J T Bernert

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight
    Joe M Braun
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599 7435, USA
    Environ Health 9:53. 2010
  2. ncbi request reprint Development and validation of sensitive method for determination of serum cotinine in smokers and nonsmokers by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry
    J T Bernert
    Division of Environmental Health Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Chem 43:2281-91. 1997
  3. doi request reprint Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U.S. population from secondhand smoke exposure
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Cancer Epidemiol Biomarkers Prev 19:2969-77. 2010
  4. pmc Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Nicotine Tob Res 11:1458-66. 2009
  5. doi request reprint Increases in tobacco exposure biomarkers measured in non-smokers exposed to sidestream cigarette smoke under controlled conditions
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Biomarkers 14:82-93. 2009
  6. ncbi request reprint Time course of nicotine and cotinine incorporation into samples of nonsmokers' beard hair following a single dose of nicotine polacrilex
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F 47, Atlanta, GA 30341, USA
    J Anal Toxicol 35:1-7. 2011
  7. ncbi request reprint Calculation of serum "total lipid" concentrations for the adjustment of persistent organohalogen toxicant measurements in human samples
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE Atlanta, Georgia 30341, United States
    Chemosphere 68:824-31. 2007
  8. ncbi request reprint Use of continine immunoassay test strips for preclassifying urine samples from smokers and nonsmokers prior to analysis by LC-MS-MS
    John T Bernert
    Tobacco Exposure Biomarkers Laboratory, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA 30341, USA
    J Anal Toxicol 29:814-8. 2005
  9. ncbi request reprint Urinary tobacco-specific nitrosamines and 4-aminobiphenyl hemoglobin adducts measured in smokers of either regular or light cigarettes
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Nicotine Tob Res 7:729-38. 2005
  10. ncbi request reprint Analysis of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine by extraction on a molecularly imprinted polymer column and liquid chromatography/atmospheric pressure ionization tandem mass spectrometry
    Yang Xia
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Anal Chem 77:7639-45. 2005

