Research Topics
| L E ChapmanSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Xenotransplantation, xenogeneic infections, biotechnology, and public healthLouisa E Chapman
Office of Critical Information Integration and Exchange, Centers for Disease Control and Prevention, Atlanta, GA, USA
Mt Sinai J Med 76:435-41. 2009..Mt Sinai J Med 76:435-441, 2009. (c) 2009 Mount Sinai School of Medicine...- A process for sentinel case review to assess causal relationships between smallpox vaccination and adverse outcomes, 2003-2004Louisa E Chapman
Epidemiology and Surveillance Division, National Immunization Program, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 46:S271-93. 2008..This review of sentinel cases augmented the ongoing safety review process and was transparent, but it shares limitations with other case-based causality-assessment methods... - Introduction: vaccination against smallpox in the posteradication eraLouisa E Chapman
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 46:S153-6. 2008..Although the execution of this national program posed multiple complex and varied challenges, the focus of this supplement is on vaccine-associated adverse events and vaccine safety... 
Xenotransplantation: public health risks--patient vs. society in an emerging fieldL E Chapman
CDC, 1600 Clifton Road, Mailstop A 12, Atlanta, GA 30333, USA
Curr Top Microbiol Immunol 278:23-45. 2003....- Implications of the advent of homozygous alpha l, 3-galactosyltransferase gene-deficient pigs on transmission of infectious agentsLouisa E Chapman
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Xenotransplantation 10:287-8. 2003 - Discriminators between hantavirus-infected and -uninfected persons enrolled in a trial of intravenous ribavirin for presumptive hantavirus pulmonary syndromeL E Chapman
Hantavirus Task Force, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 34:293-304. 2002..Patterns of clinical symptoms, the pace of clinical evolution, and specific clinical laboratory parameters discriminated between these 2 groups... - Intravenous ribavirin for hantavirus pulmonary syndrome: safety and tolerance during 1 year of open-label experience. Ribavirin Study GroupL E Chapman
Division of Viral and Rickettsial Diseases DVRD, National Center for Infectious Diseases NCID, Atlanta, GA, USA
Antivir Ther 4:211-9. 1999..A randomized, placebo-controlled trial that enrolls patients during the prodrome phase would be necessary to assess the efficacy and further define the safety of intravenous ribavirin for HPS... - Xenogeneic infections and public healthL E Chapman
Retrovirus Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Exp Pharmacol Physiol 26:1005-8. 1999..7. Laboratory based studies of xenograft survivors increase our ability to quantify xenotransplant-associated risks and, thereby, expand our capacity to make science-based assessments of appropriate public policy... - Identification of a human population infected with simian foamy virusesW Heneine
HIV and Retrovirology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Nat Med 4:403-7. 1998..The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections... - No evidence of infection with porcine endogenous retrovirus in recipients of porcine islet-cell xenograftsW Heneine
HIV and Retrovirology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Lancet 352:695-9. 1998..PERV is carried in the pig germline, and all recipients of porcine tissues or organs will be exposed to the virus... 
