Research Topics
| Sumeet ChughSummaryAffiliation: Cedars-Sinai Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
How to approach sudden cardiac arrest: current knowledge and clinical practiceSumeet S Chugh
The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Indian Heart J 63:341-6. 2011..The persisting low survival rates following SCA continue to emphasize that achievement of efficient risk stratification and primary prevention must remain our major target for management of SCA...
Determinants of prolonged QT interval and their contribution to sudden death risk in coronary artery disease: the Oregon Sudden Unexpected Death StudySumeet S Chugh
Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, USA
Circulation 119:663-70. 2009..We evaluated determinants of prolonged QTc and the relationship of prolonged QTc to SCD risk among patients with coronary artery disease in the general population...
The future of fellowship training in clinical cardiac electrophysiology: Program directors' perspective 2008Sumeet S Chugh
Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Heart Rhythm 6:1606-12. 2009....
Population-based analysis of sudden death in children: The Oregon Sudden Unexpected Death StudySumeet S Chugh
Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048
Heart Rhythm 6:1618-22. 2009..There is a lack of prospective population-based data regarding sudden death in children...
Women have a lower prevalence of structural heart disease as a precursor to sudden cardiac arrest: The Ore-SUDS (Oregon Sudden Unexpected Death Study)Sumeet S Chugh
The Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Am Coll Cardiol 54:2006-11. 2009..Our aim was to utilize a community-based approach to identify sex-related differences in risk factors for sudden cardiac arrest (SCA)...
Early identification of risk factors for sudden cardiac deathSumeet S Chugh
The Heart Institute, 5702 South Tower, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
Nat Rev Cardiol 7:318-26. 2010..This Review will discuss the potential utility of these markers as early identifiers of risk, and suggests a framework for the conduct of future studies for the discovery, validation, and deployment of novel SCD risk factors...
Epidemiology of sudden cardiac death: clinical and research implicationsSumeet S Chugh
Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA
Prog Cardiovasc Dis 51:213-28. 2008....
Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large U.S. communitySumeet S Chugh
Heart Rhythm Research Laboratory, Division of Cardiology, Oregon Health and Science University, Portland, Oregon 97239, USA
J Am Coll Cardiol 44:1268-75. 2004..To assess the validity of retrospective surveillance, a simultaneous comparison was made with a death certificate-based method of determining SCD incidence...
Factors associated with pulseless electric activity versus ventricular fibrillation: the Oregon sudden unexpected death studyCarmen Teodorescu
The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Circulation 122:2116-22. 2010..Given significantly lower survival from PEA versus VF, we comprehensively investigated PEA correlates by incorporating first-responder data with lifetime clinical history information...
Postmortem molecular screening in unexplained sudden deathSumeet S Chugh
Division of Cardiology, Oregon Health and Science University, Portland, 97239, USA
J Am Coll Cardiol 43:1625-9. 2004..We examined the prevalence of defects in arrhythmia-related candidate genes among patients with unexplained sudden cardiac death (SCD)...
Independent contribution of diabetes to increased prevalence and incidence of atrial fibrillationGregory A Nichols
Kaiser Permanente Center for Health Research, Portland, Oregon, USA
Diabetes Care 32:1851-6. 2009..We sought to compare the prevalence and incidence of atrial fibrillation in age- and sex-matched patients with and without type 2 diabetes...
Physical activity as a trigger of sudden cardiac arrest: the Oregon Sudden Unexpected Death StudyPulla R Reddy
Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon 97239, United States
Int J Cardiol 131:345-9. 2009..Vigorous physical activity has been suggested as a prominent trigger but has not been well-evaluated in the general population. We performed a community-based study to analyze the role of physical activity as a potential trigger of SCA...
A community-based evaluation of sudden death associated with therapeutic levels of methadoneSumeet S Chugh
Cardiac Arrhythmia Center, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland 97239, USA
Am J Med 121:66-71. 2008..Because of the established utility of this drug and with the eventual goal of enhancing safety of use, we performed a community-based study to evaluate this association...
Nonautomatic focal atrial tachycardia: characterization and ablation of a poorly understood arrhythmia in 38 patientsJanneke A E Kammeraad
Department of Pediatrics, Division of Cardiology, Oregon Health and Science University, 707 SW Gaines Road, Portland, OR 97201, USA
Pacing Clin Electrophysiol 26:736-42. 2003..In conclusion, NAFAT is a rare arrhythmia which predominantly affects women with no other associated cardiac disease. It mainly occurs in the right atrium, affects all ages and is amenable to catheter ablation...
