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Species | L J AndersonSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Respiratory syncytial virus vaccines for otitis mediaL J Anderson
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Mailstop A34, 1600 Clifton Road, Atlanta, GA 30333, USA
Vaccine 19:S59-65. 2000..e. in older children at high risk for RSV disease and the elderly. An effective RSV vaccine for the infant and young child could markedly decrease otitis media disease...
Mumps epidemiology and immunity: the anatomy of a modern epidemicLarry J Anderson
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 27:S75-9. 2008..The reason for this mumps outbreak is not clear but probably results from multiple factors contributing to an overall increase in susceptibility and/or transmission...
Update on SARS research and other possibly zoonotic coronavirusesLarry J Anderson
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Int J Antimicrob Agents 36:S21-5. 2010..Studies since the SARS outbreak suggest that many novel viruses exist in animals and some, but probably not many, will present a risk to humans...
Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c miceR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 73:7099-107. 1999..These data show that G and/or SH protein has a marked impact on the inflammatory and innate immune response to RSV infection...
Respiratory syncytial virus infection and G and/or SH protein expression contribute to substance P, which mediates inflammation and enhanced pulmonary disease in BALB/c miceR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 74:1614-22. 2000..These data suggest that SP may be an important contributor to the inflammatory response to RSV infection and that anti-SP F(ab)(2) antibodies might be used to ameliorate RSV-associated disease...
TH(1)- and TH(2)-TYPE cytokine expression by activated t lymphocytes from the lung and spleen during the inflammatory response to respiratory syncytial virusR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
Cytokine 12:801-7. 2000..These data demonstrate that RSV-induced pulmonary inflammation involves extensive cellular activation and cytokine expression, particularly by CD54(+)and CD102(+)lymphocytes in the lung...
CD40 ligand (CD154) enhances the Th1 and antibody responses to respiratory syncytial virus in the BALB/c mouseR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Immunol 164:5913-21. 2000..These data suggest that CD40L may have the adjuvant properties needed to optimize the safety and efficacy of RSV vaccines...
Neutralizing anti-F glycoprotein and anti-substance P antibody treatment effectively reduces infection and inflammation associated with respiratory syncytial virus infectionLia M Haynes
Respiratory and Enteric Virus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 76:6873-81. 2002..The results suggest that combined anti-viral and anti-SP antibody treatment may be effective in treating RSV disease...
Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteinsRalph A Tripp
National Centers for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Mailstop G-09, Atlanta, GA 30333, USA
J Virol Methods 128:21-8. 2005..The mAbs characterized should prove useful for developing SARS-CoV diagnostic assays and for studying the biology of infection and pathogenesis of disease...
CD40 ligand (CD154) improves the durability of respiratory syncytial virus DNA vaccination in BALB/c miceJennifer L Harcourt
National Centers for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, 1600 Clifton Road NE, Mailstop G-09, Atlanta, GA 30333, USA
Vaccine 21:2964-79. 2003..The addition of CD40L to DNA vaccines encoding the F glycoprotein enhanced virus clearance and some aspects of the immune response to RSV challenge, suggesting that CD40L may enhance the durability of RSV DNA vaccines...
Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouseR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 74:6227-9. 2000..The results suggest that RSV G and/or SH proteins inhibit early MIP-1alpha, MIP-1beta, MIP-2, MCP-1, and IP-10 mRNA expression. TCA-3 mRNA expression was found to be increased during PIV-3 infection...
Respiratory syncytial virus outbreak on American Samoa. Evaluation of risk factorsE B Hayes
Division of Viral Diseases, Centers for Disease Control, Atlanta
Am J Dis Child 143:316-21. 1989..Our study documents the involvement of RSV in an outbreak of severe LRI among infants in a tropical area and further suggests that exposure to cigarette smoke is a risk factor for LRI infants...
Characterization of human metapneumoviruses isolated from patients in North AmericaTeresa C T Peret
Respiratory Virus Section, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
J Infect Dis 185:1660-3. 2002..These findings support a previous finding that HMPV is a human respiratory pathogen that merits further study...
A novel coronavirus associated with severe acute respiratory syndromeThomas G Ksiazek
Special Pathogens Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 348:1953-66. 2003..Because of the death of Dr. Carlo Urbani, we propose that our first isolate be named the Urbani strain of SARS-associated coronavirus...
