Jackson Wright

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial
    Jackson T Wright
    Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Hypertens (Greenwich) 9:842-9. 2007
  2. ncbi request reprint Diuretic-induced increase in blood glucose levels: clinical implications
    Jackson T Wright
    General Clinical Research Center, Clinical Hypertension Program, Case Western Reserve University, Cleveland, OH 44106, USA
    J Cardiometab Syndr 2:133-5. 2007
  3. ncbi request reprint Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril
    Jackson T Wright
    General Clinical Research Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
    JAMA 293:1595-608. 2005
  4. ncbi request reprint Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial
    Jackson T Wright
    Case Western Reserve University, Department of Medicine, University Hospitals of Cleveland and the Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106 5014, USA
    JAMA 288:2421-31. 2002
  5. ncbi request reprint Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    Mahboob Rahman
    Division of Nephrology and Hypertension, Case Western Reserve University, University Hospitals of Cleveland, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA
    Arch Intern Med 165:936-46. 2005
  6. ncbi request reprint The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report
    Aram V Chobanian
    Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
    JAMA 289:2560-72. 2003
  7. pmc Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    Jackson T Wright
    Department of Medicine, General Clinical Research Center, Cleveland, Ohio, USA
    Arch Intern Med 168:207-17. 2008
  8. ncbi request reprint Cardiovascular outcomes in high-risk hypertensive patients stratified by baseline glomerular filtration rate
    Mahboob Rahman
    Case Western Reserve University, Cleveland, Ohio, USA
    Ann Intern Med 144:172-80. 2006
  9. ncbi request reprint Antihypertensive efficacy of night-time graded-release diltiazem versus morning amlodipine in African Americans
    Jackson T Wright
    Department of Medicine, Division of Hypertension, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Hypertens 17:734-42. 2004
  10. doi request reprint 24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study
    Jackson T Wright
    Case Western Reserve University, Cleveland, OH, USA
    J Clin Hypertens (Greenwich) 12:833-40. 2010

Research Grants

  1. GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
    Jackson Wright; Fiscal Year: 2004

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial
    Jackson T Wright
    Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Hypertens (Greenwich) 9:842-9. 2007
    ..The use of carvedilol compared with metoprolol did not effect glycemic control...
  2. ncbi request reprint Diuretic-induced increase in blood glucose levels: clinical implications
    Jackson T Wright
    General Clinical Research Center, Clinical Hypertension Program, Case Western Reserve University, Cleveland, OH 44106, USA
    J Cardiometab Syndr 2:133-5. 2007
  3. ncbi request reprint Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril
    Jackson T Wright
    General Clinical Research Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
    JAMA 293:1595-608. 2005
    ..Few cardiovascular outcome data are available for blacks with hypertension treated with angiotensin-converting enzyme (ACE) inhibitors or calcium channel blockers (CCBs)...
  4. ncbi request reprint Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial
    Jackson T Wright
    Case Western Reserve University, Department of Medicine, University Hospitals of Cleveland and the Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106 5014, USA
    JAMA 288:2421-31. 2002
    ..Hypertension is a leading cause of end-stage renal disease (ESRD) in the United States, with no known treatment to prevent progressive declines leading to ESRD...
  5. ncbi request reprint Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    Mahboob Rahman
    Division of Nephrology and Hypertension, Case Western Reserve University, University Hospitals of Cleveland, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA
    Arch Intern Med 165:936-46. 2005
    ....
  6. ncbi request reprint The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report
    Aram V Chobanian
    Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
    JAMA 289:2560-72. 2003
    ..Empathy builds trust and is a potent motivator. Finally, in presenting these guidelines, the committee recognizes that the responsible physician's judgment remains paramount...
  7. pmc Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    Jackson T Wright
    Department of Medicine, General Clinical Research Center, Cleveland, Ohio, USA
    Arch Intern Med 168:207-17. 2008
    ....
  8. ncbi request reprint Cardiovascular outcomes in high-risk hypertensive patients stratified by baseline glomerular filtration rate
    Mahboob Rahman
    Case Western Reserve University, Cleveland, Ohio, USA
    Ann Intern Med 144:172-80. 2006
    ..Chronic kidney disease is common in older patients with hypertension...
  9. ncbi request reprint Antihypertensive efficacy of night-time graded-release diltiazem versus morning amlodipine in African Americans
    Jackson T Wright
    Department of Medicine, Division of Hypertension, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Hypertens 17:734-42. 2004
    ....
