011 5640, USA
J Clin Microbiol 46:296-301. 2008..These PCR assays provide a rapid and highly sensitive method of differentiating the major Brucella groups that will be valuable for clinical and forensic applications...