Carolyn M Black

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Multicenter study of nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in children being evaluated for sexual abuse
    Carolyn M Black
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatr Infect Dis J 28:608-13. 2009
  2. pmc Head-to-head multicenter comparison of DNA probe and nucleic acid amplification tests for Chlamydia trachomatis infection in women performed with an improved reference standard
    Carolyn M Black
    National Center for Infectious Diseases, Mailstop C17, Centers for Disease Control and Prevention CDC, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    J Clin Microbiol 40:3757-63. 2002
  3. pmc Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines
    Qing He
    National Center for Infectious Disease, CDC, Atlanta, GA, USA
    Immunology 122:28-37. 2007
  4. ncbi request reprint Immunogenicity and protection against genital Chlamydia infection and its complications by a multisubunit candidate vaccine
    Godwin O Ifere
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Microbiol Immunol Infect 40:188-200. 2007
  5. pmc Involvement of LEK1 in dendritic cell regulation of T cell immunity against Chlamydia
    Qing He
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Immunol 181:4037-42. 2008
  6. pmc Role of T lymphocytes in the pathogenesis of Chlamydia disease
    Joseph U Igietseme
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    J Infect Dis 200:926-34. 2009
  7. ncbi request reprint Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents
    Erika Samoff
    Division of Sexually Transmitted Disease Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Epidemiol 162:668-75. 2005
  8. ncbi request reprint The effect of correct and consistent condom use on chlamydial and gonococcal infection among urban adolescents
    Gabriela Paz-Bailey
    National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Arch Pediatr Adolesc Med 159:536-42. 2005
  9. ncbi request reprint Molecular basis for the potency of IL-10-deficient dendritic cells as a highly efficient APC system for activating Th1 response
    Qing He
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Immunol 174:4860-9. 2005
  10. pmc Development of PCR assays for detection of Trichomonas vaginalis in urine specimens
    Claudiu I Bandea
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 51:1298-300. 2013

Collaborators

Detail Information

Publications38

  1. doi request reprint Multicenter study of nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in children being evaluated for sexual abuse
    Carolyn M Black
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatr Infect Dis J 28:608-13. 2009
    ..In adults, nucleic acid amplification tests (NAATs) are superior to culture for CT, but these tests have been insufficiently evaluated in pediatric populations for forensic purposes...
  2. pmc Head-to-head multicenter comparison of DNA probe and nucleic acid amplification tests for Chlamydia trachomatis infection in women performed with an improved reference standard
    Carolyn M Black
    National Center for Infectious Diseases, Mailstop C17, Centers for Disease Control and Prevention CDC, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    J Clin Microbiol 40:3757-63. 2002
    ..trachomatis infections in women. In our study, NAATs improved the detection of infected women by 17 to 38% compared to PACE 2...
  3. pmc Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines
    Qing He
    National Center for Infectious Disease, CDC, Atlanta, GA, USA
    Immunology 122:28-37. 2007
    ..Because live attenuated influenza virus vaccines are safe and acceptable for human use, they may provide a new and reliable approach to deliver efficacious vaccines against sexually transmitted diseases...
  4. ncbi request reprint Immunogenicity and protection against genital Chlamydia infection and its complications by a multisubunit candidate vaccine
    Godwin O Ifere
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Microbiol Immunol Infect 40:188-200. 2007
    ..We examined whether a vaccine composed of a combination of the major outer membrane protein (MOMP) and porin B protein (PorB) of C. trachomatis would have a protective advantage over a single subunit construct...
  5. pmc Involvement of LEK1 in dendritic cell regulation of T cell immunity against Chlamydia
    Qing He
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Immunol 181:4037-42. 2008
    ..Targeted modulation of LEK1 expression provides a novel strategy for augmenting the immunostimulatory function of DCs for inducing an effective immunity against pathogens...
