Research Topics
Species | Mahul B AminSummaryAffiliation: Cedars-Sinai Medical Center Country: USA Publications
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Publications
Chromophobe renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 145 casesMahul B Amin
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 32:1822-34. 2008..The adverse presence of these features in a nephrectomy specimen with chromophobe RCC warrants active surveillance, and these patients may be candidates for adjuvant therapies as they become available...- Histological variants of urothelial carcinoma: diagnostic, therapeutic and prognostic implicationsMahul B Amin
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, 8700 BeverlyBlvd Suite 8728, Los Angeles, California 90048, USA
Mod Pathol 22:S96-S118. 2009..This review discusses the variants of urothelial carcinoma, outlining for each the diagnostic features, differential diagnostic considerations and the clinical significance... - Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinomaMahul B Amin
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 33:384-92. 2009..In light of the distinctive clinicopathologic features and a low but definite metastatic potential, this unique subtype of renal cell carcinoma deserves formal recognition in the contemporary classification of renal neoplasms... - Primary thyroid-like follicular carcinoma of the kidney: report of 6 cases of a histologically distinctive adult renal epithelial neoplasmMahul B Amin
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 33:393-400. 2009..Thyroid-like follicular renal cell carcinoma represents a unique histologic subtype of renal cell carcinoma of low malignant potential and its primary importance is to distinguish it from metastatic carcinoma from the thyroid... 
Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implicationsAdam Kuehn
Department of Pathology, Emory University Hospital, Atlanta, GA, USA
Am J Surg Pathol 31:1528-33. 2007....- A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear gradeGladell P Paner
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 34:1233-40. 2010.... - Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytomaAdeboye O Osunkoya
Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
Hum Pathol 40:206-10. 2009..It may be necessary to identify additional biomarkers to include with claudin-7 and claudin-8 in a larger immunohistochemical panel to improve diagnostic sensitivity and specificity... - Diagnostic use of antibody to smoothelin in the recognition of muscularis propria in transurethral resection of urinary bladder tumor (TURBT) specimensGladell P Paner
Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA
Am J Surg Pathol 34:792-9. 2010.... - Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic cautionGladell P Paner
Department of Pathology, Emory University Hospital, 1364 Clifton Road NE, G-167, Atlanta, GA 30322, USA
Am J Surg Pathol 30:13-9. 2006.... - Renal epithelial neoplasms: diagnostic applications of gene expression profilingAndrew N Young
Department of Pathology and Laboratory Medicine, Emory University School of Medicine Grady Memorial Hospital, 80 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
Adv Anat Pathol 15:28-38. 2008..Here, we review clinical features of kidney cancer, the WHO classification system, and the growing role of molecular classification for diagnosis, prognosis, and therapy of this disease... - Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profilingChristopher D Hornsby
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
Arch Pathol Lab Med 131:1541-6. 2007..Immunohistochemistry is useful for distinguishing chromophobe RCC from other subtypes of renal carcinoma, but no expression marker reliably separates chromophobe RCC from oncocytoma... - Further characterization of the muscle layers and lamina propria of the urinary bladder by systematic histologic mapping: implications for pathologic staging of invasive urothelial carcinomaGladell P Paner
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Am J Surg Pathol 31:1420-9. 2007.... - Urothelial neoplasms in patients 20 years or younger: a clinicopathological analysis using the world health organization 2004 bladder consensus classificationSamson W Fine
Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
J Urol 174:1976-80. 2005..Thus, the diagnostic category of PUNLMP allowed 43.5% of patients in this series to avoid being labeled with "cancer" at a young age... - Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationshipRuta Gupta
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 36:1265-78. 2012..The extremely poor prognosis and ongoing clinical trials with specific therapeutic protocols argue for their accurate distinction from other renal cell carcinoma subtypes... - A contemporary update on pathology reporting for prostate cancer: biopsy and radical prostatectomy specimensSamson W Fine
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Eur Urol 62:20-39. 2012..The diagnosis of and reporting parameters for prostate cancer (PCa) have evolved over time, yet they remain key components in predicting clinical outcomes... - Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinomaGladell P Paner
Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
Am J Surg Pathol 33:91-8. 2009.... - Current trends in molecular classification of adult renal tumorsAndrew N Young
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Urology 67:873-80. 2006 - Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologistsAnkur R Sangoi
Department of Pathology, Stanford University, Stanford, CA, USA
Am J Surg Pathol 34:1367-76. 2010..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy... - Neoplasms of the upper urinary tract: a review with focus on urothelial carcinoma of the pelvicalyceal system and aspects related to its diagnosis and reportingRuta Gupta
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Adv Anat Pathol 15:127-39. 2008..This review focuses on urothelial carcinoma of the upper tract highlighting issues related to its diagnosis, staging, and reporting... - Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathologyMathieu Latour
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
Am J Surg Pathol 32:1532-9. 2008..In conclusion, most of the small cribriform cancer foci seen on needle biopsy should be interpreted as Gleason pattern 4 and not pattern 3... 