  10. doi request reprint 24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study
    Jackson T Wright
    Case Western Reserve University, Cleveland, OH, USA
    J Clin Hypertens (Greenwich) 12:833-40. 2010
    ..9/-9.7 vs -14.2/-7.2; P=.20/P=.17). Based on ABP monitoring, valsartan/HCTZ is more effective than amlodipine/HCTZ in lowering ABP in Caucasians. In African Americans and Hispanics, both regimens are similarly effective...
  11. ncbi request reprint The management of hypertension in the African American patient
    Jackson T Wright
    Medicine, Case Western Reserve University, Cleveland, OH, USA
    J Clin Hypertens (Greenwich) 9:468-75. 2007
    ..The authors maintained full control of the discussion and the resulting content of this article; Novartis had no input in the choice of topic, speakers, or content...
  12. ncbi request reprint Successful blood pressure control in the African American Study of Kidney Disease and Hypertension
    Jackson T Wright
    Department of Medicine, Division of Hypertension, Case Western Reserve University, 10900 Euclid Ave, Wood Bldg, Room W 165, Cleveland, OH 44106 4982, USA
    Arch Intern Med 162:1636-43. 2002
    ..The African American Study of Kidney Disease and Hypertension (AASK) is an ongoing trial to evaluate the effect of blood pressure and choice of antihypertensive drug on the rate of decline of renal function...
  13. doi request reprint Drug treatment of hypertension in older hypertensives
    Arash Rashidi
    Department of Medicine, Case Western Reserve University, 29325 Health Campus Drive, Suit 3, Westlake, Ohio 44145, USA
    Clin Geriatr Med 25:235-44. 2009
    ..This article reviews the evidence for drug treatment in this population...
  14. ncbi request reprint Which drug should be used to treat patients with uncomplicated essential hypertension?
    Arash Rashidi
    Division of Nephrology and Hypertension, University Hospitals of Cleveland, Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, OH 44106 5401, USA
    Curr Opin Nephrol Hypertens 15:303-8. 2006
    ..To review recent data and guidelines on selecting the initial antihypertensive drug...
  15. ncbi request reprint Optimal treatment of hypertension and cardiovascular risk reduction in African Americans: treatment approaches for outpatients
    Jackson T Wright
    Clinical Hypertension Program, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106 4982, USA
    J Clin Hypertens (Greenwich) 5:18-25. 2003
    ....
  16. ncbi request reprint Determinants of salt sensitivity in black and white normotensive and hypertensive women
    Jackson T Wright
    Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Louis Stokes Cleveland VAMC, 11100 Euclid Ave, RB and C 7311, Cleveland, OH 44106 5041, USA
    Hypertension 42:1087-92. 2003
    ..In AA but not in whites, SS is positively associated with Na+i, Ca2+i, and the ratios of Na+i to K+i and of Ca2+i to Mg2+i...
  17. ncbi request reprint Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint
    Peter M Okin
    Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Hypertens 15:663-71. 2002
    ..However, the high mortality associated with LVH in African American patients makes more accurate ECG detection of LVH in these patients a clinical priority...
  18. pmc Rate of ESRD exceeds mortality among African Americans with hypertensive nephrosclerosis
    Tahira P Alves
    Department of Medicine, Division of Nephrology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Am Soc Nephrol 21:1361-9. 2010
    ..In conclusion, AASK participants were more likely to reach ESRD than to die...
  19. ncbi request reprint A 59-year-old man with racial characteristics
    Jackson T Wright
    General Clinical Research Center and Division of Nephrology and Hypertension, Case Western University, Cleveland, OH, USA
    J Clin Hypertens (Greenwich) 9:128-33. 2007
  20. ncbi request reprint A comparison of standardized versus "usual" blood pressure measurements in hemodialysis patients
    Mahboob Rahman
    Department of Medicine, Division of Hypertension, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Am J Kidney Dis 39:1226-30. 2002
    ..In light of these findings, efforts should be made to standardize blood pressure readings in hemodialysis units based on American Heart Association recommendations for blood pressure measurement...
  21. ncbi request reprint Differing effects of antihypertensive drugs on the incidence of diabetes mellitus among patients with hypertensive kidney disease
    Denyse Thornley-Brown
    Division of Nephrology, University of Alabama at Birmingham, USA
    Arch Intern Med 166:797-805. 2006
    ..We compared the incidence of type 2 diabetes mellitus (DM) and the composite outcome of impaired fasting glucose or DM (IFG/DM) for the African American Study of Kidney Disease and Hypertension interventions...
  22. ncbi request reprint Clinical events in high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid-lowering treatment to prevent heart attack trial
    Frans H H Leenen
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Hypertension 48:374-84. 2006
    ..Some, but not all, of these differences may be explained by less effective blood pressure control in the lisinopril arm...
