Mark S Scher

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Temperature differences during sleep between fullterm and preterm neonates at matched post-conceptional ages
    Mark S Scher
    Division of Pediatric Neurology, Developmental Neurophysiology Laboratories, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106 6090, USA
    Clin Neurophysiol 114:17-22. 2003
  2. ncbi request reprint Cerebral infarctions in the fetus and neonate: maternal-placental-fetal considerations
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Fetal and Neonatal Neurology Programs, Rainbow Babies and Children s Hospital, 11100 Euclid Avenue, Cleveland, OH 44106 6005, USA
    Clin Perinatol 29:693-724, vi-vii. 2002
  3. ncbi request reprint Delayed onset of status epilepticus after transient asphyxia in an asymptomatic full-term neonate
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106 6090, USA
    J Child Neurol 17:780-3. 2002
  4. ncbi request reprint Functional brain maturation in neonates as measured by EEG-sleep analyses
    Mark S Scher
    Developmental Neurophysiology Laboratory, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Avenue, OH 44106 6090, USA
    Clin Neurophysiol 114:875-82. 2003
  5. ncbi request reprint Pediatric epilepsy evaluations from the prenatal perspective
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital MacDonald Hospital for Women, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Child Neurol 22:396-401. 2007
  6. ncbi request reprint Automated state analyses: proposed applications to neonatal neurointensive care
    Mark S Scher
    Department of Pediatrics, School of Medicine, Rainbow Babies and Children s Hospital, and Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Neurophysiol 22:256-70. 2005
  7. ncbi request reprint Prediction of neonatal state and maturational change using dimensional analysis
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Schools of Medicine and Engineering, Case Western Reserve University, Cleveland, Ohio 44106 6090, USA
    J Clin Neurophysiol 22:159-65. 2005
  8. ncbi request reprint Neonatal seizure classification: a fetal perspective concerning childhood epilepsy
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, CWRU School of Medicine, 11100 Euclid Avenue, M S 6090, Cleveland, OH 44106, USA
    Epilepsy Res 70:S41-57. 2006
  9. ncbi request reprint Pediatric neurology participation in a fetal diagnostic service
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    Pediatr Neurol 30:338-44. 2004
  10. ncbi request reprint Neurophysiologic assessment of neonatal sleep organization: preliminary results of a randomized, controlled trial of skin contact with preterm infants
    Susan M Ludington-Hoe
    School of Nursing, Case Western Reserve University, Cleveland, Ohio 44106 4904, USA
    Pediatrics 117:e909-23. 2006

Detail Information

Publications32

  1. ncbi request reprint Temperature differences during sleep between fullterm and preterm neonates at matched post-conceptional ages
    Mark S Scher
    Division of Pediatric Neurology, Developmental Neurophysiology Laboratories, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106 6090, USA
    Clin Neurophysiol 114:17-22. 2003
    ..The present study examines if differences in state-specific temperature changes exist in a healthy preterm cohort as another expression of brain dysmaturity...
  2. ncbi request reprint Cerebral infarctions in the fetus and neonate: maternal-placental-fetal considerations
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Fetal and Neonatal Neurology Programs, Rainbow Babies and Children s Hospital, 11100 Euclid Avenue, Cleveland, OH 44106 6005, USA
    Clin Perinatol 29:693-724, vi-vii. 2002
    ..Comprehensive evaluations of survivors of cerebral infarction are needed to better understand structural and functional plasticity of the developing brain after a cerebrovascular event in the fetal and neonatal periods...
  3. ncbi request reprint Delayed onset of status epilepticus after transient asphyxia in an asymptomatic full-term neonate
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106 6090, USA
    J Child Neurol 17:780-3. 2002
    ..This child's clinical presentation highlights the delayed reperfusion phase after ischemia-induced brain injury...
  4. ncbi request reprint Functional brain maturation in neonates as measured by EEG-sleep analyses
    Mark S Scher
    Developmental Neurophysiology Laboratory, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Avenue, OH 44106 6090, USA
    Clin Neurophysiol 114:875-82. 2003
    ..Seven measures of neonatal EEG-sleep behavior were evaluated using multivariate analyses to ascertain if physiologic differences exist between healthy full- and preterm cohorts...
  5. ncbi request reprint Pediatric epilepsy evaluations from the prenatal perspective
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital MacDonald Hospital for Women, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Child Neurol 22:396-401. 2007
    ..Dual pathology should include prenatal contributions to childhood epilepsy on both a genetic and acquired basis. Epileptologists should consider an ontogenetic approach to study the epileptic condition from a fetal neurology perspective...
  6. ncbi request reprint Automated state analyses: proposed applications to neonatal neurointensive care
    Mark S Scher
    Department of Pediatrics, School of Medicine, Rainbow Babies and Children s Hospital, and Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Neurophysiol 22:256-70. 2005
    ....
