Research Topics
| Lynn SingerSummaryAffiliation: Case Western Reserve University Country: USA Publications
Research Grants
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Detail Information
Publications
One-year outcomes of prenatal exposure to MDMA and other recreational drugsLynn T Singer
Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, Ohio 44106, USA
Pediatrics 130:407-13. 2012..Preclinical studies found prenatal exposure related to long-term learning and memory impairments. There are no studies of sequelae of prenatal MDMA exposure in humans, despite potential harmful effects to the fetus...- Neurobehavioral outcomes of infants exposed to MDMA (Ecstasy) and other recreational drugs during pregnancyLynn T Singer
Department of Environmental Health Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
Neurotoxicol Teratol 34:303-10. 2012..These findings suggest risk to the developing infant related to MDMA exposure and warrant continued follow-up to determine whether early motor delays persist or resolve... - Prenatal cocaine exposure: drug and environmental effects at 9 yearsLynn T Singer
Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA
J Pediatr 153:105-11. 2008..To assess school-age cognitive and achievement outcomes in children with prenatal cocaine exposure, controlling for confounding drug and environmental factors... 
Cognitive outcomes of preschool children with prenatal cocaine exposureLynn T Singer
Department of General Medical Sciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
JAMA 291:2448-56. 2004..Because of methodological limitations, the results of the few prospective studies assessing long-term cognitive effects of prenatal cocaine exposure are inconsistent...- Parenting very low birth weight children at school age: maternal stress and copingLynn T Singer
Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
J Pediatr 151:463-9. 2007..To compare severity and determinants of stress and coping in mothers of 8-year-old very low birth weight (VLBW) and term children varying in medical and developmental risk... 
Longitudinal predictors of maternal stress and coping after very low-birth-weight birthLynn T Singer
Department of General Medical Sciences, Case Western Reserve University, 11400 Euclid Ave, Cleveland, OH 44106, USA
Arch Pediatr Adolesc Med 164:518-24. 2010..To determine longitudinal outcomes and contributors to parental stress and coping in mothers of very low-birth-weight (VLBW) children...- Autonomic alterations in cocaine-exposed infantsSudhir Ken Mehta
Fairview Hospital and MetroHealth Medical Center, Cleveland, Ohio 44111 5656, USA
Am Heart J 144:1109-15. 2002..It is unknown whether these alterations are transient (acute effect) or persist in older infants and possibly reflect a teratogenic effect of cocaine... - Cognitive and motor outcomes of cocaine-exposed infantsLynn T Singer
Department of Pediatrics, Case Western Reserve University, Triangle Bldg, 11400 Euclid Ave, Suite 250 A, Cleveland, OH 44106, USA
JAMA 287:1952-60. 2002..Few longitudinal studies have examined cocaine-exposed infants, however, and findings are contradictory because of methodologic limitations... - Cocaine, anemia, and neurodevelopmental outcomes in children: a longitudinal studySuchitra Nelson
Department of Community Dentistry, School of Dentistry, Case Western Reserve University, Cleveland, Ohio 44106 4905, USA
J Dev Behav Pediatr 25:1-9. 2004..These findings indicate the need for greater pediatric surveillance of IDA and lead in cocaine-exposed infants, in order to reduce long-term neuropsychological deficits... - Prenatal cocaine/polydrug exposure and infant performance on an executive functioning taskJulia S Noland
Department of Pediatrics and General Medical Sciences, Case Western Reserve University, USA
Dev Neuropsychol 24:499-517. 2003.... - Effects of infant risk status and maternal psychological distress on maternal-infant interactions during the first year of lifeLynn T Singer
Departments of Pediatrics and General Medical Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
J Dev Behav Pediatr 24:233-41. 2003..Because maternal distress is more prevalent in mothers of VLBW infants postpartum, intervention efforts should focus on assessment of maternal distress and the challenges posed by the interactive behaviors of VLBW infants... - Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implicationsSonia Minnes
Mandel School of Applied Social Sciences Case Western Reserve University, Cleveland, Ohio 44106, USA
Addict Sci Clin Pract 6:57-70. 2011..We review treatment options for pregnant, substance-dependent women and therapeutic interventions for exposed children... - Four-year language outcomes of children exposed to cocaine in uteroBarbara A Lewis
Department of Pediatrics, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106, USA
