C B'Hymer

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Evaluation and comparison of urinary metabolic biomarkers of exposure for the jet fuel JP-8
    Clayton B'Hymer
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, U S Department of Health and Human Services, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Toxicol Environ Health A 75:661-72. 2012
  2. doi request reprint (2-methoxyethoxy)acetic acid: a urinary biomarker of exposure for jet fuel JP-8
    Clayton B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory, Cincinnati, OH 45226, USA
    Int Arch Occup Environ Health 85:413-20. 2012
  3. ncbi request reprint Validation of an HPLC-MS-MS method for the determination of urinary S-benzylmercapturic acid and S-phenylmercapturic acid
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory C 23, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr Sci 49:547-53. 2011
  4. ncbi request reprint Development of a gas chromatographic test for the quantitation of the biomarker 2-butoxyacetic acid in urine samples
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Taft Laboratory, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr Sci 45:422-7. 2007
  5. ncbi request reprint Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine
    Clayton B'Hymer
    US Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Cincinnati, OH, 45226, USA
    Anal Bioanal Chem 383:201-9. 2005
  6. ncbi request reprint Development of a gas chromatographic test for the quantification of the biomarker 3-bromopropionic acid in human urine
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory C 26, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 802:361-6. 2004
  7. ncbi request reprint Procedure for the quantification of the biomarker (2-methoxyethoxy)acetic acid in human urine samples
    C B'Hymer
    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 795:145-50. 2003
  8. ncbi request reprint 2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia
    K L Cheever
    DHHS PHS, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    Toxicol Lett 122:53-67. 2001
  9. ncbi request reprint Mutagenicity of N-OH-MOCA (4-amino-4'-hydroxylamino-bis-3,3'-dichlorodiphenylmethane) and PBQ (2-phenyl-1,4-benzoquinone) in human lymphoblastoid cells
    T M Reid
    Division of Biomedical and Behavioral Sciences, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    Toxicol Lett 95:205-10. 1998
  10. ncbi request reprint Development of a headspace gas chromatographic test for the quantification of 1- and 2-bromopropane in human urine
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 814:185-9. 2005

Collaborators

Detail Information

Publications14

  1. doi request reprint Evaluation and comparison of urinary metabolic biomarkers of exposure for the jet fuel JP-8
    Clayton B'Hymer
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, U S Department of Health and Human Services, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Toxicol Environ Health A 75:661-72. 2012
    ....
  2. doi request reprint (2-methoxyethoxy)acetic acid: a urinary biomarker of exposure for jet fuel JP-8
    Clayton B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory, Cincinnati, OH 45226, USA
    Int Arch Occup Environ Health 85:413-20. 2012
    ..JP-8 is a kerosene-based fuel containing different compounds that vary in the content of every batch/lot of fuel; thus, MEAA has the potential to be a more specific and a consistent quantitative biomarker for JP-8 exposure...
  3. ncbi request reprint Validation of an HPLC-MS-MS method for the determination of urinary S-benzylmercapturic acid and S-phenylmercapturic acid
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory C 23, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr Sci 49:547-53. 2011
    ..The limit of detection (LOD) is approximately 0.2 ng/mL for S-BMA and S-PMA. This data, other figures of merit and other factors, such as ion suppression of the electrospray ionization source, are discussed...
  4. ncbi request reprint Development of a gas chromatographic test for the quantitation of the biomarker 2-butoxyacetic acid in urine samples
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Taft Laboratory, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr Sci 45:422-7. 2007
    ..8% and less. The detection limit of this method ranges from 0.005 to 0.015 microg/mL equivalent level of 2-BAA in urine...
  5. ncbi request reprint Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine
    Clayton B'Hymer
    US Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Cincinnati, OH, 45226, USA
    Anal Bioanal Chem 383:201-9. 2005
    ..The limit of detection (LOD) and other figures of merit for both derivatization procedures will be discussed in detail. Applications of these analysis procedures are also discussed...
  6. ncbi request reprint Development of a gas chromatographic test for the quantification of the biomarker 3-bromopropionic acid in human urine
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory C 26, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 802:361-6. 2004
    ..D.S.) of 5.7% or less. The limit of detection (LOD) for the procedure was approximately 0.01microg/ml 3-BPA in urine. These data and other factors of the development and validation of this test method will be discussed...
  7. ncbi request reprint Procedure for the quantification of the biomarker (2-methoxyethoxy)acetic acid in human urine samples
    C B'Hymer
    Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 795:145-50. 2003
    ..6% and less. The limit of detection (LOD) for this procedure was found to range from 0.02 to 0.08 microg/ml equivalent levels of MEAA in urine. These data and other aspects of the validation of this procedure will be discussed...
  8. ncbi request reprint 2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia
    K L Cheever
    DHHS PHS, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    Toxicol Lett 122:53-67. 2001
    ..In comparison with urinary metabolites, the relatively slow elimination of adducted serum 2ME indicates that analysis of protein-bound concentrations could be a potential tool for long- term biomonitoring of worker exposure...
  9. ncbi request reprint Mutagenicity of N-OH-MOCA (4-amino-4'-hydroxylamino-bis-3,3'-dichlorodiphenylmethane) and PBQ (2-phenyl-1,4-benzoquinone) in human lymphoblastoid cells
    T M Reid
    Division of Biomedical and Behavioral Sciences, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    Toxicol Lett 95:205-10. 1998
    ..The induction of mutations at A:T sites by N-OH-MOCA is consistent with the type of DNA damage known to be produced by MOCA and provides a specific marker of genotoxic damage for exposed populations...
  10. ncbi request reprint Development of a headspace gas chromatographic test for the quantification of 1- and 2-bromopropane in human urine
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 814:185-9. 2005
    ..A recovery study of 1- and 2-BP from fortified urine stored in vials appropriate for field collection was also completed. These results and other factors of the development and validation of this test procedure will be discussed...
  11. doi request reprint Development of an HPLC-MS procedure for the quantification of N-acetyl-S-(n-propyl)-l-cysteine, the major urinary metabolite of 1-bromopropane in human urine
    K L Cheever
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 877:827-32. 2009
    ..4% or less. The limit of detection (LOD) for the procedure was approximately 0.01 microg/ml AcPrCys in urine. These data will be discussed as well as other factors of the development of this test procedure...
  12. ncbi request reprint Development of a residual solvent test for bulk alpha-phenyl-1-(2-phenylethyl)-piperine methanol using headspace sampling
    C B'Hymer
    University of Cincinnati, Mail Location 0172, Cincinnati, OH 45221 0172, USA
    J Chromatogr Sci 45:293-7. 2007
    ..These data and other aspects of the development of this test method are discussed...
  13. ncbi request reprint Evaluation of a headspace-GC method for residual solvents in a serotonin 5-HT3 antagonist compound
    C B'Hymer
    University of Cincinnati, Mail Location 0172, Cincinnati, OH 45221 0172, USA
    J Chromatogr Sci 46:369-74. 2008
    ..Toluene mean recovery of all spikes is 98% (w/w) of theory within the tested range (n = 6). These data and other facets of the development of this headspace method are discussed...
  14. ncbi request reprint Evaluation of a procedure for the simultaneous quantification of 4-ketocyclophosphamide, cyclophosphamide, and Ifosfamide in human urine
    C B'Hymer
    U S Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory C 23, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    J Chromatogr Sci 48:328-33. 2010
    ..4% or less. The limit of detection for this procedure is 1 ng/mL for 4-keto-CP, 0.1 ng/mL for CP, and 0.05 ng/mL for IF in urine...