Derek J Taylor

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA
    Derek J Taylor
    Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 410:10-7. 2011
  2. pmc Coordinated interactions of multiple POT1-TPP1 proteins with telomere DNA
    Mark Corriveau
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106, USA
    J Biol Chem 288:16361-70. 2013

Collaborators

  • Mark Corriveau
  • Michael R Mullins
  • Diane Baus
  • Michael E Harris

Detail Information

Publications2

  1. pmc Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA
    Derek J Taylor
    Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 410:10-7. 2011
    ..The results revealed that POT1-N and POT1-TPP1 can completely coat long telomeric ssDNA substrates. Furthermore, we show that ssDNA coated with human POT1-TPP1 heterodimers forms compact, potentially ordered structures...
  2. pmc Coordinated interactions of multiple POT1-TPP1 proteins with telomere DNA
    Mark Corriveau
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106, USA
    J Biol Chem 288:16361-70. 2013
    ..Together, these data suggest that POT1-TPP1 binds telomeric DNA in a coordinated manner to facilitate assembly of the nucleoprotein complexes into a state that is more accessible to enzymatic activity...