Infectious disease issues in xenotransplantationR S Boneva
HIV AIDS and Retrovirology Branch, Division of AIDS, STD and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Microbiol Rev 14:1-14. 2001..Thus, further trials should continue under regulatory oversight, with close clinical and laboratory monitoring for potential xenogeneic infections...- Simian foamy virus infection in a blood donorR S Boneva
Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Transfusion 42:886-91. 2002..Human-to-human transmission of SFV through transfusion and its pathogenicity have not been studied... - Polymerase chain reaction assays for the diagnosis of infection with the porcine endogenous retrovirus and the detection of pig cells in human and nonhuman recipients of pig xenograftsW M Switzer
Division of AIDS, Sexually Transmitted Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
Transplantation 68:183-8. 1999..The ability of PERV to infect human cells in vitro has heightened safety concerns regarding the transmission of PERV to pig xenograft recipients... - Lack of cross-species transmission of porcine endogenous retrovirus infection to nonhuman primate recipients of porcine cells, tissues, or organsW M Switzer
Division of AIDS, STDs, and TB Research Laboratory, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Transplantation 71:959-65. 2001..These findings suggest that PERV is not easily transmitted to these NHP species through these types of xenografts... - Investigation of retroviral involvement in chronic fatigue syndromeT M Folks
Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta, GA 30333
Ciba Found Symp 173:160-6; discussion 166-75. 1993..Our findings suggest that these agents, at least as markers, are non-distinguishing for CFS and that other factors may be confounding the resolution of an aetiology to this syndrome... - Mucosal and systemic antibody responses in humans infected with simian foamy virusJames E Cummins
HIV and Retrovirology Branch, Division of AIDS, STD, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 79:13186-9. 2005..These results provide a first comparative evaluation of SFV-specific host mucosal humoral immunity in infected humans and chimpanzees that is characterized by a predominant IgG response and a virtually absent IgA response... - Recommendations for postexposure interventions to prevent infection with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus, and tetanus in persons wounded during bombings and other mass-casualty events--United States, 2008: recommendatLouisa E Chapman
National Center for Immunizations and Respiratory Diseases, CDC, Mailstop D 68, 1600 Clifton Road, N E, Atlanta, GA 30333, USA
MMWR Recomm Rep 57:1-21; quiz CE1-4. 2008..S. federal public health officials and reflect the experience and input of public health officials at all levels of government and the acute injury response community... - Myocarditis, pericarditis, and dilated cardiomyopathy after smallpox vaccination among civilians in the United States, January-October 2003Juliette Morgan
Centers for Disease Control and Prevention and 2Department of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA
Clin Infect Dis 46:S242-50. 2008..We describe an association between smallpox vaccination, using the US vaccinia strain, and myo/pericarditis among civilians... - Ischemic cardiac events during the Department of Health and Human Services Smallpox Vaccination Program, 2003David L Swerdlow
Smallpox Vaccine Adverse Events Monitoring and Response Activity, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 46:S234-41. 2008..10; 95% PI, 3.5-15.7). After persons with >/=3 cardiac risk factors or known heart disease were deferred from vaccination, no ICEs were reported among an additional 6638 vaccinees... - Adverse events associated with smallpox vaccination in the United States, January-October 2003Christine G Casey
Smallpox Vaccine Adverse Event Monitoring and Response Activity, Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 294:2734-43. 2005.... - Surveillance guidelines for smallpox vaccine (vaccinia) adverse reactionsChristine Casey
Immunization Safety Office, Office of the Chief Science Officer, Office of the Director, Atlanta, GA 30329, USA
MMWR Recomm Rep 55:1-16. 2006..The smallpox vaccine surveillance case definitions presented in the report can be used in future vaccination programs to ensure uniform reporting guidelines and case classification... - Neurologic adverse events associated with smallpox vaccination in the United States, 2002-2004James J Sejvar
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 294:2744-50. 2005..The reinstatement of smallpox vaccination in the United States in response to possible bioterrorism renewed concerns about vaccine-related adverse neurologic events... - Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primatesWilliam M Switzer
HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 78:2780-9. 2004..Our data highlight the importance of studies to better define the public health implications of zoonotic SFV infections... - Clinical and virological characterization of persistent human infection with simian foamy virusesRoumiana S Boneva
HIV and Retrovirology Branch, Division of AIDS, STD and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
AIDS Res Hum Retroviruses 23:1330-7. 2007..SFV likely transmits to humans through both percutaneous and mucocutaneous exposures to NHP body fluids. Limited follow-up has not identified SFV-associated illness and secondary transmission among humans... - Genetic characterization of wild-type genotype VII hepatitis A virusKaren Z Ching
Hepatitis Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE A33, Atlanta, GA 30333, USA
J Gen Virol 83:53-60. 2002..While nucleotide variability within the three functional coding regions did not differ, the P3D region was found to have the largest number of amino acid changes compared to HM-175... - Recommendations for prevention of and therapy for exposure to B virus (cercopithecine herpesvirus 1)Jeffrey I Cohen
Medical Virology Section, Laboratory of Clinical Investigation, National Institutes of Health, Bethesda, Maryland 20892, USA
Clin Infect Dis 35:1191-203. 2002..The present report updates previous recommendations for the prevention, evaluation, and treatment of B virus infection in humans and considers the role of newer antiviral agents in postexposure prophylaxis...