- Simpson's paradox and calculation of number needed to treat from meta-analysisChristopher J Cates
Manor View Surgery, Bushey Health Centre, London Road, Bushey, Watford, UK
BMC Med Res Methodol 2:1. 2002..Calculation of numbers needed to treat (NNT) is more complex from meta-analysis than from single trials. Treating the data as if it all came from one trial may lead to misleading results when the trial arms are imbalanced...