Albert Waldo

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. doi request reprint Safety of the open-irrigated ablation catheter for radiofrequency ablation: safety analysis from six clinical studies
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Pacing Clin Electrophysiol 35:1081-9. 2012
  2. ncbi request reprint Anticoagulation: stroke prevention in patients with atrial fibrillation
    Albert L Waldo
    Department of Medicine, Division of Cardiovascular Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, Cleveland, OH, USA
    Med Clin North Am 92:143-59, xi. 2008
  3. ncbi request reprint Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation
    Albert L Waldo
    Division of Cardiology, Case Western University University Hospitals of Cleveland, Cleveland, Ohio 44106 5038, USA
    J Am Coll Cardiol 46:1729-36. 2005
  4. doi request reprint Anticoagulation: stroke prevention in patients with atrial fibrillation
    Albert L Waldo
    Department of Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, 11100 Euclid Avenue, MS LKS 5038, Cleveland, OH 44106 5038, USA
    Cardiol Clin 27:125-35, ix. 2009
  5. doi request reprint Inter-relationships of atrial fibrillation and atrial flutter mechanisms and clinical implications
    Albert L Waldo
    Department of Medicine, Division of Cardiovascular Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio 44106 5038, USA
    J Am Coll Cardiol 51:779-86. 2008
  6. ncbi request reprint A perspective on antiarrhythmic drug therapy to treat atrial fibrillation: there remains an unmet need
    Albert L Waldo
    Division of Cardiology, Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    Am Heart J 151:771-8. 2006
  7. ncbi request reprint Long-term pharmacologic management of atrial fibrillation in the elderly
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Am J Geriatr Cardiol 11:233-44; quiz 244-6. 2002
  8. ncbi request reprint New possibilities in anticoagulant management of atrial fibrillation
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA
    Rev Cardiovasc Med 5:S30-8. 2004
  9. ncbi request reprint Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava
    Niraj Varma
    Department of Cardiac Electrophysiology, Cleveland, Ohio 44118, USA
    Heart Rhythm 1:82-7. 2004
  10. ncbi request reprint A perspective on rate control in the treatment of atrial fibrillation
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, and University Hospitals of Cleveland, Cleveland, Ohio 44106 5038, USA
    Clin Cardiol 27:121-4. 2004

Research Grants

  1. ATRIAL FIBRILLATION AND FLUTTER IN A MODEL
    Albert Waldo; Fiscal Year: 1999
  2. STUDIES OF ATRAIL FLUTTER IN A MODEL
    Albert Waldo; Fiscal Year: 1993
  3. Studies of Atrial Fibrillation in Patients
    Albert Waldo; Fiscal Year: 2006