  6. pmc Role of T lymphocytes in the pathogenesis of Chlamydia disease
    Joseph U Igietseme
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    J Infect Dis 200:926-34. 2009
    ..Furthermore, T cell subsets, especially CD8 T cells, play a major role in Chlamydia-induced infertility. The results have important implications for the immunopathogenesis of chlamydial disease and new vaccine strategies...
  7. ncbi request reprint Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents
    Erika Samoff
    Division of Sexually Transmitted Disease Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Epidemiol 162:668-75. 2005
    ..8, 95% confidence interval: 1.6, 4.9). The association between chlamydia infection and cervical cancer may be due to an effect of chlamydia infection on persistence of high-risk HPV...
  8. ncbi request reprint The effect of correct and consistent condom use on chlamydial and gonococcal infection among urban adolescents
    Gabriela Paz-Bailey
    National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Arch Pediatr Adolesc Med 159:536-42. 2005
    ..To evaluate the relationship between self-reported correct and consistent condom use and chlamydial and gonococcal infection...
  9. ncbi request reprint Molecular basis for the potency of IL-10-deficient dendritic cells as a highly efficient APC system for activating Th1 response
    Qing He
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Immunol 174:4860-9. 2005
    ..Collectively, these results provide a molecular basis for the high Th1-activating capacity of IL-10KO APC and may provide unique immunomodulation targets when designing vaccines against pathogens controlled by T cell immunity...
  10. pmc Development of PCR assays for detection of Trichomonas vaginalis in urine specimens
    Claudiu I Bandea
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 51:1298-300. 2013
    ..vaginalis in urine, a noninvasive specimen, and development of a protocol for differentiating among Trichomonas species that commonly infect humans...
  11. pmc Evaluation of the rapid BioStar optical immunoassay for detection of Chlamydia trachomatis in adolescent women
    Claudiu I Bandea
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, MS C 17, 1600 Clifton Rd, Atlanta, GA 30333, USA
    J Clin Microbiol 47:215-6. 2009
    ..4%, respectively. Due to its relatively low sensitivity, the BioStar Chlamydia OIA should only be used in conjunction with more sensitive laboratory tests unless laboratory tests are unavailable or timely return for treatment is unlikely...
  12. ncbi request reprint Host inflammatory response and development of complications of Chlamydia trachomatis genital infection in CCR5-deficient mice and subfertile women with the CCR5delta32 gene deletion
    Erika L Barr
    Clark Atlanta University, Atlanta, GA 30333, USA
    J Microbiol Immunol Infect 38:244-54. 2005
    ..Thus, in mice and humans the inflammation associated with CCR5 function may predispose to development of complications of chlamydial infection, such as TFI...
  13. ncbi request reprint A novel recombinant multisubunit vaccine against Chlamydia
    Francis O Eko
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Immunol 173:3375-82. 2004
    ..These results support the operational theory that the ability of a vaccine to confer protective immunity against Chlamydia is a function of the level of Th1 response elicited...
  14. ncbi request reprint Developing effective delivery systems for Chlamydia vaccines
    Joseph U Igietseme
    National Center for Infectious Disease, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Curr Opin Mol Ther 6:182-94. 2004
    ..These efforts will likely culminate in an efficacious chlamydial vaccine in the near future...
  15. pmc Comparison of methods for detection of Chlamydia trachomatis and Neisseria gonorrhoeae using commercially available nucleic acid amplification tests and a liquid pap smear medium
    Emilia H Koumans
    Centers for Disease Control and Prevention Department of Pediatrics, Emory University, Atlanta, Georgia, USA
    J Clin Microbiol 41:1507-11. 2003
    ..trachomatis and N. gonorrhoeae from patient samples. Cytologic fluid shows promise for simultaneous screening for cytologic abnormalities and sexually transmitted infections...
