Tao Sheng Li

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. pmc Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair
    Tao Sheng Li
    Cedars Sinai Heart Institute, Los Angeles, California 90048, USA
    Stem Cells 28:2088-98. 2010
  2. pmc Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells
    Tao Sheng Li
    Cedars Sinai Heart Institute, Los Angeles, California, USA
    J Am Coll Cardiol 59:942-53. 2012
  3. doi Magnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusion
    Ke Cheng
    Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    Cell Transplant 21:1121-35. 2012
  4. pmc Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair
    Tao Sheng Li
    The Cedars Sinai Heart Institute, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Cardiovasc Res 89:157-65. 2011
  5. pmc Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction
    Ke Cheng
    The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circ Res 106:1570-81. 2010
  6. doi Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel
    Ke Cheng
    The Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    Biomaterials 33:5317-24. 2012
  7. pmc Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells
    Konstantinos Malliaras
    Cedars Sinai Heart Institute, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Circulation 125:100-12. 2012
  8. doi Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction
    Shuo Tsan Lee
    Cedars Sinai Heart Institute, Los Angeles, California 90048, USA
    J Am Coll Cardiol 57:455-65. 2011
  9. pmc Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells
    Tao Sheng Li
    The Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Stem Cells 28:1178-85. 2010
  10. doi Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    Isotta Chimenti
    Cedars Sinai Heart Institute, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Circ Res 106:971-80. 2010

Collaborators

  • Eduardo Marban
  • Glenn D Prestwich
  • Hideo Kusuoka
  • Ke Cheng
  • Konstantinos Malliaras
  • Giselle Galang
  • Yiqiang Zhang
  • Baiming Sun
  • Linda Marb├ín
  • John Terrovitis
  • Shuo Tsan Lee
  • Isotta Chimenti
  • Rachel R Smith
  • Florian Schoenhoff
  • Agnieszka Blusztajn
  • Christiane Houde
  • Jennifer Van Eyk
  • Jeremy Smith
  • Noriko Matsushita
  • Tarun Chakravarty
  • Thomas I Zarembinski
  • Daniel Luthringer
  • Deliang Shen
  • Anthony J White
  • Kristine Yee
  • Charles Steenbergen
  • Satoshi Matsushita
  • Raj Makkar
  • Sinan Simsir
  • Rachel Ruckdeschel Smith
  • Elisa Messina
  • Gary Gerstenblith
  • Alessandro Giacomello
  • Darryl R Davis

Detail Information

Publications10

  1. pmc Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair
    Tao Sheng Li
    Cedars Sinai Heart Institute, Los Angeles, California 90048, USA
    Stem Cells 28:2088-98. 2010
    ..These changes underlie an increase in cell survival and more potent augmentation of global function following implantation into the infarcted heart...
  2. pmc Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells
    Tao Sheng Li
    Cedars Sinai Heart Institute, Los Angeles, California, USA
    J Am Coll Cardiol 59:942-53. 2012
    ..The goal of this study was to conduct a direct head-to-head comparison of different stem cell types in vitro for various assays of potency and in vivo for functional myocardial repair in the same mouse model of myocardial infarction...
  3. doi Magnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusion
    Ke Cheng
    Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    Cell Transplant 21:1121-35. 2012
    ..In a rat model of ischemia/reperfusion injury, magnetically enhanced intracoronary cell delivery is safe and improves cell therapy outcomes...
  4. pmc Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair
    Tao Sheng Li
    The Cedars Sinai Heart Institute, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Cardiovasc Res 89:157-65. 2011
    ..Here we attempt to avoid aneuploidy and improve cell quality by expanding human cardiac stem cells in physiological low-oxygen (5% O(2)) conditions, rather than in traditional culture in a general CO(2) incubator (20% O(2))...
  5. pmc Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction
    Ke Cheng
    The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circ Res 106:1570-81. 2010
    ..The success of cardiac stem cell therapies is limited by low cell retention, due at least in part to washout via coronary veins...
  6. doi Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel
    Ke Cheng
    The Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    Biomaterials 33:5317-24. 2012
    ..A CDC/hydrogel formulation suitable for catheter-based intramyocardial injection exhibits superior engraftment and functional benefits relative to naked CDCs...
  7. pmc Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells
    Konstantinos Malliaras
    Cedars Sinai Heart Institute, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Circulation 125:100-12. 2012
    ..The use of allogeneic CDCs, if safe and effective, would obviate such limitations. We compared syngeneic and allogeneic CDC transplantation in rats from immunologically-mismatched inbred strains...
  8. doi Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction
    Shuo Tsan Lee
    Cedars Sinai Heart Institute, Los Angeles, California 90048, USA
    J Am Coll Cardiol 57:455-65. 2011
    ....
  9. pmc Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells
    Tao Sheng Li
    The Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Stem Cells 28:1178-85. 2010
    ..The concept of an "oxidative optimum" for genomic stability has broad implications for stem cell biology and carcinogenesis...
  10. doi Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    Isotta Chimenti
    Cedars Sinai Heart Institute, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Circ Res 106:971-80. 2010
    ..Most prominent among these are direct heart muscle and blood vessel regeneration from transplanted cells, as opposed to paracrine enhancement of tissue preservation and/or recruitment of endogenous repair...