Collaborators

Detail Information

Publications41

  1. doi request reprint Safety of the open-irrigated ablation catheter for radiofrequency ablation: safety analysis from six clinical studies
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Pacing Clin Electrophysiol 35:1081-9. 2012
    ....
  2. ncbi request reprint Anticoagulation: stroke prevention in patients with atrial fibrillation
    Albert L Waldo
    Department of Medicine, Division of Cardiovascular Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, Cleveland, OH, USA
    Med Clin North Am 92:143-59, xi. 2008
    ..AF is the most common and important cause of stroke resulting from any cause. This article considers the risks for and anticoagulation prophylaxis against embolic stroke in patients with AF...
  3. ncbi request reprint Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation
    Albert L Waldo
    Division of Cardiology, Case Western University University Hospitals of Cleveland, Cleveland, Ohio 44106 5038, USA
    J Am Coll Cardiol 46:1729-36. 2005
    ..The purpose of this study was to determine both treatment gaps and predictors of warfarin use in atrial fibrillation (AF) patients enrolled in a national multicenter study...
  4. doi request reprint Anticoagulation: stroke prevention in patients with atrial fibrillation
    Albert L Waldo
    Department of Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, 11100 Euclid Avenue, MS LKS 5038, Cleveland, OH 44106 5038, USA
    Cardiol Clin 27:125-35, ix. 2009
    ..The presence of AF confers a fivefold increased risk for stroke. AF is the most common and important cause of stroke. This article considers the risks for and anticoagulation prophylaxis against embolic stroke in patients who have AF...
  5. doi request reprint Inter-relationships of atrial fibrillation and atrial flutter mechanisms and clinical implications
    Albert L Waldo
    Department of Medicine, Division of Cardiovascular Medicine, Case Western Reserve University University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio 44106 5038, USA
    J Am Coll Cardiol 51:779-86. 2008
    ..In short, there are probably several mechanisms of AF, 1 of which is due to a very rapid AFL causing fibrillatory conduction. All of these interactions of AF and AFL have important clinical implications...
  6. ncbi request reprint A perspective on antiarrhythmic drug therapy to treat atrial fibrillation: there remains an unmet need
    Albert L Waldo
    Division of Cardiology, Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    Am Heart J 151:771-8. 2006
    ..Therein lie an important clinical dilemma and an unmet need. Sinus rhythm is good, but we need better ways to maintain it effectively and safely...
  7. ncbi request reprint Long-term pharmacologic management of atrial fibrillation in the elderly
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Am J Geriatr Cardiol 11:233-44; quiz 244-6. 2002
    ..A clinically reasoned approach is suggested in the presence of coronary artery disease, left ventricular dysfunction /congestive heart failure, or hypertension based largely on the risk/benefit profile of the drugs...
  8. ncbi request reprint New possibilities in anticoagulant management of atrial fibrillation
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA
    Rev Cardiovasc Med 5:S30-8. 2004
    ..5%) with elevation of both alanine aminotransferase (ALT) and bilirubin levels can be managed safely, thereby making ximelagatran a promising option for preventing thromboembolism in patients with atrial fibrillation at risk for stroke...
  9. ncbi request reprint Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava
    Niraj Varma
    Department of Cardiac Electrophysiology, Cleveland, Ohio 44118, USA
    Heart Rhythm 1:82-7. 2004
    ..The implications of this congenital abnormality on posterior barriers maintaining the atrial flutter circuit are discussed...
  10. ncbi request reprint A perspective on rate control in the treatment of atrial fibrillation
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, and University Hospitals of Cleveland, Cleveland, Ohio 44106 5038, USA
    Clin Cardiol 27:121-4. 2004
    ..Pursuit of rate or rhythm control should be decided on a case-by-case basis...
  11. ncbi request reprint Azd7009: a new antiarrhythmic drug with predominant effects on the atria effectively terminates and prevents reinduction of atrial fibrillation and flutter in the sterile pericarditis model
    Robert N Goldstein
    Case Western Reserve University University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Cardiovasc Electrophysiol 15:1444-50. 2004
    ..We tested the hypothesis that AZD7009 terminates induced atrial fibrillation (AF) and flutter (AFL) and prevents their reinduction, and that effects on refractoriness, conduction, and excitability are predominantly on the atria...
  12. ncbi request reprint Use of fast fourier transform analysis of atrial electrograms for rapid characterization of atrial activation-implications for delineating possible mechanisms of atrial tachyarrhythmias
    Kyungmoo Ryu
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA
    J Cardiovasc Electrophysiol 17:198-206. 2006
    ....
  13. doi request reprint Vanoxerine, a new drug for terminating atrial fibrillation and flutter
    Naomichi Matsumoto
    Department of Medicine, Division of Cardiology, Case Western Reserve University, School of Medicine, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Cardiovasc Electrophysiol 21:311-9. 2010
