E S Daar
Affiliation: Cedars-Sinai Medical Center
- Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment NetworkE S Daar
Cedars Sinai Burns and Allen Research Institute, University of California, Los Angeles, USA
Ann Intern Med 134:25-9. 2001..The optimal approach for diagnosing primary HIV-1 infection has not been defined...
- Virology and immunology of acute HIV type 1 infectionE S Daar
Cedars Sinai Burns and Allen Research Institute, Department of Medicine, UCLA School of Medicine, Los Angeles, California 90048, USA
AIDS Res Hum Retroviruses 14:S229-34. 1998..Investigations of what constitutes an effective immune response to HIV will be vital to the success of vaccine development in the future...
- Effects of plasma HIV RNA, CD4+ T lymphocytes, and the chemokine receptors CCR5 and CCR2b on HIV disease progression in hemophiliacs. Hemophilia Growth and Development StudyE S Daar
Cedars Sinai Burns and Allen Research Institute, Department of Medicine, and the University of California Los Angeles School of Medicine, 90048, USA
J Acquir Immune Defic Syndr 21:317-25. 1999..059). We conclude that plasma HIV RNA, CD4+ T lymphocytes, and CCR genotypes are correlated, and the protective affect of CCR2b against HIV disease progression is not completely explained by plasma HIV RNA or CD4+ T-lymphocyte number...
- Relation between HIV-1 and hepatitis C viral load in patients with hemophiliaE S Daar
Cedars Sinai Burns and Allen Research Institute, Division of Infectious Diseases, Department of Medicine, Los Angeles, CA 90048, USA
J Acquir Immune Defic Syndr 26:466-72. 2001..These results demonstrate that HIV-1/HCV co-infection is associated with a reduced likelihood of HCV clearance and that higher levels of HCV RNA are associated with increased hepatic inflammation...
- Hepatitis C virus load is associated with human immunodeficiency virus type 1 disease progression in hemophiliacsE S Daar
Cedars Sinai Burns and Allen Research Institute, Division of Infectious Diseases, B217, Department of Medicine, and University of California Los Angeles School of Medicine, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
J Infect Dis 183:589-95. 2001..10-2.51; P=.016) and an RR for AIDS-related mortality of 1.54 (95% CI, 1.03-2.30; P=.036). These findings emphasize the need for further research regarding the use of HIV-1- and HCV-specific therapy in coinfected individuals...
- Herpes simplex virus type 2 seroprevalence and incidence in acute and chronic HIV-1 infectionM Lagnese
Division of HIV Medicine and Infectious Diseases at Harbor UCLA Medical Center, Los Angeles, CA, USA
Int J STD AIDS 22:463-4. 2011..01); relative risk 0.72 (95% confidence interval [CI] 0.57-0.92). Since HSV-2 seroprevalence is lower in those newly HIV-infected, the diagnosis of early HIV infection may allow for counselling to reduce subsequent HSV-2 acquisition...
- Reduced antiretroviral drug susceptibility among patients with primary HIV infectionS J Little
Department of Medicine, University of California, San Diego, USA
JAMA 282:1142-9. 1999..The transmission of drug-resistant human immunodeficiency virus (HIV) has been documented, but the prevalence of such transmission is unknown...
- Seminal plasma HIV levels in men with asymptomatic sexually transmitted infectionsG Rieg
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center and the David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Int J STD AIDS 21:207-8. 2010..One patient who was not taking antiretrovirals had a 94% decline in SPVL after treatment of asymptomatic Chlamydia trachomatis urethritis, suggesting that asymptomatic infection may be a co-factor for HIV transmission...
- Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cellsD N Forthal
Division of Infectious Diseases, Department of Medicine, University of California, Irvine College of Medicine, Irvine, California, USA
J Virol 75:6953-61. 2001..HIV-1-specific antibody may be an important contributor to the early control of HIV viremia...
- Hepatitis C virus infection and neurocognitive functionM Soogoor
Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Los Angeles, CA, USA
Neurology 67:1482-5. 2006..After controlling for multiple factors, HCV monoinfection was not associated with deficits in adaptive behavior, intelligence, or attention/concentration...
- High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolatesE S Daar
Department of Medicine, Cedars Sinai Medical Center, University of California, Los Angeles School of Medicine 90048
Proc Natl Acad Sci U S A 87:6574-8. 1990..We conclude that unlike laboratory strains, primary HIV-1 isolates require high concentrations of sCD4 for neutralization. This phenomenon may pose a formidable problem for sCD4-based therapeutics in the treatment of HIV-1 infection...