Amos Baruch

Summary

Affiliation: Celera Genomics
Country: USA

Publications

  1. ncbi request reprint Enzyme activity--it's all about image
    Amos Baruch
    Department of Chemical Proteomics, Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA
    Trends Cell Biol 14:29-35. 2004
  2. ncbi request reprint Development of activity-based probes for trypsin-family serine proteases
    Zhengying Pan
    Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA
    Bioorg Med Chem Lett 16:2882-5. 2006
  3. pmc Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins
    Daniel H Wreschner
    Department of Cell Research and Immunology, George S Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel
    Protein Sci 11:698-706. 2002
  4. ncbi request reprint Chemical approaches for functionally probing the proteome
    Doron Greenbaum
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, USA
    Mol Cell Proteomics 1:60-8. 2002
  5. ncbi request reprint A novel protein derived from the MUC1 gene by alternative splicing and frameshifting
    Fiana Levitin
    Department of Cell Research and Immunology, Tel Aviv University, Ramat Aviv 69978, Israel
    J Biol Chem 280:10655-63. 2005
  6. pmc A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis
    Kristina K Hansen
    Proteinases and Inflammation Network, Mucosal Inflammation Research Group, Department of Pharmacology, University of Calgary, Calgary, AB, Canada T2N 4N1
    Proc Natl Acad Sci U S A 102:8363-8. 2005
  7. doi request reprint Applications for chemical probes of proteolytic activity
    Matthew Bogyo
    Stanford University, Stanford, California, USA
    Curr Protoc Protein Sci . 2004

Collaborators

  • Douglas A Jeffery
  • Zhengying Pan
  • M D Hollenberg
  • Matthew Bogyo
  • Daniel H Wreschner
  • Doron Greenbaum
  • Fiana Levitin
  • Kristina K Hansen
  • Ravit Ziv
  • Nechama Smorodinsky
  • Iafa Keydar
  • Joseph Zaretsky
  • Patricia Andrade-Gordon
  • David Greaves
  • Merav Yoeli-Lerner
  • Benny Gil
  • Beatrice Lifschitz
  • Andrea Gat
  • Nathalie Vergnolle
  • Keren Stiegman
  • John L Wallace
  • Alina Cholostoy
  • Sima Shina
  • Mordechai Weiss
  • Laurie Cellars
  • Mor Li Hartmann
  • Sheila Zrihan-Licht
  • Philip M Sherman
  • Moshe Simha
  • Yona Stadler
  • Anna Borodovsky
  • Huib Ovaa
  • Benedikt Kessler
  • Michael A McGuckin
  • Stefanie J Williams
  • Linda Hayrapetian
  • Merav Yoeli
  • Alma Burlingame
  • Siamon Gordon
  • His Hsien Lin
  • Zsuzsanna Darula
  • Katlin F Medzihradszky
  • Martin Stacey
  • Liron Okun
  • Pavlos Neophytou

Detail Information

Publications7

  1. ncbi request reprint Enzyme activity--it's all about image
    Amos Baruch
    Department of Chemical Proteomics, Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA
    Trends Cell Biol 14:29-35. 2004
    ..Such technologies have the potential to be integrated into drug-development programs to facilitate both the functional validation of pharmaceutical targets and the treatment of human disease...
  2. ncbi request reprint Development of activity-based probes for trypsin-family serine proteases
    Zhengying Pan
    Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA
    Bioorg Med Chem Lett 16:2882-5. 2006
    ..We present here the application of multiple probes in enzyme activity profiling of intact mast cells, a type of inflammatory cell implicated in allergy and autoimmune diseases...
  3. pmc Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins
    Daniel H Wreschner
    Department of Cell Research and Immunology, George S Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel
    Protein Sci 11:698-706. 2002
    ..It could well lead to the rational design and identification of molecules that, by binding to one of the cleaved partners, will act either as agonists or antagonists, alter signal transduction and, hence, cellular behavior...
  4. ncbi request reprint Chemical approaches for functionally probing the proteome
    Doron Greenbaum
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, USA
    Mol Cell Proteomics 1:60-8. 2002
    ..Ultimately, this technology allows the rapid identification of potential drug targets and small molecule lead compounds targeted to them...
  5. ncbi request reprint A novel protein derived from the MUC1 gene by alternative splicing and frameshifting
    Fiana Levitin
    Department of Cell Research and Immunology, Tel Aviv University, Ramat Aviv 69978, Israel
    J Biol Chem 280:10655-63. 2005
    ....
  6. pmc A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis
    Kristina K Hansen
    Proteinases and Inflammation Network, Mucosal Inflammation Research Group, Department of Pharmacology, University of Calgary, Calgary, AB, Canada T2N 4N1
    Proc Natl Acad Sci U S A 102:8363-8. 2005
    ..rodentium-induced inflammation. These data point to an important role for both pathogen-induced host serine proteinases and PAR2 in the setting of infectious colitis...
  7. doi request reprint Applications for chemical probes of proteolytic activity
    Matthew Bogyo
    Stanford University, Stanford, California, USA
    Curr Protoc Protein Sci . 2004
    ....