    ..Therefore, we proposed that vanoxerine might be antiarrhythmic. In these studies, we tested the hypothesis that vanoxerine would terminate induced atrial fibrillation (AF) and atrial flutter (AFL) in dogs with sterile pericarditis (SP)...
  14. ncbi request reprint Effects of sterile pericarditis on connexins 40 and 43 in the atria: correlation with abnormal conduction and atrial arrhythmias
    Kyungmoo Ryu
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Physiol Heart Circ Physiol 293:H1231-41. 2007
    ..The transmural gradient in the volume fraction of Cx40 and Cx43 in SP is associated with markedly abnormal atrial conduction and is likely an important factor in the vulnerability to induction and maintenance of AFL/AF in SP...
  15. pmc Termination of a tachyarrhythmia by flunarizine is not a specific marker for a triggered mechanism
    SERGEY A VITEBSKIY
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Heart Rhythm 4:1544-52. 2007
    ..Prior studies have indicated that tachyarrhythmia termination by flunarizine demonstrates a triggered mechanism. This concept was not confirmed in atrial tachyarrhythmias...
  16. doi request reprint Fixed intercaval block in the setting of atrial fibrillation promotes the development of atrial flutter
    Hanh M Bui
    Department of Medicine, Division of Cardiology, Case Western Reserve University University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Heart Rhythm 5:1745-52. 2008
    ..In the canine sterile pericarditis model, typically only atrial fibrillation (AF) is inducible on postoperative day 2...
  17. ncbi request reprint Mechanisms of atrial flutter and atrial fibrillation: distinct entities or two sides of a coin?
    Albert L Waldo
    Division of Cardiology, Department of Medicine, MS 5038, University Hospitals of Cleveland Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5038, USA
    Cardiovasc Res 54:217-29. 2002
  18. ncbi request reprint Inter-relationships between atrial flutter and atrial fibrillation
    Albert L Waldo
    Department of Medicine, Case Western Reserve University University Hospitals of Cleveland, Cleveland, Ohio 44106 50388, USA
    Pacing Clin Electrophysiol 26:1583-96. 2003
    ..Unstable reentrant circuits can also do the same thing. In short, it appears that there are several mechanisms of atrial fibrillation, one of which is due to a form of very rapid atrial flutter...
  19. ncbi request reprint The interrelationship between atrial fibrillation and atrial flutter
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Prog Cardiovasc Dis 48:41-56. 2005
    ..In sum, atrial fibrillation and atrial flutter have an important interrelationship...
  20. ncbi request reprint Should we control rate or rhythm in atrial fibrillation?
    Albert L Waldo
    Department of Medicine, Case Western Reserve University, and University Hospitals of Cleveland, Cleveland, Ohio, USA
    J Cardiovasc Electrophysiol 14:1122-3. 2003
  21. ncbi request reprint Prednisone prevents inducible atrial flutter in the canine sterile pericarditis model
    Robert N Goldstein
    Division of Cardiology, Department of Medicine, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Cardiovasc Electrophysiol 19:74-81. 2008
    ..We tested the hypothesis that suppression of the inflammatory response with steroids would significantly modify the inducibility of postoperative AF/AFL in the canine sterile pericarditis model...
  22. ncbi request reprint Mechanisms of atrial fibrillation
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Cardiovasc Electrophysiol 14:S267-74. 2003
    ..However, a precise understanding of the mechanism(s) of AF in patients is not yet available...
  23. ncbi request reprint From bedside to bench: entrainment and other stories
    Albert L Waldo
    Department of Medicine, Division of Cardiology, Case Western Reserve University University Hospitals of Cleveland, Ohio 44106, USA
    Heart Rhythm 1:94-106. 2004
    ..Moreover, the principles of entrainment have also been applied clinically to assist in effective application of antitachycardia pacing and catheter ablation techniques...
  24. ncbi request reprint Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations
    Jayakumar Sahadevan
    Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, The Louis B Stokes Veterans Administration Medical Center, Cleveland, Ohio 44106, USA
    Circulation 110:3293-9. 2004
    ....
  25. doi request reprint Frequency analysis of atrial electrograms identifies conduction pathways from the left to the right atrium during atrial fibrillation-studies in two canine models
    Kyungmoo Ryu
    Department of Biomedical Engineering, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    J Cardiovasc Electrophysiol 20:667-74. 2009
    ..Computation time for FFT analysis for each AF episode took less than 5 minutes. CONCLUSION: FFT analysis allowed rapid and reliable detection of the LA-to-RA conduction pathways in AF generated by a stable and rapid LA driver...
  26. pmc Vanoxerine: cellular mechanism of a new antiarrhythmic
    Antonio E Lacerda
    ChanTest Corporation, Cleveland, Ohio 44128, USA
    J Cardiovasc Electrophysiol 21:301-10. 2010
    ..1) cardiac potassium channel. Consequently,we hypothesized that vanoxerine might also be a potent blocker of cardiac calcium (Ca) and sodium (Na) currents, and would not affect transmural dispersion of repolarization...
  27. ncbi request reprint Stroke prevention in atrial fibrillation
