Eric A Vasiliauskas

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. ncbi request reprint Case report: evidence for transplacental transfer of maternally administered infliximab to the newborn
    Eric A Vasiliauskas
    Inflammatory Bowel Disease Center, Division of Gastroenterology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Clin Gastroenterol Hepatol 4:1255-8. 2006
  2. ncbi request reprint Recent advances in the diagnosis and classification of inflammatory bowel disease
    Eric Vasiliauskas
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, 8631 West Third Street, Suite 245E, Los Angeles, CA 90048, USA
    Curr Gastroenterol Rep 5:493-500. 2003
  3. ncbi request reprint Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations
    Konstantinos A Papadakis
    Cedars Sinai Inflammatory Bowel Disease Center, Los Angeles, California, USA
    Inflamm Bowel Dis 13:524-30. 2007
  4. ncbi request reprint NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives
    Shane M Devlin
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gastroenterology 132:576-86. 2007
  5. doi request reprint Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease
    Andrew Ippoliti
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Inflamm Bowel Dis 16:1279-85. 2010
  6. ncbi request reprint Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease
    Jacob Spivak
    Division of Colon and Rectal Surgery, Department of Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Inflamm Bowel Dis 12:1122-30. 2006
  7. ncbi request reprint Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
    William S Mow
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Gastroenterology 126:414-24. 2004
  8. pmc Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis
    Gil Y Melmed
    Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Dis Colon Rectum 51:100-8. 2008
  9. doi request reprint A prospective analysis of clinical variables, serologic factors, and outcome of ileal pouch-anal anastomosis in patients with backwash ileitis
    Evan White
    Division of Colon and Rectal Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Dis Colon Rectum 53:987-94. 2010
  10. ncbi request reprint Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease
    Ling Mei
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gastroenterology 130:1078-85. 2006

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Case report: evidence for transplacental transfer of maternally administered infliximab to the newborn
    Eric A Vasiliauskas
    Inflammatory Bowel Disease Center, Division of Gastroenterology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Clin Gastroenterol Hepatol 4:1255-8. 2006
    ..As a result of heightened maternal concern triggered by recent labeling changes, infliximab levels were measured in the newborn of a mother treated with infliximab...
  2. ncbi request reprint Recent advances in the diagnosis and classification of inflammatory bowel disease
    Eric Vasiliauskas
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, 8631 West Third Street, Suite 245E, Los Angeles, CA 90048, USA
    Curr Gastroenterol Rep 5:493-500. 2003
    ....
  3. ncbi request reprint Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations
    Konstantinos A Papadakis
    Cedars Sinai Inflammatory Bowel Disease Center, Los Angeles, California, USA
    Inflamm Bowel Dis 13:524-30. 2007
    ..We examined the association between anti-CBir1 and clinical phenotypes and NOD2 variants in a large cohort of adult CD patients...
  4. ncbi request reprint NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives
    Shane M Devlin
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gastroenterology 132:576-86. 2007
    ..The aim of our study was to determine if defects in innate immunity are similarly associated with increased adaptive immune responses to microbial antigens in Crohn's disease patients...
  5. doi request reprint Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease
    Andrew Ippoliti
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Inflamm Bowel Dis 16:1279-85. 2010
    ....
  6. ncbi request reprint Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease
    Jacob Spivak
    Division of Colon and Rectal Surgery, Department of Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Inflamm Bowel Dis 12:1122-30. 2006
    ..This study examines the association between clinical features and seroreactivity to these microbial and auto-antigens in predicting a clinical response to fecal diversion...
  7. ncbi request reprint Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
    William S Mow
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Gastroenterology 126:414-24. 2004
    ..Our aim was to determine whether expression of antibodies against Crohn's disease-related bacterial sequence and Escherichia coli outer membrane porin C is associated with distinct phenotypic manifestations...
  8. pmc Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis
    Gil Y Melmed
    Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Dis Colon Rectum 51:100-8. 2008
    ..Preoperative predictors for Crohn's disease post-ileal pouch-anal anastomosis have not been prospectively defined...
