Derek J Taylor

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA
    Derek J Taylor
    Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 410:10-7. 2011
  2. pmc Multiple facets of TPP1 in telomere maintenance
    Malligarjunan Rajavel
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland OH 44106, USA
    Biochim Biophys Acta 1844:1550-9. 2014
  3. pmc Coordinated interactions of multiple POT1-TPP1 proteins with telomere DNA
    Mark Corriveau
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106, USA
    J Biol Chem 288:16361-70. 2013

Collaborators

  • Malligarjunan Rajavel
  • Michael R Mullins
  • Mark Corriveau
  • Michael E Harris
  • Diane Baus

Detail Information

Publications3

  1. pmc Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA
    Derek J Taylor
    Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 410:10-7. 2011
    ..The results revealed that POT1-N and POT1-TPP1 can completely coat long telomeric ssDNA substrates. Furthermore, we show that ssDNA coated with human POT1-TPP1 heterodimers forms compact, potentially ordered structures...
  2. pmc Multiple facets of TPP1 in telomere maintenance
    Malligarjunan Rajavel
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland OH 44106, USA
    Biochim Biophys Acta 1844:1550-9. 2014
    ..In this review, we summarize the current knowledge regarding the role of TPP1 in telomere maintenance. ..
  3. pmc Coordinated interactions of multiple POT1-TPP1 proteins with telomere DNA
    Mark Corriveau
    Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106, USA
    J Biol Chem 288:16361-70. 2013
    ..Together, these data suggest that POT1-TPP1 binds telomeric DNA in a coordinated manner to facilitate assembly of the nucleoprotein complexes into a state that is more accessible to enzymatic activity...