Substantial variability in community respiratory syncytial virus season timingJames A Mullins
Repiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 22:857-62. 2003..Local RSV data are needed to accurately define the onset and offset of RSV seasons and to refine timing of passive immune prophylaxis therapy recommendations...
Lower respiratory tract infections among american Indian and Alaska Native children and the general population of U.S. ChildrenAngela J Peck
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Atlanta, GA, USA
Pediatr Infect Dis J 24:342-51. 2005..Strategies to reduce LRTI hospitalizations and outpatient visits are warranted for all infants, but the greatest potential impact would be among AI/AN infants...
Antibody enhancement of respiratory syncytial virus stimulation of leukotriene production by a macrophagelike cell lineG A Ananaba
Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta, Georgia 30333
J Virol 65:5052-60. 1991..This phenomenon could contribute to diseases, such as RSV bronchiolitis, that appear to be caused by an interaction between the virus (or antigen) and host immunity...
Sequence polymorphism of the predicted human metapneumovirus G glycoproteinTeresa C T Peret
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Gen Virol 85:679-86. 2004....
Prophylactic treatment with a G glycoprotein monoclonal antibody reduces pulmonary inflammation in respiratory syncytial virus (RSV)-challenged naive and formalin-inactivated RSV-immunized BALB/c miceGertrud U Radu
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G 18, Atlanta, GA 30333, USA
J Virol 84:9632-6. 2010..It is possible that antibodies with similar reactivities might prevent enhanced disease and improve the safety of nonlive virus vaccines...
Pulmonary delivery of respiratory syncytial virus DNA vaccines using macroaggregated albumin particlesJennifer L Harcourt
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, National Center for Infectious Diseases, 1600 Clifton Road NE, Mailstop G-09, Atlanta, GA 30333, USA
Vaccine 22:2248-60. 2004..This study shows that MAA may be a useful carrier for RSV DNA vaccines...
Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responsesJennifer Harcourt
Division of Viral and Rickettsial Diseases, Viral and Enteric Virus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Immunol 176:1600-8. 2006..In addition, we show that CX3CR1+ cells constitute a major component of the cytotoxic response to RSV infection. These results suggest that G protein and the G protein CX3C motif reduce the antiviral T cell response to RSV infection...
Treatment with respiratory syncytial virus G glycoprotein monoclonal antibody or F(ab')2 components mediates reduced pulmonary inflammation in miceCongrong Miao
National Centers for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Gen Virol 90:1119-23. 2009..Thus, this mAb has two independent actions that could facilitate treatment and/or prevention of RSV infection by reducing both virus replication and virus-induced pulmonary inflammation...
Possible transmission of parvovirus B19 from intravenous immune globulinD D Erdman
Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
J Med Virol 53:233-6. 1997..If true, this finding suggests that investigators must be careful in linking B19 infection to disease based on detection of B19 DNA in persons who have received multiple unit blood products...
Bronchiolitis-associated hospitalizations among US children, 1980-1996D K Shay
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 282:1440-6. 1999..Few national estimates exist of the hospitalizations attributable to RSV, and recent advances in prophylaxis warrant an update of these estimates...
Bronchiolitis-associated hospitalizations among American Indian and Alaska Native childrenS A Lowther
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 19:11-7. 2000....
CD4(+) T cell frequencies and Th1/Th2 cytokine patterns expressed in the acute and memory response to respiratory syncytial virus I-E(d)-restricted peptidesR A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Atlanta, Georgia 30333, USA
Cell Immunol 207:59-71. 2001..The frequency and breadth of cytokine expression by I-E(d)-restricted CD4(+) T cells to peptide stimulation was diminished in the memory response...
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virusL M Haynes
Respiratory and Enteric Virus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 75:10730-7. 2001..These findings suggest that Toll signaling pathways have an important role in innate immunity to RSV...
Severe acute respiratory syndrome coronavirus on hospital surfacesScott F Dowell
International Emerging Infections Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 39:652-7. 2004..Health care workers continued to contract severe acute respiratory syndrome (SARS), even after barrier precautions were widely implemented...
Respiratory syncytial virus hospitalizations among American Indian and Alaska Native infants and the general United States infant populationRobert C Holman
Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, MS A-39, Atlanta, GA 30333, USA
Pediatrics 114:e437-44. 2004..Development of vaccines, antiviral agents, and other strategies to prevent RSV disease could yield substantial public health benefits...