Neurotoxicol Teratol 26:617-27. 2004..These findings support a cocaine-specific effect on language skills in early childhood that may be modified with an enriched environment... - A longitudinal case study of a child with mosaic trisomy 22: language, cognitive, behavioral, physical, and dental outcomesBarbara Lewis
Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-6038, USA
Am J Med Genet A 143:2070-4. 2007 - Impact of childhood abuse and neglect on substance abuse and psychological distress in adulthoodMeeyoung Min
Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 7164, USA
J Trauma Stress 20:833-44. 2007..Findings indicate the need for supportive educational strategies and interventions to teach coping skills in preventing substance abuse and longer-term psychological distress in children exposed to trauma... - Developmental sequelae in preterm infants having a diagnosis of bronchopulmonary dysplasia: analysis using a severity-based classification systemElizabeth J Short
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106, USA
Arch Pediatr Adolesc Med 161:1082-7. 2007..To investigate the relationship between the severity-based definition of bronchopulmonary dysplasia (BPD), choice of treatment, and neurocognitive outcomes at age 3 and 8 years... - The association of prenatal cocaine use and childhood trauma with psychological symptoms over 6 yearsSonia Minnes
Department of General Medical Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
Arch Womens Ment Health 11:181-92. 2008.... - Cognitive development and low-level lead exposure in poly-drug exposed childrenMeeyoung O Min
Case Western Reserve University School of Medicine, Department of Pediatrics, Cleveland, OH 44106 7164, USA
Neurotoxicol Teratol 31:225-31. 2009.... - The effects of prenatal cocaine exposure on problem behavior in children 4-10 yearsSonia Minnes
Case Western Reserve University, The Mandel School of Applied Social Science, Cleveland, Ohio 44106, USA
Neurotoxicol Teratol 32:443-51. 2010..Children prenatally exposed to cocaine may be at increased risk for behavioral problems due to disruptions of monaminergically regulated arousal systems and/or environmental conditions... - Prenatal cocaine and tobacco effects on children's language trajectoriesBarbara A Lewis
Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
Pediatrics 120:e78-85. 2007..The objective of this study was to examine the effects of prenatal cocaine and polydrug exposure on language development of preschool children using a prospective longitudinal model, controlling for confounders... - Effects of cocaine/polydrug exposure and maternal psychological distress on infant birth outcomesLynn T Singer
Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
Neurotoxicol Teratol 24:127-35. 2002..In addition, maternal distress symptoms, which may be reflective of maternal mental health disorders or responses to stress, added significantly to the risk for poorer fetal growth... - Cognitive and academic consequences of bronchopulmonary dysplasia and very low birth weight: 8-year-old outcomesElizabeth J Short
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106, USA
Pediatrics 112:e359. 2003..To examine the effects of bronchopulmonary dysplasia (BPD) and very low birth weight (VLBW) on the cognitive and academic achievement of a large sample of 8-year-old children... - Mental health outcomes of cocaine-exposed children at 6 years of ageTeresa J Linares
Department of Psychology, Case Western Reserve University, USA
J Pediatr Psychol 31:85-97. 2006..To assess 6-year-old cocaine- and noncocaine-exposed children's mental health outcomes controlling for potential confounders... - Executive functioning in preschool-age children prenatally exposed to alcohol, cocaine, and marijuanaJulia S Noland
Case Western Reserve University, Cleveland, Ohio, USA
Alcohol Clin Exp Res 27:647-56. 2003..However, large, adequately controlled, prospective studies of alcohol and marijuana effects on EF have reported conflicting findings, and there have been no such studies of cocaine exposure... - Effects of prenatal cocaine/polydrug use on maternal-infant feeding interactions during the first year of lifeSonia Minnes
Department of General Medical Sciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Dev Behav Pediatr 26:194-200. 2005..Maternal cocaine use during pregnancy and other pre- and postnatal factors adversely affect maternal-infant interactions during the first year of life... - Fatty Acid ethyl esters: quantitative biomarkers for maternal alcohol consumptionCynthia F Bearer
Department of Pediatrics, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
J Pediatr 146:824-30. 2005..To develop a laboratory marker to identify newborns exposed to alcohol... - Dysmorphic and anthropometric outcomes in 6-year-old prenatally cocaine-exposed childrenSonia Minnes
Department of General Medical Sciences, Case Western Reserve University, 11400 Euclid Avenue, The Triangle, Suite 250, Cleveland, OH 44106, USA
