S C Jordan

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. doi request reprint Desensitizing the broadly human leukocyte antigen-sensitized patient awaiting deceased donor kidney transplantation
    S C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Transplant Proc 44:60-1. 2012
  2. ncbi request reprint Novel immunotherapeutic approaches to improve rates and outcomes of transplantation in sensitized renal allograft recipients
    Stanley C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Discov Med 13:235-45. 2012
  3. pmc Advances in diagnosing and managing antibody-mediated rejection
    Stanley C Jordan
    The Transplant Immunotherapy Program, Comprehensive Transplant Center, Los Angeles, CA 90048, USA
    Pediatr Nephrol 25:2035-45; quiz 2045-8. 2010
  4. ncbi request reprint Intravenous immune globulin treatment inhibits crossmatch positivity and allows for successful transplantation of incompatible organs in living-donor and cadaver recipients
    S C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Transplantation 76:631-6. 2003
  5. doi request reprint B-cell immunotherapeutics: emerging roles in solid organ transplantation
    Stanley C Jordan
    Comprehensive Transplant Center, Kidney Transplant Program and Transplant Immunotherapy Program, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Curr Opin Organ Transplant 16:416-24. 2011
  6. ncbi request reprint Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal disease: report of the NIH IG02 trial
    Stanley C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, 8635 W 3rd Street, Suite 590W, Los Angeles, CA 90048, USA
    J Am Soc Nephrol 15:3256-62. 2004
  7. ncbi request reprint Treatment of active cytomegalovirus disease with oral ganciclovir in renal allograft recipients: monitoring efficacy with quantitative cytomegalovirus polymerase chain reaction
    Stanley C Jordan
    Kidney Transplant Program and Transplant Immunology, Cedars Sinai Medical Center, UCLA School of Medicine, LA, CA 90048, USA
    Am J Transplant 2:671-3. 2002
  8. doi request reprint Regulation of immunity and inflammation by intravenous immunoglobulin: relevance to solid organ transplantation
    Stanley C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Expert Rev Clin Immunol 7:341-8. 2011
  9. doi request reprint Clinical aspects of intravenous immunoglobulin use in solid organ transplant recipients
    S C Jordan
    Comprehensive Transplant Center Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Transplant 11:196-202. 2011
  10. ncbi request reprint Post-transplant therapy with high-dose intravenous gammaglobulin: Applications to treatment of antibody-mediated rejection
    Stanley C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
    Pediatr Transplant 9:155-61. 2005

Collaborators

Detail Information

Publications67

  1. doi request reprint Desensitizing the broadly human leukocyte antigen-sensitized patient awaiting deceased donor kidney transplantation
    S C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Transplant Proc 44:60-1. 2012
    ..Patient and graft survival data are also presented as is an analysis of the safety of IVIG + rituximab in sensitized patients...
  2. ncbi request reprint Novel immunotherapeutic approaches to improve rates and outcomes of transplantation in sensitized renal allograft recipients
    Stanley C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Discov Med 13:235-45. 2012
    ..Here we discuss the importance of B-cells and DSAs as mediators of allograft injury and the evolution of therapies aimed at reducing their impact on allograft survival...
  3. pmc Advances in diagnosing and managing antibody-mediated rejection
    Stanley C Jordan
    The Transplant Immunotherapy Program, Comprehensive Transplant Center, Los Angeles, CA 90048, USA
    Pediatr Nephrol 25:2035-45; quiz 2045-8. 2010
    ..Newer approaches to treating AMR include using the proteosome inhibitor (bortezomib), which induces apoptosis in plasma cells, and eculizumab (anti-C5, anticomplement monoclonal antibody)...
  4. ncbi request reprint Intravenous immune globulin treatment inhibits crossmatch positivity and allows for successful transplantation of incompatible organs in living-donor and cadaver recipients
    S C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Transplantation 76:631-6. 2003
    ..Here, we report a novel approach using intravenous immune globulin to modulate anti-HLA antibody and improve the chances for successful transplantation...
