John F Anderson

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Prevalence and genetic characterization of Powassan virus strains infecting Ixodes scapularis in Connecticut
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504 1106, USA
    Am J Trop Med Hyg 87:754-9. 2012
  2. ncbi request reprint Susceptibility of Cimex lectularius (Hemiptera: Cimicidae) to pyrethroid insecticides and to insecticidal dusts with or without pyrethroid insecticides
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504 1106, USA
    J Econ Entomol 105:1789-95. 2012
  3. pmc Horizontal and vertical transmission of West Nile virus genotype NY99 by Culex salinarius and genotypes NY99 and WN02 by Culex tarsalis
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, Connecticut, USA
    Am J Trop Med Hyg 86:134-9. 2012
  4. ncbi request reprint The Lyme disease agent exploits a tick protein to infect the mammalian host
    Nandhini Ramamoorthi
    Sections of Rheumatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nature 436:573-7. 2005
  5. pmc A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector
    Sukanya Narasimhan
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell Host Microbe 2:7-18. 2007
  6. ncbi request reprint Isolations of Potosi virus from mosquitoes (Diptera: Culicidae) collected in Connecticut
    Philip M Armstrong
    The Connecticut Agricultural Experiment Station, 123 Huntington St, New Haven, CT 06504, USA
    J Med Entomol 42:875-81. 2005
  7. pmc A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cells
    Nathalie Bonafe
    L2 Diagnostics, LLC, 300 George Street, New Haven, CT 06511, USA
    Vaccine 27:213-22. 2009
  8. pmc Antiviral peptides targeting the west nile virus envelope protein
    Fengwei Bai
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Virol 81:2047-55. 2007
  9. ncbi request reprint A recombinant envelope protein vaccine against West Nile virus
    Michel Ledizet
    L2 Diagnostics, LLC, 300 George Street, New Haven, CT 06511, USA
    Vaccine 23:3915-24. 2005
  10. pmc Role of outer surface protein D in the Borrelia burgdorferi life cycle
    Xin Li
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520 8031, USA
    Infect Immun 75:4237-44. 2007

Detail Information

Publications44

  1. pmc Prevalence and genetic characterization of Powassan virus strains infecting Ixodes scapularis in Connecticut
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504 1106, USA
    Am J Trop Med Hyg 87:754-9. 2012
    ..These findings suggest that POWV was independently introduced into these geographical locations in Connecticut and maintained focally in their respective environments. An improved method of isolation of POWV in vitro is described...
  2. ncbi request reprint Susceptibility of Cimex lectularius (Hemiptera: Cimicidae) to pyrethroid insecticides and to insecticidal dusts with or without pyrethroid insecticides
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504 1106, USA
    J Econ Entomol 105:1789-95. 2012
    ..Desiccant dusts, with their physical mode of action and long residual activity, appear to be superior to sprayable pyrethroid products for killing bed bugs...
  3. pmc Horizontal and vertical transmission of West Nile virus genotype NY99 by Culex salinarius and genotypes NY99 and WN02 by Culex tarsalis
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, Connecticut, USA
    Am J Trop Med Hyg 86:134-9. 2012
    ..Our findings do not support the previously published hypothesis that genotype NY99 was replaced in the New World by WN02 because of a shorter extrinsic incubation of WN02...
  4. ncbi request reprint The Lyme disease agent exploits a tick protein to infect the mammalian host
    Nandhini Ramamoorthi
    Sections of Rheumatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nature 436:573-7. 2005
    ..scapularis drastically reduced the capacity of tick-borne spirochaetes to infect mice. These results show the capacity of a pathogen to use a secreted arthropod protein to help it colonize the mammalian host...
  5. pmc A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector
    Sukanya Narasimhan
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell Host Microbe 2:7-18. 2007
    ..burgdorferi at the tick feeding site in mice. These data demonstrate that pathogens can exploit arthropod molecules to defuse mammalian responses in order to successfully enter the vector...
  6. ncbi request reprint Isolations of Potosi virus from mosquitoes (Diptera: Culicidae) collected in Connecticut
    Philip M Armstrong
    The Connecticut Agricultural Experiment Station, 123 Huntington St, New Haven, CT 06504, USA
    J Med Entomol 42:875-81. 2005
    ..This finding represents the first detection of POTV in the northeastern United States where it infects a diverse array of mosquito species...