  7. ncbi request reprint Prediction of neonatal state and maturational change using dimensional analysis
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Schools of Medicine and Engineering, Case Western Reserve University, Cleveland, Ohio 44106 6090, USA
    J Clin Neurophysiol 22:159-65. 2005
    ..These findings support the concept of physiologic dysmaturity for the preterm neonate as a reflection of altered neural plasticity of the brain as a result of the conditions of prematurity...
  8. ncbi request reprint Neonatal seizure classification: a fetal perspective concerning childhood epilepsy
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, CWRU School of Medicine, 11100 Euclid Avenue, M S 6090, Cleveland, OH 44106, USA
    Epilepsy Res 70:S41-57. 2006
    ..Developmental neural plasticity also extends into adulthood when brain remodeling mechanisms further contribute to epileptogenesis and continues to impair quality of life...
  9. ncbi request reprint Pediatric neurology participation in a fetal diagnostic service
    Mark S Scher
    Department of Pediatrics, Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    Pediatr Neurol 30:338-44. 2004
    ..Postnatal diagnoses may be different from the fetal diagnoses which will influence continuity of care for the child at older ages...
  10. ncbi request reprint Neurophysiologic assessment of neonatal sleep organization: preliminary results of a randomized, controlled trial of skin contact with preterm infants
    Susan M Ludington-Hoe
    School of Nursing, Case Western Reserve University, Cleveland, Ohio 44106 4904, USA
    Pediatrics 117:e909-23. 2006
    ..Important differences exist between behavioral and electroencephalographic/polysomnographic definitions of sleep state...
  11. pmc Neurophysiologic assessment of brain maturation after an 8-week trial of skin-to-skin contact on preterm infants
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, OH 44106, USA
    Clin Neurophysiol 120:1812-8. 2009
    ..Skin-to-skin contact (SSC) promotes physiological stability and interaction between parents and infants. Analyses of EEG-sleep studies can compare functional brain maturation between SSC and non-SSC cohorts...
  12. pmc Physiologic brain dysmaturity in late preterm infants
    Mark S Scher
    Department of Pediatric Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    Pediatr Res 70:524-8. 2011
    ..Altered EEG/Sleep behaviors in the LPT are biomarkers of developmental neuroplasticity involving interconnected neuronal networks adapting to conditions of prematurity for this largest segment of the preterm neonatal population...
  13. doi request reprint Neonatal EEG/sleep state analyses: a complex phenotype of developmental neural plasticity
    Mark S Scher
    Division of Pediatric Neurology, Programs of Fetal Neonatal Neurology, Laboratory for Computational Neuroscience, Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Dev Neurosci 31:259-75. 2009
    ....
  14. ncbi request reprint Cyclicity of neonatal sleep behaviors at 25 to 30 weeks' postconceptional age
    Mark S Scher
    Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Pediatr Res 57:879-82. 2005
    ..Sleep state cyclicity is expressed for a majority of neonates between 25 and 30 wk PCA, reflecting an ultradian biologic rhythm during the early perinatal stage of brain development...
  15. ncbi request reprint Ontogeny of EEG-sleep from neonatal through infancy periods
    Mark S Scher
    Division of Pediatric Neurology, Laboratory for Computational Neuroscience, Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106 6090, USA
    Sleep Med 9:615-36. 2008
    ..Computational strategies may ultimately improve our diagnostic skills to identify special-needs children and to track the neurorehabilitative care of the high-risk fetus, neonate, and infant...
  16. doi request reprint An interdisciplinary fetal/neonatal neurology program
    Mark S Scher
    Division of Pediatric Neurology, Pediatrics and Neurology School of Medicine, Case Western Reserve University, Fetal Neonatal Neurology Program, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Cleveland, OH 44106, USA
    J Child Neurol 27:496-502. 2012
    ....
  17. ncbi request reprint Automated EEG-sleep analyses and neonatal neurointensive care
    Mark S Scher
    Rainbow Babies and Children s Hospital, 11100 Euclid Avenue, M S 6090, Cleveland, OH 44106, USA
    Sleep Med 5:533-40. 2004
    ....
  18. doi request reprint Timing of neonatal seizures and intrapartum obstetrical factors
    Mark S Scher
    Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106 6090, USA
    J Child Neurol 23:640-3. 2008
    ..Factors other than intrapartum events more likely contribute to the encephalopathic repertoire of the newborn, including seizures...
  19. ncbi request reprint Fetal and neonatal neurologic case histories: assessment of brain disorders in the context of fetal-maternal-placental disease. Part 2: Neonatal neurologic consultations in the context of adverse antepartum and intrapartum events
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, OH 44106, USA
    J Child Neurol 18:155-64. 2003
    ..Documentation of the neonate's neurologic condition, together with knowledge of maternal, fetal, and placental diseases, will help anticipate neuroresuscitative decisions, as well as subsequent neurologic deficits...
  20. ncbi request reprint Neonatal seizures and brain damage
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    Pediatr Neurol 29:381-90. 2003
    ....
