Julu Bhatnagar

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Detection of West Nile virus in formalin-fixed, paraffin-embedded human tissues by RT-PCR: a useful adjunct to conventional tissue-based diagnostic methods
    Julu Bhatnagar
    Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Mailstop G32, Atlanta, GA 30333, United States
    J Clin Virol 38:106-11. 2007
  2. pmc Molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-PCR and sequencing: diagnostic and epidemiologic implications
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 86:335-40. 2012
  3. doi request reprint Localization of pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal influenza cases by in situ hybridization: new insights on virus replication and pathogenesis
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 56:232-7. 2013
  4. pmc Rapid, simultaneous detection of Clostridium sordellii and Clostridium perfringens in archived tissues by a novel PCR-based microsphere assay: diagnostic implications for pregnancy-associated toxic shock syndrome cases
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Infect Dis Obstet Gynecol 2012:972845. 2012
  5. ncbi request reprint Toxic shock associated with Clostridium sordellii and Clostridium perfringens after medical and spontaneous abortion
    Adam L Cohen
    Prevention and Response Branch, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Obstet Gynecol 110:1027-33. 2007
  6. pmc Diagnosis of influenza from respiratory autopsy tissues: detection of virus by real-time reverse transcription-PCR in 222 cases
    Amy M Denison
    Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Mol Diagn 13:123-8. 2011
  7. pmc 2009 pandemic influenza A (H1N1): pathology and pathogenesis of 100 fatal cases in the United States
    Wun Ju Shieh
    Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 32, Atlanta, GA 30333, USA
    Am J Pathol 177:166-75. 2010
  8. doi request reprint Neutrophilic bacterial meningitis: pathology and etiologic diagnosis of fatal cases
    Jeannette Guarner
    Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA, USA
    Mod Pathol 26:1076-85. 2013
  9. pmc Fatal Infectious Diseases during Pandemic (H1N1) 2009 Outbreak
    Dianna M Blau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Emerg Infect Dis 17:2069-70. 2011
  10. ncbi request reprint Histopathologic, immunohistochemical, and polymerase chain reaction assays in the study of cases with fatal sporadic myocarditis
    Jeannette Guarner
    Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Hum Pathol 38:1412-9. 2007

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Detection of West Nile virus in formalin-fixed, paraffin-embedded human tissues by RT-PCR: a useful adjunct to conventional tissue-based diagnostic methods
    Julu Bhatnagar
    Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Mailstop G32, Atlanta, GA 30333, United States
    J Clin Virol 38:106-11. 2007
    ....
  2. pmc Molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-PCR and sequencing: diagnostic and epidemiologic implications
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 86:335-40. 2012
    ..The IHC detected DENV antigens in 50 (40%) cases. The RT-PCR using FFPE tissue improves detection of DENV in fatal cases and provides sequence information useful for typing and epidemiologic studies...
  3. doi request reprint Localization of pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal influenza cases by in situ hybridization: new insights on virus replication and pathogenesis
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 56:232-7. 2013
    ..Although pH1N1 viral antigens have been demonstrated in various human tissues by immunohistochemistry (IHC), cellular localization of pH1N1 RNA in these tissues has largely remained uninvestigated...
  4. pmc Rapid, simultaneous detection of Clostridium sordellii and Clostridium perfringens in archived tissues by a novel PCR-based microsphere assay: diagnostic implications for pregnancy-associated toxic shock syndrome cases
    Julu Bhatnagar
    Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Infect Dis Obstet Gynecol 2012:972845. 2012
    ..The microsphere assay is a rapid, specific, and cost-effective method for the diagnosis of CTS and offers the advantage of simultaneous testing for C. sordellii and C. perfringens in FFPE tissues using a limited amount of DNA...
  5. ncbi request reprint Toxic shock associated with Clostridium sordellii and Clostridium perfringens after medical and spontaneous abortion
    Adam L Cohen
    Prevention and Response Branch, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Obstet Gynecol 110:1027-33. 2007
    ..To better understand the risk of fatal toxic shock caused by Clostridium sordellii in women who had a recent medical abortion with mifepristone and misoprostol...