  5. doi request reprint B-cell immunotherapeutics: emerging roles in solid organ transplantation
    Stanley C Jordan
    Comprehensive Transplant Center, Kidney Transplant Program and Transplant Immunotherapy Program, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Curr Opin Organ Transplant 16:416-24. 2011
    ..These advances clearly have implications for patients receiving solid organ transplants, especially those who are ABO incompatible, sensitized to human leukocyte antigen (HLA) pretransplant, or develop anti-HLA antibodies posttransplant...
  6. ncbi request reprint Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal disease: report of the NIH IG02 trial
    Stanley C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, 8635 W 3rd Street, Suite 590W, Los Angeles, CA 90048, USA
    J Am Soc Nephrol 15:3256-62. 2004
    ..Transplant rates for highly sensitized patients with ESRD awaiting kidney transplants are improved with IVIG therapy...
  7. ncbi request reprint Treatment of active cytomegalovirus disease with oral ganciclovir in renal allograft recipients: monitoring efficacy with quantitative cytomegalovirus polymerase chain reaction
    Stanley C Jordan
    Kidney Transplant Program and Transplant Immunology, Cedars Sinai Medical Center, UCLA School of Medicine, LA, CA 90048, USA
    Am J Transplant 2:671-3. 2002
    ..Our data suggest that oral ganciclovir treatment, coupled with careful CMV-PCR monitoring, may be a reasonable alternative to long-term intravenous ganciclovir...
  8. doi request reprint Regulation of immunity and inflammation by intravenous immunoglobulin: relevance to solid organ transplantation
    Stanley C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Expert Rev Clin Immunol 7:341-8. 2011
    ..Here, we discuss these important advancements and their relevance to transplant medicine...
  9. doi request reprint Clinical aspects of intravenous immunoglobulin use in solid organ transplant recipients
    S C Jordan
    Comprehensive Transplant Center Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Transplant 11:196-202. 2011
    ..In addition, we address the risk of adverse events associated with IVIG use in sensitized end-stage renal disease and transplant patients...
  10. ncbi request reprint Post-transplant therapy with high-dose intravenous gammaglobulin: Applications to treatment of antibody-mediated rejection
    Stanley C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
    Pediatr Transplant 9:155-61. 2005
    ..Further clinical trials are necessary to prove efficacy for treatment of AMR...
  11. ncbi request reprint Current approaches to treatment of antibody-mediated rejection
    Stanley C Jordan
    Renal Transplant Program, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Pediatr Transplant 9:408-15. 2005
    ..However, much work needs to be done to better understand the immunologic processes leading to AMR and how current therapies can be best used to effectively prevent and treat it...
  12. ncbi request reprint Intravenous gammaglobulin (IVIG): a novel approach to improve transplant rates and outcomes in highly HLA-sensitized patients
    S C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, UCLA School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    Am J Transplant 6:459-66. 2006
    ..These advancements have enabled transplantation of patients previously considered untransplantable. These studies and relevant mechanism(s) of action will be discussed here...
  13. doi request reprint Intravenous immunoglobulin a natural regulator of immunity and inflammation
    Stanley C Jordan
    Department of Medicine, Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Transplantation 88:1-6. 2009
    ..Here, we discuss these important advancements and how this knowledge applies to desensitization protocols and to the treatment of antibody-mediated rejection...
  14. ncbi request reprint Presensitization: the problem and its management
    Stanley C Jordan
    Transplant Immunology Laboratory, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90048, USA
    Clin J Am Soc Nephrol 1:421-32. 2006
    ..Despite the great interest in the problem of allosensitization, with one notable exception, there is a major deficiency in controlled clinical trials, the conduct of which should be a focus for the near future...
  15. doi request reprint Therapeutic strategies in management of the highly HLA-sensitized and ABO-incompatible transplant recipients
    Stanley C Jordan
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, Calif, USA
    Contrib Nephrol 162:13-26. 2009
    ....
  16. ncbi request reprint Utility of intravenous immune globulin in kidney transplantation: efficacy, safety, and cost implications
    Stanley Jordan
    Department of Pediatric Nephrology and Transplant Immunology, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Transplant 3:653-64. 2003
    ..In addition, the use of IVIG in solid organ transplant recipients will be reviewed. The adverse events, safety considerations, and economic impact of IVIG protocols for patients awaiting solid organ transplantation will be discussed...