  16. doi request reprint Effect of topical vaginal products on the detection of prostate-specific antigen, a biomarker of semen exposure, using ABAcards
    Margaret C Snead
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, and the Division of Scientific Resources, National Center for Emerging and Ζοοnotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA Electronic address
    Contraception 88:382-6. 2013
    ..We investigated this question using various dilutions of several vaginal products (lubricants and spermicides) and the Abacus ABAcard for PSA detection...
  17. doi request reprint Chlamydial infection in vitamin D receptor knockout mice is more intense and prolonged than in wild-type mice
    Qing He
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Steroid Biochem Mol Biol 135:7-14. 2013
    ..We conclude that the vitamin D endocrine system reduces the risk for prolonged chlamydial infections through regulation of several proteins and that LEI is involved in its anti-inflammatory activity...
  18. pmc Prevention of Chlamydia-induced infertility by inhibition of local caspase activity
    Joseph U Igietseme
    National Center for Emerging Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
    J Infect Dis 207:1095-104. 2013
    ..These results provide new insight into the molecular pathogenesis of TFI with significant implications for new strategies for treatment and prevention of chlamydial complications...
  19. doi request reprint Anogenital human papillomavirus in sexually abused and nonabused children: a multicenter study
    Elizabeth R Unger
    Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 128:e658-65. 2011
    ..To characterize the epidemiology of genital human papillomavirus (HPV) infection in children without previous consensual sexual activity, comparing HPV prevalence by certainty of child sexual abuse (CSA)...
  20. ncbi request reprint Incorporating adolescent females' perceptions of their partners' attitudes toward condoms into a model of female adolescent condom use
    Matthew Hogben
    Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Psychol Health Med 11:449-60. 2006
    ..The implications of these relations upon condom use correctness and consistency are discussed with respect to informing interventions, among other future research...
  21. pmc Chlamydia trachomatis serovars among strains isolated from members of rural indigenous communities and urban populations in Australia
    Claudiu I Bandea
    Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA
    J Clin Microbiol 46:355-6. 2008
    ..1%), D/Da (n = 4; 8.9%), G (n = 3; 6.7%), and K (n = 1; 2.2%). The distribution of C. trachomatis serovars among members of the indigenous rural and the urban Australian communities appears similar to that in other Western countries...
  22. ncbi request reprint Epidemiology of human papillomavirus infection and abnormal cytologic test results in an urban adolescent population
    Trudee A Tarkowski
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia, USA
    J Infect Dis 189:46-50. 2004
    ..0% had high- or low-grade squamous intraepithelial lesions) and were significantly associated with detection of HPV (P=.0001); however, most (51.6%) subjects with HPV had normal cytologic test results...
  23. ncbi request reprint Contemporary approaches to designing and evaluating vaccines against Chlamydia
    Joseph U Igietseme
    Molecular Pathogenesis Laboratory, National Center for Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Expert Rev Vaccines 2:129-46. 2003
    ....
  24. doi request reprint Chlamydia vaccines: recent developments and the role of adjuvants in future formulations
    Joseph U Igietseme
    National Center for Emerging Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop G 36, Atlanta, GA 30333, USA
    Expert Rev Vaccines 10:1585-96. 2011
    ....
  25. ncbi request reprint A pseudo-outbreak of Chlamydia trachomatis in a state residential facility: implications for diagnostic testing
    Deborah A Gust
    Division of STD Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 185:841-4. 2002
    ..For C. trachomatis screening tests, the need for confirmatory testing depends on individual patient considerations (including medical-legal implications) and prevalence of infection in the tested population...
  26. ncbi request reprint Antibody regulation of Tcell immunity: implications for vaccine strategies against intracellular pathogens
    Joseph U Igietseme
    Molecular Pathogenesis Laboratory, National Center for Infectious Disease, Centers for Disease Control and Prevention CDC, 1600 Clifton Road, Mailstop C17, Atlanta, GA 30333 USA
    Expert Rev Vaccines 3:23-34. 2004
    ..The immunobiological implications are discussed in the context of vaccine design, delivery and evaluation against intracellular microbial pathogens of bacteria, fungi and parasitic origin...
