Guido Germano

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. ncbi Attenuation correction in cardiac SPECT: the boy who cried wolf?
    Guido Germano
    UCLA School of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Cardiol 14:25-35. 2007
  2. ncbi Quantitative single-photon emission computed tomography imaging
    Guido Germano
    Artificial Intelligence in Medicine Program, Cedars Sinai Medical Center, 8700 Beverly Boulevard, A047N, Los Angeles, CA 90048, USA
    Curr Cardiol Rep 7:136-42. 2005
  3. ncbi Quantitation in gated perfusion SPECT imaging: the Cedars-Sinai approach
    Guido Germano
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 14:433-54. 2007
  4. ncbi Diagnostic accuracy of gated Tc-99m sestamibi stress myocardial perfusion SPECT with combined supine and prone acquisitions to detect coronary artery disease in obese and nonobese patients
    Daniel S Berman
    Department of Imaging, Division of Nuclear Medicine, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 13:191-201. 2006
  5. ncbi Predicting therapeutic benefit from myocardial revascularization procedures: are measurements of both resting left ventricular ejection fraction and stress-induced myocardial ischemia necessary?
    Rory Hachamovitch
    Cardiovascular Division, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif, USA
    J Nucl Cardiol 13:768-78. 2006
  6. ncbi Are shades of gray prognostically useful in reporting myocardial perfusion single-photon emission computed tomography?
    Aiden Abidov
    Department of Imaging and the Department of Medicine, Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circ Cardiovasc Imaging 2:290-8. 2009
  7. ncbi Vulnerable plaque features on coronary CT angiography as markers of inducible regional myocardial hypoperfusion from severe coronary artery stenoses
    Haim Shmilovich
    Heart Institute and the Departments of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Atherosclerosis 219:588-95. 2011
  8. ncbi Assessment of diastolic function using 16-frame 99mTc-sestamibi gated myocardial perfusion SPECT: normal values
    Cigdem Akincioglu
    Department of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 46:1102-8. 2005
  9. ncbi Prognostic impact of hemodynamic response to adenosine in patients older than age 55 years undergoing vasodilator stress myocardial perfusion study
    Aiden Abidov
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Blvd, Taper Building, Room 1258, Los Angeles, CA 90048, USA
    Circulation 107:2894-9. 2003
  10. ncbi Comparison of the extent and severity of myocardial perfusion defects measured by CT coronary angiography and SPECT myocardial perfusion imaging
    Balaji K Tamarappoo
    Department of Imaging, Division of Nuclear Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    JACC Cardiovasc Imaging 3:1010-9. 2010

Collaborators

Detail Information

Publications79

  1. ncbi Attenuation correction in cardiac SPECT: the boy who cried wolf?
    Guido Germano
    UCLA School of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Cardiol 14:25-35. 2007
  2. ncbi Quantitative single-photon emission computed tomography imaging
    Guido Germano
    Artificial Intelligence in Medicine Program, Cedars Sinai Medical Center, 8700 Beverly Boulevard, A047N, Los Angeles, CA 90048, USA
    Curr Cardiol Rep 7:136-42. 2005
    ..This article describes the many quantitative cardiac SPECT measurements available today, defining them in terms of validation, practical use, and limitations...
  3. ncbi Quantitation in gated perfusion SPECT imaging: the Cedars-Sinai approach
    Guido Germano
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 14:433-54. 2007
    ....
  4. ncbi Diagnostic accuracy of gated Tc-99m sestamibi stress myocardial perfusion SPECT with combined supine and prone acquisitions to detect coronary artery disease in obese and nonobese patients
    Daniel S Berman
    Department of Imaging, Division of Nuclear Medicine, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 13:191-201. 2006
    ..The diagnostic value of gated myocardial perfusion single-photon emission computed tomography (MPS) with combined supine and prone acquisitions to detect coronary artery disease (CAD) in obese and nonobese patients has not been defined...
  5. ncbi Predicting therapeutic benefit from myocardial revascularization procedures: are measurements of both resting left ventricular ejection fraction and stress-induced myocardial ischemia necessary?
    Rory Hachamovitch
    Cardiovascular Division, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif, USA
    J Nucl Cardiol 13:768-78. 2006
    ..We hypothesized that ejection fraction (EF) best predicts cardiovascular death but only measures of ischemia predict relative survival benefit from revascularization compared with medical therapy...
