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Genomes and GenesSpecies | Scott W BeardenSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Publications
Recent findings regarding maintenance of enzootic variants of Yersinia pestis in sylvatic reservoirs and their significance in the evolution of epidemic plagueScott W Bearden
Division of Vector Borne Infectious Diseases, Bacterial Diseases Branch, Centers for Disease Control and Prevention, Foothills Campus, Fort Collins, Colorado 80521, USA
Vector Borne Zoonotic Dis 10:85-92. 2010..The implications of these findings for the distribution and ecology of Y. pestis could be significant...
Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogsAryn P Wilder
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
Ecohealth 5:205-12. 2008..tuberculata cynomuris abundance, and in September-October when O. hirsuta is common. Our findings may be useful in determining the timing of insecticidal dusting to slow plague transmission in black-tailed prairie dogs...- Effects of temperature on the transmission of Yersinia Pestis by the flea, Xenopsylla Cheopis, in the late phase periodAnna M Schotthoefer
Bacterial Diseases Branch, Division of Vector Borne Diseases, National Center for Emerging and Zoonotic, Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
Parasit Vectors 4:191. 2011..i.), and every 3-4 days thereafter until day 14 p.i. for fleas held at 10°C, or 28 days p.i. for fleas held at 23-30°C. Transmission was confirmed using Y. pestis-specific antigen or antibody detection assays on mouse tissues... - Oropsylla hirsuta (Siphonaptera: Ceratophyllidae) can support plague epizootics in black-tailed prairie dogs (Cynomys ludovicianus) by early-phase transmission of Yersinia pestisAryn P Wilder
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
Vector Borne Zoonotic Dis 8:359-67. 2008..Shared burrows and sociality of prairie dogs could lead to accumulation of fleas when host population is reduced as a result of the disease, enabling epizootic spread of plague among prairie dogs... - Biofilm formation is not required for early-phase transmission of Yersinia pestisSara M Vetter
Bacterial Diseases Branch, Division of Vector Borne Diseases, National Center for Enteric and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, CO 80521, USA
Microbiology 156:2216-25. 2010..pestis in our EPT model, although biofilm overproduction inhibited efficient EPT. Our results also indicate, however, that biofilms may play a role in infection persistence in the flea... 
Effects of temperature on early-phase transmission of Yersina pestis by the flea, Xenopsylla cheopisAnna M Schotthoefer
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Emerging and Zoonotic, Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
J Med Entomol 48:411-7. 2011..By contrast, transmission may be delayed or inhibited at low temperatures, indicating that epizootic spread of Y. pestis by X. cheopis via early-phase transmission is unlikely during colder periods of the year...- Attenuated enzootic (pestoides) isolates of Yersinia pestis express active aspartaseScott W Bearden
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Bacterial Diseases Branch, Fort Collins, CO 80521, USA
Microbiology 155:198-209. 2009..In this context, aspA of the recently described attenuated enzootic microtus biovar encodes active valine at position 363, further indicating that functional AspA is a biomarker for avirulence of Y. pestis in man... - Early-phase transmission of Yersinia pestis by unblocked Xenopsylla cheopis (Siphonaptera: Pulicidae) is as efficient as transmission by blocked fleasRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Enteric and Vector Borne Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, USA
J Med Entomol 44:678-82. 2007..Furthermore, transmission efficiency seemed to remain constant until block formation, resulting in an infectious period considerably longer than previously thought... - Source of host blood affects prevalence of infection and bacterial loads of Yersinia pestis in fleasRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Enteric and Vector Borne Diseases, Centers for Disease Control and Prevention, P O Box 2087, Fort Collins, CO 80522, USA
J Med Entomol 45:933-8. 2008..pestis (A1122). Implications of the results for rate of spread of Y. pestis in naturally infected host populations are discussed... - Temporal dynamics of early-phase transmission of Yersinia pestis by unblocked fleas: secondary infectious feeds prolong efficient transmission by Oropsylla montana (Siphonaptera: Ceratophyllidae)Rebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, USA
J Med Entomol 44:672-7. 2007..Our data indicated that the duration of time over which O. montana reliably transmitted plague bacteria was longer than previously thought, and this may help to explain rapid rates of epizootic spread... - Early-phase transmission of Yersinia pestis by cat fleas (Ctenocephalides felis) and their potential role as vectors in a plague-endemic region of UgandaRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Enteric and Vector Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 78:949-56. 2008..Plague control programs in this region should remain focused on reducing rat flea populations, although our findings imply that cat fleas should not be ignored by these programs as they could play a significant role as secondary vectors... - Development of a real-time quantitative PCR assay to enumerate Yersinia pestis in fleasElizabeth S Gabitzsch
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado 80521, USA
Am J Trop Med Hyg 79:99-101. 2008..pestis and as little as 300 bacteria in infected flea triturates. This qPCR assay enables rapid enumeration of Y. pestis bacterium in laboratory-infected fleas when compared with conventional serial dilution plating... - Laboratory maintenance and characterization of Yersinia pestisScott W Bearden
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado, USA
Curr Protoc Microbiol . 2008..Strain-dependent requirements for different Biosafety Level containments are also discussed... - Detection of viable Yersinia pestis by fluorescence in situ hybridization using peptide nucleic acid probesJohn H Kenny
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, United States
J Microbiol Methods 75:293-301. 2008..The PNA-FISH assays described in this study allow for the sensitive and specific detection of viable Y. pestis bacteria in a timely manner... - Early-phase transmission of Yersinia pestis by unblocked fleas as a mechanism explaining rapidly spreading plague epizooticsRebecca J Eisen
Bacterial Diseases Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, USA
Proc Natl Acad Sci U S A 103:15380-5. 2006..pestis is transmitted during rapidly spreading epizootics and epidemics, including, perhaps, the Black Death...