Collaborators

Detail Information

Publications32

  1. pmc A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight
    Joe M Braun
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599 7435, USA
    Environ Health 9:53. 2010
    ..The evaluation of infant meconium as a cumulative matrix of prenatal toxicant exposure requires comparison to established biomarkers of prenatal exposure...
  2. ncbi request reprint Development and validation of sensitive method for determination of serum cotinine in smokers and nonsmokers by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry
    J T Bernert
    Division of Environmental Health Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Chem 43:2281-91. 1997
    ..This method has been applied to the analysis of cotinine in serum samples collected as part of the Third National Health and Nutrition Examination Survey (NHANES III)...
  3. doi request reprint Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U.S. population from secondhand smoke exposure
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Cancer Epidemiol Biomarkers Prev 19:2969-77. 2010
    ..We have measured total NNAL in the U.S. population of tobacco users and nonsmokers exposed to secondhand smoke...
  4. pmc Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Nicotine Tob Res 11:1458-66. 2009
    ..Among nonsmokers exposed to SHS, the concentration of cotinine in blood can be quite low, and extensive variability in these measurements has been reported in the past...
  5. doi request reprint Increases in tobacco exposure biomarkers measured in non-smokers exposed to sidestream cigarette smoke under controlled conditions
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Biomarkers 14:82-93. 2009
    ....
  6. ncbi request reprint Time course of nicotine and cotinine incorporation into samples of nonsmokers' beard hair following a single dose of nicotine polacrilex
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F 47, Atlanta, GA 30341, USA
    J Anal Toxicol 35:1-7. 2011
    ..However, both the time-course and extent of deposition of these analytes in beard hair in this study differed from the results reported previously from a similar evaluation...
  7. ncbi request reprint Calculation of serum "total lipid" concentrations for the adjustment of persistent organohalogen toxicant measurements in human samples
    John T Bernert
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE Atlanta, Georgia 30341, United States
    Chemosphere 68:824-31. 2007
    ....
  8. ncbi request reprint Use of continine immunoassay test strips for preclassifying urine samples from smokers and nonsmokers prior to analysis by LC-MS-MS
    John T Bernert
    Tobacco Exposure Biomarkers Laboratory, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA 30341, USA
    J Anal Toxicol 29:814-8. 2005
    ..However, the relatively high cost of the strips may be a limiting factor...
  9. ncbi request reprint Urinary tobacco-specific nitrosamines and 4-aminobiphenyl hemoglobin adducts measured in smokers of either regular or light cigarettes
    John T Bernert
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Nicotine Tob Res 7:729-38. 2005
    ..Thus the concentrations of the carcinogen biomarkers NNAL and 4-ABP in the smokers who regularly smoked light cigarettes were essentially the same as those in the smokers who chose regular cigarettes...
  10. ncbi request reprint Analysis of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine by extraction on a molecularly imprinted polymer column and liquid chromatography/atmospheric pressure ionization tandem mass spectrometry
    Yang Xia
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Anal Chem 77:7639-45. 2005
    ....
  11. doi request reprint Estimates of nondisclosure of cigarette smoking among pregnant and nonpregnant women of reproductive age in the United States
    Patricia M Dietz
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Am J Epidemiol 173:355-9. 2011
    ..Studies and surveillance systems that rely on self-reported smoking status are subject to underestimation of smoking prevalence, especially among pregnant women, and underreporting may vary by demographic characteristics...
  12. doi request reprint Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008
    Yang Xia
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Biomarkers 16:112-9. 2011
    ..001). In addition to addressing current NNK exposure levels, these results will form a baseline for future estimates of tobacco users' exposure to this carcinogen...
  13. ncbi request reprint Stability of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine samples stored at various temperatures
    Yang Xia
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, Georgia 30341, USA
    J Anal Toxicol 34:411-5. 2010
    ..These results suggest that valid NNAL concentrations can be measured in frozen urine samples that have been stored for an extended period of time prior to analysis...
  14. ncbi request reprint Analysis of 4-aminobiphenyl hemoglobin adducts in smokers and nonsmokers by pseudo capillary on-column gas chromatography- tandem mass spectrometry
    Tiffany H Seyler
    Emergency Response and Air Toxicants Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    J Anal Toxicol 34:304-11. 2010
    ..Our study shows that 4-aminobiphenyl Hb adducts remain the preferred biomarker for identifying people exposed to aromatic amines from tobacco smoke...
  15. doi request reprint Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers
    David L Ashley
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Cancer Epidemiol Biomarkers Prev 19:1389-98. 2010
    ..Previous studies have shown significant global differences in the levels of TSNAs in cigarette smoke because of the variation in tobacco blending and curing practices around the world...
  16. doi request reprint Effect of body mass index and total blood volume on serum cotinine levels among cigarette smokers: NHANES 1999-2008
    Ram B Jain
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, United States
    Clin Chim Acta 411:1063-8. 2010
    ..Body mass index (BMI) and total blood volume are not always considered as variables that affect serum cotinine concentrations...
  17. doi request reprint Non-cigarette tobacco use among women and adverse pregnancy outcomes
    Lucinda J England