  6. ncbi Are shades of gray prognostically useful in reporting myocardial perfusion single-photon emission computed tomography?
    Aiden Abidov
    Department of Imaging and the Department of Medicine, Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circ Cardiovasc Imaging 2:290-8. 2009
    ..The prognostic value of expressing levels of certainty compared with a dichotomous normal/abnormal classification or categories for summed stress scores is unclear...
  7. ncbi Vulnerable plaque features on coronary CT angiography as markers of inducible regional myocardial hypoperfusion from severe coronary artery stenoses
    Haim Shmilovich
    Heart Institute and the Departments of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Atherosclerosis 219:588-95. 2011
    ....
  8. ncbi Assessment of diastolic function using 16-frame 99mTc-sestamibi gated myocardial perfusion SPECT: normal values
    Cigdem Akincioglu
    Department of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 46:1102-8. 2005
    ..However, due to the dependency of PFR on SFx parameters, sex, HR, and age, TTPF appears to be a stable and more useful parameter with this approach. The clinical usefulness of these findings requires further study...
  9. ncbi Prognostic impact of hemodynamic response to adenosine in patients older than age 55 years undergoing vasodilator stress myocardial perfusion study
    Aiden Abidov
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Blvd, Taper Building, Room 1258, Los Angeles, CA 90048, USA
    Circulation 107:2894-9. 2003
    ..The prognostic importance of various hemodynamic responses to adenosine infusion in patients undergoing adenosine stress myocardial perfusion stress (MPS) has not been defined...
  10. ncbi Comparison of the extent and severity of myocardial perfusion defects measured by CT coronary angiography and SPECT myocardial perfusion imaging
    Balaji K Tamarappoo
    Department of Imaging, Division of Nuclear Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    JACC Cardiovasc Imaging 3:1010-9. 2010
    ....
  11. ncbi Automated 3-dimensional quantification of noncalcified and calcified coronary plaque from coronary CT angiography
    Damini Dey
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A238, Los Angeles, CA 90048, USA
    J Cardiovasc Comput Tomogr 3:372-82. 2009
    ..We aimed to develop an automated algorithm (APQ) for accurate volumetric quantification of non-calcified (NCP) and calcified plaque (CP) from coronary CT angiography (CCTA)...
  12. ncbi Enhanced definition PET for cardiac imaging
    Ludovic Le Meunier
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, Taper Bldg, A238, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    J Nucl Cardiol 17:414-26. 2010
    ..We aimed to determine in phantom and cardiac clinical studies the impact of a new high-resolution PET image reconstruction...
  13. ncbi Integration of automatically measured transient ischemic dilation ratio into interpretation of adenosine stress myocardial perfusion SPECT for detection of severe and extensive CAD
    Aiden Abidov
    Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 45:1999-2007. 2004
    ..Integration of abnormal TID ratio into the dual-isotope MPS image interpretation algorithm improves the identification of severe and extensive CAD in adenosine MPS...
  14. ncbi Combined quantitative supine-prone myocardial perfusion SPECT improves detection of coronary artery disease and normalcy rates in women
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 14:44-52. 2007
    ....
  15. ncbi Prognostic value of poststress left ventricular volume and ejection fraction by gated myocardial perfusion SPECT in women and men: gender-related differences in normal limits and outcomes
    Tali Sharir
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif. 90048, USA
    J Nucl Cardiol 13:495-506. 2006
    ..After separate criteria for abnormal EF and ESV index in women are used, the combination of severe ischemia and abnormal EF or ESV index identifies women at very high risk of cardiac events...
  16. ncbi Prognostic value of myocardial perfusion SPECT versus exercise electrocardiography in patients with ST-segment depression on resting electrocardiography
    Andrea De Lorenzo
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Cardiol 12:655-61. 2005
    ....
  17. ncbi Comparative use of radionuclide stress testing, coronary artery calcium scanning, and noninvasive coronary angiography for diagnostic and prognostic cardiac assessment
    Daniel S Berman
    Department of Imaging and Medicine, Cedars Sinai Medical Center, CSMC Burns and Allen Research Institute, Los Angeles, CA 90048, USA
    Semin Nucl Med 37:2-16. 2007
    ....