Two outbreaks of severe respiratory disease in nursing homes associated with rhinovirusLauri A Hicks
Respiratory Diseases Branch, National Center for Infectious Diseases, Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Am Geriatr Soc 54:284-9. 2006..To characterize illness and identify the etiology for two nursing home outbreaks of respiratory illness...
Infectious disease hospitalizations among American Indian and Alaska native infantsRobert C Holman
Division of Viral and Rickettsial Diseases (DVRD, National Center for Infectious Diseases (NCID, Centers for Disease Control and Prevention (CDC, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
Pediatrics 111:E176-82. 2003..CONCLUSIONS: Although infectious disease hospitalization rates for AI/AN infants have declined, AI/AN infants continue to have a higher infectious disease burden than the general US infant population...
Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirusShannon L Emery
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 10:311-6. 2004..The real-time RT-PCR assay was more sensitive than a conventional RT-PCR assay or culture isolation and proved suitable to detect SARS-CoV in clinical specimens. Application of this assay will aid in diagnosing SARS-CoV infection...
Genetic diversity of human parvovirus B19: sequence analysis of the VP1/VP2 gene from multiple isolatesD D Erdman
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Gen Virol 77:2767-74. 1996..These data suggest that geographically defined genetic lineages of B19 may exist and that no particular B19 genotype was associated with a particular clinical outcome...
Pathologic studies of fatal cases in outbreak of hand, foot, and mouth disease, TaiwanW J Shieh
Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop G32, Atlanta, GA 30333, USA
Emerg Infect Dis 7:146-8. 2001..Pathologic studies of two fatal cases with similar clinical features revealed two different causative agents, emphasizing the need for postmortem examinations and modern pathologic techniques in an outbreak investigation...
A cohort study of health care workers to assess nosocomial transmissibility of Nipah virus, Malaysia, 1999A W Mounts
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
J Infect Dis 183:810-3. 2001....
Trends in encephalitis-associated deaths in the United StatesN Khetsuriani
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Atlanta, GA 30333, USA
Epidemiol Infect 135:583-91. 2007..HIV infection was largely responsible for the lack of overall decline in the considerable mortality associated with encephalitis in the United States during 1979-1998...
Vitamin A therapy for children with respiratory syncytial virus infection: a multicenter trial in the United StatesJ S Bresee
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
Pediatr Infect Dis J 15:777-82. 1996..High dose vitamin A therapy is effective in reducing morbidity and mortality associated with measles infection. Children with acute respiratory syncytial virus (RSV) infection have low serum vitamin A concentrations...
Molecular characterization of Nipah virus, a newly emergent paramyxovirusB H Harcourt
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 271:334-49. 2000..Phylogenetic analysis demonstrated that although HV and NV are closely related, they are clearly distinct from any of the established genera within the Paramyxoviridae and should be considered a new genus...
Seasonal trends of human parainfluenza viral infections: United States, 1990-2004Alicia M Fry
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
Clin Infect Dis 43:1016-22. 2006..Human parainfluenza viruses (HPIVs) are important causes of upper and lower respiratory tract illness among children and adults...
Detection of novel SARS-like and other coronaviruses in bats from KenyaSuxiang Tong
Gastroenteritis and Respiratory Virus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 15:482-5. 2009..The sequence diversity suggests that bats are well-established reservoirs for and likely sources of coronaviruses for many species, including humans...
GeneScan reverse transcription-PCR assay for detection of six common respiratory viruses in young children hospitalized with acute respiratory illnessDean D Erdman
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:4298-303. 2003..We conclude that the GeneScan RT-PCR panel can markedly improve detection of acute respiratory virus infections in young children...
SARS-associated coronavirus transmission, United StatesElmira T Isakbaeva
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:225-31. 2004..The data suggest that SARS-CoV is not always transmitted efficiently. Routine collection and testing of stool and sputum specimens of probable SARS case-patients may help the early detection of SARS-CoV infection...
SARS surveillance during emergency public health response, United States, March-July 2003Stephanie J Schrag
Division of Bacterial and Mycotic Diseases, Respiratory Diseases Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:185-94. 2004..Successes and limitations of this emergency surveillance can guide preparations for future outbreaks of SARS or respiratory diseases of unknown etiology...
