Christine S Walsh

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. pmc Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas
    Christine S Walsh
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, David Geffen School of Medicine at UCLA, Los Angeles, California 90048, USA
    Clin Cancer Res 14:7645-51. 2008
  2. doi request reprint Molecular signatures of ovarian cancer: from detection to prognosis
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Mol Diagn Ther 14:13-22. 2010
  3. ncbi request reprint Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Women s Cancer Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Boulevard, Suite 290W, Los Angeles, CA 90048, USA
    Gynecol Oncol 104:660-4. 2007
  4. ncbi request reprint Contemporary progress in ovarian cancer screening
    Christine S Walsh
    Department of Obstetrics and Gynecology, University of California, Los Angeles, David Geffen School of Medicine at UCLA, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Suite 160W, Los Angeles, CA 90048, USA
    Curr Oncol Rep 9:485-93. 2007
  5. pmc Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening
    Christine S Walsh
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gynecol Oncol 116:516-21. 2010
  6. doi request reprint ERCC5 is a novel biomarker of ovarian cancer prognosis
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Women s Cancer Research Institute, Samuel Oschin Comprehensive Cancer Institute, David Geffen School of Medicine, University of California at Los Angeles, CA 90048, USA
    J Clin Oncol 26:2952-8. 2008
  7. ncbi request reprint Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene
    Claudia I Muller
    Division of Hematology Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Leuk Res 31:27-32. 2007
  8. doi request reprint Xeroderma pigmentosum complementation group C single-nucleotide polymorphisms in the nucleotide excision repair pathway correlate with prolonged progression-free survival in advanced ovarian cancer
    Nicole D Fleming
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, Los Angeles, California 90048, USA
    Cancer 118:689-97. 2012
  9. doi request reprint CA125 surveillance increases optimal resectability at secondary cytoreductive surgery for recurrent epithelial ovarian cancer
    Nicole D Fleming
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, Los Angeles, CA 90048, USA
    Gynecol Oncol 121:249-52. 2011
  10. doi request reprint Post treatment surveillance of type II endometrial cancer patients
    Mae Zakhour
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, 8635 West 3rd Street, Suite 280W, Los Angeles, CA 90048, USA
    Gynecol Oncol 131:609-12. 2013