  18. ncbi Left ventricular shape index assessed by gated stress myocardial perfusion SPECT: initial description of a new variable
    Aiden Abidov
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 13:652-9. 2006
    ..CONCLUSION: LVSI is a promising new 3D variable derived automatically from gated MPS providing highly repeatable ventricular shape assessment. Preliminary findings suggest that LVSI might have clinical implications in patients with CHF...
  19. ncbi Threshold, incidence, and predictors of prognostically high-risk silent ischemia in asymptomatic patients without prior diagnosis of coronary artery disease
    Michael J Zellweger
    Department of Imaging Division of Nuclear Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    J Nucl Cardiol 16:193-200. 2009
    ..Little is known about incidence, threshold, and predictors of prognostically relevant silent ischemia (SI). The aim was to study these three aspects of silent coronary artery disease (CAD)...
  20. ncbi Aortic size assessment by noncontrast cardiac computed tomography: normal limits by age, gender, and body surface area
    Arik Wolak
    Departments of Imaging, CSMC Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California at Los Angeles, USA
    JACC Cardiovasc Imaging 1:200-9. 2008
    ..To determine normal limits for ascending and descending thoracic aorta diameters in a large population of asymptomatic, low-risk adult subjects...
  21. ncbi Prognostic implications of atrial fibrillation in patients undergoing myocardial perfusion single-photon emission computed tomography
    Aiden Abidov
    Departments of Imaging (Division of Nuclear Medicine) and Medicine (Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 44:1062-70. 2004
    ..Whether patients with AF and mildly abnormal MPS constitute a group more deserving of early referral to cardiac catheterization is a question warranting further study...
  22. ncbi Automatic quantification of myocardial perfusion stress-rest change: a new measure of ischemia
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, A047 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    J Nucl Med 45:183-91. 2004
    ..Such an approach is not optimal because images are not compared directly with each other and a complex set of stress and rest normal limits is required...
  23. ncbi Quantitative assessment of myocardial perfusion abnormality on SPECT myocardial perfusion imaging is more reproducible than expert visual analysis
    Daniel S Berman
    Department of Imaging Division of Nuclear Medicine, Cedars Sinai Heart Institute, 8700 Beverly Boulevard, Room 1258, Los Angeles, CA 90048, USA
    J Nucl Cardiol 16:45-53. 2009
    ..Few studies have addressed whether quantitative SPECT MPI assessment would be more reproducible for this application...
  24. ncbi Prognostic value of automated vs visual analysis for adenosine stress myocardial perfusion SPECT in patients without prior coronary artery disease: a case-control study
    Yuan Xu
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, 8700 Beverly Blvd, Taper A047, Los Angeles, CA 90048, USA
    J Nucl Cardiol 18:1003-9; quiz 1010-4. 2011
    ....
  25. ncbi Prognostic implications of myocardial perfusion single-photon emission computed tomography in the elderly
    Rory Hachamovitch
    Department of Imaging, Division of Nuclear Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circulation 120:2197-206. 2009
    ..The goal of this study was to assess the clinical value of stress myocardial perfusion scintigraphy (MPS) in elderly patients (> or =75 years of age)...
  26. ncbi Comparison of myocardial perfusion 82Rb PET performed with CT- and transmission CT-based attenuation correction
    Piotr J Slomka
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Nucl Med 49:1992-8. 2008
    ..Our study aimed to compare the transmission CT (TCT)-based and CT-based AC for myocardial perfusion PET/CT images with a direct semiquantitative approach comparing differences in segmental count distribution...
  27. ncbi Quantification of 3D regional myocardial wall thickening from gated magnetic resonance images
    Mithun Prasad
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Magn Reson Imaging 31:317-27. 2010
    ..To develop 3D quantitative measures of regional myocardial wall motion and thickening using cardiac magnetic resonance imaging (MRI) and to validate them by comparison to standard visual scoring assessment...
  28. ncbi Underestimation of extent of ischemia by gated SPECT myocardial perfusion imaging in patients with left main coronary artery disease
    Daniel S Berman
    Department of Imaging Division of Nuclear Medicine, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 14:521-8. 2007
    ..There have been limited data regarding the value of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) for the detection of left main coronary artery disease (CAD)...
