Dhruv Sareen

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. pmc Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    PLoS ONE 7:e39113. 2012
  2. pmc Patient-Derived Skeletal Dysplasia Induced Pluripotent Stem Cells Display Abnormal Chondrogenic Marker Expression and Regulation by BMP2 and TGFβ1
    Biagio Saitta
    1 Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California
    Stem Cells Dev 23:1464-78. 2014
  3. pmc Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, CA, 90048 Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA, 90048
    J Comp Neurol 522:2707-28. 2014
  4. pmc Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Sci Transl Med 5:208ra149. 2013
  5. pmc A simple alkaline method for decellularizing human amniotic membrane for cell culture
    Mehrnoosh Saghizadeh
    Eye Program, Cedars Sinai Medical Center, Los Angeles, California, United States of America Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, California, United States of America Departments of Biomedical Sciences, Surgery, and Neurosurgery, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 8:e79632. 2013
  6. pmc Neonatal immune-tolerance in mice does not prevent xenograft rejection
    Virginia B Mattis
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Exp Neurol 254:90-8. 2014

Collaborators

  • David L Rimoin
  • Deborah Krakow
  • John Ravits
  • Robert H Baloh
  • Allison D Ebert
  • Daniel H Cohn
  • Clive N Svendsen
  • Loren Ornelas
  • Biagio Saitta
  • Virginia B Mattis
  • Anais Sahabian
  • Mehrnoosh Saghizadeh
  • Jenna Passarini
  • Colton Tom
  • JACK REIDLING
  • Leslie M Thompson
  • Ksenija Bernau
  • Dustin R Wakeman
  • Shilpa Argade
  • Hemraj B Dodiya
  • Sylvia Y Yeung
  • Jeffrey H Kordower
  • Andrew H Tran
  • Slobodan D Dimitrijevich
  • Homayon Ghiasi
  • Yaron S Rabinowitz
  • Ezra Maguen
  • William J Brunken
  • Alexander V Ljubimov
  • Andrei A Kramerov
  • Chantelle A Ghiam
  • Katerina Jirsova
  • Michael A Winkler
  • David M Hemmati

Detail Information

Publications6

  1. pmc Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    PLoS ONE 7:e39113. 2012
    ..Together, these data further validate this human stem cell model of SMA, suggesting that specific inhibitors of apoptotic pathways may be beneficial for patients...
  2. pmc Patient-Derived Skeletal Dysplasia Induced Pluripotent Stem Cells Display Abnormal Chondrogenic Marker Expression and Regulation by BMP2 and TGFβ1
    Biagio Saitta
    1 Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California
    Stem Cells Dev 23:1464-78. 2014
    ....
  3. pmc Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, CA, 90048 Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA, 90048
    J Comp Neurol 522:2707-28. 2014
    ..These results suggest that human iNPCs behave like fNPCs and could thus be a valuable alternative for cellular regenerative therapies of neurological diseases. J. Comp. Neurol. 522:2707-2728, 2014. © 2014 Wiley Periodicals, Inc. ..
  4. pmc Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion
    Dhruv Sareen
    Regenerative Medicine Institute, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Sci Transl Med 5:208ra149. 2013
    ..These data show that patient-derived motor neurons can be used to delineate pathogenic events in ALS. ..
  5. pmc A simple alkaline method for decellularizing human amniotic membrane for cell culture
    Mehrnoosh Saghizadeh
    Eye Program, Cedars Sinai Medical Center, Los Angeles, California, United States of America Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, California, United States of America Departments of Biomedical Sciences, Surgery, and Neurosurgery, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 8:e79632. 2013
    ..This simple, fast and reliable method can be used to standardize decellularized amniotic membrane preparations for expansion of limbal stem cells in vitro before transplantation to patients. ..
  6. pmc Neonatal immune-tolerance in mice does not prevent xenograft rejection
    Virginia B Mattis
    Regenerative Medicine Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Exp Neurol 254:90-8. 2014
    ..We also address specific challenges associated with the generation of humanized mouse models of disease. ..