Neurotoxicol Teratol 28:28-38. 2006..These finding indicate that prenatal cocaine exposure has a negative effect on specific growth outcomes including standardized height and weight for height, but not a systematic pattern of structural abnormalities... - Psychometric properties of the Dominic interactive assessment: a computerized self-report for childrenTeresa J Linares Scott
Case Western Reserve University, Cleveland, OH 44106, USA
Assessment 13:16-26. 2006..Overall, low correlations were obtained, which are comparable to other studies that evaluate agreement between child and parent report of behaviors... - The effects of prenatal cocaine on language development at 10 years of ageBarbara A Lewis
Department of Communication Sciences, Case Western Reserve University, Cleveland, OH 44106, USA
Neurotoxicol Teratol 33:17-24. 2011..To examine the long term effects of prenatal cocaine exposure (PCE) on the language development of 10-year-old children utilizing a prospective design, controlling for confounding drug and environmental factors... - Speech and language outcomes of children with bronchopulmonary dysplasiaBarbara A Lewis
Department of Pediatrics, School of Medicine, Behavioral Pediatrics and Psychology 6038, Rainbow Babies and Childrens Hospital, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
J Commun Disord 35:393-406. 2002..2) As a result of this activity the reader will be able to discuss how children with VLBW with BPD differ from children with VLBW without BPD in their developmental outcomes... - Factor structure of coping: two studies of mothers with high levels of life stressSheri P Eisengart
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
Psychol Assess 18:278-88. 2006..CFA results revealed a moderately good fit, confirming the factor structure in a 2nd, independent sample of mothers with high levels of life stress... - Psychosocial and behavioral factors related to the post-partum placements of infants born to cocaine-using womenSonia Minnes
Department of General Medical Sciences, Case Western Reserve University, Cleveland, OH, USA
Child Abuse Negl 32:353-66. 2008..A second objective was to evaluate the relative contribution of psychosocial factors to infant placement... - Prospective patterns and correlates of quality of life among women in substance abuse treatmentElizabeth M Tracy
Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 7164, USA
Drug Alcohol Depend 124:242-9. 2012..To date however, QOL remains an under investigated area in the addictions field, especially in the United States... - Diastolic alterations in infants exposed to intrauterine cocaine: a follow-up study by color kinesisSudhir Ken Mehta
Fairview Hospital and MetroHealth Medical Center, Cleveland, Ohio 44111, USA
J Am Soc Echocardiogr 15:1361-6. 2002..It is unknown whether these abnormalities are transient because of short-term effects or persist in older infants, possibly reflecting a teratogenic effect of cocaine... - Fatty acid ethyl esters in meconium are associated with poorer neurodevelopmental outcomes to two years of ageJennifer Peterson
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
J Pediatr 152:788-92. 2008..To determine the relationship between fatty acid ethyl esters (FAEE) in meconium and neurodevelopment in infants exposed to alcohol in utero at 6.5 months, 1 year, and 2 years of age... - Psychosocial profiles of older adolescent MDMA usersLynn T Singer
Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
Drug Alcohol Depend 74:245-52. 2004..Using a case-control design, patterns of drug use, psychological symptoms, and behavioral characteristics associated with 3,4-methylenedioxymethamphetamine (MDMA ) use were surveyed in a sample of older adolescents (median age 20)... - Children prenatally exposed to cocaine: developmental outcomes and environmental risks at seven years of ageRobert E Arendt
The Buckeye Ranch, Columbus, Ohio, USA
J Dev Behav Pediatr 25:83-90. 2004.... - Prenatal drug exposure and selective attention in preschoolersJulia S Noland
Vanderbilt University, Department of Psychology and Human Development, Peabody College 512, 230 Appleton Place, Nashville, TN 37203 5701, USA
Neurotoxicol Teratol 27:429-38. 2005..Substance exposure effects were independent of maternal postpartum psychological distress, birth mother cognitive functioning, current caregiver functioning, other substance exposures and child concurrent verbal IQ... - Neuroimaging of prenatal drug exposureDiana L Dow-Edwards
Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
Neurotoxicol Teratol 28:386-402. 2006
Research Grants
- COCAINE EXPOSED INFANTS AND THEIR MOTHERSLynn Singer; Fiscal Year: 2002....
- Developmental Outcomes of Prenatal Exposure to MDMA ('E*Lynn Singer; Fiscal Year: 2005....
- Cocaine Exposed Children at School AgeLynn Singer; Fiscal Year: 2006..abstract_text> ..