Molecular classification of renal tumors by gene expression profilingAudrey N Schuetz
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Decatur, GA 30033, USA
J Mol Diagn 7:206-18. 2005..In summary, renal tumor subtypes were classified by distinct gene expression profiles, illustrating tumor pathobiology and translating into novel molecular bioassays using fixed tissue...- Paratesticular paraganglioma: a rare cause of an intrascrotal massRuta Gupta
Department of Pathology Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
Arch Pathol Lab Med 133:811-3. 2009..Herein the relevant histopathologic differential diagnoses are discussed along with a brief review of literature... - Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 casesJeffrey G Brown
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 34:942-9. 2010.... - Utility of a comprehensive immunohistochemical panel in the differential diagnosis of spindle cell lesions of the urinary bladderDanielle E Westfall
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 33:99-105. 2009.... - Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasmsRuta Gupta
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 33:241-7. 2009..These antibodies may reliably discriminate between clinically significant subtypes of RCC with overlapping cytoarchitectural features... - Current trends in the molecular classification of renal neoplasmsAndrew N Young
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
ScientificWorldJournal 6:2505-18. 2006..Here, we review clinical features of kidney cancer, the WHO classification system, and the growing role of molecular classification for diagnosis, prognosis, and therapy of this disease... - Beta defensin-1, parvalbumin, and vimentin: a panel of diagnostic immunohistochemical markers for renal tumors derived from gene expression profiling studies using cDNA microarraysAndrew N Young
Department of Pathology, Emory University, Atlanta, Georgia, USA
Am J Surg Pathol 27:199-205. 2003..This work demonstrates that a useful panel of immunohistochemical markers can be derived from differential gene expression profiles determined using cDNA microarrays... - The role of immunohistochemistry in the diagnosis of urinary bladder neoplasmsJesse K McKenney
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, USA
Semin Diagn Pathol 22:69-87. 2005.... - Update on the Gleason grading system for prostate cancer: results of an international consensus conference of urologic pathologistsJonathan I Epstein
Department of Pathology, Urology and Oncology, The Johns Hopkins Hospital, Weinberg Building Rm 2242, Baltimore, MD 21231, USA
Adv Anat Pathol 13:57-9. 2006..This article serves as a brief overview and summary of the proceedings that have been published in detail in recent literature... - Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasiaSatish K Tickoo
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 30:141-53. 2006..Acquired cystic disease-associated RCC is the commonest tumor subtype in ESRD, and biologically it appears to be more aggressive than the other tumor subtypes in ESRD... - Plasmacytoid urothelial carcinoma: detailed analysis of morphology with clinicopathologic correlation in 17 casesPriya Nigwekar
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 33:417-24. 2009..Distinction from metastatic carcinoma from other primary sites such as stomach and breast is critical due to differing therapeutic implications... - Pseudomyxoma peritonei associated with primary mucinous borderline tumor of the renal pelvicalyceal systemPriya Rao
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Arch Pathol Lab Med 133:1472-6. 2009..This case illustrates that, in a patient with pseudomyxoma peritonei, the absence of an appendiceal, gastrointestinal, or ovarian primary tumor raises the possibility of a primary neoplasm at an unusual site such as the kidney... - Renal cell carcinoma: assessment of key pathologic prognostic parameters and patient characteristics in 47,909 cases using the National Cancer Data BaseNalan Nese
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Ann Diagn Pathol 13:1-8. 2009.... - Loss of HOXC6 expression induces apoptosis in prostate cancer cellsSumathi Ramachandran
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Oncogene 24:188-98. 2005..Our data suggest that HOXC6 may be a novel potential therapeutic target for prostate cancer... - ICUD-EAU International Consultation on Bladder Cancer 2012: pathologyMahul B Amin