  17. ncbi request reprint Expression of gamma-IFN mRNA in bronchoalveolar lavage fluid correlates with early acute allograft rejection in lung transplant recipients
    A Moudgil
    Department of Pediatrics, Steven Spielberg Pediatric Research Center, Los Angeles, CA 90048, USA
    Clin Transplant 13:201-7. 1999
    ..Absence of elevated IgG2/IgG1 ratio, and presence of IL-10 in BAL during AR suggests that Th-1 cytokines may not be the sole mediator of rejection in LT recipients...
  18. ncbi request reprint Effect of induction therapy protocols on transplant outcomes in crossmatch positive renal allograft recipients desensitized with IVIG
    A A Vo
    Comprehensive Transplant Center, Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Transplant 6:2384-90. 2006
    ..There was no increased risk of viral infections or malignancies with either agent. Neither agent was effective in reducing the incidence of AMR...
  19. ncbi request reprint Prolongation of allograft survival with viral IL-10 transfection in a highly histoincompatible model of rat heart allograft rejection
    Z Zuo
    Department of Pediatrics, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles, CA 90048, USA
    Transplantation 71:686-91. 2001
    ..2) Subtherapeutic doses of CsA do not prolong allograft survival, but act synergistically with vIL-10 to significantly prolong graft survival beyond that achieved with either agent alone...
  20. doi request reprint Mycophenolic acid and intravenous immunoglobulin exert an additive effect on cell proliferation and apoptosis in the mixed lymphocyte reaction
    Kavita G Sharma
    Transplant Immunology Laboratory, Comprehensive Transplant Center, Cedars Sinai Medical Center UCLA School of Medicine, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Transpl Immunol 23:117-20. 2010
    ..Mycophenolate mofetil inhibits immune cell proliferation and is an effective immunsuppressive agent. Here, we examined the possible synergistic effects of combined MMF and IVIG on cell proliferation and apoptosis induction in the MLR...
  21. ncbi request reprint Analysis of subcutaneous (SQ) alemtuzumab induction therapy in highly sensitized patients desensitized with IVIG and rituximab
    A A Vo
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Transplant 8:144-9. 2008
    ..Although uncontrolled, these observations suggest that induction therapy with Alemtuzumab appears feasible and indeed promising, but awaits more definitive study...
  22. ncbi request reprint Antithrombin III inhibits lymphocyte proliferation, immunoglobulin production and mRNA expression of lymphocyte growth factors (IL-2, gamma-IFN and IL-4) in vitro
    X J Zuo
    Department of Pediatrics, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles, CA 90048, USA
    Transpl Immunol 9:1-6. 2001
    ....
  23. ncbi request reprint Lung allograft dysfunction correlates with gamma-interferon gene expression in bronchoalveolar lavage
    D J Ross
    Division of Pulmonary and Critical Care Medicine, Cedars Sinai Medical Center Lung and Heart Lung Transplant Program, Los Angeles, California, USA
    J Heart Lung Transplant 18:627-36. 1999
    ..Here we correlate the "Th1/Th2 paradigm" in clinical lung transplantation with histologic findings and assess the effect on serial spirometric function...
  24. ncbi request reprint Posttransplant therapy using high-dose human immunoglobulin (intravenous gammaglobulin) to control acute humoral rejection in renal and cardiac allograft recipients and potential mechanism of action
    S C Jordan
    Steven Spielberg Pediatric Research Center and Department of Pediatrics, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Transplantation 66:800-5. 1998
    ..v.IG infusions, and subsequent transplantation can be accomplished successfully with a crossmatch-negative, histoincompatible organ...
  25. ncbi request reprint Successful use of oral ganciclovir for the treatment of intrauterine cytomegalovirus infection in a renal allograft recipient
    D P Puliyanda
    Center for Kidney Diseases and Transplantation, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    Transpl Infect Dis 7:71-4. 2005
    ..This is the first reported case to our knowledge of successful use of maternal ganciclovir to treat intrauterine CMV infection in a pregnant renal transplant recipient...
  26. ncbi request reprint Nephronophthisis associated with Ellis-van Creveld syndrome
    A Moudgil
    Ahmanson Department of Pediatrics, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Pediatr Nephrol 12:20-2. 1998
    ..The association of nephronophthisis in a patient with EvC syndrome has not been reported previously. This association further supports the hypothesis that ATD and EvC syndromes are related and represent a spectrum of disorders...