Sensitive and broadly reactive reverse transcription-PCR assays to detect novel paramyxovirusesSuxiang Tong
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 46:2652-8. 2008..The assays were specific to the respective group of genera or subfamily viruses. This set of primers enhances our ability to look for novel viruses in outbreaks and diseases of unknown etiology...
Direct sequencing of SARS-coronavirus S and N genes from clinical specimens shows limited variationSuxiang Tong
National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS G17, Atlanta, GA 30333, USA
J Infect Dis 190:1127-31. 2004..These findings are a part of the expanding investigation of the evolution of how this virus adapts to a new host...
Trends in hospitalizations for pneumonia among persons aged 65 years or older in the United States, 1988-2002Alicia M Fry
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 294:2712-9. 2005..Pneumonia causes significant mortality and morbidity among persons aged 65 years or older. However, few studies have explored trends according to age groups, which may affect intervention strategies...
Severe acute respiratory syndrome in childrenLauren J Stockman
Epidemiology Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 26:68-74. 2007..We reviewed the epidemiologic and clinical features of SARS in children and discuss implications of these findings for diagnosis, treatment and prevention of SARS...
Recombinant protein-based assays for detection of antibodies to severe acute respiratory syndrome coronavirus spike and nucleocapsid proteinsLia M Haynes
National Centers for Immunization and Respiratory Diseases, Division of Viral Diseases, Respiratory and Gastroenteritis Viruses Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G 18, Atlanta, GA 30333
Clin Vaccine Immunol 14:331-3. 2007..These assays will be useful not only for routine SARS coronavirus diagnostics but also for epidemiological and antibody kinetic studies...
Respiratory syncytial virus and Staphylococcus aureus coinfection in children hospitalized with pneumoniaLauren J Stockman
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 29:1048-50. 2010..RSV-S. aureus patients were younger and had less medical comorbidity than those without RSV...
SARS-coronavirus replication in human peripheral monocytes/macrophagesMamadi Yilla
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS C22, Atlanta, GA 30333, USA
Virus Res 107:93-101. 2005..Given the importance of monocytes/macrophages to the immune response, it is possible that their infection by SARS-CoV and alteration of this infection by IFN-alpha may be important to the course of the infection in humans...
Human bocavirus: a novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in ThailandAlicia M Fry
Epidemiology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 195:1038-45. 2007..We detected human bocavirus (HBoV) infection in 4.5% of hospitalized patients with pneumonia in rural Thailand. However, the role of HBoV as a pathogen is unclear...
Severe bronchiolitis and respiratory syncytial virus among young children in HawaiiKrista L Yorita
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
Pediatr Infect Dis J 26:1081-8. 2007..Our objective was to describe the incidence and epidemiology of severe bronchiolitis, respiratory syncytial virus (RSV), and pneumonia among children in Hawaii...
Therapeutic monoclonal antibody treatment targeting respiratory syncytial virus (RSV) G protein mediates viral clearance and reduces the pathogenesis of RSV infection in BALB/c miceLia M Haynes
National Centers for Immunization and Respiratory Diseases, Div of Viral Diseases, Respiratory and Gastroenteritis Viruses Branch, 1600 Clifton Rd NE, Mailstop G 18, Atlanta, GA 30333, USA
J Infect Dis 200:439-47. 2009....
Outbreak of severe respiratory disease associated with emergent human adenovirus serotype 14 at a US air force training facility in 2007Jacqueline E Tate
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 199:1419-26. 2009..We investigated this outbreak to better understand its epidemiology, clinical spectrum, and associated risk factors...
Persistent parvovirus B19 infection without the development of chronic anemia in HIV-infected and -uninfected children: the Women and Infants Transmission StudyAshley C LaMonte
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 189:847-51. 2004..Of the 5 children, none had evidence of B19-associated anemia. Our data suggest that B19 infections can persist in children without the development of symptomatic anemia...
SARS preparedness and response planningUmesh D Parashar
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:384-5. 2004
Use of respiratory syncytial virus surveillance data to optimize the timing of immunoprophylaxisCatherine A Panozzo
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 126:e116-23. 2010..We present an approach to using surveillance data to help guide application of AAP recommendations for immunoprophylaxis to local patterns of RSV outbreaks...
Outpatient and hospital visits associated with otitis media among American Indian and Alaska native children younger than 5 yearsAaron T Curns
Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
Pediatrics 109:E41-1. 2002..To describe the burden of otitis media (OM) among American Indian and Alaska Native (AI/AN) children...