  23. ncbi request reprint Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial
    Karen L Margolis
    HealthPartners Research Foundation PO Box 1524, Mailstop 21111R, Minneapolis, MN 55440 1524, USA
    Hypertension 50:854-61. 2007
    ....
  24. pmc Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial
    Vibha Bhatnagar
    University of California San Diego, La Jolla, USA
    J Hypertens 25:2082-92. 2007
    ..It has yet to be determined whether genotyping at the angiotensin-converting enzyme (ACE) locus is predictive of blood pressure response to an ACE inhibitor...
  25. ncbi request reprint Metabolic and clinical outcomes in nondiabetic individuals with the metabolic syndrome assigned to chlorthalidone, amlodipine, or lisinopril as initial treatment for hypertension: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent
    Henry R Black
    New York University School of Medicine, New York, New York, USA
    Diabetes Care 31:353-60. 2008
    ..Optimal initial antihypertensive drug therapy in people with the metabolic syndrome is unknown...
  26. ncbi request reprint Body weight changes with beta-blocker use: results from GEMINI
    Franz H Messerli
    St Luke s Roosevelt Hospital Center, New York City, NY 10019, USA
    Am J Med 120:610-5. 2007
    ....
  27. doi request reprint Thiazide-induced dysglycemia: call for research from a working group from the national heart, lung, and blood institute
    Barry L Carter
    Division of Clinical and Administrative Pharmacy, Rm 527, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
    Hypertension 52:30-6. 2008
  28. ncbi request reprint Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment t
    Barry R Davis
    The University of Texas School of Public Health, 1200 Herman Pressler Street, Houston, TX 77030, USA
    Ann Intern Med 137:313-20. 2002
    ..Sixty-eight percent (6167 of 9061) of the former patients and 59% (9081 of 15 256) of the latter patients were given additional medications to achieve a target blood pressure of less than 140/90 mm Hg...
  29. ncbi request reprint ALLHAT: setting the record straight
    Barry R Davis
    The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas 77030, USA
    Ann Intern Med 141:39-46. 2004
    ....
  30. ncbi request reprint Cardiovascular risk reduction in hypertensive black patients with left ventricular hypertrophy: the LIFE study
    Stevo Julius
    Department of Internal Medicine, Division of Hypertension, University of Michigan Medical Center, 3918 Taubman Center, Ann Arbor, MI 48109 0356, USA
    J Am Coll Cardiol 43:1047-55. 2004
    ..We report on a subanalysis of the effects of losartan and atenolol on cardiovascular events in black patients in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study...
  31. ncbi request reprint Clinical problems in the management of hypertension 1) Prehypertension: should we treat? 2)The very elderly: how should we treat
    Marvin Moser
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Hypertens (Greenwich) 6:262-6. 2004
  32. pmc Design and statistical aspects of the African American Study of Kidney Disease and Hypertension (AASK)
    Jennifer J Gassman
    Cleveland Clinic Department of Biostatistics, Ohio, 44195, USA
    J Am Soc Nephrol 14:S154-65. 2003
    ..The main secondary patient outcome is a composite including the following events: (1) reduction in GFR by 50%, (2) end-stage renal disease, or (3) death...
  33. ncbi request reprint Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial
    George L Bakris
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Ill, USA
    JAMA 292:2227-36. 2004
    ..Beta-blockers have been shown to decrease cardiovascular risk in patients with hypertension and type 2 diabetes mellitus (DM); however, some components of the metabolic syndrome are worsened by some beta-blockers...
  34. ncbi request reprint The rationale and design of the Glycemic Effects in Diabetes Mellitus Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) trial
    George L Bakris
    Rush Hypertension Center, Rush Medical Center, Suite 470, 1700 W Van Buren, Chicago, IL 60612, USA
    J Diabetes Complications 19:74-9. 2005
    ..The GEMINI trial, therefore, is the first large randomized trial to assess whether utilizing a third-generation beta-blocker yields a favorable metabolic profile in the patient with Type 2 diabetes and hypertension...
  35. ncbi request reprint Antihypertensive use and adherence and blood pressure stress response among black caregivers and non-caregivers
    Jalpa A Doshi
    University of Maryland, School of Pharmacy, Baltimore, MD 21201, USA
    Appl Nurs Res 16:266-77. 2003
    ..These findings contradict previous findings among white caregivers and non-caregivers and suggest different practice implications...
  36. ncbi request reprint Cardiovascular outcomes in the African American Study of Kidney Disease and Hypertension (AASK) Trial
    Keith Norris
    Charles R Drew University of Medicine and Science, Lynwood, CA 90262, USA
    Am J Kidney Dis 48:739-51. 2006
    ..Patients with chronic kidney disease are at increased risk for cardiovascular (CV) events...