  27. ncbi request reprint Parvovirus B19 infection-related complications in renal transplant recipients: treatment with intravenous immunoglobulin
    A Moudgil
    Department of Pediatrics, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Transplantation 64:1847-50. 1997
    ..Chronic red cell aplasia can develop in immunocompromised patients including transplant recipients infected with parvovirus B19 (PV B19). Renal involvement with PV B19 infection is not well-recognized...
  28. ncbi request reprint Renal transplantation in infants and children
    A Moudgil
    Department of Pediatrics, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Indian J Pediatr 66:263-75. 1999
    ..Socio-economic factors should be evaluated before offering renal transplantation to children in developing countries...
  29. ncbi request reprint Cyclosporine microemulsion- and mycophenolate mofetil-related lymphoid aggregates are not associated with acute rejection
    C C Nast
    Department of Pathology, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Transplantation 72:251-6. 2001
    ..These lymphocytes may play a role in long-term allograft acceptance...
  30. ncbi request reprint Association of parvovirus B19 infection with idiopathic collapsing glomerulopathy
    A Moudgil
    Department of Pediatrics, Division of Transplant Immunology, Steven Spielberg Pediatric Research Center, UCLA School of Medicine, Los Angeles, California, USA
    Kidney Int 59:2126-33. 2001
    ..We previously reported a renal transplant recipient with de novo CG and red cell aplasia in association with persistent parvovirus B19 (PVB19) infection. This prompted us to look for an association between PVB19 infection and CG...
  31. ncbi request reprint The onset of rapidly progressive neurologic deterioration after a brief gastrointestinal illness in a renal allograft recipient
    I Hristea
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, California, USA
    Transpl Infect Dis 9:142-7. 2007
    ..We further review the epidemiology, microbiology, clinical presentation, and therapeutic options for listerial brain abscess...
  32. ncbi request reprint Cyclosporine-sparing effects of daclizumab in renal allograft recipients
    Gordon R Ingle
    Department of Pharmacy, St Vincent Medical Center, Los Angeles, CA 90057, USA
    Am J Health Syst Pharm 62:391-6. 2005
    ..The safety and efficacy of reduced-dose cyclosporine in renal transplantation were studied...
  33. ncbi request reprint Treatment of parvovirus B-19 (PV B-19) infection allows for successful kidney transplantation without disease recurrence
    Noha R Barsoum
    Cedars Sinai Medical Center, UCLA School of Medicine, L A, CA 90048, USA
    Am J Transplant 2:425-8. 2002
    ..Careful surveillance post transplantation is necessary to identify disease recurrence so that early treatment can be initiated...
  34. ncbi request reprint Immunomodulatory actions of intravenous immunoglobulin (IVIG): potential applications in solid organ transplant recipients
    S C Jordan
    Steven Spielberg Pediatric Research Center and Department of Pediatrics, Cedars Sinai Medical Center, and UCLA School of Medicine, Los Angeles, California 90048, USA
    Pediatr Transplant 2:92-105. 1998
    ..We will also discuss other potential anti-inflammatory and immunoregulatory mechanisms induced by IVIG treatment and how these may be applied to improve transplantability and outcomes in human transplantation...
  35. ncbi request reprint Analysis of the United Network for Organ Sharing database comparing renal allografts and patient survival in combined liver-kidney transplantation with the contralateral allografts in kidney alone or kidney-pancreas transplantation
    Tse Ling Fong
    USC Center for Liver Disease, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    Transplantation 76:348-53. 2003
    ....
  36. ncbi request reprint 14th International HLA and Immunogenetics Workshop: report on understanding antibodies in transplantation
    A A Zachary
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2222, USA
    Tissue Antigens 69:160-73. 2007
    ..This report is an integration of the presentations of those scientists...
  37. doi request reprint Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy
    Nancy L Reinsmoen
    HLA Laboratory, Cedars Sinai Medical Center, 8723 Alden Drive, SSB 197, Los Angeles, CA 90048, USA
    Transplantation 86:820-5. 2008
    ....
  38. doi request reprint Rituximab and intravenous immune globulin for desensitization during renal transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles 90048, USA
    N Engl J Med 359:242-51. 2008
    ..This exploratory, open-label, phase 1-2, single-center study examined whether intravenous immune globulin plus rituximab could reduce anti-HLA antibody levels and improve transplantation rates...