    Albert L Waldo
    JAMA 290:1093-5. 2003
  28. ncbi request reprint Occurrence and characteristics of stroke events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) study
    David G Sherman
    University of Texas Health Science Center, San Antonio, USA
    Arch Intern Med 165:1185-91. 2005
    ..The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Study was a multicenter comparison of high-risk patients with AF who were randomized to either a sinus rhythm control or a rate control strategy...
  29. ncbi request reprint Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study
    Scott D Corley
    Axio Research Corporation, Seattle, Wash, USA
    Circulation 109:1509-13. 2004
    ..This article reports an "on-treatment" analysis of the relationship of survival to cardiac rhythm and treatment as they changed over time...
  30. ncbi request reprint Treatment of venous thromboembolism: adherence to guidelines and impact of physician knowledge, attitudes, and beliefs
    Joseph A Caprini
    Evanston Northwestern Healthcare and Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    J Vasc Surg 42:726-33. 2005
    ..To assess the treatment of venous thromboembolism (VTE) in hospitalized patients enrolled in a national, multicenter database...
  31. ncbi request reprint Factors affecting bleeding risk during anticoagulant therapy in patients with atrial fibrillation: observations from the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study
    John P Dimarco
    Cardiovascular Division, University of Virginia Health System, Charlottesville, VA 22908, USA
    Am Heart J 149:650-6. 2005
    ..Bleeding is the major complication of anticoagulant treatment, and the relative risks for bleeding vs stroke must be considered when starting anticoagulation...
  32. doi request reprint ACC/AHA/Physician Consortium 2008 clinical performance measures for adults with nonvalvular atrial fibrillation or atrial flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physici
    N A Mark Estes
    Circulation 117:1101-20. 2008
  33. ncbi request reprint International consensus on nomenclature and classification of atrial fibrillation: A collaborative project of the Working Group on Arrhythmias and the Working Group of Cardiac Pacing of the European Society of Cardiology and the North American Society of
    Samuel Levy
    Hopital Nord, Division of Cardiology, 13015 Marseille, France
    J Cardiovasc Electrophysiol 14:443-5. 2003
  34. doi request reprint Rhythm control versus rate control for atrial fibrillation and heart failure
    Denis Roy
    Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
    N Engl J Med 358:2667-77. 2008
    ..However, the benefits and risks of this approach have not been adequately studied...
  35. doi request reprint ACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults with Nonvalvular Atrial Fibrillation or Atrial Flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physici
    N A Mark Estes
    J Am Coll Cardiol 51:865-84. 2008
  36. ncbi request reprint The impact of asymptomatic atrial fibrillation
    Elizabeth S Kaufman
    J Am Coll Cardiol 43:53-4. 2004
  37. ncbi request reprint Catheter ablation of atrial fibrillation: a treatment frontier
    Michael Domanski
    J Interv Card Electrophysiol 15:141-3. 2006
  38. ncbi request reprint Role of permanent pacing to prevent atrial fibrillation: science advisory from the American Heart Association Council on Clinical Cardiology (Subcommittee on Electrocardiography and Arrhythmias) and the Quality of Care and Outcomes Research Interdisciplin
    Bradley P Knight
    Circulation 111:240-3. 2005
    ..At present, permanent pacing to prevent AF is not indicated; however, additional studies are ongoing, which will help to clarify the role of permanent pacing for AF...
  39. ncbi request reprint Antithrombotic therapy practices in US hospitals in an era of practice guidelines
    Victor F Tapson
    Division of Pulmonary Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Arch Intern Med 165:1458-64. 2005
    ..Antithrombotic therapy is efficacious for the prevention of thromboembolic disease, but it necessitates careful risk-benefit assessment...
  40. ncbi request reprint Clinical factors that influence response to treatment strategies in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study
    Anne B Curtis
    University of Florida, Box 100277, 1600 SW Archer Rd, Gainesville, FL 32610, USA
    Am Heart J 149:645-9. 2005
    ..The primary outcome of the trial showed no overall difference in survival between strategies. However, there may be important patient subgroups for which there are identifiable differences in outcome with 1 of the 2 strategies...
  41. ncbi request reprint Atrial fibrillation-atrial flutter interactions: clinical implications for ablation
    Albert L Waldo
    Circulation 116:2774-5. 2007

Research Grants17

  1. ATRIAL FIBRILLATION AND FLUTTER IN A MODEL
    Albert Waldo; Fiscal Year: 1999
    ..The proposed studies should provide important new information to assist in improved understanding and treatment of patients suffering from these rhythm disorders. ..
  2. STUDIES OF ATRAIL FLUTTER IN A MODEL
    Albert Waldo; Fiscal Year: 1993
    ..The proposed studies should provide important new information to assist in improved understanding and treatment of patients suffering from this abnormality...
  3. Studies of Atrial Fibrillation in Patients
    Albert Waldo; Fiscal Year: 2006
    ....