  29. ncbi Assessment of the relationship between stenosis severity and distribution of coronary artery stenoses on multislice computed tomographic angiography and myocardial ischemia detected by single photon emission computed tomography
    Balaji K Tamarappoo
    Department of Imaging Division of Nuclear Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Room 1258, Los Angeles, California 90048, USA
    J Nucl Cardiol 17:791-802. 2010
    ..We sought to evaluate the relationship between stenosis severity assessed by CCTA and ischemia on SPECT-MPI...
  30. ncbi Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT
    Aiden Abidov
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 42:1818-25. 2003
    ..Our findings also appear to apply to the broader population of "normal" MPS, which included patients with minimal perfusion defects...
  31. ncbi Combined supine and prone quantitative myocardial perfusion SPECT: method development and clinical validation in patients with no known coronary artery disease
    Hidetaka Nishina
    Department of Imaging and CSMC Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 47:51-8. 2006
    ..95%, P < 0.001). CONCLUSION: Combined supine-prone quantification significantly improves the area under the ROC curve and specificity of MPS in the identification of obstructive CAD compared with quantification of supine MPS alone...
  32. ncbi Impact of body mass index on cardiac mortality in patients with known or suspected coronary artery disease undergoing myocardial perfusion single-photon emission computed tomography
    Xingping Kang
    Department of Imaging, Division of Nuclear Medicine, and CSMC Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 47:1418-26. 2006
    ..In patients with known CAD undergoing MPS, obese and overweight patients were at lower risk of CD over three years than normal weight patients...
  33. ncbi Automated quantitative Rb-82 3D PET/CT myocardial perfusion imaging: normal limits and correlation with invasive coronary angiography
    Ryo Nakazato
    Departments of Imaging and Medicine, and Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 19:265-76. 2012
    ..We aimed to characterize normal limits and to determine the diagnostic accuracy for an automated quantification of 3D 82-Rubidium (Rb-82) PET/CT myocardial perfusion imaging (MPI)...
  34. ncbi Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans: what is the warranty period of a normal scan?
    Rory Hachamovitch
    Division of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
    J Am Coll Cardiol 41:1329-40. 2003
    ..The aim of this study was to determine the predictors of risk and the temporal characteristics of risk associated with normal myocardial perfusion single photon emission computed tomography (MPS)...
  35. ncbi Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: Noninvasive risk stratification and a conceptual framework for the selection of noninvasive imaging tests in patients with known or suspected coronary artery disease
    Daniel S Berman
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Burns and Allen Research Institute, Los Angeles, California 90048, USA
    J Nucl Med 47:1107-18. 2006
    ..We consider it likely that, with an increased emphasis on prevention and a concomitant aging of the population, many forms of noninvasive cardiac imaging will continue to grow, with nuclear cardiology continuing to grow...
  36. ncbi Automatic 3D registration of dynamic stress and rest (82)Rb and flurpiridaz F 18 myocardial perfusion PET data for patient motion detection and correction
    Jonghye Woo
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Med Phys 38:6313-26. 2011
    ..The patient motion correction was of primary interest and the effects of patient motion with the use of flurpiridaz F 18 and (82)Rb were demonstrated...
  37. ncbi Transient ischemic dilation for coronary artery disease in quantitative analysis of same-day sestamibi myocardial perfusion SPECT
    Yuan Xu
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Blvd, Taper A238, Los Angeles, CA 90048, USA
    J Nucl Cardiol 19:465-73. 2012
    ..However, TID has not been evaluated for 99mTc-sestamibi rest/stress protocols (Mibi-Mibi). We aimed to develop normal limits and evaluate diagnostic power of TID ratio for Mibi-Mibi scans...
  38. ncbi Geometric feature-based multimodal image registration of contrast-enhanced cardiac CT with gated myocardial perfusion SPECT
    Jonghye Woo
    Department of Imaging AIM program, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Med Phys 36:5467-79. 2009
    ..Fused anatomical and physiological data acquired sequentially on separate scanners can be coregistered to accurately diagnose CAD in specific coronary vessels...
  39. ncbi "Motion-frozen" display and quantification of myocardial perfusion
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 45:1128-34. 2004
    ..To improve the image quality and accuracy of gated MPS we propose to eliminate the influence of cardiac LV motion in the display and quantification by a novel "motion-frozen" (MF) technique...