  9. doi request reprint A prospective analysis of clinical variables, serologic factors, and outcome of ileal pouch-anal anastomosis in patients with backwash ileitis
    Evan White
    Division of Colon and Rectal Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Dis Colon Rectum 53:987-94. 2010
    ..We prospectively compared the outcomes of ileal pouch-anal anastomosis in colitis patients with backwash ileitis and colitis patients without backwash ileitis...
  10. ncbi request reprint Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease
    Ling Mei
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gastroenterology 130:1078-85. 2006
    ..The aim of this study was to determine whether there is familial aggregation and genetic determination of anti-OmpC expression in CD families...
  11. pmc Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression
    Marla C Dubinsky
    Department of Pediatrics, Genetics Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Gastroenterol 101:360-7. 2006
    ..We examined the association of immune responses to microbial antigens with disease behavior and prospectively determined the influence of immune reactivity on disease progression in pediatric CD patients...
  12. doi request reprint A prospective evaluation of the long-term outcome of ileal pouch-anal anastomosis in patients with inflammatory bowel disease-unclassified and indeterminate colitis
    Zuri A Murrell
    Department of Surgery, Division of Colon and Rectal Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Dis Colon Rectum 52:872-8. 2009
    ..The aim of this study was to prospectively evaluate the long-term outcome of ileal pouch-anal anastomosis in a closely monitored cohort of patients with ulcerative colitis or indeterminate colitis...
  13. ncbi request reprint High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy
    William S Mow
    Department of Medicine, Division of Gastroenterology, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Clin Gastroenterol Hepatol 2:309-13. 2004
    ..The aim of this study is to evaluate the utility of a TST as an adequate screen for TB exposure in patients with inflammatory bowel disease (IBD)...
  14. ncbi request reprint Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis?
    Stefanie J Schluender
    Division of Colon and Rectal Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, 8737 Beverly Boulevard, Suite 101, Los Angeles, California 90048, USA
    Dis Colon Rectum 50:1747-53. 2007
    ..This study was designed to compare short-term complications in patients with ulcerative colitis who were treated with and without infliximab before colectomy...
  15. ncbi request reprint Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study
    Gil Y Melmed
    Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California Los Angeles, California, USA
    Clin Gastroenterol Hepatol 5:602-8; quiz 525. 2007
    ..Identification of predictors of a diagnostic change could potentially impact the management of patients with colonic inflammation. Our aim was to characterize clinical and serologic predictors of a change in diagnosis from UC to CD...
  16. ncbi request reprint Treatment with infliximab is associated with increased markers of bone formation in patients with Crohn's disease
    Maria T Abreu
    Department of Medicine, Division of Gastroenterology, Inflammatory Bowel Disease Center, Mount Sinai School of Medicine, New York, NY, USA
    J Clin Gastroenterol 40:55-63. 2006
    ..The aim of this study was to assess the ability of treatment with the TNF-alpha antagonist infliximab to increase bone formation as measured by surrogate markers of bone turnover in patients with active CD...
  17. ncbi request reprint Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease
    William S Mow
    Inflammatory Bowel Disease Center, Los Angeles, California, USA
    Clin Gastroenterol Hepatol 2:31-40. 2004
    ..The aim of this study is to assess the clinical utility of WCE in the evaluation of patients with known or suspected inflammatory bowel disease (IBD)...
  18. doi request reprint Surgical outcome of ileal pouch-anal anastomosis when used intentionally for well-defined Crohn's disease
    Quy Le
    Division of Colon and Rectal Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Inflamm Bowel Dis 19:30-6. 2013
    ..Crohn's disease (CD) is considered a contraindication to ileal pouch--anal anastomosis (IPAA). In this study, we compare outcomes of CD and ulcerative colitis (UC) patients undergoing IPAA...
  19. ncbi request reprint Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab
    Konstantinos A Papadakis
    Division of Gastroenterology, Department of Medicine, Inflammatory Bowel Disease Center, 8631 W Third Street, Suite 430E, Los Angeles, CA 90048, USA
    Am J Gastroenterol 100:75-9. 2005
    ..The aim of our study was to examine the safety and efficacy of adalimumab (D2E7), a fully humanized anti-TNF-alpha Ab, in CD patients who had experienced an attenuated response to infliximab...
  20. ncbi request reprint Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease
    Stephen A Geller
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 28:1204-11. 2004
    ..6-TG-related hepatotoxicity, including liver biochemistry value elevations, sinusoidal collagen deposition on electron microscopy, and veno-occlusive disease, have been described related to its use as therapy for neoplastic disease...