Mortality associated with influenza and respiratory syncytial virus in the United StatesWilliam W Thompson
Influenza Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
JAMA 289:179-86. 2003..Influenza and respiratory syncytial virus (RSV) cause substantial morbidity and mortality. Statistical methods used to estimate deaths in the United States attributable to influenza have not accounted for RSV circulation...
Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infectionRalph A Tripp
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Neuroimmunol 129:141-53. 2002..These results suggest that SP receptor expression may be important in the development of primary and secondary immune responses to respiratory virus infections...
Burden of encephalitis-associated hospitalizations in the United States, 1988-1997Nino Khetsuriani
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 35:175-82. 2002..The average cost of an encephalitis-associated hospitalization, as determined by the Healthcare Cost and Utilization Project for 1997, was $28,151, for an annual national cost of hospitalization of $650 million...
Molecular epidemiology of adenovirus type 7 in the United States, 1966-2000Dean D Erdman
Divivion of Viral ans Ricksettial Diseases, Centers for Disease Control and Prevention, Mailstio G 09, 1600 Clifton Road, Atlanta, GA 30333, USA
Emerg Infect Dis 8:269-77. 2002..The appearance of Ad7d2 and Ad7h in North America represents recent introduction of these viruses from previously geographically restricted areas and may herald a shift in predominant genome type circulating in the United States...
Multiplex assay for detection of strain-specific antibodies against the two variable regions of the G protein of respiratory syncytial virusLes P Jones
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Diagn Lab Immunol 9:633-8. 2002..This assay system detected group- and, to some extent, genotype-specific responses to RSV infection and can be used to investigate the role of strain differences in RSV disease...
Peripheral blood mononuclear cells from infants hospitalized because of respiratory syncytial virus infection express T helper-1 and T helper-2 cytokines and CC chemokine messenger RNARalph A Tripp
National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 185:1388-94. 2002..The results suggest that RSV infection induces both Th1 and Th2 cytokine expression and CC chemokine expression...
Outbreak of pneumonia associated with emergent human adenovirus serotype 14--Southeast Alaska, 2008Douglas H Esposito
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 202:214-22. 2010..In September 2008, an outbreak of pneumonia associated with an emerging human adenovirus (human adenovirus serotype 14 [HAdV-14]) occurred on a rural Southeast Alaska island. Nine patients required hospitalization, and 1 patient died...
Viral respiratory infections in hospitalized and community control children in AlaskaRosalyn J Singleton
Alaska Native Tribal Health Consortium, Anchorage, Alaska
J Med Virol 82:1282-90. 2010..Rhinovirus and adenovirus were detected in two-thirds of hospitalized children, but their frequent detection in control children made their role in respiratory hospitalization uncertain...
Viral meningitis-associated hospitalizations in the United States, 1988-1999Nino Khetsuriani
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Neuroepidemiology 22:345-52. 2003..3 billion for the 5-year period. In summary, viral meningitis remains an important cause of morbidity and financial burden and merits efforts to improve diagnostic, treatment, and prevention options...
Health care transmission of a newly emergent adenovirus serotype in health care personnel at a military hospital in Texas, 2007Fernanda C Lessa
Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 200:1759-65. 2009..From April through June 2007, 15 trainees at one base were hospitalized for pneumonia due to Ad14. Subsequent reports of febrile respiratory illness among health care personnel suggested nosocomial transmission...
Enhanced disease and pulmonary eosinophilia associated with formalin-inactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance PLia M Haynes
Division of Viral and Rickettsial Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Virol 77:9831-44. 2003..These data suggest that the G glycoprotein, and in particular the G glycoprotein CX3C motif, is key in the enhanced inflammatory response to FI-RSV vaccination, possibly through the induction of substance P...
Identification of adenoviruses in fecal specimens from wild chimpanzees (Pan trogylodytes schweinfurthii) in western TanzaniaSuxiang Tong
Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Trop Med Hyg 82:967-70. 2010..The species C adenovirus sequences suggest possible recombination with a human adenovirus. The source of these viruses and disease association is not known...
The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance PRalph A Tripp
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 77:6580-4. 2003..These data suggest new approaches for treating some aspects of RSV disease...
