Fei Chen

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. request reprint
    Chen F, Castranova V. Beyond apoptosis of JNK1 in liver cancer. Cell Cycle. 2009;8:1145-7 pubmed
    ..Accordingly, we believe that targeting JNK1 is not only mechanistically sound but also clinically feasible for the treatment of HCC. ..
  2. Chen F, Zhang Z, Bower J, Lu Y, Leonard S, Ding M, et al. Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A. 2002;99:1990-5 pubmed
    ....
  3. request reprint
    Chen F, Lu Y, Castranova V, Li Z, Karin M. Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells. J Biol Chem. 2006;281:37142-9 pubmed
    ..These data thus suggest that IKKbeta provides inhibitory signals for cell mobility and growth. Deficiency in the Ikkbeta gene promotes cell mobilization, at least partially, through a ROS-dependent mechanism. ..

Detail Information

Publications3

  1. request reprint
    Chen F, Castranova V. Beyond apoptosis of JNK1 in liver cancer. Cell Cycle. 2009;8:1145-7 pubmed
    ..Accordingly, we believe that targeting JNK1 is not only mechanistically sound but also clinically feasible for the treatment of HCC. ..
  2. Chen F, Zhang Z, Bower J, Lu Y, Leonard S, Ding M, et al. Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A. 2002;99:1990-5 pubmed
    ....
  3. request reprint
    Chen F, Lu Y, Castranova V, Li Z, Karin M. Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells. J Biol Chem. 2006;281:37142-9 pubmed
    ..These data thus suggest that IKKbeta provides inhibitory signals for cell mobility and growth. Deficiency in the Ikkbeta gene promotes cell mobilization, at least partially, through a ROS-dependent mechanism. ..