Research Topics
Species | Wayne D CrillSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopesWayne D Crill
Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, P O Box 2087, Fort Collins, CO 80522, USA
J Virol 78:13975-86. 2004..The third epitope consists of discontinuous residues that are structurally related to the strictly conserved tryptophan at dengue virus serotype 2 E-glycoprotein position 231...
A detailed mutagenesis study of flavivirus cross-reactive epitopes using West Nile virus-like particlesWayne D Crill
Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Service, PO Box 2087, Fort Collins, CO 80522, USA
J Gen Virol 88:1169-74. 2007..These results support and extend the conclusion that the fusion peptide region constitutes an immunodominant epitope stimulating antibodies with diverse patterns of cross-reactivity...
Humoral immune responses of dengue fever patients using epitope-specific serotype-2 virus-like particle antigensWayne D Crill
Arbovirus Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Service, Fort Collins, CO, USA
PLoS ONE 4:e4991. 2009....
Differentiation of West Nile and St. Louis encephalitis virus infections by use of noninfectious virus-like particles with reduced cross-reactivityJill A Roberson
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, CDC Foothills Campus, Fort Collins, CO 80521, USA
J Clin Microbiol 45:3167-74. 2007....
Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancementHolly R Hughes
Arboviral Diseases Branch, Division of Vector Borne Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Fort Collins, CO 80521, USA
Virol J 9:115. 2012....
Mutation analysis of the fusion domain region of St. Louis encephalitis virus envelope proteinNicole B Trainor
Arboviral Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Service, Post Office Box 2087, Fort Collins, CO 80522, USA
Virology 360:398-406. 2007..These results provide critical insight into the antigenic structure of the flaviviral E protein and toward development of species-specific diagnostic antigens that should improve both flavivirus diagnosis and estimates of disease burden...
A West Nile virus CD4 T cell epitope improves the immunogenicity of dengue virus serotype 2 vaccinesHolly R Hughes
Arboviral Diseases Branch, Division of Vector Borne Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Fort Collins, CO 80521, USA
Virology 424:129-37. 2012..Incorporating such potent epitopes into multivalent flavivirus vaccines could improve their immunogenicity and may help alleviate concerns of imbalanced immunity in multivalent vaccine approaches...
Sculpting humoral immunity through dengue vaccination to enhance protective immunityWayne D Crill
Arboviral Diseases Branch, Division of Vector Borne Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Service Fort Collins, CO, USA
Front Immunol 3:334. 2012..The sculpting of immune memory by the modified vaccine and resulting redirection of humoral immunity provide insight into DENV vaccine-induced immune responses...
Enzyme-linked immunosorbent assays using novel Japanese encephalitis virus antigen improve the accuracy of clinical diagnosis of flavivirus infectionsShyan Song Chiou
Graduate Institute of Veterinary Public Health, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan, Republic of China
Clin Vaccine Immunol 15:825-35. 2008..74 [WT] and 22 [KD]). The application and continued development of cross-reactivity-reduced antigens should improve both flavivirus infection serodiagnosis and estimates of disease burden...
