Research Topics
Genomes and Genes
Species | Gil Y MelmedSummaryAffiliation: Cedars-Sinai Medical Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitisGil Y Melmed
Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Dis Colon Rectum 51:100-8. 2008..Preoperative predictors for Crohn's disease post-ileal pouch-anal anastomosis have not been prospectively defined...
Quality indicators for inflammatory bowel disease: development of process and outcome measuresGil Y Melmed
Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
Inflamm Bowel Dis 19:662-8. 2013..The RAND/UCLA appropriateness method was used to develop a set of process and outcome QIs to define quality of care for IBD...- Anti-aging therapy with human growth hormone associated with metastatic colon cancer in a patient with Crohn's colitisGil Y Melmed
Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California, Los Angeles, California 90048, USA
Clin Gastroenterol Hepatol 6:360-3. 2008..The nonapproved use of human growth hormone (HGH) for anti-aging has been increasing. Theoretical concerns for neoplastic potentiation by HGH have been raised, but not proven clinically... - A new method for endoscopic closure of gastrocolonic fistula: novel application of a cardiac septal defect closure device (with video)Gil Y Melmed
Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California, Los Angeles, California 90048, USA
Gastrointest Endosc 70:542-5. 2009..Gastrocolonic fistula after percutaneous endoscopic gastrostomy PEG tube placement is an uncommon but serious complication. These fistulous tracts are often fibrotic and frequently require surgical intervention... - Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel diseaseGil Y Melmed
Department of Medicine, Cedars Sinai Medical Center, University of California, Los Angeles, California 90048, USA
Am J Gastroenterol 105:148-54. 2010..We aimed to assess the impact of immunosuppression on immune responses to pneumococcal vaccination in patients with IBD... - Future biologic targets for IBD: potentials and pitfallsGil Y Melmed
Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, 8635 West 3rd Street, 960 W Los Angeles, CA 90048, USA
Nat Rev Gastroenterol Hepatol 7:110-7. 2010..Future biologic drug development will benefit from the early identification of subsets of patients who are most likely to respond to therapy by use of biological markers of genetic susceptibility or immunologic susceptibility... - The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit allGil Y Melmed
Cedars Sinai Medical Center, Los Angeles, California 90048, USA
Clin Gastroenterol Hepatol 8:655-9. 2010..We applied the RAND/University of California Los Angeles Appropriateness Method toward establishing appropriateness of concomitant immunomodulators and anti-TNF therapies for Crohn's disease... - Vaccination strategies for patients with inflammatory bowel disease on immunomodulators and biologicsGil Y Melmed
Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Inflamm Bowel Dis 15:1410-6. 2009..This review discusses the rationale for currently recommended vaccinations, as well as issues pertaining to vaccine safety and immunogenicity in immunosuppressed patients with inflammatory bowel disease and their household contacts... - A prospective analysis of clinical variables, serologic factors, and outcome of ileal pouch-anal anastomosis in patients with backwash ileitisEvan White
Division of Colon and Rectal Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA
Dis Colon Rectum 53:987-94. 2010..We prospectively compared the outcomes of ileal pouch-anal anastomosis in colitis patients with backwash ileitis and colitis patients without backwash ileitis... - A prospective evaluation of the long-term outcome of ileal pouch-anal anastomosis in patients with inflammatory bowel disease-unclassified and indeterminate colitisZuri A Murrell
Department of Surgery, Division of Colon and Rectal Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California, USA
Dis Colon Rectum 52:872-8. 2009..The aim of this study was to prospectively evaluate the long-term outcome of ileal pouch-anal anastomosis in a closely monitored cohort of patients with ulcerative colitis or indeterminate colitis... 
Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control studyGil Y Melmed
Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California Los Angeles, California, USA
Clin Gastroenterol Hepatol 5:602-8; quiz 525. 2007..Identification of predictors of a diagnostic change could potentially impact the management of patients with colonic inflammation. Our aim was to characterize clinical and serologic predictors of a change in diagnosis from UC to CD...- Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease?Evan C White
Division of Colon and Rectal Surgery, Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California, USA
Dis Colon Rectum 55:563-8. 2012..Unplanned hospital readmission is considered to be an index of quality surgical care... - Patients with inflammatory bowel disease are at risk for vaccine-preventable illnessesGil Y Melmed
Department of Medicine, Division of Gastroenterology, Cedars-Sinai Medical Center Los Angeles, California 90048, USA
Am J Gastroenterol 101:1834-40. 2006..Efforts to improve immunization status among patients with IBD and other chronic, immune-mediated conditions are needed... - Variants in ZNF365 isoform D are associated with Crohn's diseaseTalin Haritunians
Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Gut 60:1060-7. 2011..Genome-wide association studies have identified multiple Crohn's disease (CD) susceptibility loci, including association with non-coding intergenic single-nucleotide polymorphisms (SNPs) at 10q21... - Genetic predictors of medically refractory ulcerative colitisTalin Haritunians
Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Inflamm Bowel Dis 16:1830-40. 2010..The aim of this study was to use a genome-wide association study (GWAS) in a well-characterized cohort of UC patients to identify genetic variation that contributes to MR-UC... - NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relativesShane M Devlin
Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
Gastroenterology 132:576-86. 2007..The aim of our study was to determine if defects in innate immunity are similarly associated with increased adaptive immune responses to microbial antigens in Crohn's disease patients... - Colorectal cancer screening and surveillance in Crohn's colitisRobert J Basseri
Department of Medicine and Division of Gastroenterology, Cedars Sinai Medical Center, Los Angeles, CA, USA
J Crohns Colitis 6:824-9. 2012..To assess colonoscopic screening and surveillance for detecting neoplasia in patients with long-standing colonic Crohn's disease (CD)... - New clinical method for distinguishing D-IBS from other gastrointestinal conditions causing diarrhea: the LA/IBS diagnostic strategyMark Pimentel
GI Motility Program, Cedars Sinai Medical Center, 8730 Alden Drive, Suite 225E, Los Angeles, CA 90048, USA
Dig Dis Sci 55:145-9. 2010..81; specificity = 0.60). The use of this simple tool that identifies an irregularly irregular bowel form and function is successful in separating D-IBS from non-IBS subjects... - Are immunosuppressive medications associated with decreased responses to routine immunizations? A systematic reviewNikhil Agarwal
Division of Gastroenterology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, United States
Vaccine 30:1413-24. 2012..Vaccination may be a way to prevent a variety of infections but vaccine responses among patients receiving immunosuppressive therapies have been variable... - Controversies in ulcerative colitis: a survey comparing decision making of experts versus community gastroenterologistsBrennan M R Spiegel
Veteran s Administration Greater Los Angeles Healthcare System, Los Angeles, California, USA
Clin Gastroenterol Hepatol 7:168-74, 174.e1. 2009..We performed a national vignette survey to measure variations in decision-making in areas of controversy... - High-dose perioperative corticosteroids in steroid-treated patients undergoing major colorectal surgery: necessary or overkill?Karen N Zaghiyan
Division of Colorectal Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
Am J Surg 204:481-6. 2012..However, there is no evidence to support this practice... - Genome-wide association identifies multiple ulcerative colitis susceptibility lociDermot P B McGovern
Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
Nat Genet 42:332-7. 2010..These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis... - Capsule endoscopy: practical applicationsGil Y Melmed
Divison of Gastroenterology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
Clin Gastroenterol Hepatol 3:411-22. 2005..We discuss safety concerns, optimal preparation for the procedure, diagnostic utility as compared to conventional methods, indications for capsule endoscopy, and outcomes... - New insights into the pathogenesis of inflammatory bowel diseaseGil Y Melmed
Department of Medicine, Division of Gastroenterology, Inflammatory Bowel Disease Center, Mount Sinai School of Medicine, 1190 Fifth Avenue, New York, NY 10029, USA
Curr Gastroenterol Rep 6:474-81. 2004..In this review we summarize these key developments in the pathophysiology of inflammatory bowel disease and attempt to ascribe clinical relevance where applicable... - Quality of life at the end of life: trends in patients with metastatic prostate cancerGil Y Melmed
Department of Urology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90095-1738, USA
Urology 59:103-9. 2002..Further investigation may help identify specific patient characteristics associated with more rapid declines; this will help focus attention on enhancing patients' quality of life as death approaches... - The impact of medical therapy for inflammatory bowel disease on pregnancy outcomePeter W Simpson
Am J Gastroenterol 103:805-6. 2008 - Proximal small intestinal CD detected by CEGil Y Melmed
Gastrointest Endosc 68:202-3; author reply 203-4. 2008 - Certolizumab pegolGil Y Melmed
Nat Rev Drug Discov 7:641-2. 2008..In April 2008, certolizumab pegol (Cimzia; UCB), a tumour-necrosis factor blocker, was approved by the US FDA for the treatment of adult patients with moderate-to-severe Crohn's disease who have not responded to conventional therapies...