  40. ncbi Improved quantification and normal limits for myocardial perfusion stress-rest change
    Mithun Prasad
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Nucl Med 51:204-9. 2010
    ..We aimed to improve the quantification of myocardial perfusion stress-rest changes in myocardial perfusion SPECT (MPS) studies for the optimal automatic detection of ischemia and coronary artery disease (CAD)...
  41. ncbi Motion frozen (18)F-FDG cardiac PET
    Ludovic Le Meunier
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Nucl Cardiol 18:259-66. 2011
    ..quot;Cardiac Motion Frozen" (CMF) processing eliminates the influence of cardiac motion in static summed images. We have evaluated the combined use of CMF- and PSF-based reconstruction for high-resolution cardiac PET...
  42. ncbi Nonlinear registration of serial coronary CT angiography (CCTA) for assessment of changes in atherosclerotic plaque
    Jonghye Woo
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Med Phys 37:885-96. 2010
    ..To this end, the authors aimed at developing a fully automatic nonlinear volume coregistration for longitudinal CCTA scan pairs...
  43. ncbi Automated quality control for segmentation of myocardial perfusion SPECT
    Yuan Xu
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Nucl Med 50:1418-26. 2009
    ..We have developed a technique to automatically detect these failures for both nongated and gated studies...
  44. ncbi Is there a referral bias against catheterization of patients with reduced left ventricular ejection fraction? Influence of ejection fraction and inducible ischemia on post-single-photon emission computed tomography management of patients without a history
    Rory Hachamovitch
    Cardiovascular Division, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Am Coll Cardiol 42:1286-94. 2003
    ....
  45. ncbi Prognostic validation of a 17-segment score derived from a 20-segment score for myocardial perfusion SPECT interpretation
    Daniel S Berman
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 11:414-23. 2004
    ..Methods to convert databases from previous 20- to new 17-segment data and criteria for abnormality for the 17-segment scores are needed...
  46. ncbi Automated quantification of myocardial perfusion SPECT using simplified normal limits
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 12:66-77. 2005
    ..To simplify development of normal limits for myocardial perfusion SPECT (MPS), we implemented a quantification scheme in which normal limits are derived without visual scoring of abnormal scans or optimization of regional thresholds...
  47. ncbi Prognostic significance of dyspnea in patients referred for cardiac stress testing
    Aiden Abidov
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
    N Engl J Med 353:1889-98. 2005
    ..Our results suggest that an assessment of dyspnea should be incorporated into the clinical evaluation of patients referred for cardiac stress testing...
  48. ncbi Combined quantitative analysis of attenuation corrected and non-corrected myocardial perfusion SPECT: Method development and clinical validation
    Yuan Xu
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Blvd, Taper A047, Los Angeles, CA 90048, USA
    J Nucl Cardiol 17:591-9. 2010
    ..We aimed to develop a combined quantitative analysis from AC and NC data to improve the accuracy of automated detection of CAD from AC-MPS...
  49. ncbi Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: assessment of patients with suspected coronary artery disease
    Daniel S Berman
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Burns and Allen Research Institute, Los Angeles, California 90048, USA
    J Nucl Med 47:74-82. 2006
    ..While CT and CMR are likely to grow considerably in diagnostic evaluation over the next several years, MPS and PET will continue to be very valuable techniques for this purpose...
  50. ncbi Simplified normal limits and automated quantitative assessment for attenuation-corrected myocardial perfusion SPECT
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 13:642-51. 2006
    ....
  51. ncbi Rapid assessment of left ventricular segmental wall motion, ejection fraction, and volumes with single breath-hold, multi-slice TrueFISP MR imaging
    David S Fieno
    Department of Imaging (Division of Cardiology, and CSMC Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Cardiovasc Magn Reson 8:435-44. 2006
    ..This approach may serve as a screening exam for assessment of WMA and, under select circumstances, may substitute for standard multi-breath-hold method in situations requiring rapid accurate assessments of LV function...
  52. ncbi Automatic detection and size quantification of infarcts by myocardial perfusion SPECT: clinical validation by delayed-enhancement MRI
    Piotr J Slomka
    Artificial Intelligence in Medicine Program, Departments of Imaging and Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    J Nucl Med 46:728-35. 2005
    ..We aimed to validate the accuracy of a new automated myocardial perfusion SPECT quantification based on normal limits for detection and sizing of infarcts, using delayed-enhancement MRI (DE-MRI) as a gold standard...