Characterization of a novel coronavirus associated with severe acute respiratory syndromePaul A Rota
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Science 300:1394-9. 2003..Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses...
Case-control study of risk factors for human infection with a new zoonotic paramyxovirus, Nipah virus, during a 1998-1999 outbreak of severe encephalitis in MalaysiaU D Parashar
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 181:1755-9. 2000..The outbreak stopped after pigs in the affected areas were slaughtered and buried. Direct, close contact with pigs was the primary source of human Nipah infection, but other sources, such as infected dogs and cats, cannot be excluded...
CX3C chemokine mimicry by respiratory syncytial virus G glycoproteinR A Tripp
National Centers for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Mailstop G 09, 1600 Clifton Rd, Atlanta, GA, USA
Nat Immunol 2:732-8. 2001..We also show that CX3CR1 facilitates RSV infection of cells. Thus, G glycoprotein interaction with CX3CR1 probably plays a key role in the biology of RSV infection...
Human parvovirus B19 and pregnancyL J Anderson
Division of Viral Diseases, Centers for Disease Control, Atlanta, Georgia
Clin Perinatol 15:273-86. 1988..The most common clinical manifestations of B19 infection are erythema infectiosum and aplastic crisis in patients with chronic hemolytic anemias...
Investigation of porcine parvovirus among persons with hemophilia receiving Hyate:C porcine factor VIII concentrateJ M Soucie
Division of AIDS, STD, and TB Laboratory Research, and the Respiratory and Enterovirus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30033, USA
Transfusion 40:708-11. 2000..This report describes an investigation to determine the extent of product contamination and to evaluate past recipients of porcine clotting factor (Hyate:C, Speywood Biopharm) for evidence of PPV infection...
Simultaneous detection and identification of human parainfluenza viruses 1, 2, and 3 from clinical samples by multiplex PCRJ E Echevarria
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 36:1388-91. 1998..Our multiplex RT-PCR assays provide sensitive, specific, and simplified tools for the rapid diagnosis of HPIV infections...
Human parainfluenza virus-associated hospitalizations among children less than five years of age in the United StatesM E Counihan
Rollins School of Public Health, Emory University, Atlanta, GA, USA
Pediatr Infect Dis J 20:646-53. 2001..More precise estimates of HPIV-associated hospitalizations would require large prospective studies of HPIV-associated diseases by more sensitive viral testing methods, such as polymerase chain reaction techniques...
Novel human rhinoviruses and exacerbation of asthma in childrenNino Khetsuriani
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 14:1793-6. 2008..Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C...
Variation in timing of respiratory syncytial virus outbreaks: lessons from national surveillanceCatherine A Panozzo
Division of Viral Diseases, NCIRD, CoCID, CDC, Atlanta, GA 30333, USA
Pediatr Infect Dis J 26:S41-5. 2007..Surveillance data can, however, be used to determine how well national patterns represent local patterns. Further analyses are needed to determine how local surveillance data can be used to guide timing of immune prophylaxis...
Prevalence of viral respiratory tract infections in children with asthmaNino Khetsuriani
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Allergy Clin Immunol 119:314-21. 2007..Previous studies support a strong association between viral respiratory tract infections and asthma exacerbations. The effect of newly discovered viruses on asthma control is less well defined...
Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997D K Shay
Respiratory and Enteric Viruses Branch and National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 183:16-22. 2001....
An epidemic of acute hemorrhagic conjunctivitis in American Samoa caused by coxsackievirus A24 variantL A Sawyer
Division of Viral Diseases, Centers for Disease Control, Atlanta, GA 30333
Am J Epidemiol 130:1187-98. 1989..The presence of these antibodies correlated with protection against coxsackievirus A24 variant infection in this outbreak...
Human metapneumovirus infection among children hospitalized with acute respiratory illnessJames A Mullins
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 10:700-5. 2004..Further investigations to better characterize HMPV infection and its clinical effect are needed...
Induction of cytokine mRNA in peripheral blood mononuclear cells of infants after the first dose of measles vaccineH Li
Respiratory and Enteric Viruses Branch, Measles Section MS D11, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
Vaccine 19:4896-900. 2001..09, one tailed Fisher's test). The observed measles specific induction of IL-5 mRNA is suggestive of a possible association between IL-5 production and an antibody response to measles virus...
