H O Smith

Summary

Affiliation: Celera Genomics
Country: USA

Publications

  1. ncbi request reprint DNA uptake signal sequences in naturally transformable bacteria
    H O Smith
    The Institute for Genomic Research, Rockville, MD 20850, USA
    Res Microbiol 150:603-16. 1999
  2. ncbi request reprint The complete genome sequence of the gastric pathogen Helicobacter pylori
    J F Tomb
    Institute for Genomic Research, Rockville, Maryland 20850, USA
    Nature 388:539-47. 1997
  3. ncbi request reprint Complete genome sequence of Treponema pallidum, the syphilis spirochete
    C M Fraser
    Institute for Genomic Research, Rockville, MD 20850, USA
    Science 281:375-88. 1998
  4. ncbi request reprint Prediction of transcription terminators in bacterial genomes
    M D Ermolaeva
    The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA
    J Mol Biol 301:27-33. 2000
  5. ncbi request reprint The sequence of the human genome
    J C Venter
    Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
    Science 291:1304-51. 2001
  6. ncbi request reprint The malaria genome sequencing project: complete sequence of Plasmodium falciparum chromosome 2
    M J Gardner
    Institute of Genomic Research, Naval Medical Research Center, Rockville, MD, USA
    Parassitologia 41:69-75. 1999
  7. ncbi request reprint Complete genome sequence of a virulent isolate of Streptococcus pneumoniae
    H Tettelin
    The Institute for Genomic Research (TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 293:498-506. 2001
  8. doi request reprint Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Escherichia coli
    P D Weyman
    Department of Synthetic Biology and Bioenergy, The J Craig Venter Institute, Rockville, MD 20850, USA
    Microbiology 157:1363-74. 2011

Collaborators

Detail Information

Publications8

  1. ncbi request reprint DNA uptake signal sequences in naturally transformable bacteria
    H O Smith
    The Institute for Genomic Research, Rockville, MD 20850, USA
    Res Microbiol 150:603-16. 1999
    ..Neisseria meningitidis contains 1891 copies of the USS sequence 5'-GCCGTCTGAA. The USSs are often found in the base paired stem of transcription terminators...
  2. ncbi request reprint The complete genome sequence of the gastric pathogen Helicobacter pylori
    J F Tomb
    Institute for Genomic Research, Rockville, Maryland 20850, USA
    Nature 388:539-47. 1997
    ..pylori has a few regulatory networks, and a limited metabolic repertoire and biosynthetic capacity. Its survival in acid conditions depends, in part, on its ability to establish a positive inside-membrane potential in low pH...
  3. ncbi request reprint Complete genome sequence of Treponema pallidum, the syphilis spirochete
    C M Fraser
    Institute for Genomic Research, Rockville, MD 20850, USA
    Science 281:375-88. 1998
    ..pallidum genome sequence with that of another pathogenic spirochete, Borrelia burgdorferi, the agent of Lyme disease, identified unique and common genes and substantiates the considerable diversity observed among pathogenic spirochetes...
  4. ncbi request reprint Prediction of transcription terminators in bacterial genomes
    M D Ermolaeva
    The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA
    J Mol Biol 301:27-33. 2000
    ..A set of 131 experimentally determined E. coli terminators was used to evaluate the sensitivity of the method, which ranges from 89 % to 98 %, with corresponding false positive rates of 2 % and 18 %...
  5. ncbi request reprint The sequence of the human genome
    J C Venter
    Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
    Science 291:1304-51. 2001
    ..Less than 1% of all SNPs resulted in variation in proteins, but the task of determining which SNPs have functional consequences remains an open challenge...
  6. ncbi request reprint The malaria genome sequencing project: complete sequence of Plasmodium falciparum chromosome 2
    M J Gardner
    Institute of Genomic Research, Naval Medical Research Center, Rockville, MD, USA
    Parassitologia 41:69-75. 1999
    ..Within 2-3 years, the sequence of almost all P. falciparum genes will have been determined, paving the way for genetic, biochemical, and immunological research aimed at developing new drugs and vaccines against malaria...
  7. ncbi request reprint Complete genome sequence of a virulent isolate of Streptococcus pneumoniae
    H Tettelin
    The Institute for Genomic Research (TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 293:498-506. 2001
    ..Comparative genome hybridization with DNA arrays revealed strain differences in S. pneumoniae that could contribute to differences in virulence and antigenicity...
  8. doi request reprint Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Escherichia coli
    P D Weyman
    Department of Synthetic Biology and Bioenergy, The J Craig Venter Institute, Rockville, MD 20850, USA
    Microbiology 157:1363-74. 2011
    ..roseopersicina hydrogenase. This result demonstrates that the accessory genes from AltDE can complement their counterparts from T. roseopersicina and that the two hydrogenases share similar maturation mechanisms...