  53. ncbi Computer-aided non-contrast CT-based quantification of pericardial and thoracic fat and their associations with coronary calcium and Metabolic Syndrome
    Damini Dey
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 209:136-41. 2010
    ....
  54. ncbi Algorithm for radiation dose reduction with helical dual source coronary computed tomography angiography in clinical practice
    Ariel Gutstein
    Department of Imaging, Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Cardiovasc Comput Tomogr 2:311-22. 2008
    ..Strategies to reduce the radiation dose of coronary computed tomography angiography (CCTA), while maintaining diagnostic image quality, are imperative for cardiac CT...
  55. ncbi Dual-source coronary computed tomography angiography in patients with atrial fibrillation: initial experience
    Arik Wolak
    Departments of Imaging and Medicine, and CSMC Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California at Los Angeles, CA, USA
    J Cardiovasc Comput Tomogr 2:172-80. 2008
    ..The 83-millisecond temporal resolution of the dual-source CT (DSCT) may be sufficient to allow CCTA in patients with AF...
  56. ncbi Quantitation of infarct size in patients with chronic coronary artery disease using rest-redistribution Tl-201 myocardial perfusion SPECT: correlation with contrast-enhanced cardiac magnetic resonance
    David S Fieno
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 14:59-67. 2007
    ..We sought to determine whether rest or redistribution Tl-201 MPS provides an accurate determination of infarct size as defined by delayed contrast-enhanced cardiac magnetic resonance (CMR)...
  57. ncbi Patient motion correction for multiplanar, multi-breath-hold cardiac cine MR imaging
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, A047 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    J Magn Reson Imaging 25:965-73. 2007
    ..To correct for spatial misregistration of multi-breath-hold short-axis (SA), two-chamber (2CH), and four-chamber (4CH) cine cardiac MR (CMR) images caused by respiratory and patient motion...
  58. ncbi Applications and software techniques for integrated cardiac multimodality imaging
    Piotr J Slomka
    Department of Medicine, David Geffen School of Medicine at the UCLA, Los Angeles, CA, USA
    Expert Rev Cardiovasc Ther 6:27-41. 2008
    ..In this review, we present the latest approaches for integration of cardiac images from multiple modalities...
  59. ncbi Image quality and artifacts in coronary CT angiography with dual-source CT: initial clinical experience
    Damini Dey
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    J Cardiovasc Comput Tomogr 2:105-14. 2008
    ..We aimed to characterize artifacts observed in a routine clinical coronary CT angiography (CCTA) performed by a dual-source CT (DSCT) scanner (Definition; Siemens Medical Solutions)...
  60. ncbi Comparison of Fully Automated Computer Analysis and Visual Scoring for Detection of Coronary Artery Disease from Myocardial Perfusion SPECT in a Large Population
    Reza Arsanjani
    Departments of Imaging and Medicine and Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California
    J Nucl Med 54:221-8. 2013
    ....
  61. ncbi Adenosine myocardial perfusion single-photon emission computed tomography in women compared with men. Impact of diabetes mellitus on incremental prognostic value and effect on patient management
    Daniel S Berman
    Department of Imaging, Division of Nuclear Medicine, and CSMC Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California Los Angeles, School of Medicine, Los Angeles, California 90048, USA
    J Am Coll Cardiol 41:1125-33. 2003
    ..This study was designed to assess the incremental prognostic value of adenosine stress myocardial perfusion single-photon emission computed tomography (MPS) in women versus men, and to explore the prognostic impact of diabetes mellitus...
  62. ncbi Prognostic relevance of symptoms versus objective evidence of coronary artery disease in diabetic patients
    Michael J Zellweger
    Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA
    Eur Heart J 25:543-50. 2004
    ..The outcome was three times worse in diabetic patients with shortness of breath. MPS findings were strongly predictive of outcome and proved valuable for risk stratification...
  63. ncbi Quantitative diagnostic performance of myocardial perfusion SPECT with attenuation correction in women
    Arik Wolak
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 49:915-22. 2008
    ..We aimed to evaluate the performance of AC in women by using automated quantitative analysis of MPS to avoid any bias...