Treatment of respiratory syncytial virus infection with vitamin A: a randomized, placebo-controlled trial in Santiago, ChileS F Dowell
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
Pediatr Infect Dis J 15:782-6. 1996..In respiratory syncytial virus (RSV) infection, as with measles, low serum vitamin A concentrations correlate with increased severity of illness...
Purity, antigenicity and immunogenicity of the hepatitis B surface antigen purified by five different methodsH A Fields
Division of Viral Diseases, Centers for Disease Control, Atlanta, Georgia
J Virol Methods 22:283-94. 1988..The contaminating proteins were identified as alpha-2-macroglobulin, heavy chains of IgG and IgM, immunoglobulin kappa chain, and albumin...
Real-time detection of virus particles and viral protein expression with two-color nanoparticle probesAmit Agrawal
Department of Biomedical Engineering and Chemistry, Emory University and Georgia Institute of Technology, Atlanta, Georgia 30322, USA
J Virol 79:8625-8. 2005..A major development is use of dual-color quantum dots or fluorescence energy transfer nanobeads that can be simultaneously excited with a single light source...
Risk factors for bronchiolitis-associated deaths among infants in the United StatesRobert C Holman
Respiratory and Enteric Viruses Branch, Division of Viral and Ricksettial Diseases, National Center for Infectious Diseases, Center for Disease Control and Prevention/DHHS, Atlanta, GA 30333, USA
Pediatr Infect Dis J 22:483-90. 2003..Although infants weighing <2500 g at birth are at increased risk for dying with bronchiolitis, the majority of bronchiolitis deaths occur among infants of normal birth weight...
Application of proteomics methods for pathogen discoveryYiming Ye
Biotechnology Core Facility Branch, Division of Scientific Resources, NCPDCID, Atlanta, GA, USA
J Virol Methods 163:87-95. 2010....
Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strainsNathalie Bastien
National Microbiology Laboratory, Canadian Science Center for Human and Animal Health, 1015 Arlington Street, Winnipeg, Manitoba, Canada R3E 3R2
Virus Res 93:51-62. 2003..1-97.6% identity between the two distinct clusters The P gene showed more diversity with 81.6-85.7% amino acid identity for isolates between the two clusters, and 94.6-100% for isolates within the same cluster...
Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groupsGuy Boivin
Research Center in Infectious Diseases, Regional Virology Laboratory, Laval University, Quebec City, Canada
J Infect Dis 186:1330-4. 2002..These findings suggest that HMPV can be associated with severe lower-respiratory-tract infections in very young children, the elderly, and immunocompromised patients...
Human metapneumovirus infections in young and elderly adultsAnn R Falsey
Infectious Diseases Unit, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, 1425 Portland Avenue, Rochester, NY 14621, USA
J Infect Dis 187:785-90. 2003..In conclusion, hMPV infection occurs in adults of all ages and may account for a significant portion of persons hospitalized with respiratory infections during some years...
Guidelines for preventing health-care--associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory CommitteeOfelia C Tablan
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, USA
MMWR Recomm Rep 53:1-36. 2004....
Rhinovirus-associated hospitalizations in young childrenE Kathryn Miller
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA
J Infect Dis 195:773-81. 2007..Rhinoviruses frequently cause the common cold but have not been considered important causes of acute respiratory hospitalizations in children...
Human bocavirus: a new viral pathogenLarry J Anderson
Clin Infect Dis 44:911-2. 2007
Annual variation in respiratory syncytial virus season and decisions regarding immunoprophylaxis with palivizumabH Cody Meissner
Pediatric Infectious Disease Division, Tufts-New England Medical Center, Tufts University School of Medicine, 750 Washington St, Boston, MA 02111, USA
Pediatrics 114:1082-4. 2004
Prior airway exposure to allergen increases virus-induced airway hyperresponsivenessMika J Mäkelä
Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colo 80206, USA
J Allergy Clin Immunol 112:861-9. 2003....
Coronavirus antibodies in bat biologistsLauren J Stockman
Emerg Infect Dis 14:999-1000. 2008
Severe acute respiratory syndrome: review and lessons of the 2003 outbreakUmesh D Parashar
Int J Epidemiol 33:628-34. 2004
Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, ChinaGuodong Liang
Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China
Emerg Infect Dis 10:1774-81. 2004..This study shows the effectiveness of a collaborative, multilaboratory response to diagnose SARS...