  21. ncbi request reprint A pilot study of adalimumab in infliximab-allergic patients
    Adrienne Youdim
    Department of Medicine, Division of Gastroenterology, Inflammatory Bowel Disease Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 10:333-8. 2004
    ..Based on these preliminary data, adalimumab may be a safe and effective substitute for infliximab-allergic patients. Individuals who have been exposed to human antibodies may be sensitized to other human antibodies such as adalimumab...
  22. pmc Genetic predictors of medically refractory ulcerative colitis
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 16:1830-40. 2010
    ..The aim of this study was to use a genome-wide association study (GWAS) in a well-characterized cohort of UC patients to identify genetic variation that contributes to MR-UC...
  23. doi request reprint Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease
    Gil Y Melmed
    Department of Medicine, Cedars Sinai Medical Center, University of California, Los Angeles, California 90048, USA
    Am J Gastroenterol 105:148-54. 2010
    ..We aimed to assess the impact of immunosuppression on immune responses to pneumococcal vaccination in patients with IBD...
  24. doi request reprint Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale
    Bijal Surti
    F Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, 8635 W 3rd St 960 Wv, Los Angeles, CA 90048, USA
    Dig Dis Sci 58:1313-21. 2013
    ..A numeric rating scale (NRS) is a quick, inexpensive, and convenient patient-reported outcome that can capture the patient's overall perception of health...
  25. ncbi request reprint Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine
    Marla C Dubinsky
    Department of Medicine, Division of Gastroenterology, Cedars Sinai Medical Center, UCLA, Los Angeles, California 90048, USA
    Am J Gastroenterol 98:1058-63. 2003
    ..The aim of this study was to determine if hypersensitivity reactions to 6-MP/AZA reoccur with 6-TG therapy...
  26. doi request reprint Colorectal cancer screening and surveillance in Crohn's colitis
    Robert J Basseri
    Department of Medicine and Division of Gastroenterology, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Crohns Colitis 6:824-9. 2012
    ..To assess colonoscopic screening and surveillance for detecting neoplasia in patients with long-standing colonic Crohn's disease (CD)...
  27. ncbi request reprint Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy
    Sunita Shastri
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Arch Pathol Lab Med 128:49-53. 2004
    ..Recently, 6-thioguanine has been used to treat patients with inflammatory bowel disease who have been resistant to other forms of therapy...
  28. ncbi request reprint 6-thioguanine can cause serious liver injury in inflammatory bowel disease patients
    Marla C Dubinsky
    Pediatric Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, 8635 West Third Street, Suite 1165W, Los Angeles, California 90048, USA
    Gastroenterology 125:298-303. 2003
    ..The aim of this study was to describe the association between 6-TG and NRH in IBD...
  29. doi request reprint Capsule endoscopy in patients with Crohn's disease: diagnostic yield and safety
    Shahab Mehdizadeh
    Division of Gastroenterology, Cedars Sinai Medical Center, Los Angeles, California, USA
    Gastrointest Endosc 71:121-7. 2010
    ..Capsule endoscopy (CE) is increasingly used in patients with suspected or known Crohn's disease (CD)...
  30. ncbi request reprint Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses
    Gil Y Melmed
    Department of Medicine, Division of Gastroenterology, Cedars Sinai Medical Center Los Angeles, California 90048, USA
    Am J Gastroenterol 101:1834-40. 2006
    ..We aimed to assess exposure risk and immunization status among patients receiving care in an IBD specialty clinic...
  31. ncbi request reprint The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease
    Robin Matuk
    Department of Medicine, Division of Gastroenterology, Cedars Sinai Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Inflamm Bowel Dis 10:352-6. 2004
    ..Treatment with COX-2 inhibitors is associated with a high incidence of exacerbation of the underlying IBD and GI-related complications...
  32. ncbi request reprint Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis
    Aderet Okon
    Division of Colon and Rectal Surgery, Department of Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am Surg 71:821-6. 2005
    ..03). The incidence of CP was significantly higher after IPAA in UC patients having thrombocytosis before surgery compared to UC patients having a normal platelet count before surgery...
