Daniel W Wesson

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Parallel odor processing by two anatomically distinct olfactory bulb target structures
    Colleen A Payton
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
    PLoS ONE 7:e34926. 2012
  2. ncbi request reprint A breath of new life into human social cognition
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, School of Medicine, 2109 Adelbert Road Cleveland, OH 44106, USA
    Chem Senses 39:273-5. 2014
  3. doi request reprint Response to assini et Al
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA Electronic address
    Curr Biol 23:R997-8. 2013
  4. doi request reprint Sniffing behavior communicates social hierarchy
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA
    Curr Biol 23:575-80. 2013
  5. pmc Chronic anti-murine Aβ immunization preserves odor guided behaviors in an Alzheimer's β-amyloidosis model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 237:96-102. 2013
  6. pmc Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 31:15962-71. 2011
  7. pmc Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
    Jose Morales-Corraliza
    Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Neurobiol Aging 34:137-45. 2013
  8. pmc Response to comments on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"
    Gary E Landreth
    Alzheimer Research Laboratory, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Science 340:924-g. 2013
  9. pmc Olfactory dysfunction correlates with amyloid-beta burden in an Alzheimer's disease mouse model
    Daniel W Wesson
    Emotional Brain Institute and Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:505-14. 2010
  10. pmc Respiratory and sniffing behaviors throughout adulthood and aging in mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Behav Brain Res 223:99-106. 2011

Collaborators

Detail Information

Publications22

  1. pmc Parallel odor processing by two anatomically distinct olfactory bulb target structures
    Colleen A Payton
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
    PLoS ONE 7:e34926. 2012
    ..We predict that the olfactory code follows a distributed processing stream in transmitting behaviorally and perceptually-relevant information from low-level stations...
  2. ncbi request reprint A breath of new life into human social cognition
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, School of Medicine, 2109 Adelbert Road Cleveland, OH 44106, USA
    Chem Senses 39:273-5. 2014
    ..These findings raise important and exciting questions about the possible roles of sniffing in the social context and highlight the need for chemosensory researchers to reconsider the significance of sniffing. ..
  3. doi request reprint Response to assini et Al
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA Electronic address
    Curr Biol 23:R997-8. 2013
    ..Here I attempt to frame these two supportive studies together with the goal of a greater understanding of animal social cognition and communication. ..
  4. doi request reprint Sniffing behavior communicates social hierarchy
    Daniel W Wesson
    Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA
    Curr Biol 23:575-80. 2013
    ..Together, these findings demonstrate that rodents utilize sniffing behaviors communicatively, not only to collect [6, 10-14] but also to convey information...
  5. pmc Chronic anti-murine Aβ immunization preserves odor guided behaviors in an Alzheimer's β-amyloidosis model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 237:96-102. 2013
    ..Further, these results provide mechanistic insights into olfactory dysfunction as a biomarker for AD by yielding evidence that focal reductions of Aβ may be sufficient to preserve olfaction...
  6. pmc Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 31:15962-71. 2011
    ....
  7. pmc Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
    Jose Morales-Corraliza
    Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Neurobiol Aging 34:137-45. 2013
    ....
  8. pmc Response to comments on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"
    Gary E Landreth
    Alzheimer Research Laboratory, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Science 340:924-g. 2013
    ..However, we concluded that plaque burden is functionally unrelated to improved cognition and memory elicited by bexarotene...
  9. pmc Olfactory dysfunction correlates with amyloid-beta burden in an Alzheimer's disease mouse model
    Daniel W Wesson
    Emotional Brain Institute and Center for Dementia Research, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:505-14. 2010
    ..Furthermore, these results present the odor cross-habituation test as a powerful behavioral assay, which reflects Abeta deposition and thus may serve to monitor the efficacy of therapies aimed at reducing Abeta...
  10. pmc Respiratory and sniffing behaviors throughout adulthood and aging in mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Behav Brain Res 223:99-106. 2011
    ..These results show that odor-orienting responses are minimally impacted throughout aging in mice, and suggest that the olfactomotor network is mostly spared of insults due to aging...
  11. doi request reprint Encoding and representation of intranasal CO2 in the mouse olfactory cortex
    Kaitlin S Carlson
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    J Neurosci 33:13873-81. 2013
    ..These data provide mechanistic insights into the influences of trigeminal information on odor processing and place constraints on models of olfactory-trigeminal sensory integration. ..
  12. pmc ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models
    Paige E Cramer
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Science 335:1503-6. 2012
    ..Thus, RXR activation stimulates physiological Aβ clearance mechanisms, resulting in the rapid reversal of a broad range of Aβ-induced deficits...
  13. pmc Mechanisms of neural and behavioral dysfunction in Alzheimer's disease
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, New York University School of Medicine, Orangeburg, NY 10962, USA
    Mol Neurobiol 43:163-79. 2011
    ....
  14. pmc Sniffing out the contributions of the olfactory tubercle to the sense of smell: hedonics, sensory integration, and more?
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Neurosci Biobehav Rev 35:655-68. 2011
    ..Together, the information within this review highlights an understudied yet potentially critical component in central odor processing...
  15. pmc Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
    Behav Brain Res 216:408-13. 2011
    ..These results suggest that the APP gene plays a role in affiliative behaviors and are discussed in relation to disorders characteristic of mutations in the APP gene and in affective dysfunction, including Alzheimer's disease...
  16. doi request reprint Age-dependent alterations in the number, volume, and localization of islands of Calleja within the olfactory tubercle
    Stacey Adjei
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Neurobiol Aging 34:2676-82. 2013
    ..We predict that modifications among the IC throughout aging and age-related neurodegenerative disorders might be a novel contributor to pathological changes in olfactory cortex function and olfactory perception. ..
  17. doi request reprint Distributed auditory sensory input within the mouse olfactory cortex
    Adrienn G Varga
    Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA
    Eur J Neurosci 37:564-71. 2013
    ..e. that entering the OT and PCX) is subject to auditory sensory input in a manner that may modulate odor information processing, odor-guided behaviors and perception...
  18. pmc Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle
    Daniel W Wesson
    Emotional Brain Institute, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
    J Neurosci 30:3013-21. 2010
    ..Thus, the tubercle presents itself as a source for direct multimodal convergence within an early stage of odor processing and may serve as a seat for psychophysical interactions between smells and sounds...
  19. ncbi request reprint Odor- and state-dependent olfactory tubercle local field potential dynamics in awake rats
    Kaitlin S Carlson
    Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio and
    J Neurophysiol 111:2109-23. 2014
    ..Together, these data provide initial insights into the network activity of the OT in the awake rat, including spontaneous rhythmicity, odor-evoked modulation, connectivity with upstream sensory input, and state-dependent modulation. ..
  20. pmc Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis
    Dun Sheng Yang
    Nathan Kline Institute, Orangeburg, NY, USA
    Autophagy 7:788-9. 2011
    ..Our findings underscore the pathogenic significance of autophagic-lysosomal dysfunction in AD and demonstrate the value of reversing this dysfunction as an innovative therapeautic strategy for AD...