Research Topics
Genomes and Genes | Deepti DhallSummaryAffiliation: Cedars-Sinai Medical Center Country: USA Publications
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Publications
Nested variant of urothelial carcinomaDeepti Dhall
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Arch Pathol Lab Med 131:1725-7. 2007....
Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendixLaura H Tang
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 32:1429-43. 2008..Surgical management with right hemicolectomy is recommended after appendectomy for most cases, particularly those with an adenocarcinoma component (groups B and C)...
Ki-67 proliferative index predicts progression-free survival of patients with well-differentiated ileal neuroendocrine tumorsDeepti Dhall
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Hum Pathol 43:489-95. 2012..In conclusion, the Ki-67 index predicts PFS of patients with ileal wNETs...
Murine model of Hirschsprung-associated enterocolitis II: Surgical correction of aganglionosis does not eliminate enterocolitisLifu Zhao
Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
J Pediatr Surg 45:206-11; discussion 211-2. 2010..The genetic and molecular mechanisms underlying these disorders are largely unknown...
Murine model of Hirschsprung-associated enterocolitis. I: phenotypic characterization with development of a histopathologic grading systemZhi Cheng
Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
J Pediatr Surg 45:475-82. 2010..The aim of the study was to characterize enterocolitis in the Ednrb-null (Ednrb-/-) mouse with aganglionosis of the colon and to develop and validate a semiquantitative histopathologic grading system to assess enterocolitis...
Splenic lymphopenia in the endothelin receptor B-null mouse: implications for Hirschsprung associated enterocolitisZhi Cheng
The Pediatric Surgery Laboratory, Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, 8635 W Third Street Suite 650 W, Los Angeles, CA 90048, USA
Pediatr Surg Int 27:145-50. 2011..The aim of the study was to describe and characterize a novel small spleen phenotype with splenic lymphopenia in the Ednrb-null (Ednrb-/-) mouse with aganglionosis known to also develop enterocolitis...
Goblet or signet ring cells: that is the questionHanlin L Wang
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
Adv Anat Pathol 16:247-54. 2009..This brief review summarizes these recent findings and raises a few issues that may need to be further addressed to better apply this classification to our practice...
S100P, von Hippel-Lindau gene product, and IMP3 serve as a useful immunohistochemical panel in the diagnosis of adenocarcinoma on endoscopic bile duct biopsyMary Levy
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Hum Pathol 41:1210-9. 2010....
Value of Islet 1 and PAX8 in identifying metastatic neuroendocrine tumors of pancreatic originJamie Koo
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Mod Pathol 25:893-901. 2012....
Interobserver and intraobserver variability in evaluating vascular invasion in hepatocellular carcinomaLifang Fan
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Gastroenterol Hepatol 25:1556-61. 2010..This study was designed to assess whether HCC could be accurately staged using vascular invasion as a staging parameter...
Adjuvant treatment of early colon cancer with micrometastases: results of a national surveyScott S Short
Cedars Sinai Medical Center, Los Angeles, California, USA
J Surg Oncol 106:119-22. 2012..Optimal adjuvant treatment for patients with Stage I/II colon cancer with micrometastases (MM) is unknown. Because there is no known adjuvant treatment-related benefit, we evaluated whether MM influenced treatment decisions...
Use of immunohistochemistry for IgG4 in the distinction of autoimmune pancreatitis from peritumoral pancreatitisDeepti Dhall
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Hum Pathol 41:643-52. 2010....
Anti-aging therapy with human growth hormone associated with metastatic colon cancer in a patient with Crohn's colitisGil Y Melmed
Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine, University of California, Los Angeles, California 90048, USA
Clin Gastroenterol Hepatol 6:360-3. 2008..The nonapproved use of human growth hormone (HGH) for anti-aging has been increasing. Theoretical concerns for neoplastic potentiation by HGH have been raised, but not proven clinically...
Diagnosis and treatment of pheochromocytoma in an academic hospital from 1997 to 2007Run Yu
Division of Endocrinology and Carcinoid and Neuroendocrine Tumor Center, Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90084, USA
Am J Med 122:85-95. 2009..We aimed to systemically study the diagnostic accuracy and treatment outcomes of pheochromocytoma and to reveal the causes and consequences of misdiagnosis (including both overdiagnosis and underdiagnosis)...
Nesidioblastosis and hyperplasia of alpha cells, microglucagonoma, and nonfunctioning islet cell tumor of the pancreas: review of the literatureRun Yu
Division of Endocrinology, Cedars Sinai Medical Cente, Los Angeles, CA 90048, USA
Pancreas 36:428-31. 2008..Nesidioblastosis and hyperplasia of alpha cells should be considered in the differential diagnosis of hyperglucagonemia. Somatostatin analog may be used to suppress glucagon secretion in alpha-cell hyperplasia...
Pheochromocytoma in patients suspected of harboring adrenal metastasis: management and clinical predictorsRun Yu
Division of Endocrinology and Carcinoid and Neuroendocrine Tumor Center, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Endocr Pract 14:967-72. 2008..To study clinical management of patients with suspected adrenal metastasis and to assess whether there are clinical predictors of pheochromocytoma in this patient population...
Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areasAnuradha Gopalan
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Mod Pathol 22:1066-74. 2009..Embryonal carcinoma-like high-grade' nuclear details are the most important morphological criterion for the diagnosis of embryonal carcinoma in difficult-to-classify areas...
Pancreatic neuroendocrine tumors in glucagon receptor-deficient miceRun Yu
Division of Endocrinology, Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
PLoS ONE 6:e23397. 2011..Our results further suggest that completely inhibiting glucagon signaling may not be a safe approach to treat diabetes...
Is nonsmall cell type high-grade neuroendocrine carcinoma of the tubular gastrointestinal tract a distinct disease entity?Jinru Shia
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 32:719-31. 2008..These tumors are clinically aggressive. Prospective studies using defined diagnostic criteria are needed to determine their biologic characteristics and optimal management...
Colorectal infantile myofibromatosis: an unusual cause of rectal prolapse and sigmoid colo-colonic intussusception: a case reportDeepti Dhall
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
Cases J 1:397. 2008..abstract:..
Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liverMary Levy
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Hum Pathol 43:695-701. 2012..Caution should thus be exercised when evaluating a GPC3-expressing hepatic neoplasm, particularly on a needle biopsy when the differential diagnosis includes poorly differentiated hepatocellular carcinoma or hepatoblastoma...
Application of immunohistochemistry to liver and gastrointestinal neoplasms: liver, stomach, colon, and pancreasStephen A Geller
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, 8700 Beverly Blvd, Room 8728, Los Angeles, CA 90048 0750, USA
Arch Pathol Lab Med 132:490-9. 2008..Recently, immunohistochemical evaluations have begun to allow pathologists to actively assist in determining prognosis and even in selecting therapies...
Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tractGeorge Miller
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Exp Clin Cancer Res 28:62. 2009..The pathogenesis of biliary cancers is ill-defined. This study investigates changes in gene expression and copy number in biliary cancers and correlates these changes with anatomical site of origin, histopathology and outcome...
A novel corrective pullthrough surgery in a mouse model of Hirschsprung's diseaseLifu Zhao
Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
J Pediatr Surg 44:759-66. 2009..The study aimed to develop a mouse model of post-pullthrough Hirschsprung's disease that will allow investigation of mechanisms that cause postoperative complications...