  33. ncbi request reprint Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    Maria T Abreu
    Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Gastroenterology 123:679-88. 2002
    ..NOD2 gene mutations in CD have been described recently and may alter innate immune responses. We hypothesized that NOD2 mutations may be associated with distinct phenotypic expressions of CD...
  34. pmc MAGI2 genetic variation and inflammatory bowel disease
    Dermot P B McGovern
    Medical Genetics Institute and Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Inflamm Bowel Dis 15:75-83. 2009
    ..Our aim was to test MAGI2 variants for association with IBD and also their role in determining intermediate hereditary phenotypes defined by antibody production to microbial antigens...
  35. pmc Increased immune reactivity predicts aggressive complicating Crohn's disease in children
    Marla C Dubinsky
    Department of Pediatrics, IBD Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Clin Gastroenterol Hepatol 6:1105-11. 2008
    ..The aims of this study were to determine whether immune responses and/or CARD15 variants are associated with complicated disease phenotypes and predict disease progression...
  36. ncbi request reprint Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease
    Stephan R Targan
    Cedars Sinai Inflammatory Bowel Disease Center, Los Angeles, California 90048, USA
    Gastroenterology 128:2020-8. 2005
    ....
  37. pmc Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis
    Phillip Fleshner
    Division of Colon and Rectal Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Clin Gastroenterol Hepatol 6:561-8. 2008
    ..The aim of this study was to assess associations of preoperative perinuclear antineutrophil cytoplasmic antibody (pANCA) and anti-CBir1 flagellin on AP or CP development...
  38. ncbi request reprint Serologic responses in indeterminate colitis patients before ileal pouch-anal anastomosis may determine those at risk for continuous pouch inflammation
    Thomas Hui
    Division of Colon and Rectal Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Dis Colon Rectum 48:1254-62. 2005
    ..We examined whether preoperative serologic responses to these antigens were associated with Crohn's disease in indeterminate colitis patients after ileal pouch-anal anastomosis...
  39. pmc Genome-wide association identifies multiple ulcerative colitis susceptibility loci
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Nat Genet 42:332-7. 2010
    ..These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis...
  40. doi request reprint New clinical method for distinguishing D-IBS from other gastrointestinal conditions causing diarrhea: the LA/IBS diagnostic strategy
    Mark Pimentel
    GI Motility Program, Cedars Sinai Medical Center, 8730 Alden Drive, Suite 225E, Los Angeles, CA 90048, USA
    Dig Dis Sci 55:145-9. 2010
    ..81; specificity = 0.60). The use of this simple tool that identifies an irregularly irregular bowel form and function is successful in separating D-IBS from non-IBS subjects...
  41. ncbi request reprint 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
    Marla C Dubinsky
    Division of Gastroenterology and Genetics, Department of Medicine and Pediatrics, Cedars Sinai Medical Center, UCLA, Los Angeles, California 90048, USA
    Gastroenterology 122:904-15. 2002
    ..The objectives of this study were to determine whether dose escalation optimizes both 6-TGN levels and efficacy in patients failing therapy because of subtherapeutic 6-TGN levels and its effect on TPMT...
  42. pmc Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Hum Mol Genet 19:3468-76. 2010
    ..001). These findings strongly implicate this locus in CD susceptibility and highlight the role of the mucus layer in the development of CD...
  43. ncbi request reprint A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis
    Phillip Fleshner
    Division of Colon and Rectal Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Clin Gastroenterol Hepatol 5:952-8; quiz 887. 2007
    ..The aim of this study was to identify important clinical risk factors associated with AP or CP...
  44. doi request reprint Preoperative wireless capsule endoscopy does not predict outcome after ileal pouch-anal anastomosis
    Zuri Murrell
    Division of Colon and Rectal Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
    Dis Colon Rectum 53:293-300. 2010
    ..This study examined the value of preoperative wireless capsule endoscopy in predicting outcome of ileal pouch-anal anastomosis in patients with ulcerative colitis or indeterminate colitis...
  45. pmc Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
    Dermot P B McGovern
    Medical Genetics Institute and Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 15:883-9. 2009
    ..Genetic variants in the IL23R and IL12B have been associated with CD susceptibility. We investigated 10 genes within the IL23/IL17 pathway in a case-control study of 763 CD cases and 254 healthy controls...