  7. pmc A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cells
    Nathalie Bonafe
    L2 Diagnostics, LLC, 300 George Street, New Haven, CT 06511, USA
    Vaccine 27:213-22. 2009
    ..These observations demonstrate that baculovirus-produced rWNV-E can be formulated with aluminum hydroxide to produce a stable and safe vaccine which induces humoral immunity that can protect against WNV infection...
  8. pmc Antiviral peptides targeting the west nile virus envelope protein
    Fengwei Bai
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Virol 81:2047-55. 2007
    ..These short peptides serve as the basis for developing new therapeutics for West Nile encephalitis and, potentially, other flaviviruses...
  9. ncbi request reprint A recombinant envelope protein vaccine against West Nile virus
    Michel Ledizet
    L2 Diagnostics, LLC, 300 George Street, New Haven, CT 06511, USA
    Vaccine 23:3915-24. 2005
    ..This recombinant form of E protein, combined with aluminum hydroxide, is a candidate vaccine that may protect humans and horses against WN virus infections...
  10. pmc Role of outer surface protein D in the Borrelia burgdorferi life cycle
    Xin Li
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520 8031, USA
    Infect Immun 75:4237-44. 2007
    ..These data suggest that B. burgdorferi can compensate for the lack of OspD in both ticks and mice and that OspD may have a nonessential, secondary, role in B. burgdorferi persistence within I. scapularis...
  11. pmc An Ixodes scapularis protein required for survival of Anaplasma phagocytophilum in tick salivary glands
    Bindu Sukumaran
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Exp Med 203:1507-17. 2006
    ..These data demonstrate the specific requirement of a pathogen for a tick salivary protein to persist within the arthropod and provide a paradigm for understanding how Rickettsia-like pathogens are maintained within vectors...
  12. pmc Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing
    Terrence Town
    Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 30:242-53. 2009
    ..Collectively, these results demonstrate that TLR7 and IL-23-dependent WNV responses represent a vital host defense mechanism that operates by affecting immune cell homing to infected target cells...
  13. ncbi request reprint Control of mosquitoes in catch basins in Connecticut with Bacillus thuringiensis israelensis, Bacillus sphaericus, [corrected] and spinosad
    John F Anderson
    The Connecticut Agricultural Experiment Station, PO Box 1106, New Haven, CT 06504, USA
    J Am Mosq Control Assoc 27:45-55. 2011
    ..The application of 1 Natular XRT tablet, each weighing approximately 40.5 g (6.25% spinosad), to individual catch basins in 2009 significantly reduced the total numbers of larvae for 5 wk...
  14. pmc OspB antibody prevents Borrelia burgdorferi colonization of Ixodes scapularis
    Erol Fikrig
    Section of Rheumatology, Department of Internal Medicine Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Infect Immun 72:1755-9. 2004
    ..burgdorferi colonization of I. scapularis, highlighting a specific role for OspB in spirochete- arthropod interactions and suggesting new antibody-mediated strategies for interfering with B. burgdorferi transmission...
  15. pmc Serum antibodies to West Nile virus in naturally exposed and vaccinated horses
    Louis A Magnarelli
    Connecticut Agricultural Experiment Station, New Haven, CT 06504, USA
    J Med Microbiol 57:1087-93. 2008
    ..Both serological tests were useful in confirming past infections with WNV, but there was no evidence that horses with undiagnosed illnesses were exposed to WNV prior to a 1999 outbreak in Connecticut, USA...
  16. ncbi request reprint Importance of vertical and horizontal transmission of West Nile virus by Culex pipiens in the Northeastern United States
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT 06511, USA
    J Infect Dis 194:1577-9. 2006
    ..This suggests that WNV survives winter in unfed, vertically infected C. pipiens with amplification initiated in spring by horizontal transmission...
  17. ncbi request reprint Epidemiology of West Nile virus in Connecticut: a five-year analysis of mosquito data 1999-2003
    Theodore G Andreadis
    Connecticut Agricultural Experiment Station, New Haven, Connecticut 06504, USA
    Vector Borne Zoonotic Dis 4:360-78. 2004
    ....
  18. ncbi request reprint TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi
    Utpal Pal
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell 119:457-68. 2004
    ..Identification of an I. scapularis receptor for B. burgdorferi is the first step toward elucidating arthropod ligands that are required for survival of spirochetes in nature...
  19. ncbi request reprint The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks
    Xin Li
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8031, USA
    Mol Microbiol 63:694-710. 2007
    ..Dps is critical for spirochaete persistence within ticks, and strategies to interfere with Dps could potentially reduce Borrelia populations in nature and thereby influence the incidence of Lyme disease...