  39. doi request reprint Cellular allo reactivity against paternal HLA antigens in normal multiparous females as detected by intracellular cytokine flow cytometry remains elevated over years despite diminution of anti-HLA antibody levels
    Mieko Toyoda
    Transplant Immunology Laboratory, Comprehensive Transplant Center, Cedars Sinai Medical Center UCLA School of Medicine, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Transpl Immunol 23:133-40. 2010
    ..Here, we investigate allo-sensitization that results from paternal HLA (pHLA) Ag exposure in normal multiparous females and assess the utility of the CFC assay in detecting allo-Ag-specific immune cell activity...
  40. doi request reprint Therapeutic plasma exchange for desensitization prior to transplantation in ABO-incompatible renal allografts
    Praveen Sivakumaran
    Division of Transfusion Medicine, Pathology and Lab Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Clin Apher 24:155-60. 2009
    ....
  41. pmc Acute hemolysis after high-dose intravenous immunoglobulin therapy in highly HLA sensitized patients
    Joseph Kahwaji
    Comprehensive Transplant Center, Cedars Sinai Medical Center, West Los Angeles, CA 90048, USA
    Clin J Am Soc Nephrol 4:1993-7. 2009
    ..Here, we report our experience with IVIG-induced hemolytic anemia (IH) in ESRD patients receiving IVIG for desensitization or treatment of AMR...
  42. doi request reprint Intracellular IFNgamma production in CD3 negative cells exposed to allo-antigens is an indicator of prior sensitization
    Mieko Toyoda
    Transplant Immunology Laboratory, Comprehensive Transplant Center, Cedars Sinai Medical Center UCLA School of Medicine, 8700 Beverly Blvd, SSB111, Los Angeles, CA 90048, USA
    Transpl Immunol 22:121-7. 2010
    ....
  43. doi request reprint ABO blood group incompatibility: a diminishing barrier to successful kidney transplantation?
    Joseph Kahwaji
    Comprehensive Transplant Center, Transplant Immunotherapy Program, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Expert Rev Clin Immunol 6:893-900. 2010
    ..In this article, we describe the important contributions immunomodulatory drugs and antibody reduction therapies have made in achieving excellent outcomes in what was once an impenetrable barrier to transplantation...
  44. doi request reprint Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Transplantation 89:1095-102. 2010
    ....
  45. doi request reprint Anti-CD20 antibody suppresses anti-HLA antibody formation in a HLA-A2 transgenic mouse model of sensitization
    Gordon D Wu
    Comprehensive Transplant Center at Cedars Sinai Medical Center, Los Angeles, CA 90048, United States
    Transpl Immunol 19:178-86. 2008
    ..B cell depletion by anti-CD20 antibody is used in desensitization protocols and for treatment of antibody-mediated rejection (AMR). However, little is known about the efficacy and the mechanism(s) of action...
  46. doi request reprint Clinical significance of peripheral blood Epstein-Barr viral load monitoring using polymerase chain reaction in renal transplant recipients
    Mieko Toyoda
    Transplant Immunology Laboratory, Ahmanson Pediatric Center, Steven Spielberg Pediatric Research Laboratories, Cedars Sinai Medical Center UCLA School of Medicine, Los Angeles, CA 90048, USA
    Pediatr Transplant 12:778-84. 2008
    ..EBV-PCR monitoring in high-risk renal transplant recipients, especially in children, may allow early diagnosis and intervention, and therefore may help in preventing EBV-associated PTLD...
  47. ncbi request reprint Posttransplantation lymphoproliferative disorder presenting as a unilateral leg mass 10 years after kidney transplantation
    Suphamai Bunnapradist
    Center for Kidney Transplantation, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Transplantation 74:1648-51. 2002
    ..He is currently 2 years posttreatment, with a serum creatinine of 0.8 mg/dL, on no immunosuppression...