  6. pmc Diagnosis of influenza from respiratory autopsy tissues: detection of virus by real-time reverse transcription-PCR in 222 cases
    Amy M Denison
    Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Mol Diagn 13:123-8. 2011
    ..We also determined that testing of all available respiratory tissues is critical for optimal detection of influenza virus in postmortem tissues...
  7. pmc 2009 pandemic influenza A (H1N1): pathology and pathogenesis of 100 fatal cases in the United States
    Wun Ju Shieh
    Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 32, Atlanta, GA 30333, USA
    Am J Pathol 177:166-75. 2010
    ..Underlying medical conditions and bacterial co-infections contributed to the fatal outcome of this infection. More studies are needed to understand the multifactorial pathogenesis of this infection...
  8. doi request reprint Neutrophilic bacterial meningitis: pathology and etiologic diagnosis of fatal cases
    Jeannette Guarner
    Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA, USA
    Mod Pathol 26:1076-85. 2013
    ..In summary, our study shows that S. pneumoniae continues to be the most frequent cause of fatal neutrophilic bacterial meningitis followed by N. meningitidis, both vaccine preventable diseases. ..
  9. pmc Fatal Infectious Diseases during Pandemic (H1N1) 2009 Outbreak
    Dianna M Blau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Emerg Infect Dis 17:2069-70. 2011
    ....
  10. ncbi request reprint Histopathologic, immunohistochemical, and polymerase chain reaction assays in the study of cases with fatal sporadic myocarditis
    Jeannette Guarner
    Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Hum Pathol 38:1412-9. 2007
    ..Accurately identifying an infectious agent is the foundation for clinical and public health interventions. Despite using multiple diagnostic methods, an organism could only be detected in a small proportion of sporadic myocarditis cases...
  11. doi request reprint Correlation of the detection of Clostridium difficile toxins in stools and presence of the clostridia in tissues of children
    Jeannette Guarner
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA
    Hum Pathol 41:1586-92. 2010
    ..Clostridial antigens were only observed with histopathologic evidence of pseudomembranes...
  12. ncbi request reprint Fatal hemorrhagic fever caused by West Nile virus in the United States
    Christopher D Paddock
    Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Infect Dis 42:1527-35. 2006
    ..We describe a case of fulminant WNV infection in a 59-year-old Florida man who died following a brief illness that resembled hemorrhagic disease caused by Rickettsia reckettsii, dengue virus or yellow fever virus...
  13. ncbi request reprint Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion
    Marc Fischer
    Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 353:2352-60. 2005
    ..These cases indicate the need for physician awareness of this syndrome and for further study of its association with medical abortion...
  14. pmc Development and evaluation of a novel multiplex PCR technology for molecular differential detection of bacterial respiratory disease pathogens
    Robert Benson
    CDC, Atlanta, GA 30333, USA
    J Clin Microbiol 46:2074-7. 2008
    ..The ResPlex I assay is somewhat less sensitive than real-time PCR assays but offers the advantage of multiple assays in a single reaction...
  15. doi request reprint Clostridium difficile-associated diarrhea: an emerging threat to pregnant women
    Nadine G Rouphael
    Division of Bacterial Diseases, Epidemic Intelligence Service Field Assignments Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Am J Obstet Gynecol 198:635.e1-6. 2008
    ..To estimate if Clostridium difficile-associated disease (CDAD) is increasing in peripartum women...
  16. pmc Cell culture and electron microscopy for identifying viruses in diseases of unknown cause
    Cynthia S Goldsmith
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G32, Atlanta, GA 30329, USA
    Emerg Infect Dis 19:886-91. 2013
    ..These cases illustrate the importance of the techniques of cell culture and electron microscopy in pathogen identification and recognition of emerging diseases...
  17. ncbi request reprint Persistent neuroinvasive West Nile virus infection in an immunocompromised patient
    Robert G Penn
    Department of Epidemiology, Methodist Hospital, Omaha, Nebraska, USA
    Clin Infect Dis 42:680-3. 2006
    ..This patient's case raises important issues related to the diagnosis, pathogenesis, and possible treatment of persistent WNV infection...