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30030, USA
    Acta Obstet Gynecol Scand 89:454-64. 2010
    ..We highlight research gaps and provide recommendations for a global research agenda...
  18. ncbi request reprint Sequelae of severe respiratory syncytial virus infection in infancy and early childhood among Alaska Native children
    Rosalyn J Singleton
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Arctic Investigations Program Anchorage, Anchorage, Alaska 99508, USA
    Pediatrics 112:285-90. 2003
    ....
  19. ncbi request reprint Simultaneous determination of multiple drugs of abuse and relevant metabolites in urine by LC-MS-MS
    June Feng
    Emergency Response and Air Toxicants Branch, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, Georgia 30341, USA
    J Anal Toxicol 31:359-68. 2007
    ..To evaluate method performance, 108 urine samples were collected anonymously and tested for the presence of these drugs...
  20. ncbi request reprint Assessment of the relation between biomarkers for smoking and biomarkers for acrylamide exposure in humans
    Hubert W Vesper
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Northeast MS F 25, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 16:2471-8. 2007
    ..The findings suggest that tobacco smoke exposure in individuals with PC values of <1 ng/mL has only a minimal effect on HbAA and HbGA...
  21. pmc Trends in the exposure of nonsmokers in the U.S. population to secondhand smoke: 1988-2002
    James L Pirkle
    Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Environ Health Perspect 114:853-8. 2006
    ..Our findings suggest that recent public health efforts to reduce such exposures have had an important effect, although children and non-Hispanic black nonsmokers show relatively higher levels of serum cotinine...
  22. ncbi request reprint Analysis of 13 fentanils, including sufentanil and carfentanil, in human urine by liquid chromatography-atmospheric-pressure ionization-tandem mass spectrometry
    Lanqing Wang
    Emergency Response and Air Toxicants Branch, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F 47, Atlanta, Georgia 30341, USA
    J Anal Toxicol 30:335-41. 2006
    ..This method should be useful for the rapid and sensitive screening of human urine samples for a number of fentanils and their metabolites as indicators of exposure...
  23. pmc Molecular evidence of an interaction between prenatal environmental exposures and birth outcomes in a multiethnic population
    Frederica P Perera
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, 60 Haven Avenue B 109, New York, NY 10032, USA
    Environ Health Perspect 112:626-30. 2004
    ..This study provides evidence that combined exposure to environmental pollutants at levels currently encountered in New York City adversely affects fetal development...
  24. ncbi request reprint Carcinogen exposure during short-term switching from regular to "light" cigarettes
    Neal L Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California at San Francisco, Box 1220, San Francisco, CA 94143 1220, USA
    Cancer Epidemiol Biomarkers Prev 14:1376-83. 2005
    ....
  25. ncbi request reprint Correlating atmospheric and biological markers in studies of secondhand tobacco smoke exposure and dose in children and adults
    James Repace
    Tufts University School of Medicine, and Repace Associates Inc, 101 Felicia Lane, Bowie, MD 20720, USA
    J Occup Environ Med 48:181-94. 2006
    ..We sought to directly compare secondhand smoke (SHS) atmospheric markers to each other and to SHS dosimetric biomarkers, permitting intercomparison of clinical and atmospheric studies...
  26. ncbi request reprint Analysis of cotinine in dried blood spots by LC APCI tandem mass spectrometry
    Connie S Sosnoff
    Clin Chim Acta 388:228-9. 2008
  27. ncbi request reprint High levels of transdermal nicotine exposure produce green tobacco sickness in Latino farmworkers
    Thomas A Arcury
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Nicotine Tob Res 5:315-21. 2003
    ..Treatment of GTS must address nicotine poisoning. GTS affects laborers with limited resources. Research must disclose the extent of this occupational illness and investigate ways to prevent it...
  28. ncbi request reprint Environmental tobacco smoke and pregnancy outcome
    Martin Kharrazi
    Genetic Disease Branch, California Department of Health Services, Richmond, California 94804, USA
    Epidemiology 15:660-70. 2004
    ..However, the threshold and magnitude of that effect is uncertain. We aimed to determine the magnitude and shape of the relations between ETS and various adverse pregnancy outcomes using a highly sensitive biochemical assay...
  29. ncbi request reprint Prenatal smoking and alterations in newborn heart rate during transition
    Jan Sherman
    University of California San Francisco, School of Nursing, Department of Family Health Care, USA
    J Obstet Gynecol Neonatal Nurs 31:680-7. 2002
    ..To evaluate the effects of prenatal cigarette smoke exposure on newborn heart rate following the physiologic challenge of birth...
  30. ncbi request reprint Exposure to environmental tobacco smoke in pregnant women: the association between self-report and serum cotinine
    Gerald N DeLorenze
    Public Health Institute, Berkeley, California, USA
    Environ Res 90:21-32. 2002
    ..quot; Since there is recent evidence that low levels of ETS exposure result in unfavorable pregnancy outcomes, these studies have underestimated the effect of ETS...
  31. ncbi request reprint Changes in nicotine intake and cigarette use over time in two nationally representative cross-sectional samples of smokers
    RICHARD J O'CONNOR
    Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Am J Epidemiol 164:750-9. 2006
    ..In addition, these data are inconsistent with the hypothesis that the remaining population of smokers is becoming more dependent on nicotine over time...
  32. ncbi request reprint Measuring secondhand smoke exposure in children: an ecological measurement approach
    Georg E Matt
    Department of Psychology, San Diego State University, San Diego, CA 92182 4611, USA
    J Pediatr Psychol 33:156-75. 2008
    ..Behavioral, environmental, and biological measures of secondhand smoke (SHS) exposure are reviewed with special consideration of medically at-risk children...