Cardiac pathologic findings reveal a high rate of sudden cardiac death of undetermined etiology in younger womenSumeet S Chugh
Division of Cardiology, Oregon Health and Science University, Portland, Ore 97239, USA
Am Heart J 146:635-9. 2003..In contrast, the sudden cardiac death rate in age-matched men showed a decreasing trend (-2.8%). Due to under-representation of younger adults in published autopsy series, etiologies of sudden cardiac death merit further investigation...
Global remodeling of the ventricular interstitium in idiopathic myocardial fibrosis and sudden cardiac deathBenjamin T John
Division of Cardiology, Oregon Health and Science University, Portland, Oregon, USA
Heart Rhythm 1:141-9. 2004..CONCLUSION: IMF involves diffuse and heterogeneous remodeling of the ventricular interstitium, with a predilection for the LV inferior wall. TGF-beta(1) is a potential mediator of interstitial remodeling in IMF and SCD...
Arrhythmias after orthotopic heart transplantationEric C Stecker
Department of Cardiology, Oregon Health and Science University, Portland, 97201, USA
J Card Fail 11:464-72. 2005..At the same time, autonomic denervation and altered anatomy after transplantation complicate drug and device therapies...
Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death StudyEric C Stecker
Heart Rhythm Research Laboratory, Division of Cardiology, Oregon Health and Science University, Portland, Oregon
J Am Coll Cardiol 47:1161-6. 2006..The SCD cases with normal LV function had several distinguishing clinical characteristics. These findings support the aggressive development of alternative screening methods to enhance identification of patients at risk...
Allelic variants of SCN5A and risk of sudden cardiac arrest in patients with coronary artery diseaseEric C Stecker
Heart Rhythm Research Laboratory, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, 97239, USA
Heart Rhythm 3:697-700. 2006..Most sudden cardiac arrests occur in patients who have associated significant coronary artery disease (CAD), but current methods of risk stratification are inadequate...
Incidence of sudden cardiac arrest is higher in areas of low socioeconomic status: a prospective two year study in a large United States communityKyndaron Reinier
Heart Rhythm Research Laboratory, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR 97239, USA
Resuscitation 70:186-92. 2006..For effective deployment of strategies for community-based prevention such as the automated external defibrillator, neighborhood socioeconomic status is likely to be an important consideration...
Native QRS duration predicts the occurrence of arrhythmic events in ICD recipientsEric C Stecker
Heart Rhythm Research Laboratory, Division of Cardiology, UHN-62, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Europace 8:859-62. 2006..Extent of QRS prolongation could guide the decision to initiate prophylactic anti-arrhythmic therapy in ICD patients...
Genetic basis for chamber-specific ventricular phenotypes in the rat infarct modelSumeet S Chugh
Division of Cardiology, Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Cardiovasc Res 57:477-85. 2003..The existence of this and other such distinct electrophysiologic phenotypes in right (RV) vs. left ventricles (LV) could be explained by chamber-specific patterns of gene expression...
Research Grants
- Determinants of Sudden Death Risk with Left Ventricular HypertrophySumeet Chugh; Fiscal Year: 2009..A postmortem, case control approach will be used to compare LV myocardial interstitial remodeling in a subgroup of SCD cases with isolated LVH, vs. controls with isolated LVH, vs. normal controls. ..
- Determinants of Sudden Death Risk with Left Ventricular HypertrophySumeet S Chugh; Fiscal Year: 2010..A postmortem, case control approach will be used to compare LV myocardial interstitial remodeling in a subgroup of SCD cases with isolated LVH, vs. controls with isolated LVH, vs. normal controls. ..
- Determinants of Sudden Death Risk with Left Ventricular HypertrophySumeet Chugh; Fiscal Year: 2009..A postmortem, case control approach will be used to compare LV myocardial interstitial remodeling in a subgroup of SCD cases with isolated LVH, vs. controls with isolated LVH, vs. normal controls. ..
- Prolonged Ventricular Depolarization and Sudden Death in the CommunitySumeet S Chugh; Fiscal Year: 2010....