  21. doi request reprint Peripartum consultations expand the role of the fetal/neonatal neurologist
    Mark S Scher
    School of Medicine, Case Western Reserve University, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, USA
    Pediatr Neurol 47:411-8. 2012
    ..Appropriate choices of preventive, rescue, and repair neuroprotective interventions must consider both the timing and etiologies of encephalopathies in the context of maternal, fetal, placental, and neonatal diseases...
  22. doi request reprint Developmental origins of cerebrovascular disease I: prenatal cerebrovascular development--classic findings in the context of advances in genetic and fetal surveillance evaluations
    Mark S Scher
    School of Medicine, Case Western Reserve University, and Division of Pediatric Neurology, Fetal Neonatal Neurology Program, Rainbow Babies and Children s Hospital, Case Medical Center, University Hospitals of Cleveland, Cleveland, OH, USA
    J Child Neurol 27:121-31. 2012
    ..Studies of positive and negative effects of neuroplasticity during early life must then consider ongoing gene-environment interactions during childhood and adulthood that either sustain neurologic health or contribute to disease...
  23. ncbi request reprint Maternal ulcerative colitis and fetal brain injury: long-term neurologic outcome
    Mark S Scher
    Rainbow Babies and Children s Hospital, Cleveland, Ohio, USA
    J Child Neurol 22:1293-6. 2007
    ..Identification of thrombophilia in the pregnant woman with active ulcerative colitis may better explain a pathophysiologic mechanism for long-term neurological morbidity in offspring...
  24. ncbi request reprint Fetal and neonatal neurologic case histories: assessment of brain disorders in the context of fetal-maternal-placental disease. Part 1: Fetal neurologic consultations in the context of antepartum events and prenatal brain development
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children Hospital, Cleveland, Ohio, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    J Child Neurol 18:85-92. 2003
    ..The pediatric neurologist has the opportunity to provide an important consultative role, bridging prenatal to neonatal life and integrating medical and ethical concerns for the child in the context of the family...
  25. ncbi request reprint Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use
    Mark S Scher
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Pediatr Neurol 28:277-80. 2003
    ..Serial electroencephalographic monitoring helps document continued electrographic seizure expression after antiepileptic drug use, following complete or partial suppression of clinical seizure behaviors...
  26. ncbi request reprint Prenatal contributions to epilepsy: lessons from the bedside
    Mark S Scher
    Case Western Reserve University, Ohio, USA
    Epileptic Disord 5:77-91. 2003
    ..Translational research from bench to bedside should consider the acquired causes of pediatric and adult epilepsies in the context of the patient's genetic environment...
  27. ncbi request reprint Fetal neurologic consultations
    Mark S Scher
    Department of Pediatrics, Rainbow Babies and Children s Hospital, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 6090, USA
    Pediatr Neurol 29:193-202. 2003
    ..Evaluation of future strategies for either fetal or neonatal brain resuscitation will need to consider the developmental context in which a suspected brain injury occurred during the antepartum, intrapartum, and neonatal periods...
  28. doi request reprint Neonatal hypertonia: I. Classification and structural-functional correlates
    Mark S Scher
    Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106 6090, USA
    Pediatr Neurol 39:301-6. 2008
    ....
  29. doi request reprint Developmental origins of cerebrovascular disease II: considering gene-environment interactions when developing neuroprotective strategies
    Mark S Scher
    School of Medicine, Case Western Reserve University, and Division of Pediatric Neurology, Fetal Neonatal Neurology Program, Rainbow Babies and Children s Hospital, Case Medical Center, University Hospitals of Cleveland, OH, USA
    J Child Neurol 27:238-50. 2012
    ..A greater understanding of gene-environment influences on cerebrovascular health and disease in early life will contribute to the successful development of neuroprotective strategies throughout the lifespan...
  30. doi request reprint Neonatal Hypertonia: II. differential diagnosis and proposed neuroprotection
    Mark S Scher
    Program in Fetal and Neonatal Neurology, Division of Pediatric Neurology, Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106 6090, USA
    Pediatr Neurol 39:373-80. 2008
    ..Measuring the efficacy of a neuroprotection protocol should include a complete list of life-course challenges, including motor, epileptic, cognitive, and behavioral outcomes as expressed at successively older ages...
  31. ncbi request reprint Relation of sleep state to hypoxemic episodes in ventilated extremely-low-birth-weight infants
    Liisa Lehtonen
    Department of Pediatrics Neonatology, Pediatric Neurology, Rainbow Babies and Childrens Hospital, Cleveland, Ohio 44106, USA
    J Pediatr 141:363-8. 2002
    ..Nonparametric statistics were used to test for differences in the proportion of time hypoxemic (oxygen saturation </=85%) between behavioral states...
  32. ncbi request reprint Effects of antenatal magnesium sulfate and corticosteroid therapy on sleep states of preterm infants
    Beth Black
    CB 7460, School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7460, USA
    Res Nurs Health 29:269-80. 2006
    ..The MgSO4 -only group had higher quiet sleep regularity scores and fewer state changes. These findings suggest that fetal exposure to MgSO4 may subtly affect the central nervous system...