  37. ncbi request reprint Success and predictors of blood pressure control in diverse North American settings: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    William C Cushman
    J Clin Hypertens (Greenwich) 4:393-404. 2002
    ..Achievable control rates in varied practice settings and geographic regions and factors that predict improved blood pressure control are not well identified...
  38. ncbi request reprint Angiotensin-converting-enzyme inhibitors and diuretics for hypertension
    Barry R Davis
    N Engl J Med 349:90-3; author reply 90-3. 2003
  39. ncbi request reprint The rationale and design of the AASK cohort study
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, 21205, USA
    J Am Soc Nephrol 14:S166-72. 2003
    ..Such results might eventually lead to new strategies that delay or prevent ESRD...
  40. ncbi request reprint Differential effects of beta-blockers on albuminuria in patients with type 2 diabetes
    George L Bakris
    Rush University Medical Center, Chicago, IL 60612, USA
    Hypertension 46:1309-15. 2005
    ..These differences cannot be explained by effects on blood pressure or alpha1-antagonism but may relate to antioxidant properties of carvedilol...
  41. ncbi request reprint Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    Aram V Chobanian
    Boston University School of Medicine, Boston, Mass, USA
    Hypertension 42:1206-52. 2003
    ..Positive experiences, trust in the clinician, and empathy improve patient motivation and satisfaction. This report serves as a guide, and the committee continues to recognize that the responsible physician's judgment remains paramount...
  42. ncbi request reprint How to treat hypertension in patients with coronary heart disease disease
    Marvin Moser
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Hypertens (Greenwich) 10:390-7. 2008
    ....
  43. ncbi request reprint The Metabolic Syndrome in African Americans: a review
    W Dallas Hall
    African American Lipid and Cardiovascular Council, USA
    Ethn Dis 13:414-28. 2003
    ..This comprehensive review is provided as part of the educational activities of the African-American Lipid and Cardiovascular Council (AALCC)...
  44. ncbi request reprint Should ethnicity serve as the basis for clinical trial design? Importance of race/ethnicity in clinical trials: lessons from the African-American Heart Failure Trial (A-HeFT), the African-American Study of Kidney Disease and Hypertension (AASK), and the A
    Anne L Taylor
    National Center of Excellence in Women s Health, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Circulation 112:3654-60; discussion 3666. 2005
  45. ncbi request reprint For the patient. What is the Metabolic Syndrome and why is it important?
    W Dallas Hall
    Ethn Dis 13:546. 2003
  46. ncbi request reprint A comparison of iothalamate-GFR and serum creatinine-based outcomes: acceleration in the rate of GFR decline in the African American Study of Kidney Disease and Hypertension
    Julia Lewis
    Nephrology Clinical Trials Center, Vanderbilt University Medical Center, 1211 21st Avenue South, 215 Medical Arts Building, Nashville, TN 37232 1371, USA
    J Am Soc Nephrol 15:3175-83. 2004
    ..This has important implications for the design of clinical trials with renal outcomes...
  47. ncbi request reprint Task Force 5: systemic hypertension
    Norman M Kaplan
    J Am Coll Cardiol 45:1346-8. 2005
  48. ncbi request reprint Ethnicity and blood pressure
    Suzanne Oparil
    Vascular Biology and Hypertension Program, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    J Clin Hypertens (Greenwich) 7:357-64. 2005
    ..This brief review will discuss recent findings that bear on the management of hypertension in these special patient groups...
  49. ncbi request reprint The metabolic syndrome: recognition and management
    W Dallas Hall
    Emory University School of Medicine, Atlanta, GA, USA
    Dis Manag 9:16-33. 2006
    ..Pharmacotherapy is typically needed for control of high blood pressure, hypercoagulability, and increased levels of blood glucose and triglycerides...
  50. doi request reprint Long-term effects of renin-angiotensin system-blocking therapy and a low blood pressure goal on progression of hypertensive chronic kidney disease in African Americans
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins Institutions, Johns Hopkins University, Baltimore, MD 21205 2223, USA
    Arch Intern Med 168:832-9. 2008
    ..A low blood pressure (BP) goal (BP, <130/80 mm Hg) is also recommended. The objective of this study was to determine the long-term effects of currently recommended BP therapy in 1094 African Americans with hypertensive CKD...

Research Grants5

  1. GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
    Jackson Wright; Fiscal Year: 2004
    ..To this end, careful analytic attention will be paid to the development of improved phenotype definition, as well as to the consideration of gene-gene and gene-environment interaction. ..