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Eur Urol 63:16-35. 2013..To present a summary of the 2nd International Consultation on Bladder Cancer recommendations on the pathology of bladder cancer using an evidence-based strategy... - Rhabdomyosarcoma of the urinary bladder in adults: predilection for alveolar morphology with anaplasia and significant morphologic overlap with small cell carcinomaGladell P Paner
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 32:1022-8. 2008.... - Best practice in diagnostic immunohistochemistry: prostate carcinoma and its mimics in needle core biopsiesGladell P Paner
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Arch Pathol Lab Med 132:1388-96. 2008..The availability of prostate cancer-associated and basal cell-associated markers has been an invaluable addition to diagnostic surgical pathology... - Rete testis-associated nodular steroid cell nests: description of putative pluripotential testicular hilus steroid cellsGladell P Paner
Department of Pathology, University of Chicago, Chicago, IL, USA
Am J Surg Pathol 35:505-11. 2011..We propose to name these proliferations rete testis-associated nodular steroid cell nests... - Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classificationJesse K McKenney
Department of Pathology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
Am J Surg Pathol 28:1289-98. 2004..This study suggests that adenoid cystic carcinomas are biologically indolent following prostatectomy but have a low risk of distant metastasis... - Non-epithelial neoplasms of the prostateGladell P Paner
Department of Pathology, University of Chicago, Chicago, IL, USA
Histopathology 60:166-86. 2012..This review addresses and updates the clinicopathological features of the entire spectrum of non-epithelial tumours with an approach to the histological diagnosis... - Pure epithelioid PEComas (so-called epithelioid angiomyolipoma) of the kidney: A clinicopathologic study of 41 cases: detailed assessment of morphology and risk stratificationNalan Nese
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Am J Surg Pathol 35:161-76. 2011..009 and 0.033, respectively). Our data of a large series with uniform definitional criteria confirm the malignant potential for pure epithelioid PEComas and provide adverse prognostic parameters for risk stratification in these patients... - Alveolar soft-part sarcoma of the urinary bladder with urethral recurrence: a unique case with emphasis on differential diagnoses and diagnostic utility of an immunohistochemical panel including TFE3Mahul B Amin
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Surg Pathol 30:1322-5. 2006.... - Urothelial (transitional cell) papilloma of the urinary bladder: a clinicopathologic study of 26 casesJesse K McKenney
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Mod Pathol 16:623-9. 2003..Urothelial papillomas are histologically and probably biologically distinctive tumors and merit distinction from other higher risk papillary neoplasms of the urinary bladder... - The many faces of urothelial carcinoma: an update with an emphasis on recently described variantsPriya Nigwekar
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Adv Anat Pathol 15:218-33. 2008..This review also includes a discussion on variants on which there is recent information available... - Carcinoma in situ of the urinary bladder: review of clinicopathologic characteristics with an emphasis on aspects related to molecular diagnostic techniques and prognosisNalan Nese
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, California, USA
J Natl Compr Canc Netw 7:48-57. 2009..From a clinical perspective, the principal determinants of outcome are extent of disease, involvement of prostatic urethra, response to therapy, and time to recurrence... - A contemporary update on pathology standards for bladder cancer: transurethral resection and radical cystectomy specimensDonna E Hansel
Department of Pathology, Cleveland Clinic, Cleveland, OH, USA
Eur Urol 63:321-32. 2013..Pathology standards for the diagnosis of bladder cancer (BCa) have recently evolved to better reflect patient diagnosis and clinical outcomes... - Comparative analysis of size estimation by mapping and counting number of blocks with ductal carcinoma in situ in breast excision specimensFarnaz Dadmanesh
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Arch Pathol Lab Med 133:26-30. 2009..The size of ductal carcinoma in situ (DCIS) is a significant predictor of local tumor recurrence and is used for selection of patients for conservative versus aggressive therapy. A standardized method for size assessment is lacking... - Osteoclast-rich undifferentiated carcinomas of the urinary tractDilek Baydar