  20. pmc A C-type lectin collaborates with a CD45 phosphatase homolog to facilitate West Nile virus infection of mosquitoes
    Gong Cheng
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell 142:714-25. 2010
    ..During the mosquito blood-feeding process, WNV infection was blocked in vivo with mosGCTL-1 antibodies. A molecular understanding of flaviviral-arthropod interactions may lead to strategies to control viral dissemination in nature...
  21. pmc Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission
    Sukanya Narasimhan
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 2:e451. 2007
    ..Defining this subset of proteins will promote a mechanistic understanding of novel I. scapularis proteins critical for the initiation of tick feeding and for Borrelia transmission...
  22. pmc Host feeding patterns of Culex mosquitoes and West Nile virus transmission, northeastern United States
    Goudarz Molaei
    The Connecticut Agricultural Experiment Station, New Haven, Connecticut 06504, USA
    Emerg Infect Dis 12:468-74. 2006
    ..salinarius and 1 Cx. pipiens. Results suggest that Cx. salinarius is an important bridge vector to humans, while Cx. pipiens and Cx. restuans are more efficient enzootic vectors in the northeastern United States...
  23. pmc An in vivo transfection approach elucidates a role for Aedes aegypti thioester-containing proteins in flaviviral infection
    Gong Cheng
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e22786. 2011
    ..In vivo transfection of AeTEP-1 into Ae. aegypti significantly reduced dengue virus infection, suggesting that the approach can further our understanding of pathogen-mosquito interactions...
  24. ncbi request reprint West Nile virus from female and male mosquitoes (Diptera: Culicidae) in subterranean, ground, and canopy habitats in Connecticut
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT 06504 1106, USA
    J Med Entomol 43:1010-9. 2006
    ..The placement of traps in tree canopies and in catch basins can be used to augment current practices of placement of traps near the ground for surveillance of mosquitoes infected with WNV and for studies of the ecology of WNV...
  25. ncbi request reprint Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
    Tian Wang
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut 06520, USA
    Nat Med 10:1366-73. 2004
    ..Collectively, WNV infection leads to a Tlr3-dependent inflammatory response, which is involved in brain penetration of the virus and neuronal injury...
  26. pmc Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-β1/Smad6 signaling
    Hameeda Sultana
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 189:3150-8. 2012
    ....
  27. pmc Protective and therapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus
    L Hannah Gould
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    J Virol 79:14606-13. 2005
    ..These recombinant human scFvs are potential candidates for immunoprophylaxis and therapy of flavivirus infections...
  28. doi request reprint Isolations of Jamestown Canyon virus (Bunyaviridae: Orthobunyavirus) from field-collected mosquitoes (Diptera: Culicidae) in Connecticut, USA: a ten-year analysis, 1997-2006
    Theodore G Andreadis
    The Connecticut Agricultural Experiment Station, New Haven, CT 06504, USA
    Vector Borne Zoonotic Dis 8:175-88. 2008
    ....
  29. ncbi request reprint Extrinsic incubation periods for horizontal and vertical transmission of West Nile virus by Culex pipiens pipiens (Diptera: Culicidae)
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT 06405, USA
    J Med Entomol 45:445-51. 2008
    ..p. pipiens contribute to the relatively high minimum infection rates that are reached in late summer and to the survival of virus during winter and initiation of amplification in the spring in the northeastern United States...
  30. pmc OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands
    Utpal Pal
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Invest 113:220-30. 2004
    ..These studies conclusively demonstrate the importance of OspC in the invasion of tick salivary glands by B. burgdorferi, a critical step in the transmission of spirochetes from the arthropod vector to the mammalian host...
  31. pmc Disruption of Ixodes scapularis anticoagulation by using RNA interference
    Sukanya Narasimhan
    Sections of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 101:1141-6. 2004
    ..These studies demonstrate that RNA interference can silence I. scapularis genes and disrupt their physiologic function in vivo, and they identify vaccine candidates that can alter vector engorgement...
  32. ncbi request reprint Prevalence of West Nile virus in tree canopy-inhabiting Culex pipiens and associated mosquitoes
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, 123 Huntington Street, New Haven, CT 06511, USA
    Am J Trop Med Hyg 71:112-9. 2004
    ..The significantly larger numbers of WNV isolates from Cx. pipiens captured in the canopy are attributed to the significantly larger numbers of Cx. pipiens captured in the canopy in comparison to those captured in traps near the ground...