  48. ncbi request reprint Pooled human gammaglobulin modulates surface molecule expression and induces apoptosis in human B cells
    Mieko Toyoda
    Transplant Immunology Laboratory, Ahmanson Pediatric Center, Steven Spielberg Pediatric Research Laboratories, Cedars Sinai Medical Center UCLA School of Medicine, Los Angeles, CA, USA
    Am J Transplant 3:156-66. 2003
    ..This likely represents the primary mechanism responsible for IVIG suppression of the MLR, and may account for many of the observed beneficial effects of IVIG seen in the treatment of human autoimmune and alloimmune disorders...
  49. ncbi request reprint Dual kidneys from marginal adult donors as a source for cadaveric renal transplantation in the United States
    Suphamai Bunnapradist
    Center for Kidney and Kidney Pancreas Transplantation, Burns Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Soc Nephrol 14:1031-6. 2003
    ..When compared with SKT with donors over 55 yr of age, DKT resulted in similar graft outcomes. These otherwise discarded kidneys should be cautiously considered as a source of marginal donors...
  50. ncbi request reprint Fabry disease in a renal allograft
    Dechu P Puliyanda
    Center for Kidney Diseases, Department of Renal Pathology, Division of Medical Genetics, UCLA School of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Transplant 3:1030-2. 2003
    ..Two years post-transplant the patient continues to have non-nephrotic range proteinuria with normal serum creatinine...
  51. ncbi request reprint Immunomodulatory effects of combination of pooled human gammaglobulin and rapamycin on cell proliferation and apoptosis in the mixed lymphocyte reaction
    Mieko Toyoda
    Transplant Immunology Laboratory, Ahmanson Pediatric Center, Steven Spielberg Pediatric Research Laboratories, Cedars Sinai Medical Center UCLA School of Medicine, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Transplantation 78:1134-8. 2004
    ..Here we examined the possible synergistic effects of IVIG and RAPA on cell proliferation and apoptosis induction in the MLR...
  52. ncbi request reprint Co-infection of polyomavirus-BK and cytomegalovirus in renal transplant recipients
    Mieko Toyoda
    Transplant Immunology Laboratory, Ahmanson Pediatric Center, Steven Spielberg Pediatric Research Laboratories, Cedars Sinai Medical Center University of California, Los Angeles, 90048, USA
    Transplantation 80:198-205. 2005
    ..Polyomavirus-BK (BK) is a significant cause of allograft dysfunction in renal transplant recipients. Cytomegalovirus (CMV) and BK infection are thought to be possible risk factors for one another, but no supporting data are yet available...
  53. doi request reprint Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients
    Nancy L Reinsmoen
    Cedars Sinai Medical Center, HLA Laboratory, Comprehensive Transplant Center, Los Angeles, CA 90048, USA
    Transplantation 90:1473-7. 2010
    ....
  54. ncbi request reprint Safety and adverse events profiles of intravenous gammaglobulin products used for immunomodulation: a single-center experience
    Ashley A Vo
    Comprehensive Transplant Center, Cedars Sinai Medical Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90048, USA
    Clin J Am Soc Nephrol 1:844-52. 2006
    ..Gamimune-N 10% and other IVIg products were frequently associated with headaches. Administration of IVIg to patients who are on hemodialysis seems to be safe and effective...
  55. doi request reprint Immunologic parameters and viral infections in patients desensitized with intravenous immunoglobulin and rituximab
    Shili Ge
    Transplant Immunology Laboratory, Comprehensive Transplant Center, Cedars Sinai Medical Center UCLA School of Medicine, 8700 Beverly Blvd, SSB111, Los Angeles, CA 90048, USA
    Transpl Immunol 24:142-8. 2011
    ..Although post-transplant induction therapy is associated with a transient depletion of viral-specific CD8+ memory cells, it does not increase risks for viral infections...
  56. ncbi request reprint Rapid remission of steroid and mycophenolate mofetil (mmf)-resistant minimal change nephrotic syndrome after rituximab therapy
    Tom Yang
    Department of Medicine, Division of Nephrology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Nephrol Dial Transplant 23:377-80. 2008
  57. doi request reprint IFN╬│ production by NK cells from HLA-sensitized patients after in vitro exposure to allo-antigens
    M Toyoda
    Transplant Immunology Laboratory, Cedars Sinai Medical Center UCLA School of Medicine, 8723 Alden Dr, Steven Spielberg Bldg, Los Angeles, CA 90048, USA
    Transpl Immunol 26:107-12. 2012
    ....
