Research Topics
| Gregory D FergusonSummaryAffiliation: Celgene Corporation Country: USA Publications
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Detail Information
Publications
Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2Gregory D Ferguson
Celgene Corporation, 4550 Towne Center Court, San Diego, CA 92121, USA
J Clin Immunol 27:210-20. 2007..Taken together, the data in this manuscript suggest CC-4047 will provide important anti-inflammatory benefit to patients and will improve the safety of NSAIDs in the treatment of SCD or other inflammatory conditions...
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cellsLaure A Moutouh-de Parseval
Celgene Corporation, San Diego, California, USA
J Clin Invest 118:248-58. 2008..These findings support the evaluation of pomalidomide as an innovative new therapy for beta-hemoglobinopathies...
Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cellsDominique Verhelle
Celgene, San Diego, California 92121, USA
Cancer Res 67:746-55. 2007....
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPasesYibing Xu
Celgene, San Diego, CA 92121, USA
Blood 114:338-45. 2009..These novel activities provide what we believe a critical mechanism by which IMiDs drugs function as therapeutic immunomodulatory agents...
Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125Alison S Williams
Airway Disease Section, National Heart and Lung Institute, Imperial College, Dovehouse St, London SW3 6LY, UK
J Pharmacol Exp Ther 322:351-9. 2007..Inhibition of JNK with small molecule kinase inhibitors may be a means of reducing ozone-induced inflammation and AHR...