  64. ncbi Quantitative myocardial-perfusion SPECT: comparison of three state-of-the-art software packages
    Arik Wolak
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 15:27-34. 2008
    ..We aimed to compare the automation and diagnostic performance in the detection of coronary artery disease (CAD) of the 4DMSPECT (4DM), Emory Cardiac Toolbox (EMO), and QPS systems for automated quantification of myocardial perfusion...
  65. ncbi Motion-frozen myocardial perfusion SPECT improves detection of coronary artery disease in obese patients
    Yasuyuki Suzuki
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 49:1075-9. 2008
    ..In this study, we compared the diagnostic performance of the standard SPECT with motion-frozen (MF) myocardial perfusion SPECT (MPS) in obese patients...
  66. ncbi Automatic and visual reproducibility of perfusion and function measures for myocardial perfusion SPECT
    Yuan Xu
    Departments of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Nucl Cardiol 17:1050-7. 2010
    ....
  67. ncbi Quantitative analysis of myocardial perfusion SPECT anatomically guided by coregistered 64-slice coronary CT angiography
    Piotr J Slomka
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 50:1621-30. 2009
    ..We have developed an automated technique for MPS-CTA registration and demonstrate its utility for improved MPS quantification by guiding the coregistered physiologic (MPS) with anatomic CTA information...
  68. ncbi Concordance of coronary artery calcium estimates between MDCT and electron beam tomography
    Anthony L Daniell
    Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
    AJR Am J Roentgenol 185:1542-5. 2005
    ..4 mm3 for the volume score. CONCLUSION: Differences in CAC measurements using EBT and MDCT are similar to interscan differences in CAC measurements previously reported for EBT or for other MDCT scanners individually...
  69. ncbi Gated SPECT in assessment of regional and global left ventricular function: major tool of modern nuclear imaging
    Aiden Abidov
    Department of Imaging (Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif 90048, USA
    J Nucl Cardiol 13:261-79. 2006
  70. ncbi Quantification of serial changes in myocardial perfusion
    Piotr J Slomka
    Artificial Intelligence in Medicine Program, Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 45:1978-80. 2004
  71. ncbi Risk stratification in patients with remote prior myocardial infarction using rest-stress myocardial perfusion SPECT: prognostic value and impact on referral to early catheterization
    Michael J Zellweger
    Department of Imaging (Division of Nuclear Medicine, Cedars-Sinai Medical Center, The CSMC Burns and Allen Research Institute, Los Angeles, Calif. 90048, USA
    J Nucl Cardiol 9:23-32. 2002
    ..Patients with normal or mildly abnormal scan results or small MI in combination with absent or mild ischemia have a low risk for CD...
  72. ncbi Automatic global and regional phase analysis from gated myocardial perfusion SPECT imaging: application to the characterization of ventricular contraction in patients with left bundle branch block
    Serge D Van Kriekinge
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Nucl Med 49:1790-7. 2008
    ....
  73. ncbi Techniques for efficient, real-time, 3D visualization of multi-modality cardiac data using consumer graphics hardware
    David Levin
    Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Comput Med Imaging Graph 29:463-75. 2005
    ..We conclude that real-time rendering and processing of cardiac data can be implemented on consumer graphics cards...
  74. ncbi Transient ischemic dilation ratio: a universal high-risk diagnostic marker in myocardial perfusion imaging
    Aiden Abidov
    J Nucl Cardiol 14:497-500. 2007
  75. ncbi Recent technologic advances in nuclear cardiology
    James A Patton
    J Nucl Cardiol 14:501-13. 2007
  76. ncbi Myocardial perfusion and function: single photon emission computed tomography
    Christopher L Hansen
    J Nucl Cardiol 14:e39-60. 2007
  77. ncbi Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting
    Raffaele Giubbini
    Department of Nuclear Medicine, Spedali Civili di Brescia, Brescia, Italy
    Eur J Nucl Med Mol Imaging 31:1371-7. 2004
    ....
  78. ncbi Gated fluorine 18 fluorodeoxyglucose positron emission tomography: determination of global and regional left ventricular function and myocardial tissue characterization
    George Saab
    Cardiac PET Center, Division of Cardiology, University of Ottawa Heart Institute, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Nucl Cardiol 10:297-303. 2003
    ..Gated FDG-PET has the potential to assist in optimizing management of this patient population...
  79. ncbi The right stuff
    Guido Germano
    J Nucl Cardiol 9:226-8. 2002