Talin Haritunians

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. ncbi Variants in ZNF365 isoform D are associated with Crohn's disease
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Gut 60:1060-7. 2011
  2. ncbi Genetic predictors of medically refractory ulcerative colitis
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 16:1830-40. 2010
  3. ncbi Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies
    Yelena Bykhovskaya
    Regenerative Medicine Institute, Ophthalmology Research, Department of Surgery, Division of Surgical Research, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Invest Ophthalmol Vis Sci 53:4152-7. 2012
  4. ncbi Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Hum Mol Genet 19:3468-76. 2010
  5. ncbi Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease
    Marla C Dubinsky
    Department of Pediatrics and Medicine, Inflammatory Bowel Disease Program, Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Inflamm Bowel Dis 16:1357-66. 2010
  6. ncbi Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
    Dermot P B McGovern
    Medical Genetics Institute and Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 15:883-9. 2009
  7. ncbi Genome-wide association identifies multiple ulcerative colitis susceptibility loci
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Nat Genet 42:332-7. 2010
  8. ncbi Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells
    Talin Haritunians
    Division of Hematology Oncology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Leuk Res 32:1366-73. 2008
  9. ncbi A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries
    Xiaohui Li
    Cornea Genetic Eye Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Hum Mol Genet 21:421-9. 2012
  10. ncbi Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts
    Kent D Taylor
    Medical Genetics Institute, and Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Genet Med 6:481-6. 2004

Detail Information

Publications12

  1. ncbi Variants in ZNF365 isoform D are associated with Crohn's disease
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Gut 60:1060-7. 2011
    ..Genome-wide association studies have identified multiple Crohn's disease (CD) susceptibility loci, including association with non-coding intergenic single-nucleotide polymorphisms (SNPs) at 10q21...
  2. ncbi Genetic predictors of medically refractory ulcerative colitis
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 16:1830-40. 2010
    ..The aim of this study was to use a genome-wide association study (GWAS) in a well-characterized cohort of UC patients to identify genetic variation that contributes to MR-UC...
  3. ncbi Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies
    Yelena Bykhovskaya
    Regenerative Medicine Institute, Ophthalmology Research, Department of Surgery, Division of Surgical Research, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Invest Ophthalmol Vis Sci 53:4152-7. 2012
    ..To determine whether LOX is a genetic determinant of the pathogenesis of keratoconus, we analyzed association results of LOX polymorphisms in two independent case-control samples and in keratoconus families...
  4. ncbi Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Hum Mol Genet 19:3468-76. 2010
    ..001). These findings strongly implicate this locus in CD susceptibility and highlight the role of the mucus layer in the development of CD...
  5. ncbi Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease
    Marla C Dubinsky
    Department of Pediatrics and Medicine, Inflammatory Bowel Disease Program, Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Inflamm Bowel Dis 16:1357-66. 2010
    ....
  6. ncbi Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
    Dermot P B McGovern
    Medical Genetics Institute and Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 15:883-9. 2009
    ..Genetic variants in the IL23R and IL12B have been associated with CD susceptibility. We investigated 10 genes within the IL23/IL17 pathway in a case-control study of 763 CD cases and 254 healthy controls...
  7. ncbi Genome-wide association identifies multiple ulcerative colitis susceptibility loci
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Nat Genet 42:332-7. 2010
    ..These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis...
  8. ncbi Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells
    Talin Haritunians
    Division of Hematology Oncology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Leuk Res 32:1366-73. 2008
    ..These encouraging results suggest the appropriateness of clinical trials of cucurbitacins for the treatment of hematopoietic malignancies...
  9. ncbi A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries
    Xiaohui Li
    Cornea Genetic Eye Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Hum Mol Genet 21:421-9. 2012
    ..6 × 10(-7) (unadjusted P= 1.2 × 10(-9)). These findings suggest SNP rs4954218, located near the RAB3GAP1 gene, previously reported to be associated with corneal malformation, is a potential susceptibility locus for keratoconus...
  10. ncbi Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts
    Kent D Taylor
    Medical Genetics Institute, and Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Genet Med 6:481-6. 2004
    ..Our aim was to test whether polymorphisms in the lipoprotein lipase (LPL) gene were associated with the progression of atherosclerosis in grafts examined in the Post-Coronary Artery Bypass Graft Trial (Post-CABG Trial)...
  11. ncbi Novel acyl sulfonamide LY573636-sodium: effect on hematopoietic malignant cells
    Talin Haritunians
    Division of Hematology Oncology, Cedars Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA 90048, USA
    Oncol Rep 20:1237-42. 2008
    ..LY573636, as shown before in solid tumors, is effective in hematopoietic cell lines as well. These data suggest the use of LY573636 alone or in combination with conventional chemotherapeutic regimens in hematopoietic malignancies...
  12. ncbi Novel Gemini vitamin D(3) analogs have potent antitumor activity
    Tsuyako Saito
    Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
    J Steroid Biochem Mol Biol 112:151-6. 2008
    ..05) more apoptosis than 1,25(OH)(2)D(3). In summary, these analogs have a unique structure resulting in extremely potent inhibition of clonal proliferation of various types of cancer cells, especially HL-60 cells...