  27. pmc Newly characterized species-specific immunogenic Chlamydophila pneumoniae peptide reactive with murine monoclonal and human serum antibodies
    Eric L Marston
    Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Clin Diagn Lab Immunol 9:446-52. 2002
    ..The use of this novel peptide may allow investigators to establish standardized assays free from cross-reactive Chlamydia trachomatis and Chlamydophila psittaci epitopes and immunoreactivity...
  28. ncbi request reprint Chlamydia vaccines: strategies and status
    Joseph U Igietseme
    Microbiology and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, Georgia 30310, USA
    BioDrugs 16:19-35. 2002
    ..However, more research efforts and support are needed to achieve the worthy goal of protecting a significant number of the world's population from the devastating consequences of chlamydial invasion of the human mucosal epithelia...
  29. doi request reprint Optimal methods for collecting and storing vaginal specimens for prostate-specific antigen testing in research studies
    Maria F Gallo
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Mail Stop K 34, Atlanta, GA 30341 3724, USA
    Contraception 87:830-5. 2013
    ..Optimal methods for collecting and storing specimens for this testing have not been determined...
  30. ncbi request reprint Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens
    Terri Moore
    Morehouse School of Medicine, Atlanta, Georgia 30333, USA
    J Infect Dis 188:617-24. 2003
    ..Findings offer a paradigm in host defense wherein different effector components function indirectly to maximize the principal effector mechanism...
  31. ncbi request reprint Screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections--2002
    Robert E Johnson
    Division of Sexually Transmitted Diseases Prevention National Center for HIV, STD, and TB Prevention, CDC, USA
    MMWR Recomm Rep 51:1-38; quiz CE1-4. 2002
    ....
  32. ncbi request reprint Recombinant Vibrio cholerae ghosts as a delivery vehicle for vaccinating against Chlamydia trachomatis
    Francis O Eko
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr Atlanta, GA 30310, USA
    Vaccine 21:1694-703. 2003
    ..trachomatis infection. Altogether, the potency and relatively low production cost of rVCG offer a significant technical advantage as a chlamydial vaccine...
  33. ncbi request reprint Effect of specimen order on Chlamydia trachomatis and Neisseria gonorrhoeae test performance and adequacy of Papanicolaou smear
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue B3 North, Baltimore, MD 21224, USA
    J Pediatr Adolesc Gynecol 19:23-30. 2006
    ..To evaluate the effect of specimen collection order on the performance of diagnostic tests for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC), and the specimen adequacy of ThinPrep Papanicolaou (Pap) smears...
  34. pmc Impact of patient characteristics on performance of nucleic acid amplification tests and DNA probe for detection of Chlamydia trachomatis in women with genital infections
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Clin Microbiol 43:577-84. 2005
    ..These findings support expanded use of NAAT for screening and diagnosis of C. trachomatis in diverse clinical populations of women...
  35. pmc Population-based genetic and evolutionary analysis of Chlamydia trachomatis urogenital strain variation in the United States
    Kim Millman
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    J Bacteriol 186:2457-65. 2004
    ..Collectively, these data suggest a diverse evolutionary strategy for different serogroups of the organism...
  36. ncbi request reprint Population-based genetic epidemiologic analysis of Chlamydia trachomatis serotypes and lack of association between ompA polymorphisms and clinical phenotypes
    Kim Millman
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Microbes Infect 8:604-11. 2006
    ....
  37. ncbi request reprint Combination vaccines: design strategies and future trends
    Joseph U Igietseme
    Expert Rev Vaccines 5:739-45. 2006
  38. ncbi request reprint The natural history of untreated Chlamydia trachomatis infection in the interval between screening and returning for treatment
    William M Geisler
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Sex Transm Dis 35:119-23. 2008
    ..An improved understanding of chlamydial natural history may influence recommendations for elements of control efforts such as chlamydia screening frequency or time parameters for partner notification...