  33. ncbi request reprint Nocturnal activity of mosquitoes (Diptera: Culicidae) in a West Nile virus focus in Connecticut
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT 06405, USA
    J Med Entomol 44:1102-8. 2007
    ..In total, 39 isolations of WNV were made from seven species collected primarily during periods of total darkness. Humans are at risk of being bitten by infected mosquitoes throughout the night...
  34. pmc Molecular evolution of West Nile virus in a northern temperate region: Connecticut, USA 1999-2008
    Philip M Armstrong
    Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504, USA
    Virology 417:203-10. 2011
    ..Despite ongoing evolution of WNV, most amino acid variants occurred at low frequencies and were transient in the virus population...
  35. pmc Mosquito saliva serine protease enhances dissemination of dengue virus into the mammalian host
    Michael J Conway
    Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut, USA
    J Virol 88:164-75. 2014
    ..Molecules in mosquito saliva that facilitate viral infectivity in the vertebrate host provide novel targets that may aid in the prevention of disease. ..
  36. ncbi request reprint Tracking eastern equine encephalitis virus perpetuation in the northeastern United States by phylogenetic analysis
    Philip M Armstrong
    The Connecticut Agricultural Experiment Station, New Haven, Connecticut 06504, USA
    Am J Trop Med Hyg 79:291-6. 2008
    ..These results provide additional evidence for independent episodes of EEEV overwintering in northern foci...
  37. pmc Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold
    Girish Neelakanta
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8022, USA
    J Clin Invest 120:3179-90. 2010
    ....
  38. ncbi request reprint Aedes japonicus japonicus and associated woodland species attracted to Centers for Disease Control and Prevention miniature light traps baited with carbon dioxide and the Traptech mosquito lure
    John F Anderson
    Department of Entomology and Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06511 1106, USA
    J Am Mosq Control Assoc 28:184-91. 2012
    ..j. japonicus. These data demonstrate that the TrapTech Mosquito Lure used in combination with CO2 in a CDC miniature light trap has potential to be a versatile and simple surveillance method for Ae. j. japonicus and other species...
  39. ncbi request reprint IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection
    Tian Wang
    Department of Internal Medicine, Section of Rheumatology, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA
    J Immunol 171:2524-31. 2003
    ..These data demonstrate a distinct role for gammadelta T cells in the control of and prevention of mortality from murine WN virus infection...
  40. ncbi request reprint A recombinant envelope protein-based enzyme-linked immunosorbent assay for West Nile virus serodiagnosis
    Tian Wang
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8031, USA
    Vector Borne Zoonotic Dis 2:105-9. 2002
    ..Antibodies to the recombinant West Nile virus membrane and nonstructural 1 proteins were not detected in any of these sera. An E protein-based ELISA may aid in the serological diagnosis of West Nile virus infection...
  41. pmc West nile virus attenuates activation of primary human macrophages
    Kok Fai Kong
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8031, USA
    Viral Immunol 21:78-82. 2008
    ..Infection with WNV interferes with the downstream JAK/STAT pathway, which is important for macrophage activation. In comparison to other related flaviviruses, the differential response of proinflammatory cytokines is distinct to WNV...
  42. doi request reprint Biology of ticks
    John F Anderson
    The Connecticut Agricultural Experiment Station, New Haven, CT 06504, USA
    Infect Dis Clin North Am 22:195-215, v. 2008
    ..Key factors, including the reversion of agricultural lands to forests and a close association between people and ticks, have greatly increased the risk of tick bite and human disease...
  43. ncbi request reprint Transstadial transfer of West Nile virus by three species of ixodid ticks (Acari: Ixodidae)
    John F Anderson
    Department of Entomology, The Connecticut Agricultural Experiment Station, 123 Huntington Street, New Haven, CT 06511, USA
    J Med Entomol 40:528-33. 2003
    ..Three species of ixodid ticks acquired WN virus from viremic hosts and transstadially passed the virus, but vector competency was not demonstrated...
  44. pmc Examination of the Borrelia burgdorferi transcriptome in Ixodes scapularis during feeding
    Sukanya Narasimhan
    Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine, L Diagnostics, New Haven, Connecticut 06520, USA
    J Bacteriol 184:3122-5. 2002
    ..These data demonstrate a new approach to the global analysis of B. burgdorferi genes that are preferentially expressed within the vector during feeding...