Gislaine A Martins
Affiliation: Cedars-Sinai Medical Center
- Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survivalGislaine A Martins
Department of Microbiology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Exp Med 205:1959-65. 2008..This activity of Blimp-1 is important for cytokine deprivation-induced T cell death and for attenuating T cell proliferation in antigen-specific responses both in vitro and in vivo...
- Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expressionLuisa Cimmino
The Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J Immunol 181:2338-47. 2008..Our data provide evidence that Blimp-1 functions in Th2 cells to reinforce Th2 differentiation by repressing critical Th1 genes...
- Multiple roles for Blimp-1 in B and T lymphocytesDavid Savitsky
Department of Biological Sciences, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Adv Exp Med Biol 596:9-30. 2007
- Transcriptional repressor Blimp-1 regulates T cell homeostasis and functionGislaine A Martins
Department of Microbiology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Nat Immunol 7:457-65. 2006..These results emphasize a crucial function for Blimp-1 in controlling T cell homeostasis and activation...