  58. ncbi request reprint Nephrocalcinosis and renal cysts associated with apparent mineralocorticoid excess syndrome
    A Moudgil
    Ahmanson Department of Pediatrics, Cedars Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, USA
    Pediatr Nephrol 15:60-2. 2000
    ..The development of nephrocalcinosis and renal cysts may be associated with chronic long-standing hypokalemia. An early diagnosis and treatment of AME syndrome could help to prevent these sequelae, and to preserve renal function...
  59. doi request reprint Use of ventricular assist device as bridge to simultaneous heart and kidney transplantation in patients with cardiac and renal failure
    R Yanagida
    Division of Cardiothoracic Surgery, Cedars Sinai Heart Institute, Los Angeles, California Departments of Medicine and Pediatrics, and Multiorgan Transplant Program, Cedars Sinai Medical Center, Los Angeles, California
    Transplant Proc 45:2378-83. 2013
    ..We present our experience with 6 patients who had combined heart and kidney transplantation (HKT) after VAD implantation for advanced cardiac and renal failure...
  60. ncbi request reprint Transient cold preservation alone stimulates tumor necrosis factor-alpha gene expression in a model of rat syngeneic lung transplantation
    Y Okada
    Department of Cardiothoracic Surgery, Pediatrics and Pathology, The Cedars Sinai Medical Center Burns, Los Angeles, California, USA
    Transplant Proc 34:1111-3. 2002
  61. ncbi request reprint Impact of hepatitis B core antibody status on outcomes of cadaveric renal transplantation: analysis of United network of organ sharing database between 1994 and 1999
    Tse Ling Fong
    Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue HMR 101, Los Angeles CA 90033, USA
    Transplantation 73:85-9. 2002
    ..To address these issues, an analysis was performed using the United Network of Organ Sharing cadaveric kidney transplant database between 1994 to 1999...
  62. ncbi request reprint Management of the highly HLA- sensitized patient. A novel role for intravenous gammaglobulin
    Stanley C Jordan
    Am J Transplant 2:691-2. 2002
  63. ncbi request reprint Consensus opinion from the antibody working group on the diagnosis, reporting, and risk assessment for antibody-mediated rejection and desensitization protocols
    Robert A Montgomery
    Department of Surgery, Division of Transplantation, Johns Hopkins University School of Medicine, Ross 765 720 Rutland Avenue, Baltimore, MD 21205, USA
    Transplantation 78:181-5. 2004
    ..The Antibody Working Group was assembled in an attempt to provide guidelines for the standardization of nomenclature, diagnostic criteria, reporting, antibody profiling, and risk assessment...
  64. ncbi request reprint Mycophenolate mofetil and prednisolone therapy in children with steroid-dependent nephrotic syndrome
    Arvind Bagga
    Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Am J Kidney Dis 42:1114-20. 2003
    ..We prospectively examined the efficacy of long-term therapy with mycophenolate mofetil (MMF) as a steroid-sparing agent in this group...
  65. ncbi request reprint Atopy, serum IgE, and interleukin-13 in steroid-responsive nephrotic syndrome
    Wai Cheung
    Department of Pediatrics, National University of Singapore, 5 Lower Kent Ridge Crescent, 119074 Singapore
    Pediatr Nephrol 19:627-32. 2004
    ..This probably reflects some common immune activation following various stimuli, rather than a direct association with atopy...
  66. ncbi request reprint Treatment with mycophenolate mofetil and prednisolone for steroid-dependent nephrotic syndrome
    Kamran Afzal
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India
    Pediatr Nephrol 22:2059-65. 2007
    ..This data confirms the efficacy and safety of treatment with MMF and tapering doses of alternate-day prednisolone in patients with SDNS and supports its use for longer than 12 months...
  67. ncbi request reprint Adenovirus mediated IL-10 gene transfer to the airway of the rat lung for prevention of lung allograft rejection
    Yoshinori Okada
    Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4 1 Seiryomachi, Aoba ku, Sendai 980 8575, Japan
    Transpl Immunol 16:95-8. 2006
    ..We examined the feasibility of transferring the viral interleukin-10 (vIL-10) gene into rat lungs by intra-bronchial instillation and the subsequent effects of delivered vIL-10 on acute lung AR...