Detail Information

Publications17

  1. pmc Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas
    Christine S Walsh
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, David Geffen School of Medicine at UCLA, Los Angeles, California 90048, USA
    Clin Cancer Res 14:7645-51. 2008
    ..The importance of the BRCA gene products in maintaining genomic stability led us to hypothesize that BRCA-associated and sporadic ovarian cancers would have distinctive genetic profiles despite similarities in histologic appearance...
  2. doi request reprint Molecular signatures of ovarian cancer: from detection to prognosis
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Mol Diagn Ther 14:13-22. 2010
    ..In this review, we discuss the current state of biomarker development for the early detection of ovarian cancer and explore the continuing challenges to realizing this goal...
  3. ncbi request reprint Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Women s Cancer Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Boulevard, Suite 290W, Los Angeles, CA 90048, USA
    Gynecol Oncol 104:660-4. 2007
    ..The objective of this study was to examine the association between SNP309 and sporadic endometrial cancer risk...
  4. ncbi request reprint Contemporary progress in ovarian cancer screening
    Christine S Walsh
    Department of Obstetrics and Gynecology, University of California, Los Angeles, David Geffen School of Medicine at UCLA, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Suite 160W, Los Angeles, CA 90048, USA
    Curr Oncol Rep 9:485-93. 2007
    ..We review the current status and the challenges of ovarian cancer screening in the context of evidence-based principles that define a valuable cancer screening program...
  5. pmc Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening
    Christine S Walsh
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gynecol Oncol 116:516-21. 2010
    ..e. synchronous endometrial and ovarian cancer). Our study aims to estimate the prevalence of LS in these two populations...
  6. doi request reprint ERCC5 is a novel biomarker of ovarian cancer prognosis
    Christine S Walsh
    Department of Obstetrics and Gynecology, Cedars Sinai Women s Cancer Research Institute, Samuel Oschin Comprehensive Cancer Institute, David Geffen School of Medicine, University of California at Los Angeles, CA 90048, USA
    J Clin Oncol 26:2952-8. 2008
    ..Gene expression analyses were performed through microarray experiments. Candidate genes were tested for independent effects on survival using Cox proportional hazards models, Kaplan-Meier survival curves, and the log-rank test...
  7. ncbi request reprint Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene
    Claudia I Muller
    Division of Hematology Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Leuk Res 31:27-32. 2007
    ..Additionally, a previously unidentified PIK3CA pseudogene spanning exons 9-13 on chromosome 22 was discovered...
  8. doi request reprint Xeroderma pigmentosum complementation group C single-nucleotide polymorphisms in the nucleotide excision repair pathway correlate with prolonged progression-free survival in advanced ovarian cancer
    Nicole D Fleming
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, Los Angeles, California 90048, USA
    Cancer 118:689-97. 2012
    ..The objective of this study was to determine whether single-nucleotide polymorphisms (SNPs) in NER pathway genes could be markers of platinum response in ovarian cancer...
  9. doi request reprint CA125 surveillance increases optimal resectability at secondary cytoreductive surgery for recurrent epithelial ovarian cancer
    Nicole D Fleming
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, Los Angeles, CA 90048, USA
    Gynecol Oncol 121:249-52. 2011
    ..We hypothesized that a shorter time interval between CA125 elevation and SCS correlates with a higher likelihood of optimal resection among eligible patients...
  10. doi request reprint Post treatment surveillance of type II endometrial cancer patients
    Mae Zakhour
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, 8635 West 3rd Street, Suite 280W, Los Angeles, CA 90048, USA
    Gynecol Oncol 131:609-12. 2013
    ..Our objective was to determine the types of post treatment surveillance tests performed in our institution and the efficacy of these tests in detecting recurrence in type II endometrial cancer patients...
  11. doi request reprint Venous thromboembolism during primary treatment of ovarian clear cell carcinoma is associated with decreased survival
    Elena S Diaz
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, 8635 West 3rd Street, Suite 160W, Los Angeles, CA 90048, USA Electronic address
    Gynecol Oncol 131:541-5. 2013
    ..To determine the impact of venous thromboembolism (VTE) during primary treatment of ovarian clear cell carcinoma (OCCC) on survival...
  12. doi request reprint FBXW7 mutation in adult T-cell and B-cell acute lymphocytic leukemias
    Jee Hoon Song
    Department of Medicine, UCLA Cedars Sinai Research Institute, 110 George Burns Drive, Davis 5016, Los Angeles, CA 90034, USA
    Leuk Res 32:1751-5. 2008
    ..All mutations affected the FBXW7 target interacting domain. These observations suggest that disruption of FBXW7 has a role in several forms of lymphocytic leukemias and not exclusively T-cell acute lymphocytic leukemia...
  13. doi request reprint Is older age a poor prognostic factor in stage I and II endometrioid endometrial adenocarcinoma?
    Nicole D Fleming
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Women s Cancer Research Institute, Los Angeles, CA 90048, USA
    Gynecol Oncol 120:189-92. 2011
    ..The purpose of this study is to assess if age is an independent poor prognostic factor in endometrioid histologies...
  14. ncbi request reprint The prognostic significance of thrombocytosis in uterine papillary serous carcinomas
    Dimitry L Lerner
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cedars Sinai Medical Center, 8700 Beverly Blvd, Suite 160W, Los Angeles, CA 90048, USA
    Gynecol Oncol 104:91-4. 2007
    ..In light of the similarities between uterine papillary serous carcinomas (UPSC) and EOC, we sought to determine the incidence of thrombocytosis in UPSC and examine associations with clinico-pathologic features and survival...
  15. ncbi request reprint Discovery of epigenetically masked tumor suppressor genes in endometrial cancer
    Noriyuki Takai
    Division of Hematology Oncology, Cedars Sinai Medical Center University of California at Los Angeles School of Medicine, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Mol Cancer Res 3:261-9. 2005
    ..Our data suggest that C/ebpalpha and Tig1 function as tumor suppressor proteins in endometrial cancers and that their reexpression may be a therapeutic target...
  16. doi request reprint Predictors of resolution of complex atypical hyperplasia or grade 1 endometrial adenocarcinoma in premenopausal women treated with progestin therapy
    Kristine R Penner
    Department of Obstetrics and Gynecology, Olive View UCLA Medical Center, Sylmar, CA 91342, USA
    Gynecol Oncol 124:542-8. 2012
    ..To identify clinical and pathologic predictors of response to progestin treatment in premenopausal women with complex atypical hyperplasia (CAH) and Grade 1 endometrial adenocarcinoma (Grade 1 EA)...
  17. doi request reprint Stage II uterine papillary serous carcinoma: Carboplatin/paclitaxel chemotherapy improves recurrence and survival outcomes
    Amanda Nickles Fader
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A 81, Cleveland, Ohio 44195, USA
    Gynecol Oncol 112:558-62. 2009
    ..To determine recurrence patterns and survival outcomes of stage II uterine papillary serous carcinoma (UPSC) patients treated by various modalities with an emphasis on carboplatin/paclitaxel-based chemotherapy (CT)+/-radiotherapy (RT)...