Department of Pathology, The Johns Hopkins University School of Medicine, The James Brady Urological Institute, The Johns Hospital, Baltimore, MD 21231, USA
Mod Pathol 19:161-71. 2006.... - Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumorsMahul B Amin
Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
Mod Pathol 18:S131-45. 2005.... - The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic CarcinomaJonathan I Epstein
Department of Pathology, Urology and Oncology, Johns Hopkins Hospital, Baltimore, MD 21231, USA
Am J Surg Pathol 29:1228-42. 2005 - Colonic adenocarcinoma metastatic to the urinary tract versus primary tumors of the urinary tract with glandular differentiation: a report of 7 cases and investigation using a limited immunohistochemical panelPheroze Tamboli
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
Arch Pathol Lab Med 126:1057-63. 2002.... - Updated protocol for the examination of specimens from patients with carcinoma of the urinary bladder, ureter, and renal pelvisMahul B Amin
Department of Pathology, Emory University Hospital, Atlanta, GA, USA
Arch Pathol Lab Med 127:1263-79. 2003 - Intratubular large cell hyalinizing sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndromeThomas M Ulbright
Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
Am J Surg Pathol 31:827-35. 2007..Orchiectomy is indicated when there is evidence of an invasive tumor and may be necessary to control hormonal manifestations... - KRAS mutation testing in human cancers: The pathologist's role in the era of personalized medicineHanlin L Wang
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Adv Anat Pathol 17:23-32. 2010..Guidelines for KRAS testing that address these and other important points of consideration have recently been proposed in the United States and the European Union... - Utility of alpha-methylacyl coenzyme A racemase (p504s antibody) as a diagnostic immunohistochemical marker for cancerAziza Nassar
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Appl Immunohistochem Mol Morphol 13:252-5. 2005..It may be a useful adjunct to an immunohistochemical panel employed in the differential diagnosis of colon versus ovarian and breast carcinoma; the latter two infrequently express AMACR... - Potential utility of uroplakin III, thrombomodulin, high molecular weight cytokeratin, and cytokeratin 20 in noninvasive, invasive, and metastatic urothelial (transitional cell) carcinomasDouglas C Parker
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Surg Pathol 27:1-10. 2003..The results of the study indicate a role for an antibody panel that includes UROIII, THR, HMWCK, and CK20 in the diagnosis of urothelial tumors... - Pseudosarcomatous myofibroblastic proliferations of the bladder: a clinicopathologic study of 42 casesLara R Harik
Department of Pathology and Laboratory Medicine, Emory University Hospital, 1364 Clifton Road NE, Atlanta, GA 30322, USA
Am J Surg Pathol 30:787-94. 2006..Despite the Alk-1 gene translocation, there continues to be sufficient evidence for regarding these as distinct from the so-called inflammatory myofibroblastic tumor of childhood... - An approach to the diagnosis of flat intraepithelial lesions of the urinary bladder using the World Health Organization/ International Society of Urological Pathology consensus classification systemMahul B Amin
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Adv Anat Pathol 9:222-32. 2002.... - Mutations in the von Hippel-Lindau (VHL) gene refine differential diagnostic criteria in renal cell carcinomaNandita Barnabas
Department of Pathology, Henry Ford Health System, Detroit, Michigan 48202, USA
J Surg Oncol 80:52-60. 2002..Mutations in the VHL gene refine histologic diagnostic criteria in RCC serving as adjuncts to the present morphology based diagnosis of RCC... - Morphologic criteria for the diagnosis of prostatic adenocarcinoma in needle biopsy specimens. A study of 250 consecutive cases in a routine surgical pathology practiceMurali Varma
Department of Pathology, Henry Ford Hospital, Detroit, Mich, USA
Arch Pathol Lab Med 126:554-61. 2002.... - Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 casesRafael E Jimenez
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Surg Pathol 26:320-7. 2002..The accurate distinction between these two entities has clear prognostic and therapeutic implications...